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  1. 301

    Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors by Michael Hoffmeister, Hermann Brenner, Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Julien Taieb, David Tougeron, Robyn L Ward, Marco Vitellaro, Thierry André, Pierre Laurent-Puig, Jitendra Jonnagaddala, Francesca Bergamo, Raghav Sundar, Claire Gallois, Michael J Overman, Jakob Nikolas Kather, Lisa Salvatore, Romain Cohen, Rossana Intini, Priya Jayachandran, Miriam Koopman, Javier Ros, Marwan Fakih, Vincenzo Nasca, Giacomo Mazzoli, Jeanine M L Roodhart, Filippo Ghelardi, Elena Elez, Durgesh Wankhede, Marta Ligero, Joseph Zhao, Koen Zwart, Jeroen Derksen, Nicholas Hawkins, Javier Carmona

    Published 2025-02-01
    “…Growing evidence supports the role of sex in determining susceptibility to anticancer therapies, but data is lacking for patients with MSI-H CRC.Methods In this real-world cohort comprising 624 patients with MSI-H mCRC receiving ICIs, we investigated the impact of sex on patients’ outcomes, overall and according to RAS-BRAF mutational status or type of treatment (anti-PD-(L)1 with or without anti-CTLA-4 agents). …”
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  2. 302

    Peningkatan Performa Komputasi Sistem Navigasi Transportasi Publik Pada Perangkat Bergerak Melalui Penerapan Teknik Kompresi Data dan Penyederhanaan Graf by Aryo Pinandito, Agi Putra Kharisma, Muhammad Aminul Akbar, Mochamad Chandra Saputra

    Published 2024-12-01
    “…Selain itu, dengan penyederhanaan graf secara visual, waktu proses yang diperlukan untuk merekomendasikan rute transportasi menjadi lebih singkat 81,24% serta berkurangnya penggunaan memori hingga 72,99%.   …”
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    Keratitis-Ichthyosis-Deafness Syndrome, Atypical Connexin GJB2 Gene Mutation, and Peripheral T-Cell Lymphoma: More Than a Random Association? by Claudio Fozza, Fausto Poddie, Salvatore Contini, Antonio Galleu, Francesca Cottoni, Maurizio Longinotti, Francesco Cucca

    Published 2011-01-01
    “…Keratitis-ichthyosis-deafness (KID) syndrome is a rare congenital disorder characterized by skin lesions, neurosensorial hypoacusia, and keratitis, usually due to the c.148G→A mutation involving the connexin 26 gene. …”
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    Physical education teachers; physical activity level and affecting factors (the example of Çanakkale) by Gulsah Sahın, Haydar Durukan, Omer Durukan

    Published 2016-05-01
    Subjects: “…exercise; ipaq; physical activity levels; physical education teachers…”
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    Comparative efficacy of sleep positional therapy, oral appliance therapy, and CPAP in obstructive sleep apnea: a meta-analysis of mean changes in key outcomes by Yunjun Gao, Sixiang Zhu, Wenjun Li, Youqing Lai

    Published 2025-02-01
    “…BackgroundObstructive sleep apnea (OSA) is commonly treated with continuous positive airway pressure (CPAP), though many patients struggle with adherence. …”
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