Showing 1 - 20 results of 4,859 for search 'RPAF~', query time: 2.78s Refine Results
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    Receptor mechanisms of PAF mediated lymphatic constriction in the canine forelimb by D. E. Dobbins

    Published 1992-01-01
    “…Platelet activating factor (PAF) is a potent inflammatory lipid. In this study we assessed the ability of PAF to impact lymphatic vessel function by altering prenodal lymphatic resistance. …”
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    Is platelet activating factor (PAF) an important mediator in bronchial asthma? by R. H. Gundel, H. O. Heuer, L. G. Letts

    Published 1992-01-01
    “…The development of selective PAF receptor antagonists may provide a novel approach to the treatment of human bronchial asthma. …”
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    Cytokine gene regulation by PGE2, LTB4 and PAF by M. Rola-Pleszczynski, J. Stankova

    Published 1992-01-01
    “…We focused on the regulatory effects of LTB4, PGE2 and PAF on cytokine gene expression.…”
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    Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation by Jie Ruan, Xuxia Wei, Suizhi Li, Zijian Ye, Linyi Hu, Ru Zhuang, Yange Cao, Shaozhou Wang, Shengpeng Wu, Dezhi Peng, Shangwu Chen, Shaochun Yuan, Anlong Xu

    Published 2025-01-01
    “…Abstract Apoptotic protease activating factor 1 (Apaf-1) was traditionally defined as a scaffold protein in mammalian cells for assembling a caspase activation platform known as the ‘apoptosome’ after its binding to cytochrome c. …”
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    Role of endogenous nitric oxide on PAF-induced vascular and respiratory effects by M. Clement, M. Albertini

    Published 1995-01-01
    “…The involvement of endogenous NO in PAF-induced shock and airway hyperresponsiveness was also studied. …”
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    Changes and Relationship of PAF and TNF in Rats with Myocardial Ischaemia and Reperfusion Injury by Ya-Ling Han, Shao-Ha Li, Qin-Yue Zheng, Hong-Bin Wang, Guo-Yan Zhang, Zhong-Gui Wu, Si-Cong Chen

    Published 1994-01-01
    “…In this study it is reported that: (1) the levels of blood platelet-activating factor and serum tumour necrosis factor significantly increased after coronary ligation and reperfusion, compared with sham-ligated controls, in an anaesthetized rat model; (2) compared with vehicle controls, pretreatment with the PAF antagonist BN 50739 (10 mg/kg, i.v.) produced significant decreases in infarct size (from 29.6 ± 4.0% to 22.4 ± 2.1%, p<0.05 after 3 h ligation, and from 28.5 ± 9.5% to 10.5 ± 4.5%, p<0.01 after 4 h reperfusion) and the level of serum TNF (from 10.4 ± 7.7 U/ml to 3.9 ± 4.8 U/ml, p<0.05); and (3) a significan positive correlation was found between the level of blood PAF or serum TNF and infarct size. …”
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    Interaction between PAF and human platelet membranes: a fluorescence study by Ahmad Kantar, Pier Luigi Giorgi, Giovanna Curatola, Rosamaria Fiorini

    Published 1992-01-01
    “…PAF induced a time-limited and significant increase of the lipid order in the exterior part of the membrane and a decrease in membrane heterogeneity. …”
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    Clinical Significance and Expression of PAF and TNF-alpha in Seminal Plasma of Leukocytospermic Patients by Chaodong Liu, Hongjian Liu, Xianzhong Wang, Sun Xinbo

    Published 2012-01-01
    “…Discuss the changes and roles of PAF in the reproductive tract infection by observing the expression of platelet activating factor (PAF) and tumor necrosis factor α (TNF-α) in seminal plasma of patients with leukocytospermia. …”
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    The Effect of Lyso-PAF on Ciliary Activity of Human Paranasal Sinus Mucosa in vitro by T. Ganbo, K. Hisamatsu, H. Inoue, T. Nakajima, Y. Murakami

    Published 1994-01-01
    “…The effect of lyso-PAF on ciliated cells was investigated in vitro. …”
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    Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis by Yang C, Lei C, Jing G, Xia Y, Zhou H, Wu D, Zuo J, Gong H, Wang X, Dong Y, Aidebaike D, Wu X, Song X

    Published 2025-02-01
    “…In vivo studies have shown that mice with Erbin deletion have more obvious enhanced coagulation function, and in vitro studies have shown that Erbin knockout mediated macrophage secretion of TF by activating the Ras/Raf pathway.Conclusion: Erbin reduces the coagulation activation by inhibiting TF release from macrophages.Keywords: Erbin, coagulation disorders, sepsis, tissue factor, macrophage…”
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    BRAF Inhibitors for BRAF V600E Mutant Colorectal Cancers: Literature Survey and Case Report by Yasar Subutay Peker, Mehmet Fatih Can, Ismail Hakki Ozerhan, Gokhan Yagci, Nazif Zeybek, Kutan Kavakli, Sedat Gurkok, Alper Gozubuyuk, Onur Genc, Gokhan Erdem, Ahmet Ozet, Mustafa Gerek, Yusuf Peker

    Published 2018-01-01
    “…To conclude, BRAF inhibitors alone or in combination with other drugs provide a chance for curing BRAF V600E mutant colorectal cancer patients.…”
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