Diagnostic delay in cerebral creatine deficiency disorders: lessons learned from a cross-sectional single center study, and guanidinoacetate and creatine measurements in Switzerlan... by Christina Kaufman, Anaïs D’Andrea, Annette Hackenberg, Martin Poms, Olivier Braissant, Johannes Häberle

“…Numbers of biomarker requests showed a constant increase during the study period, with a majority of tests performed in urine, the preferred sample for CCDD detection. …”
Get full text

Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice by Chi Lieu Kim Nguyen, Yumeno Kuba, Hoai Thu Le, Hossam Hassan Shawki, Natsuki Mikami, Madoka Aoki, Nanako Yasuhara, Hayate Suzuki, Saori Mizuno-Iijima, Shinya Ayabe, Yuki Osawa, Tomoyuki Fujiyama, Tra Thi Huong Dinh, Miyuki Ishida, Yoko Daitoku, Yoko Tanimoto, Kazuya Murata, Woojin Kang, Masatsugu Ema, Yuji Hirao, Atsuo Ogura, Satoru Takahashi, Fumihiro Sugiyama, Seiya Mizuno

“…Our study reveals that the exocyst complex, a heterotetrameric protein complex important for tethering in vesicular transport, is important for proper intra-oocyte trafficking of c-KIT and GDF9 in mice. We found that depletion of oocyte-specific EXOC1, a component of the exocyst complex, impaired oocyte re-awakening and cyst breakdown, and inhibited granulosa cell proliferation during follicle growth. …”
Get full text

Effects of intracuff and intravenous lignocaine on recovery from anaesthesia after thyroid surgery. A single-centre randomised double-blind placebo-controlled trial (The IOLANT stu... by Sergey M. Efremov, Alexey Y. Kulikov, Valeria P. Govorushkina, Daniil D. Sidorov, Alexey A. Ladutko, Oleg V. Kuleshov

“…Secondary outcomes included rates of arterial hypotension, coughing during emergence, bispectral index (BIS) values, and electromyographic monitoring characteristics. …”
Get full text

The Construction of Identities in Space Inversion (the Case of Blagoveshensk and Chei-Che) by I. Y. Okunev, D. V. Basova, M. I. Tislenko

“…The research conclusions derive from series field research made in two-cities, during which some sociological and qualitative methods were used. …”
Get full text

Development and validation of a recurrence risk prediction model for elderly schizophrenia patients by Biqi Zu, Chunying Pan, Ting Wang, Hongliang Huo, Wentao Li, Libin An, Juan Yin, Yulan Wu, Meiling Tang, Dandan Li, Xin Wu, Ziwei Xie

“…Model validation was performed using 1,000 bootstrap resamples. Spatial external validation was conducted using 172 cases ESCZP from the Fourth Affiliated Hospital of Qiqihar Medical College during the same period. …”
Get full text

Body composition as an indicator of metabolic changes in mice obtained by <i>in vitro</i> fertilization by M. V. Anisimova, Yanli Gon, G. V. Kontsevaya, A. V. Romashchenko, N. V. Khotskin, A. K. Stanova, L. A. Gerlinskaya, M. P. Moshkin

“…To identify body systems subject to epigenetic transformation during in vitro fertilization (IVF), comparative morphological and functional studies were performed on sexually mature offspring of outbred CD1 mice, specific-pathogen-free (SPF), obtained by IVF (experiment) and natural conception (control). …”
Get full text

Assessment of heavy metal pollution and spatial distribution in waterfalls of Chattogram district, Bangladesh: Implications for drinking and irrigation purposes by Abdur Rouf Azad, Md. Rezaul Karim, Md. Refat Jahan Rakib, Md. Ripaj Uddin

“…The water from these waterfalls are being used by the local inhabitants for household, drinking and irrigation purposes. …”
Get full text

Effectiveness of a New Device for Hand, Wrist, and Forearm Rehabilitation: Feasibility Randomized Controlled Trial by Adriana M Ríos Rincón, Christine Guptill, Yilina Liubaoerjijin, Mathieu Figeys, Farnaz Koubasi, Geoffrey Gregson, Antonio Miguel Cruz

“…The trial design was feasible for hand intervention using the FEPSim device. The FEPSim positively affected grip strength, an objective measure of hand functioning.…”
Get full text

Endometrial Regenerative Cell-Derived Conditioned Medium Alleviates Experimental Colitis by Chenglu Sun, Jingpeng Hao, Hong Qin, Yanglin Zhu, Xiang Li, Baoren Zhang, Yafei Qin, Guangming Li, Hongda Wang, Hao Wang

“…In addition, an in vitro lymphocyte proliferation assay was measured by using a CCK-8 kit in this study. Results. ERC-CM treatment significantly improved the symptoms and histological changes in colitis mice. …”
Get full text

