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Nutritional Status of Children with Beta Thalassemia Major
Published 2023-12-01Get full text
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Local Leadership During the Territorial Amalgamation Process – The Case of Latvia
Published 2023-05-01Get full text
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Duodenum and ascending colonal perforation due to biliary stent migration
Published 2025-01-01Get full text
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Mechanism of Substrate Activation by Tryptophan Hydroxylase: A Computational Study
Published 2025-01-01Get full text
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The effect of an 8-month exercise program on bone density and some physical characteristics in sedentary women
Published 2016-05-01“…Total bone mineral density (BMD), total bone mineral content (BMC), T score, Z score, Total lean mass, total fat mass and total fat percentile values were diagnosed by dual X-ray absorptiometry (DXA) (Norland XR-46). Wilcoxon signed rank test was used for data evaluation and significance level alpha was set at 0.05. …”
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Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head necrosis
Published 2025-01-01“…ALP and Alizarin Red staining evaluated osteoblast differentiation and mineralization.ResultsNetwork pharmacology identified curcumin, berberine, and diosgenin as key active components of SBD, with the PI3K/Akt and VEGFR pathways as critical targets, and RAF1, FOXO3, and BRAF as hub genes. In vivo, SBD intervention significantly reduced bone structural damage and apoptosis, decreasing the rate of empty bone lacunae. …”
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Integrated serum metabolomics and network pharmacology reveal molecular mechanism of Qixue Huazheng formula on peritoneal fibrosis
Published 2025-01-01“…Metabolite-target network and molecular docking analyses revealed that QXHZF can bind to estrogen receptor 1 (ESR1) and rapidly accelerated fibrosarcoma 1 (RAF1) through its components. WB demonstrated that QXHZF treatment reversed activation of the above-mentioned signaling pathways, thereby inhibiting PD fluid-induced PF.ConclusionQXHZF can significantly ameliorate PD-induced PF and may regulate estrogen signaling, the Ras pathway, and apoptosis in this context.…”
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Spatial Distribution Characteristics of Micronutrients and Their Deficiency Effect on the Root Morphology and Architecture in Citrus Rootstock
Published 2025-01-01“…To clarify the spatial distribution characteristics of essential nutrients in citrus roots and the influence mechanism of micronutrient deficiency on citrus root morphology and architecture, especially the effects on lateral root (LR) growth and development, two commonly used citrus rootstocks, trifoliate orange (<i>Poncirus trifoliata</i> L. Raf., Ptr) and red tangerine (<i>Citrus reticulata</i> Blanco, Cre), were employed here. …”
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Size effect-based improved antioxidant activity of selenium nanoparticles regulating Anti-PI3K-mTOR and Ras-MEK pathways for treating spinal cord injury to avoid hormone shock-induced immunosuppression
Published 2025-01-01“…Ultimately, LNT-UsSeNPs directly regulated the PI3K-AKT-mTOR and Ras-Raf-MEK-ERK signaling pathways by regulating selenoproteins to achieve non-immunosuppressive anti-inflammatory therapy. …”
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Beginning criminal law /
Published 2013Table of Contents: “…Actus reus, acts, omissions and causation -- Mens rea -- Murder and involuntary manslaughter -- Voluntary manslaughter -- Defences - duress, necessity, self defence, mistake and intoxication -- Non fatal offences against the person -- Rape -- Theft -- Forms of liability - inchoate offences and joint enterprise.…”
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Differential Intestinal Mucosa Transcriptomic Biomarkers for Crohn’s Disease and Ulcerative Colitis
Published 2018-01-01Get full text
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