Hepatokine leukocyte cell‐derived chemotaxin 2 as a biomarker of insulin resistance, liver enzymes, and metabolic dysfunction‐associated steatotic liver disease in the general popu... by Keita Suzuki, Hiromasa Tsujiguchi, Akinori Hara, Yumie Takeshita, Hisanori Goto, Yujiro Nakano, Reina Yamamoto, Hiroaki Takayama, Atsushi Tajima, Tatsuya Yamashita, Masao Honda, Hiroyuki Nakamura, Toshinari Takamura

“…Higher LECT2 levels positively correlated with homeostatic model assessment for insulin resistance (HOMA‐IR) values and negatively correlated with the quantitative insulin sensitivity check index (QUICKI) among all participants (HOMA‐IR; non‐standardized β (B) = 6.38, P < 0.01: QUICKI; B = −161, P < 0.01). …”
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Kefir Prevents Adipose Tissue Growth Through the Induction of Apoptotic Elements in High-Fructose Corn Syrup-Fed Rats by Esra Aslan, Gokhan Sadi, Hilal Guzel, Cigdem Karaca, Omer Adil Korkmaz, Mine Kanat Pektas, Mehmet Celegen, Tugce Aladag, Seyma Oncu, Mehmet Bilgehan Pektas

“…Gene expressions were evaluated with semi-quantitative real-time polymerase chain reaction (qRT-PCR). …”
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Genetic Variants Flanking the FGF21 Gene Were Associated with Renal Function in Chinese Patients with Type 2 Diabetes by Weihui Yu, Hong Zhu, Xiong Chen, Xuejiang Gu, Xingxing Zhang, Feixia Shen, Weiping Jia, Cheng Hu

“…The association between these SNPs and DKD as well as DKD-related quantitative traits was analyzed. Results. We did not find any significant association between these SNPs and susceptibility to DKD in the present study. …”
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Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer by Tilo Wuensch, Jonas Wizenty, Janina Quint, Wolfgang Spitz, Madeleen Bosma, Olaf Becker, Andreas Adler, Wilfried Veltzke-Schlieker, Martin Stockmann, Sascha Weiss, Matthias Biebl, Johann Pratschke, Felix Aigner

“…Gene expression was determined by quantitative real-time PCR. In addition, FNDC expression data from publicly available Gene Expression Omnibus (GEO) data sets (GDS4296, GDS4515, and GDS5232) were analyzed. …”
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Associations between exposure to volatile organic compounds with obesity in adults by Runmiao Wu, Lei Jia, Xu Zhu, Gongchang Guan, Junkui Wang, Rutai Hui, Meijuan Ma, Zhao Zhao, Hui Pang, Ling Zhu

“…Linear regression and logistic regression models were employed to estimate β-coefficients or odds ratios (ORs) along with their corresponding 95 % confidence intervals (CIs). Quantile g-computation (Qgcomp) regression, a method designed to evaluate the combined effects of multiple correlated chemical exposures, was used to assess the mixed influence of VOC metabolites on obesity-related outcomes. …”
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Los olvidados: Non-BRCA variants associated with Hereditary breast cancer in Mexican population by Dione Aguilar, María Lourdes Garza-Rodríguez, Carolina Elizabeth Muñiz-Garza, Fernando Alcorta Nuñez, Cynthia Mayte Villarreal-Garza, Oscar Vidal-Gutiérrez, Diana Cristina Pérez-Ibave, Carlos Horacio Burciaga-Flores

“…For the data analysis of qualitative and quantitative variants, JASP statistical software (version 0.18.1) was used, taking p < 0.05 as a significant result. …”
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Comparative Sensitivity of MRI Indices for Myelin Assessment in Spinal Cord Regions by Philip Kyeremeh Jnr Oppong, Hiroyuki Hamaguchi, Maho Kitagawa, Nina Patzke, Kevin C. Wakeman, Khin Khin Tha