Will Olive Groves have a Future Under Climate Change Conditions in The North Aegean Sub-Region, a Mediterranean Agricultural Ecosystem of Türkiye? by Murat Türkeş, Sinan Şahin

“…An increase of about 6°C is expected in maximum values of maximum air temperatures during the bud swelling periods in the spring, especially after 2050 under RCP8.5 scenario. …”
Get full text

Dissolution of Different Reservoir Rocks by Organic Acids in Laboratory Simulations: Implications for the Effect of Alteration on Deep Reservoirs by Jian Chen, Jie Xu, Susu Wang, Zhenyu Sun, Zhong Li, Wanglu Jia, Ping’an Peng

“…It is difficult, however, to assess the impact of organic acid alteration on deep reservoirs because different dissolution processes may occur during diagenesis. This study simulated the dissolution of three different types of reservoir rocks by acetic acid in a closed system and compared the mineral and elemental composition, surface morphology, pore structure, and water chemistry variations of the initial and altered samples. …”
Get full text

Facilitating Large Language Model Russian Adaptation with Learned Embedding Propagation by Михаил Тихомиров, Даниил Чернышев

“…Additionally, we developed Darumeru, a new benchmark for evaluating text generation robustness during training, specifically tailored for Russian adaptation. …”
Get full text

Deformation and Failure Characteristics and Control Technology of Roadway Surrounding Rock in Deep Coal Mines by Jucai Chang, Dong Li, Tengfei Xie, Wenbao Shi, Kai He

“…Because of the unfavorable conditions in the area, overexcavation backfill technology was used. The new support was successfully applied during the subsequent construction of the rock tunnel. …”
Get full text

Long-term Double-J stenting is superior to short-term Single-J stenting in kidney transplantation. by Christiaan A J Oudmaijer, Kelly Muller, Erika van Straalen, Robert C Minnee, Diederik J A N Kimenai, Marlies E J Reinders, Jacqueline van de Wetering, Jan N M IJzermans, Turkan Terkivatan

“…We aim to prospectively determine the most effective stenting approach.…”
Get full text

Effect of Camel Milk on the Physicochemical, Rheological, and Sensory Qualities of Bread by Noha M. Almoraie, Israa M. Shatwan

“…Hence, it is necessary to use additional nutritional sources to maintain nutritional value. …”
Get full text

Field-Based Biochar, Pumice, and Mycorrhizae Application on Dryland Agriculture in Reducing Soil Erosion by Surya Sabda Nugraha, Junun Sartohadi, Makruf Nurudin

“…The research was conducted using a field plot during the peak of the rainy season (March-April) of 2021. …”
Get full text

The effects of nutrients on the growth and quality of medicinal and aromatic plants, affecting athletic abilities by Mohammad Miransari, Shirin Adham, Mahdiar Miransari, Amir Arshia Miransari

“…Background: Although the use of medicinal and aromatic plants (herbs and fruits) has become popular, worldwide, more has yet to be indicated on their applications, due to their significance from economic and health aspects. …”
Get full text

Genre et discours métaphoriques sur la traduction by Lori Chamberlain

“…This analysis, written during the emergence of feminist translation studies across the Atlantic, challenges a masculine and sexist conception of translation and creativity written about in terms of domination, power, gender and violence. …”
Get full text

New‐Occurrence of Postoperative Modic Changes and Its Influence on the Surgical Prognosis After Percutaneous Endoscopic Lumbar Disc Discectomy by Lei Li, Chao Wang, Hao Zhang, Zhiming Liu, Zheng Lian, Han Li, Hao Tao, Xuexiao Ma

“…Pain levels and surgical outcomes were evaluated using the visual analog scale, Oswestry Disability Index, and Macnab criteria. …”
Get full text

Effect of a multispecies probiotic on reducing the incidence of antibiotic-associated diarrhoea in children: a protocol for a randomised controlled trial by Hania Szajewska, Jan Łukasik

“…The primary outcome will be the incidence of AAD, defined as ≥3 loose or watery stools (a score of A on the Amsterdam Infant Stool Scale or a score of 5–7 on the Bristol Stool Form scale) in 24 hours, caused either by Clostridium difficile or of otherwise unexplained aetiology, occurring during the intervention period. The secondary outcomes will include the incidence of AAD according to alternative definitions; the incidence of any kind of diarrhoea; the duration of diarrhoea; the need for hospitalisation; intravenous rehydration or discontinuation of antibiotic treatment due to diarrhoea; adverse events; and the intestinal microbiota composition.Ethics and dissemination The study protocol is approved by the Ethics Committee of the Medical University of Warsaw. …”
Get full text