Gut bacteria Prevotellaceae related lithocholic acid metabolism promotes colonic inflammation by Liping Chen, Zhenghao Ye, Junhua Li, Lijia Wang, Yu Chen, Meiping Yu, Jian Han, Jiangeng Huang, Dongyan Li, Yongling Lv, Kai Xiong, De’an Tian, Jiazhi Liao, Ursula Seidler, Fang Xiao

“…Histological analysis, quantitative PCR (qPCR) and Western Blotting were conducted on colonic samples from DSS-induced colitis mice to assess colonic inflammation, mucosal barrier integrity, and associated signaling pathways. …”
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Preindustrial-to-present-day changes in atmospheric carbon monoxide: agreement and gaps between ice archives and global model reconstructions by X. Faïn, S. Szopa, V. Naïk, P. Martinerie, D. M. Etheridge, D. M. Etheridge, R. H. Rhodes, C. M. Trudinger, C. M. Trudinger, V. V. Petrenko, K. Fourteau, P. Place, P. Place

“…Over the 1980–2010 CE period (common era; all subsequent years in the paper are reported in CE), trends in ice archive and firn air observations and AerChemMIP outputs align remarkably well at northern and southern high latitudes, indicating improved quantification of anthropogenic CO emissions and the main CO sink (OH oxidation) compared to ACCMIP. …”
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Characterisation of pregnancy-induced alterations in apolipoproteins and their associations with maternal metabolic risk factors and offspring birth outcomes: a preconception and l... by Li Chen, Karen Mei-Ling Tan, Melvin Khee-Shing Leow, Kok Hian Tan, Jerry Kok Yen Chan, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Markus R. Wenk, Sartaj Ahmad Mir

“…However, there is a lack of longitudinal studies to quantify the concentrations of maternal apolipoproteins from preconception to postpartum and their associations with maternal metabolic health and offspring birth outcomes. Methods: Quantification of apolipoproteins was performed on maternal plasma samples (N = 243 trios) collected at preconception, 26–28 weeks’ pregnancy, and three months postpartum in the Singapore PREconception Study of long-Term maternal and child Outcomes (S-PRESTO) cohort study. …”
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Liver damage in patients living with HIV on antiretroviral treatment with normal baseline liver function and without HBV/HCV infection: an 11-year retrospective cohort study in Gua... by Jun Yu, Hao Liang, Fengxiang Qin, Junjun Jiang, Chunwei Qin, Yunxuan Huang, Bingyu Liang, Yuexiang Xu, Jiegang Huang, Zhiliang Xu, Chuanyi Ning, Yanyan Liao, Ning Zang, Jingzhen Lai, Wudi Wei, Li Ye, Xionglin Qin

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Upper Oligocene to Pleistocene planktonic foraminifera stratigraphy at North Atlantic DSDP Site 407, Reykjanes Ridge: diversity trends and biozonation using modern Neogene taxonomi... by T. M. Weitkamp, T. M. Weitkamp, M. J. Razmjooei, M. J. Razmjooei, P. N. Pearson, H. K. Coxall, H. K. Coxall

“…Systematic species counts enable quantitative diversity analysis, with a particular focus on the genus <i>Neogloboquadrina</i>, which becomes increasingly prevalent at Site 407 from the late Neogene to Quaternary. …”
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Regulatory role of lnc-MAP3K13-3:1 on miR-6894-3p and SHROOM2 in modulating cellular dynamics in hepatocellular carcinoma by Kuai Chen, Manqin Zhu, Qinghua Hu, Hui Huang, Ka Chen, Xia Shuai, Jinshi Huang, Qiang Tao, Zhibin Guo

