The SpxA1-TenA toxin-antitoxin system regulates epigenetic variations of Streptococcus pneumoniae by targeting protein synthesis. by Shaomeng Wang, Xiu-Yuan Li, Mengran Zhu, Haiteng Deng, Juanjuan Wang, Jing-Ren Zhang

“…Because spontaneous variations frequently occur during bacterial growth in the number of the AT di-nucleotides in the promoter region of the spxA1-tenA operon, this locus acts as a programmed genetic switch that generates pneumococcal subpopulations with epigenetic and phenotypic diversity.…”
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National assessment on the frequency of pain medication prescribed for intrauterine device insertion procedures within the Veterans Affairs Health Care System. by Anna D Ware, Terri L Blumke, Peter J Hoover, Zach P Veigulis, Jacqueline M Ferguson, Malvika Pillai, Thomas F Osborne

“…Despite its benefits, many patients report moderate to severe pain during and after their IUD insertion procedure. Furthermore, reports suggest significant variability in pain control medications, including no adequate pain medication. …”
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On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States by Renessa S. Williams, Acklynn M. Byamugisha, Leah Davis-Ewart, Omar R. Valentin, Samantha E. Dilworth, Christian Grov, Adam W. Carrico

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Health as the Main Value of Life in the Well-Wishes of the Mongolian peoples by Evdokia E. Khabunova, Ludmila S. Dampilova, Balzira V. Elbikova

“…The study is based on the materials identified from oral sources during the expedition work and from publications containing the texts of traditional good wishes. …”
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Immunoassay–mass spectrometry to identify Brucella melitensis by Amirreza Sharif, Ramin Bagheri Nejad, Alireza Ghassempour

“…When dealing with hazardous bacteria like Brucella, which are more difficult to handle and cure, this problem becomes even more crucial. To overcome these obstacles, Fe3O4 magnetic nanoparticles (MNPs) linked with Brucella-specific antibodies and MALDI-TOF MS analysis have been used to create a quick and accurate technique for direct bacterial separation and identification in complex samples. …”
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Enabling analytical precision in microplastic analysis: innovative solutions for precise method validation, evaluation and quality control by Jovan Badzoka, Christoph Kappacher, Jakob Lauß, Lisa Obwaller, Anna Pavun, Christian W. Huck

“…Leveraging Fourier Transform Infrared (FT-IR) and Quantum-cascade laser (QCL) imaging, we introduce a method that utilizes potassium bromide (KBr) pellets embedded with microplastics (MPs), facilitating exact particle number determination for method validation and quality control (QC) using FT-IR imaging of formed potassium bromide (KBr) pellets. …”
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Herpes Zoster after COVID-19 Infection or Vaccination: A Prospective Cohort Study in a Tertiary Dermatology Clinic by Charussri Leeyaphan, Pattriya Jirawattanadon, Sumanas Bunyaratavej, Waratchaya Panjapakkul, Thrit Hutachoke, Yanisorn Nanchaipruek, Phumithep Phumariyapong

“…HZ recurrence was reported in five cases, of which 80% had been vaccinated or infected with COVID-19 during the previous 21 days. All patients had similar durations of antiviral treatment, crust-off time, and duration of neuralgia. …”
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External Validation of the International Prognosis Prediction Model of IgA Nephropathy by Lichao Hu, Yi Fang, Jiaxin Huang, Jin Liu, Lingling Xu, Weichun He

“…Two predictive models, one inclusive and the other exclusive of a race parameter, underwent evaluation via receiver-operating characteristic (ROC) curves, subgroup survival analyses, calibration plots, and decision curve analyses.Results The median follow-up duration within our cohort spanned 5.1 years, during which 18 patients encountered the primary outcome. …”
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The Effectiveness of Modified Atkins Ketogenic Diet on Children with Intractable Epilepsy: A Pilot Study from Indonesia by Achmad Rafli, Setyo Handryastuti, Mulya Rahma Karyanti, Yoga Devaera, Cut Nurul Hafifah, Irawan Mangunatmadja, Muzal Kadim, Elisabeth Siti Herini, Lora Sri Nofi, Ariek Ratnawati, Suci Fitrianti

“…However, no study has been conducted to evaluate the use of MAD in children with severe epilepsy in Indonesia. …”
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Clinical impact of proteinuria on renal function and treatment outcomes in patients with radioiodine-refractory thyroid cancer treated with lenvatinib by Naoki Fukuda, Kazuhisa Toda, Hirotaka Suto, Ryosuke Oki, Xiaofei Wang, Tetsuya Urasaki, Yasuyoshi Sato, Kenji Nakano, Makiko Ono, Junichi Tomomatsu, Hiroki Mitani, Shunji Takahashi

