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14021
Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis
Published 2025-01-01“…Meta-regression and bias assessment were performed.Results Out of 20 100 records identified, 37 studies (including 2 564 189 individuals) from 22 countries were included in the qualitative synthesis and the quantitative meta-analysis. In most countries, the annual cost of CHD exceeds many times the total health expenditure per capita. …”
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14022
Alterations in the polarization of liver M1/M2 macrophages upon long-term administration of triptorelin in rats
Published 2024-11-01“…The long-term administration of triptorelin causes changes in quantitative and qualitative modifications of the macrophage population. …”
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14023
A phase Ia study of a novel anti-HER2 antibody–drug conjugate GQ1001 in patients with previously treated HER2 positive advanced solid tumors
Published 2025-01-01“…The plasma concentration of free DM1, the payload of GQ1001, was quantitated. Results A total of 32 patients were enrolled, predominantly in breast (9), gastric or gastro-esophageal junction (9) and salivary gland cancer (4). …”
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14024
LINC01089 governs the miR-1287-5p/HSPA4 axis to negatively regulate osteogenic differentiation of mesenchymal stem cells
Published 2024-12-01“…In this study, we aimed to disclose how LINC01089 functions in human mesenchymal stem cell (hMSC) osteogenic differentiation, and to study the mechanism by which LINC01089 regulates MSC osteogenesis. Methods: Quantitative reverse transcription polymerase chain reaction (RT-qPCR) and western blotting were performed to analyze LINC01089, miR-1287-5p, and heat shock protein family A (HSP70) member 4 (HSPA4) expression. …”
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14025
Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus
Published 2025-02-01“…Methods We conducted a proteomic analysis of PBMCs from patients with T1DM and relapsing remitting Multiple Sclerosis (herein forth MS) patients (n = 9 per condition), using a label-free quantitative proteomics approach. The patients were diagnosed following the American Diabetes Association (ADA) criteria for T1DM and McDonald criteria for MS respectively, and were aged over 18 years and more than 2 years from the onset respectively. …”
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14026
Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat
Published 2025-01-01“…Social play behavior was evaluated at PN40. The quantification and morphology of microglia in the NAc were measured on PN30. …”
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14027
Confocal Microscopy for Detection of Intracellular Bacteria in Urine Samples of patients Suspected with Urinary Tract Infection: A Cross-sectional Observational Study
Published 2025-02-01“…Formation of biofilm ability was assessed by tube method. Quantitative data presented as mean and Standard Deviation (SD) while qualitative variables expressed as frequency (percentage). …”
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14028
Deciphering hub genes and immune landscapes related to neutrophil extracellular traps in rheumatoid arthritis: insights from integrated bioinformatics analyses and experiments
Published 2025-01-01“…We further investigated hub gene expression using immunohistochemistry (IHC) in an adjuvant-induced arthritis rat model and real-time quantitative polymerase chain reaction (RT-qPCR) in a clinical cohort.ResultsSeven cellular subpopulations were identified through downscaling and clustering, with neutrophils likely the most crucial cell clusters in RA. …”
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14029
Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients
Published 2019-01-01“…Biochemical assessment, viral load quantitation, and HBV markers were tested. Chinese medicine symptom complex score was evaluated and recorded as well. …”
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14030
Interferon (IFN)-gamma (γ) inducible protein 10 (IP-10) in the diagnosis of latent and active tuberculosis in Bacille Calmette Guerin (BCG)-vaccinated pediatric population.