“…Objective This study aimed to investigate the role of lnc-MAP3K13-3:1 in regulating miR-6894-3p, with a focus on its impact on proliferation, apoptosis, migration, and related cellular processes in liver cancer cells via SHROOM2 regulation. Methods Quantitative PCR (qPCR) was initially employed to measure the expression levels of lnc-MAP3K13-3:1 and miR-6894-3p in three HCC cell lines: HepG2, HuH-7, and Li-7. …”
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Influence of Socio-Demographic, Occupational and Lifestyle Variables on Sleep Time by Dutheil F, Saint-Arroman C, Clinchamps M, Flaudias V, Fantini ML, Pereira B, Berthon M, Laporte C, Baker JS, Charkhabi M, Cocco P, Lecca R, Puligheddu M, Figorilli M, Zak M, Ugbolue UC, Ubago-Guisado E, Gracia-Marco L, Bouillon-Minois JB, Vialatte L

“…Total sleep time was evaluated using declared bedtime and time of awakening and was analyzed as a quantitative variable and as a qualitative variable.Results: We included 549 respondents to the questionnaire, divided into 10-year age groups ranging from < 30yo to ≥ 60yo. …”
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The role of smell in medical and psychological disorders: An interdisciplinary approach by Giuseppe Riva

“…In 2017, the position paper by Hummel et al. on olfactory dysfunction gave the definitions of qualitative and quantitative smell impairments [1]. Hyposmia is a reduced ability to detect odors, anosmia is the complete inability to detect odors, parosmia is a change in the normal perception of odors, such as when the smell of something familiar is distorted, or when something that normally smells pleasant now smells foul. …”

A Study on the Yield Stability of Oilseed Sunflower Genotypes under Drought Stress by Nasrin Akbari, Reza Darvishzadeh

“…Therefore, taking into account the quantitative control, and the effects of the environment and the interaction of the genotype × environment, selection for this trait is complex, costly, and time-consuming. …”
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ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation by Li-Quan Huang, Ting-Xuan Yan, Bao-Sheng Wang, Hao Li, Nai-Bao Zhou

“…Methods: To evaluate the expression of ZC3H15 in cancer-induced pain, we used microcomputed tomography (MicroCT), immunoblotting, co-immunoprecipitation (Co-IP), behavior tests, quantitative real-time polymerase chain reaction (qRT-PCR), and immunofluorescence assays in this investigation. …”
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Impact of periodontal microRNAs associated with alveolar bone remodeling during orthodontic tooth movement: a randomized clinical trial by Alessandro Polizzi, Angela Alibrandi, Antonino Lo Giudice, Alfio Distefano, Laura Orlando, Amer M. Analazi, Giuseppe Pizzo, Giovanni Li Volti, Gaetano Isola

“…Clinical parameters and gingival crevicular fluid (GCF) sampling were performed on both compression and tension sides of a random canine to be distalized (test groups) at baseline and at 1 h, 1 day, 1 month and at 3-month after OTM, while the contralateral canine served as a control group. miRNAs − 7a-3p, -7a-2-3p, -7a-5p, -21-3p, -21-5p, -100-3p, -100-5p, -125b-2-3p, -125b-5p, -200b-3p, and − 200b-5p expression was analyzed using a real-time quantitative polymerase chain reaction (RT-PCR). Data were analyzed to assess miRNAs change following OTM. …”
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Effect of lncRNA H19 on Rats with Chronic Heart Failure Based on TGF-β1/Smad3 Signaling Pathway by WANG Lingyan, CAO Guojun, MEI Yang, ZHANG Bin, ZHOU Shijing

“…Two days after the last injection, color Doppler ultrasound was used to detect cardiac function indexes [left ventricular ejection fraction (LVEF), left ventricular fractional shortening (LVFS), left ventricular end-systolic dimension (LVESD), left ventricular end-diastolic dimension (LVEDD)]; Masson staining was used to detect myocardial fibrosis and collagen volume fraction (CVF); real-time fluorescence quantitative PCR was used to detect the transcription level of lncRNA H19 and miRNA-200a in myocardial tissue of rats; Western blot method was used to detect the protein expression level of TGF-β1 and Smad3 in myocardial tissue of rats.ResultsCompared with sham surgery group, the protein expression level of LVEDD, LVESD, TGF-β1, Smad3 and transcription level of miRNA-200a in the other four groups significantly increased, while the protein expression level of LVFS, LVEF and transcription level of lncRNA H19 significantly decreased (<italic>P</italic>&lt;0.05); compared with the heart failure group and the negative control group, the protein expression level of LVEDD, LVESD, TGF-β1, Smad3 and transcription level of miRNA-200a in the overexpression group and the combined overexpression group significantly decreased, while the protein expression level of LVFS, LVEF and transcription level of lncRNA H19 significantly increased (<italic>P</italic>&lt;0.05); compared with the overexpression group, the protein expression level of LVEDD, LVESD, TGF-β1, Smad3 and transcription level of miRNA-200a in the combined overexpression group significantly increased, while LVFS and LVEF significantly decreased (<italic>P</italic>&lt;0.05), and the transcription level of lncRNA H19 was not statistically different (<italic>P</italic>&gt;0.05). …”
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Bilateral Virtual Water Trade Balance and Sustainable Development using the Gravity Model An Explanation by sepideh ameri golestan, sadegh bakhtiari, Sara Ghobadi

