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18781
Warm and humid environment induces gut microbiota dysbiosis and bacterial translocation leading to inflammatory state and promotes proliferation and biofilm formation of certain ba...
Published 2025-01-01“…On the one hand saliva and tongue coating samples were also taken from human subjects with “Dampness Syndrome” for microorganism culturing and to assess biofilm formation, on the other hand the co-culture products of a macrophage cell line RAW264.7 and Candida albicans and the effect of tumor necrosis factor-α (TNF-α) were evaluated for their impact on the proliferation and biofilm-forming abilities of different bacterial strains. Results Compared to a control group, the treatment group exhibited significant changes in gut microbiota, including increased biofilm formation, which was mitigated by Huoxiang Zhengqi Water. …”
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18782
FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression
Published 2025-02-01“…Flow cytometry was used to observe the proliferation and apoptosis of MC38 cells, and Transwell assay to detect migration ability of MC38 cells. Five C57BL/6 macrophage-depleted mice (established with injection of clodronate liposome suspension through tail vein) received intraperitoneal implantation to construct a metastasis model, and then the obtained tumor masses were then weighted. …”
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18783
Effect of Dietary Vitamin C Ascorbic Acid on the Growth Performance and Immune Response of Betok Anabas testudineus Bloch
Published 2008-07-01“…Thus, inclusion of vitamin C in diet improved ability of fish to adapt to an extreme environment condition. …”
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18784
Application of evidence-based scene simulation combined with problem-based learning in clinical teaching of critical care for nursing students (基于循证的情景模拟结合PBL教学法在重症护理实习带教中的应用)...
Published 2022-03-01“…Conclusion The evidence-based simulation combined with problem-based learning is effective to arouse students’ motivation and interest in learning English, deepen the understanding of theoretical knowledge, improve the independent problem-solving ability and enhance the clinical practice skills. …”
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18785
Expression profile of FGF23, alpha klotho, microRNA-126, and wnt signaling pathway gene polymorphism in patients with acute or chronic kidney diseases: relation to dialysis require...
Published 2025-01-01“…While miR-126 and plasma FGF23 expression levels among CKD patients demonstrated high efficacy, with AUC values of 0.924 and 0.845, respectively. αKlotho's AUC of 0.786 indicated a moderate level of discriminatory ability. AKI and CKD may be associated with disrupted expression levels of FGF23, αKlotho, and miR-126, which may serve as possible biomarkers for CKD patients requiring dialysis. …”
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18786
Calibration and Verification of the AquaCrop Model in Simulating the Yield, Dry Matter and Water Productivity of Grain Corn (Zea mays L.) under Different Irrigation Methods and Nit...
Published 2025-12-01“…According to the obtained results, it can be concluded that AquaCrop was chosen well and within the expectations for the studied area and the ability of AquaCrop in the field to provide a low irrigation model like the wick method is suitable and practical.…”
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18787
Association of glucose to lymphocyte ratio with the risk of death in patients with atherosclerotic cardiovascular disease
Published 2025-01-01“…Receiver operating characteristic curve (ROC) analysis was conducted to assess the predictive ability of GLR for survival. During a median follow-up of 6.25 years, 624 deaths from various causes were observed, with 254 deaths from CVD. …”
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18788
Evaluation of Yield, Yield Component and Usefulness Indices of Bean (Phaseolus vulgaris) and Maize (Zea mays) Intercropping under Inoculation with Rhizobium phaseoli
Published 2025-12-01“…This shift indicates that maize had a lower competitive ability compared to beans in inoculated conditions within the mixed cropping system. …”
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18789
Utility of 131I-HLX58-Der for the Precision Treatment: Evaluation of a Preclinical Radio-Antibody-Drug-Conjugate Approach in Mouse Models
Published 2025-01-01“…Leveraging the radiosensitizing ability of Deruxtecan (DXd) and the internal radiation therapy of 131I for tumors, we aimed to develop the first radio-antibody-drug conjugates (RADCs) for the treatment of gastric cancer.Methods: The CLDN18.2-specific antibody HLX58 was conjugated with the payload DXd through a cleavable maleimide glycynglycyn-phenylalanyn-glycyn (GGFG) peptide linker. …”
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18790
Aides à la navigation, pratique de la navigation et construction des paysages maritimes en Atlantique du Nord-Est : quelques éléments de réflexion
Published 2020-12-01“…Navigation without a chart or instruments depended on a pilot’s knowledge and ability to use the wind, the stars and the reading of the landscape to safely steer a ship to its destination. …”
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18791
Targeted Next-Generation Sequencing in Pneumonia: Applications in the Detection of Responsible Pathogens, Antimicrobial Resistance, and Virulence
Published 2025-01-01“…., Nanjing, 210018, People’s Republic of China; 6Department of Pulmonary and Critical Care Medicine, Zhoushan Branch of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Zhoushan, 316000, People’s Republic of China; 7Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Fang, Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email fj40517@rjh.com.cn Min Zhou, Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin 2nd Road, Shanghai, 200025, People’s Republic of China, Email doctor_zhou_99@163.comBackground: Targeted next-generation sequencing (tNGS) is a high-throughput and cost-effective diagnostic alternative for pneumonia, with the ability to simultaneously detect pathogens, antimicrobial resistance genes, and virulence genes. …”
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18792
Application of family somatosensory game intervention in rehabilitation of COPD patients after discharge from hospital (家庭体感游戏干预在COPD患者出院后康复中的应用研究)...