“…Proteinuria has been described as a major on-target adverse event of lenvatinib, although its long-term impact on renal function and clinical outcomes remains unclear. We conducted a retrospective observational study to assess renal function and prognosis in patients with radioiodine-refractory differentiated thyroid cancer (RR-DTC) receiving lenvatinib. …”
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My child’s legacy: a mixed methods study of bereaved parents and providers’ opinions about collaboration with NICU teams in quality improvement initiatives by Annie Janvier, Sonia Dahan, Claude Julie Bourque, Ginette Mantha, Martin Reichherzer

“…All of them reported that their participation had positive impacts, but two parents also reported a reactivation of traumatic experiences during a medical simulation activity. All participants expressed a desire for further collaboration. …”
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Calves gastrointestinal nematodes and Eimeria prevalence and associated risk factors in dairy farms, southern Ethiopia by Maireg Hailu, Kassahun Asmare, Endrias Zewdu Gebremedhin, Vincenzo Di Marco Lo Presti, Maria Vitale, Desie Sheferaw

“…To this end, a flotation technique was used to recover Nematode egg and Eimeria oocyst from rectally collected faeces. …”
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Comparison of Physicians’ Perceptions Regarding Dermatological Diseases by Melek Aslan Kayıran, Hasan Aksoy

“…However, contrary to the literature, non-dermatologist physicians have expressed opinions that isotretinoin should be used as little as possible due to potential harm to the liver and that allergy tests should be performed in cases of acute urticaria. …”
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Mapping Temperature Zone of Ethiopia for Binder Performance Grading System by Mahlet G. Mihretu, Habtamu M. Zelelew

“…This approach provides a better understanding of pavement behavior during its operational phase. Despite these findings, Ethiopia’s current asphalt binder procurement process still relies on the penetration grading system, which uses a 25°C test temperature with a 100-g loading weight. …”
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Comparative Study of Periodontal Health in Patients with Fixed Braces Versus Clear Aligners by Selvakumar Annamalaisamy, B.S. Malthesh, G. M. Shashikumar, Sreedhara Shantharam, P Kiran Kumar

“…Background: Orthodontic therapy is often used to cure dental malocclusions; however, since orthodontic equipment is difficult to keep clean, it might have an adverse effect on periodontal health. …”
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Morphometric, histometric and histomorphological investigation of the effects of different ratios safflower (chartamus tinctorius l.) oil supplements on glandula uropygialis in jap... by İsmail Demircioğlu, Bestami Yılmaz, Kürşat Filikçi, Gülşah Güngören, Faruk Bozkaya

“…<p> <b>Conclusion:</b> As a result we suggested that safflower oil which is effective on lipid metabolism had significant impacts on the morphometric parameters of glandula uropygialis in Japanese quails. …”
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Delirium Management Quality Improvement Project to Improve Awareness and Screening in a Medical ICU by Hirsh Makhija, Kyle Digrande, Omar Awan, Russell G. Buhr, Rajan Saggar, Victoria Ramirez, Rainbow Tarumoto, Janelle M. Fine, Atul Malhotra, Dale M. Needham, Jennifer L. Martin, Biren B. Kamdar

“…<b>Background/Objectives:</b> Although delirium is common during critical illness, standard-of-care detection and prevention practices in real-world intensive care unit (ICU) settings remain inconsistent, often due to a lack of provider education. …”
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Biomechanical Modeling and Evaluation of Buttocks Automatic Assisted Repositioning in Bedridden Patients by Liqing Yang, Ganjun Song, Di Luo, Haotian Xu, Jiamei Han, Mingzhao Xiao, Dingqun Bai, Shan Tian, Wensheng Hou, Jisi Tang, Xin Zhang, Lin Chen

“…However, the lack of effective models to elucidate the mechanical responses of deep tissue during assisted repositioning and identify the optimal tilt angle has hindered the implementation of effective automatic assisted repositioning systems for long-term care patients. …”
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Prevalence and Associated Risk Factors of Childhood Obesity and Overweight in Erbil City, Kurdistan, Iraq: A Household Survey by Sabah Shareef Mohammed, Sherzad Abdulahad Shabu

“… The prevalence of overweight and obesity has increased dramatically during the last three decades. It is estimated that 170 million youngsters (under the age of 18) worldwide are overweight. …”
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PretoxTM: a text mining system for extracting treatment-related findings from preclinical toxicology reports by Javier Corvi, Nicolás Díaz-Roussel, José M. Fernández, Francesco Ronzano, Emilio Centeno, Pablo Accuosto, Celine Ibrahim, Shoji Asakura, Frank Bringezu, Mirjam Fröhlicher, Annika Kreuchwig, Yoko Nogami, Jeong Rih, Raul Rodriguez-Esteban, Nicolas Sajot, Joerg Wichard, Heng-Yi Michael Wu, Philip Drew, Thomas Steger-Hartmann, Alfonso Valencia, Laura I. Furlong, Salvador Capella-Gutierrez

“…Scientific Contribution While text mining solutions have been widely used in the clinical domain to identify adverse drug reactions from various sources, no similar systems exist for identifying adverse events in animal models during preclinical testing. …”
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