“…In general, it is considered a virtual water exporter. The existence of quantitative and qualitative problems in the country’s water resources and the location of Iran in an arid and semi-arid region and facing water shortage crises, is necessary to pay attention to the demand for water at the macro level and formulate basic plans for the sustainable use of water resources. …”
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FTO rs17817449 Variant Increases the Risk of Severe Obesity in a Brazilian Cohort: A Case-Control Study by Salum KCR, Assis ISS, Kopke ÚA, Palhinha L, Abreu GM, Gouvêa LW, Teixeira MR, Mattos FCC, Nogueira Neto JF, Felício RFM, Rosado EL, Zembrzuski VM, Campos Junior M, Maya-Monteiro CM, Cabello PH, Carneiro JRI, Bozza PT, Kohlrausch FB, da Fonseca ACP

“…We collected demographic, body composition, biochemical, and genotyping data by real-time PCR, and performed logistic and linear regression analyses to investigate the association of polymorphisms with severe obesity status and obesity-related quantitative parameters.Results: Individuals with severe obesity had significantly higher anthropometric measures, blood pressure, and biochemical levels. …”
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Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis by Samuel R. Moen, Jeffrey R. Misialek, Timothy M. Hughes, Craig W. Johnson, Mark J. Sarnak, Sarah N. Forrester, W.T. Longstreth, Jr., Mercedes R. Carnethon, James S. Pankow, Sanaz Sedaghat

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Intimate partner violence among women of reproductive age during the COVID-19 pandemic in Ethiopia: a systematic review and meta-analysis by Gizachew Yilak, Alemayehu Sayih Belay, Aychew Kassie, Befkad Derese Tilahun, Ambaw Abebaw Emrie, Mulat Ayele, Eyob Shitie Lake, Legese Fekede Abza

“…Therefore, this study aimed to assess the pooled prevalence of IPV and its determinants among women of reproductive age during the COVID-19 pandemic in Ethiopia.Design Systematic review and meta-analysis.Data sources The review was done as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline using different search databases such as: PubMed/Medline, Cochrane Library, Virtual Health Library Regional Portal, HINARI (research4life), and Google Scholar.Eligibility criteria Those quantitative studies conducted in Ethiopia during the COVID-19 pandemic, that reported the prevalence of IPV among women of reproductive age, and were published in English from 13 March 2020 to 15 October 2025, were included for this study.Data extraction and synthesis All authors independently extracted data using the Joanna Briggs Institute manual for evidence synthesis. …”
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Relationship between changes in the triglyceride glucose-body mass index and frail development trajectory and incidence in middle-aged and elderly individuals: a national cohort st... by Kai Guo, Qi Wang, Lin Zhang, Rui Qiao, Yujia Huo, Lipeng Jing, Xiaowan Wang, Zixuan Song, Siyu Li, Jinming Zhang, Yanfang Yang, Jinli Mahe, Zhengran Liu