“…<b>Methods:</b> MRI was performed on a deer’s ex vivo cervical spinal cord. Quantitative indices known to be sensitive to myelin, including the myelin water fraction (MWF), magnetization transfer ratio (MTR), the signal ratio between T1- and T2-weighted images (T1W/T2W), fractional anisotropy (FA), mean diffusivity (MD), electrical conductivity (σ), and T1, T2, and T1ρ relaxation times were calculated. …”
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A novel multimodality anthropomorphic phantom enhances compliance with quality assurance guidelines for magnetic resonance imaging in radiotherapy by Meshal Alzahrani, David A Broadbent, Irvin Teh, Bashar Al-Qaisieh, Emily Johnstone, Richard Speight

“…In MRI-CT registration, no errors were found; the ACR phantom offered more quantitative landmarks, while the anthropomorphic phantom provided limited structures. …”
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Oligogenic effect is associated with the clinical heterogeneity of autosomal dominant deafness-15 by Jianyan Pan, Hua Teng, Fang Liu, Siyi Chen, Yaning Liu, Yanling Teng, Desheng Liang, Zhuo Li, Lingqian Wu

“…By using the real time quantitative PCR, western blot, luciferase assays and electrophoretic mobility-shift assay, POU4F3 was proved to directly regulate the expression of STRC, GJB2 and CDC14A respectively. …”
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Localization and expression of C1QTNF6 in chicken follicles and its regulatory effect on follicular granulosa cells by Chong Li, Qi Li, Xing Wu, Zihao Zhang, Jing Li, Ruirui Jiang, Guoxi Li, Xiaojun Liu, Xiangtao Kang, Zhuanjian Li, Donghua Li, Yadong Tian

“…We demonstrated that the putative C1QTNF6 protein shares a highly conserved amino acid sequence with known bird homologs. Using quantitative real-time PCR (qRT-PCR) and fluorescence in situ hybridization (FISH), we observed that C1QTNF6 is widely expressed in adult chicken follicle tissues, predominantly in granulosa cells (GCs). …”
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Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-α- and Interleukin-1β-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Ox... by Jia Lv, Yongsheng Liu, Shuhan Jia, Yuna Zhang, Haoyang Tian, Jingyuan Li, Hui Song

“…The protein and mRNA expression levels of adherens junction molecules (VE-cadherin and β-catenin) and tight junction molecules (zona occludens-1, ZO-1) were studied using western blot analysis and reverse transcription-quantitative polymerase chain reaction (RT-PCR). The mRNA and protein expression levels of these cytokines were also analyzed in HGFs transiently transfected with HO-1 small interfering RNA (siRNA) in response to TNF-α and IL-1β stimulation. …”
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The Generation and Modulation of Distinct Gamma Oscillations with Local, Horizontal, and Feedback Connections in the Primary Visual Cortex: A Model Study on Large-Scale Networks by Chuanliang Han, Tian Wang, Yujie Wu, Yang Li, Yi Yang, Liang Li, Yizheng Wang, Dajun Xing

“…We created a computational model composed of multiple excitatory and inhibitory units with biologically plausible connectivity patterns for RC, FF, FB, and HC in V1; then, we quantitated GAMMA in network models at different strength levels of HC and other connection types. …”
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Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses by Lifen Liu, Yang Liu, Rui Li, Yue Teng, Shuyang Zhao, Jinhong Chen, Changjiang Li, Xinyu Hu, Lin Sun

“…Anxiety and depression in a mice stress model were assessed using the open‐field test (OFT), elevated plus maze test (EPMT), and forced swimming test (FST). Real‐time quantitative PCR (qRT‐PCR) was conducted to validate key genes in stress‐exposed models. …”
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Clinical Significance of Perioperative Minimal Residual Disease Detected by Circulating Tumor DNA in Patients With Lung Cancer With a Long Follow-up Data: An Exploratory Study by Shuta Ohara, MD, PhD, Kenichi Suda, MD, PhD, Sumedha Sudhaman, PhD, Akira Hamada, MD, PhD, Masato Chiba, MD, PhD, Masaki Shimoji, MD, PhD, Toshiki Takemoto, MD, PhD, Ekaterina Kalashnikova, PhD, Samantha K. Cheung, PhD, Michael Krainock, MD, PhD, Jordan Feeney, BS, Himanshu Sethi, MPH, Minetta C. Liu, MD, Junichi Soh, MD, PhD, Yasuhiro Tsutani, MD, PhD, Tetsuya Mitsudomi, MD, PhD

