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10381
Use of Go-Beyond as a Self-Directed Internet-Based Program Supporting Veterans’ Transition to Civilian Life: Preliminary Usability Study
Published 2025-01-01“…Users were then automatically allocated to Go-Beyond modules that aligned with their M-CARM profile. Additionally, quantitative and qualitative data were collected from a survey on aesthetics, interactivity, user journey, and user experience, which was optional for users to complete at the end of each module. …”
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10382
Phytochemical and Bioactivity Evaluation of Bee Pollen and Androecia of <i>Castanea</i>, <i>Salix</i>, and <i>Quercus</i> Species
Published 2024-12-01“…Qualitative and quantitative differences in the chemical composition between bee pollen originated from <i>Castanea sativa</i> (Türkiye and Slovenia), <i>Salix</i> spp. …”
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10383
Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease
Published 2025-02-01“…Finally, candidate genes were validated in ferroptosis models using reverse transcription quantitative PCR (RT-qPCR) and immunofluorescence methods.Results: Bulk RNA-seq analysis identified SLC11A1, an inflammatory gene associated with AD. …”
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10384
Development of an Integrated Model of Planning and Management in Free Zones with an Emphasis on Environmental Pressures
Published 2024-03-01“…Data collection was conducted through both qualitative (library research) and quantitative (a researcher-designed questionnaire) methods, while data analysis utilized SPSS version 23 and Topsis Fuzzy techniques. …”
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10385
Probiotic potential and safety properties of Limosilactobacillus fermentum A51 with high exopolysaccharide production
Published 2025-01-01“…These probiotic genes were verified by quantitative real-time PCR. In vitro assays confirmed that L. fermentum A51 showed good tolerance to simulated gastrointestinal tract (8.49 log CFU/mL), 0.3% bile salt (39.06%), and possessed adhesion (86.92%), antioxidant (70.60–89.71%), and antimicrobial activities, as well as EPS and signaling molecule AI-2 synthesis capacities.ConclusionCollectively, our findings have confirmed that L. fermentum A51 is safe and exhibits good probiotic properties, thus recommending its potential application in the production of value-added fermented dairy products.…”
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10386
A case-control genome-wide association study of estimated breeding values for resistance to gastrointestinal nematodes in two local dairy sheep breeds
Published 2025-02-01“…A genome-wide case-control analysis was performed retaining the most significant single nucleotide polymorphisms (SNPs) with a threshold of 0.005% for the false discovery rate. Genes and Quantitative Trait Loci overlapping significant SNPs were annotated and enriched respectively while genes have been also enriched for functional pathways. …”
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10387
Growth of microbes in competitive lifestyles promotes increased ARGs in soil microbiota: insights based on genetic traits
Published 2025-01-01“…Paired with shot-gun metagenomics analysis and quantification of bacterial growth, trait-based assessment of soil microbiota was applied to reveal the association between key ARG subtypes, representative bacterial taxa, and functional-gene features that drive the growth of ARGs. …”
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10388
Accurate phenotype-to-genotype mapping of high-diversity yeast libraries by heat-shock-electroporation (HEEL)
Published 2025-02-01“…This design allows for robust identification and quantification of unique genotypes within a heterogeneous population using standard Sanger sequencing. …”
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10389
Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus
Published 2025-01-01“…Eight cytochrome P450 genes were analyzed for the expression level using quantitative real time-PCR. The cDNA of mosquitoes was amplified and sequenced for four fragments of vgsc gene. …”
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10390
Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3
Published 2025-02-01“…The fruit body of edible and tasty Astraeus asiaticus mushroom was extracted in ethyl acetate solvent (EA) and quantitative analysis revealed that it contained a significant amount of total phenols, flavonoids, and ascorbic acids. …”
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10391
Biofloc technology significantly reshapes water microbiome and improves survival rates in Japanese eel (Anguilla japonica)
Published 2025-02-01“…In this study, we observed the survival and growth rates of eels treated with BFT over 8 weeks and monitored changes in the gut and water microbiome using 16S rRNA amplicon sequencing (metabarcoding) and quantitative PCR. Our research demonstrated that BFT treatment was more advantageous for eel growth compared with FTS in terms of eel survival rate, feed intake amount, and growth rate. …”
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10392
Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma
Published 2023-01-01“…Here, we tested the efficacy of our novel H84T CAR in models of pancreatic ductal adenocarcinoma (PDAC), intractable tumors with aberrant glycosylation and characterized by desmoplastic stroma largely contributed by pancreatic stellate cells (PSCs).Methods We transduced human T cells with a second-generation retroviral construct expressing the H84T BanLec chimeric receptor, measured T-cell expansion, characterized T-cell phenotype, and tested their efficacy against PDAC tumor cells lines by flow cytometry quantification. In three-dimensional (3D) spheroid models, we measured H84T CAR T-cell disruption of PSC architecture, and T-cell infiltration by live imaging. …”
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10393
Mycobiome analyses of critically ill COVID-19 patients
Published 2025-02-01“…Respiratory mycobiome was profiled using internal transcribed spacer 1 sequencing, and Aspergillus fumigatus burden was further validated using quantitative PCR. Fungal communities were investigated using alpha diversity, beta diversity, taxa predominance, and taxa abundances. …”
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10394
Bases cérébrales de la motivation chez le singe rhésus : études pharmacologiques et neurophysiologiques
Published 2015-03-01“…Que ce soit en termes de choix entre plusieurs actions ou de quantité d’énergie dépensée pour une action donnée, les comportements du rapport entre les bénéfices attendus et les coûts escomptés. …”
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10395
Metal mixtures exposure with risk of elevated serum neurofilament light chain concentrations in U.S. general adults, NHANES 2013–2014
Published 2025-01-01“…We employed a two-pronged approach, combining weighted quantile sum (WQS) and Bayesian kernel machine regression (BKMR) models, to examine the association between the multiple-metals effect and sNfL concentrations. …”
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10396
Ethyl Acetate Extract of <i>Cichorium glandulosum</i> Activates the P21/Nrf2/HO-1 Pathway to Alleviate Oxidative Stress in a Mouse Model of Alcoholic Liver Disease
Published 2025-01-01“…Transcriptomic and network pharmacology analyses identified key genes and pathways, validated by reverse transcription quantitative polymerase chain reaction (RT-qPCR) and Western blotting. …”
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10397
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10398
LEGAL AND ECONOMIC PRINCIPLES OF THE FOREIGN POLICY OF INDEPENDENT AZERBAIJAN IN RELATION TO NEIGHBORING COUNTRIES
Published 2024-12-01“…The analysis determined the quantitative characteristics of the economic and legal principles of the foreign policy of independent Azerbaijan in relation to the neighbouring countries as a social phenomenon. …”
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10399
Genetic Insights Into Lipid Traits and Lipid-Modifying Drug Targets in Pregnancy Complications: A Two-Sample Mendelian Randomization Study
Published 2025-01-01“…Significant drug targets underwent further analysis using Expression Quantitative Trait Loci data, and mediation analysis identified potential mediators.Results: Increased high-density lipoprotein cholesterol (HDL-C) reduced the incidence of preeclampsia (OR: 0.755, 95% CI: 0.639– 0.891, p=0.001, FDR=0.012) and gestational diabetes mellitus (GDM) (OR: 0.835, 95% CI: 0.741– 0.942, p=0.003, FDR=0.018). …”
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10400
Identification of QTL for Plant Height Traits in Single-segment Substitution Lines of Wild Rice
Published 2024-11-01“…【Conclusion】Plant height is a quantitative trait controlled by multiple genes in rice. …”
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