“…Nonlinear relationships were explored using restricted cubic splines, and a linear mixed-effects model was used to evaluate FI development speed. Weighted quantile regression was used to identify the primary contributing factors. …”
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Prevailing Antibiotic Resistance Patterns in Hospitalized Patients with Urinary Tract Infections in a Vietnamese Teaching Hospital (2014 &ndash; 2021) by Le HHL, Thuc LC, Ta TB, Tran TV, Hung DV, Kien HT, Le MN, Luong VH, Nguyen VTH, Pham HQ, Le HV, Viet NH, Hoang LH, Nguyen TT, Latsavong M, Le TD, Trong Tuan D, An NV

“…Hai Ha Long Le,1,2 Luong Cong Thuc,3 Thang Ba Ta,4 Tien Viet Tran,5 Dinh Viet Hung,6 Hoang Trung Kien,7 Minh Nhat Le,8,9 Vu Huy Luong,10,11 Vinh Thi Ha Nguyen,11,12 Hoa Quynh Pham,13 Hung Van Le,11,13 Nguyen Hoang Viet,14 Le Huy Hoang,15 Tram Thuy Nguyen,15 Mixay Latsavong,16 Tuan Dinh Le,17 Dao Trong Tuan,18 Nguyen Van An19 1Department of Clinical Microbiology and Parasitology, Faculty of Medical Technology, Hanoi Medical University, Hanoi, Vietnam; 2Department of Biochemistry, Hematology and Immunology, National Hospital of Dermatology and Venereology, Hanoi, Vietnam; 3Cardiovascular Center, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam; 4Respiratory Center, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam; 5Department of Infectious Diseases, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam; 6Department of Psychiatry, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam; 7Department of Immunology, Vietnam Military Medical University, Hanoi, Vietnam; 8Tay Nguyen Institute of Science Research, Vietnam Academy of Science and Technology, VAST, Hanoi, Vietnam; 9Antimicrobial Resistance Research Center, National Institute of Infectious Disease, Tokyo, Japan; 10Department of Laser and Skincare, National Hospital of Dermatology and Venereology, Hanoi, Vietnam; 11Department of Dermatology and Venereology, Hanoi Medical University, Hanoi, Vietnam; 12Department of General Planning, National Hospital of Dermatology and Venereology, Hanoi, Vietnam; 13Department of Microbiology, Mycology and Parasitology, National Hospital of Dermatology and Venereology, Hanoi, Vietnam; 14Molecular Pathology Department, Faculty of Medical Technology, Hanoi Medical University, Hanoi, Vietnam; 15Department of Bacteriology, National of Hygiene and Epidemiology, Hanoi, Vietnam; 16Department of Nephrology-Hemodialysis, Military Central Hospital 103, Vientiane, Laos; 17Department of Rheumatology and Endocrinology, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam; 18ENT Department, Central Military Hospital 108, Hanoi, Vietnam; 19Department of Microbiology, Military Hospital 103, Vietnam Military Medical University, Hanoi, VietnamCorrespondence: Nguyen Van An, Department of Microbiology, Military Hospital 103, Vietnam Military Medical University, Hanoi, 100000, Vietnam, Tel + 84 982 860 055, Email ank59hvqy@gmail.comPurpose: In a Vietnamese teaching hospital, this study examined the prevalence and patterns of antimicrobial resistance (AMR) of common bacteria isolated from hospitalized patients with urinary tract infections (UTIs) between 2014 and 2021.Methods: From 4060 urine samples collected, common pathogens were isolated using quantitative culture on brilliance UTI Clarity agar and blood agar. …”
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Student Engagement and Feedback on Online Learning and Facilitation: A Case Study of the National Open University of Nigeria by Adewale Adesina, Dorothy Ofoha, Olufemi A. Peters, Isaac S. Butswat

“…Des statistiques descriptives ont été utilisées pour analyser les données quantitatives, tandis qu'une approche d'analyse thématique a été appliquée pour examiner les réponses aux questions ouvertes de l'enquête. …”
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The sense of safety theoretical framework: a trauma-informed and healing-oriented approach for whole person care by Johanna M. Lynch, Kurt C. Stange, Christopher Dowrick, Linn Getz, Pamela J. Meredith, Mieke L. Van Driel, Meredith G. Harris, Meredith G. Harris, Kate Tillack, Caley Tapp, Caley Tapp

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