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HDAC and MEK inhibition synergistically suppresses HOXC6 and enhances PD-1 blockade efficacy in BRAFV600E-mutant microsatellite stable colorectal cancer
Published 2025-01-01“…Background B-Raf proto-oncogene, serine/threonine kinase (BRAF)V600E-mutant microsatellite stable (MSS) colorectal cancer (CRC) constitutes a distinct CRC subgroup, traditionally perceived as minimally responsive to standard therapies. …”
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3942
Electroacupuncture Increases the Hippocampal Synaptic Transmission Efficiency and Long-Term Plasticity to Improve Vascular Cognitive Impairment
Published 2022-01-01“…This study is aimed at investigating the mechanisms underlying the effects of EA treatment on hippocampal synaptic transmission efficiency and plasticity in rats with VCI. Methods. Sprague–Dawley rats were subjected to VCI with bilateral common carotid occlusion (2VO). …”
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3943
Popliteal artery aneurysm is a cause that should not be forgotten in acute limb ischemia
Published 2024-03-01“…The etiology of ALI was identified as thromboembolic events secondary to atherosclerotic peripheral artery disease (APAD) in 92 patients (89.3%), and as PAA in 11 patients (10.7%). …”
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A mulher como produto de satisfação masculina na pornografia: uma análise histórico-social
Published 2020-11-01Get full text
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3946
Siyer Anlatımında Öne Çıkan Dört Eserin Üslup, İçerik ve Metin Açısından Değerlendirilip Karşılaştırılması
Published 2023-07-01“…Muhammed ve Evrensel Mesajı ve Âdem Apak’ın Siyer-i Nebi adlı eserleri ele alınmıştır.…”
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3947
Empowerment key factors in shaping women's awareness of household waste management
Published 2021-07-01Get full text
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3948
Food Intake and Core Body Temperature of Pups and Adults in a db Mouse Line Deficient in the Long Form of the Leptin Receptor without Misty Mutation
Published 2018-01-01“…Additionally, db/db mice displayed significantly lower mRNA levels of brown adipose tissue uncoupling protein 1 at both ages. …”
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3949
Low Profile Planar Inverted-L Antenna (PILA) for UHF RFID Tag on Signal Absorption and Reflection Surfaces
Published 2025-01-01Subjects: Get full text
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3950
تعیین فرکانس طبیعی خاک شهر بهبهان با استفاده از تحلیل دادههای میکروترمور
Published 2024-01-01Get full text
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3951
Effect of Posterior Corneal Surgically Induced Astigmatism on Toric Intraocular Lens Power Calculations
Published 2025-01-01Get full text
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3952
H.A.R. Gibb ve Onun Arap Dili ve Kur’an Bağlamında İslâm Algısı
Published 2018-08-01Get full text
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Climatic Background and Prediction of Boreal Winter PM2.5 Concentrations in Hubei Province, China
Published 2025-01-01“…Conversely, the South Atlantic–Southwest Indian Ocean SST mode (SAIO) and the Ross Sea sea-ice mode (ROSIC) contribute to more stable local atmospheric conditions, which reduce pollutant dispersion and increase PM2.5 accumulation, thus exhibiting a positive correlation with DJF-HBPMC. (3) A multiple linear regression (MLR) model, using selected seasonal SST and SIC indices, effectively predicts DJF-HBPMC, showing high correlation coefficients (CORR) and anomaly sign consistency rates (AS) compared to real-time values. (4) In daily HBPMC forecasting, both the Reversed Unrestricted Mixed-Frequency Data Sampling (RU-MIDAS) and Reversed Restricted-MIDAS (RR-MIDAS) models exhibit superior skill using only monthly precipitation, and the RR-MIDAS offers the best balance in prediction accuracy and trend consistency when incorporating monthly precipitation along with monthly SST and SIC indices.…”
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Formación en reputación. Análisis de los principales MBA en México
Published 2022-03-01“…Originalidad/contribución: Esta investigación pretende contribuir a mejorar la formación que reciben actualmente los altos ejecutivos en este país, de manera que puedan estar más capacitados para enfrentar los retos que presenta el entorno actual para los negocios.…”
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Targeting AI-2 quorum sensing: harnessing natural products against Streptococcus suis biofilm infection
Published 2025-02-01Get full text
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