Published 2021-01-01“…Conclusion Family somatosensory game intervention can significantly improve the quality of life, activity ability and treatment compliance of patients, and improve their quality of life after discharge form hospital. …”
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18793
Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy
Published 2025-02-01“…IntroductionRheumatoid arthritis (RA) primarily affects the joints but can also affect multiple organs and profoundly impacts patients’ ability to carry out daily activities, mental health, and life expectancy. …”
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18794
The authority of the printed word in the Lithuanian village of the XIX century
Published 2024-08-01“…Prayer books and other religious publications did not require much promotion; they were willingly bought. The ability to read was rather limited for the major part of the population. …”
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18795
Convolutional neural networks for sea surface data assimilation in operational ocean models: test case in the Gulf of Mexico
Published 2025-01-01“…Our findings reveal significant correlations between the chosen training window size – a factor not commonly examined – and the CNNs' ability to assimilate observations effectively. We also establish a clear link between the CNNs' architecture and complexity and their overall performance.…”
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18796
Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassip...
Published 2025-02-01“…Methods: In vitro antidiabetic activity was tested with α-amylase enzyme inhibition method and antioxidant activity was evaluated. Furthermore, their ability to quench free radicals was investigated using the 2,2-diphenyl-1-picryhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) free radical scavenging method and the superoxide dismutase (SOD) enzyme scavenging method was investigated. …”
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18797
Comprehensive evaluation of physico-chemical, antioxidant, and antimicrobial properties in commercial soaps: A study on bar soaps and liquid hand wash
Published 2025-02-01“…Combining all the parameters, SN 3 has good results among bar soaps with mild moisturizing and cleansing properties (MC-8.30 ± 0.035 %, FH-22.33 ± 0.29 cm), is safe for the skin (pH-9.83 ± 0.02, TAC-0.99 ± 0.03), has good TFM values (72.89 %), has proficient bacteria growth-inhibiting properties (ZI-18.67 ± 0.29 mm/100 % conc.) and has the ability to remove free radicals (357.41 ± 2.07 μg/mL). …”
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18798
Effects of flame retardant tributyl phosphate on early development of zebrafish
Published 2024-12-01“…The exposure time was from 2 hpf to 120 hpf and the hatching rate, malformation rate, heart rate and body length of zebrafish embryos at 72 hpf, the frequency of tail curling at 24-29 hpf, the locomotor ability at 96 hpf and the survival rate at 120 hpf were evaluated, respectively. …”
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18799
Application of problem-based learning combined with responsibility-based teaching model in the clinical teaching of nursing students (PBL教学法结合责任制教学在实习护生带教中的应用研究)...
Published 2023-12-01“…Conclusion The combination of PBL teaching and responsibility-based teaching can improve the comprehensive nursing ability of the nursing students during the internship. …”
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18800
Selection of lactic acid bacteria as a probiotic and evaluated its performance on gnotobiotic catfish Clarias sp.
Published 2018-05-01“…The selected isolate was tested in vivo to observe their ability to improve growth performances of catfish. …”
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