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BRAF V600E Mutation in Odontogenic Keratocyst: A Systematic Review and Meta-Analysis
Published 2025-01-01Get full text
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Pharmacokinetic Evaluation of [C]CEP-32496 in Nude Mice Bearing BRAF Mutation-Induced Melanomas
Published 2018-09-01“…CEP-32496, also known as RXDX-105 or Agerafenib, is a new orally active inhibitor for the mutated v-raf murine sarcoma viral oncogene homolog B1 (BRAF V600E ), which has attracted considerable attention in clinical trials for the treatment of human cancers. …”
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Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway
Published 2025-01-01“…BackgroundThe Food and Drug Administration has approved the Serine/threonine-protein kinase B-raf (BRAF) inhibitor and Mitogen-activated extracellular signal-regulated kinase (MEK) inhibitor combo as the first-line treatment for individuals with metastatic melanoma, although the majority of these patients exhibit primary or secondary drug resistance in the clinic. …”
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Development of Space Weather Reasonable Worst‐Case Scenarios for the UK National Risk Assessment
Published 2021-04-01Get full text
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RATIONAL DRUG DESIGN OF POTENT V600E-BRAF KINASE INHIBITORS THROUGH MOLECULAR DOCKING SIMULATION
Published 2019-12-01Get full text
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ALQUR’AN DAN HADITH DALAM WACANA DELEGITIMASI NASIONALISME DI MEDIA ONLINE ISLAM
Published 2019-06-01Get full text
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Characterization of Recharge Mechanisms and Sources of Groundwater Salinization in Ras Jbel Coastal Aquifer (Northeast Tunisia) Using Hydrogeochemical Tools, Environmental Isotopes...
Published 2017-01-01“…Located in north-eastern Tunisia, the Metline-Ras Jbel-Raf Raf aquifer is a mio-plio-quaternary shallow coastal aquifer, where groundwater is the most important source of water supply. …”
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Clinicopathological and molecular analyses of uterine carcinosarcomas using next-generation sequencing: A single-center experience
Published 2023-07-01“…Aim: In this study, we aimed to perform DNA-based mutation analysis in 12 genes (KRAS, NRAS, EGFR, C-KIT, BRAF, PDGFRA, ALK, ERBB2, ERBB3, ESR1, RAF1, PIK3CA) to determine the molecular subtypes of UCS using next-generation sequencing (NGS) in patients with aggressive UCS and poor prognosis. …”
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Genetic and Biochemical Alterations in Non-Small Cell Lung Cancer
Published 2012-01-01Get full text
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Current molecular understanding of central nervous system schwannomas
Published 2025-02-01Get full text
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Histological changes in clıick bursa fabricii during postembryonic period
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