Published 2025-01-01“…The research specifically assessed IP-10 levels in serum, urine, and QuantiFERON-TB Gold Plus (QFT) cultures stimulated with M.tb antigens to determine if IP-10 could be a useful diagnostic marker for pediatric tuberculosis, either alongside or as an alternative to IFN-γ.…”
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14031
The Collections of Miraculous Stories on the Buddhāvataṃsaka-sūtra
Published 2025-01-01“…This paper reviews nine key collections associated with the Huayan jing, including: Record of the Transmission of the Avataṃsaka-sūtra (Huayanjing Zhuanji 華嚴經傳記), Account of Stimuli and Responses Related to the Avataṃsaka-sūtra (Dafangguang fo huayanjing ganying zhuan 大方廣佛華嚴經感應傳), Account of the Search for the Profundities of the Avataṃsaka-sūtra (Huayanjing tanxuan ji 華嚴經探玄記), Commentary on the Avataṃsaka-sūtra (Dafangguang fo huayanjing shu 大方廣佛華嚴經疏), Sub-commentary on the Avataṃsaka-sūtra (Dafangguang fo huayan sui shu yanyi chao 大方廣佛華嚴經隨疏演義抄), Account of Chengguan’s Commentary on the Avataṃsaka-sūtra (Huayan xuantan huixuan ji 華嚴懸談會玄記), Short Record of Accounts of Stimuli and Responses Related to the Avataṃsaka-sūtra (Dafangguang fo huayanjing ganying lüeji 大方廣佛華嚴經感應略記), and Causes of Stimuli and Response Related to the Avataṃsaka-sūtra (Huayanjing ganying yuanqi zhuan 華嚴經感應緣起傳), as well as the Chronological Account of the Efficacies of the Avataṃsaka-sūtra (Lichao huayanjing chiyan ji 歷朝華 嚴經持驗紀). …”
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14032
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14033
Association of pituitary neuroendocrine tumors and neurofibromatosis type 1: assessing causation versus coincidence. Case report
Published 2025-02-01“…NF1 expression was analyzed via quantitative polymerase chain reaction (qPCR) in blood and tumor cDNA. …”
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14034
Leveraging machine learning to uncover multi-pathogen infection dynamics across co-distributed frog families
Published 2025-01-01“…We screened and quantified infection loads via quantitative PCR for three major pathogens: the fungal pathogen Batrachochytrium dendrobatidis (Bd), double-stranded viruses in the lineage Ranavirus (Rv), and the alveolate parasite currently referred to as Amphibian Perkinsea (Pr). …”
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14035
Narratives of swiss football players about talent - and positive youth development: The role of social agents and agency.
Published 2025-01-01“…Methods This study builds on a longitudinal quantitative investigation that tracked 109 Swiss elite youth football players born in 1999 throughout their developmental journeys. …”
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14036
Gender Incidence in the Salary of Informal Workers for the Management of Socioeconomic Strategies
Published 2021-08-01“…The main objective was to analyze the influence that gender has on wages of women in this sector, to establish strategies that can promote more equitable development. Qualitative and quantitative approaches were used using inductive and deductive methods. …”
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14037
Impact of pediatric tracheostomy on family caregivers’ burden and quality of life: a systematic review and meta-analysis
Published 2025-01-01“…We undertook a systematic review and meta-analysis to determine the impact of pediatric tracheostomy on caregivers’ QOL and caregiver burden.MethodsWe performed a search for quantitative studies measuring QOL, caregiver burden and related factors such as psychological distress, coping, stress, and financial strain using validated instruments, reported by caregivers of children with tracheostomy. …”
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14038
Factors associated with caffeine intake among undergraduates: a cross-sectional study from Palestine
Published 2025-02-01“…Caffeine consumption was assessed using a semi-quantitative food frequency questionnaire (FFQ) developed by the research team. …”
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14039
Translation and assessment of encultured meaning of the Multi-Dimensional Scale of Perceived Social Support in Diné bizaad (Navajo) using community-based participatory actio...
Published 2025-01-01“…Next steps for the tool should include quantitative reliability and validity analyses. …”
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14040
Evaluating Impact of Surgical Myocardial Revascularization on Global Left Ventricular Systolic Function and Immediate Postoperative Outcome using Transesophageal Echocardiography
Published 2024-12-01“…Comparison of LV fractional shortening (LV-FS), fractional area change (LV-FAC), ejection fraction (LV-EF), indexed LV volumes (indexed LV volumes at end diastole, LV volumes at end systole) and ‘Tei’ (Myocardial performance) index obtained prior and after surgical myocardial revascularization was done for quantitative analysis. Also, the determinants of immediate postoperative outcome were evaluated based on need of pharmacological and/or mechanical cardiovascular support, mechanical ventilation, intensive care unit (ICU) stay, morbidity and mortality in immediate postoperative period. …”
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