“…A clinically validated, personalized, tumor-informed 16-plex polymerase chain reaction–next-generation sequencing assay was used for the detection and quantification of ctDNA in retrospectively analyzed plasma samples. …”
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Probe – Integrated electrochemical sensing platform for detection of trace levels of Dapoxetine hydrochloride drug residue in water and drug formulations by H. Alwael, N.A. Asiri, B.G. Alhogbi, A.S. Alharthi, E.A. Bahaidarah, T.N. Abduljabbar, D.F. Baamer, M. Madkour, F.A. Zainy, M.S. El-Shahawi

“…The proposed probe displayed limits of detection (LOD) and quantification (LOQ) of 5.0 × 10−7 and 1.56 × 10−6 M, respectively, with a wide linear dynamic range (LDR) of 1.0 × 10−6–1.0 × 10−4 M of DPH. …”
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Production of β-lactoglobulin (BLG) gene knock- out blastocyst stage embryos of Indian water buffalo using CRISPR and SCNT technology by Aseem Tara, Priyanka Singh, Devika Gautam, Gaurav Tripathi, Shreya Malhotra, Sacchinandan De, Manoj K. Singh, Naresh L. Selokar

“…Breeding strategies, nutritional management, and quantitative genetics have improved milk yield, but these approaches could not lead to significant changes in milk composition. …”
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Superior biomechanical stability of pedicle screws compared to lateral mass screws: recommendations for bicortical positioning and enhancing bone contact in geriatric C1 vertebrae by Leon-Gordian Leonhardt, Leonie Rörup, Anna Lena Kammal, Michael Hahn, Marc Dreimann, Benjamin Ondruschka, Felix Nikolai von Brackel, Tim Rolvien, Lennart Viezens, Simon von Kroge

“…Additionally, the mechanical stability of LMS and PS fixation in mono- and bicortical positioning was tested by mechanical loading. High-resolution quantitative computed tomography was used to analyze the bone microstructure of cylinders corresponding to the trajectories of PS and LMS in mono- and bicortical locations in each C1. …”
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Evaluating Explainable AI Methods in Deep Learning Models for Early Detection of Cerebral Palsy by Kimji N. Pellano, Inga Strumke, Daniel Groos, Lars Adde, Espen F. Alexander Ihlen

“…Specifically, we use XAI evaluation metrics &#x2014; namely faithfulness and stability &#x2014; to quantitatively assess the reliability of Class Activation Mapping (CAM) and Gradient-weighted Class Activation Mapping (Grad-CAM) in this specific medical application. …”
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Assessment of prognosis and responsiveness to immunotherapy in colorectal cancer patients based on the level of immune cell infiltration by Kaili Liao, Minqi Zhu, Lei Guo, Zijun Gao, Jinting Cheng, Bing Sun, Yihui Qian, Bingying Lin, Jingyan Zhang, Tingyi Qian, Yixin Jiang, Yanmei Xu, Qionghui Zhong, Xiaozhong Wang

“…The prognostic potential of the models was quantitatively assessed using Cox regression analysis and the development of column line plots. …”
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Organizational readiness and implementation of colorectal cancer screening evidence-based interventions in federally qualified health centers: A cross-sectional study by Emanuelle M. Dias, Timothy J. Walker, Bijal A. Balasubramanian, Paula M. Cuccaro, Lauren Workman, Abraham Wandersman, Maria E. Fernandez

“…Assessing organizational readiness can improve EBI implementation outcomes, but no studies have quantitatively examined the relation between organizational readiness subcomponents and implementation outcomes. …”
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