PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

“…In 786-O cells with low PTEN expression, further induction of PTEN overexpression significantly inhibited PI3K/AKT signaling activity (p < 0.01), accompanied by decreased cell viability and migration ability. These results indicate that the expression pattern of PTEN in RCC is complex, but its overexpression can exert tumor-suppressive effects by inhibiting the PI3K/AKT signaling pathway. …”
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SHP2 promotes the epithelial-mesenchymal transition in triple negative breast cancer cells by regulating β-catenin by Shihan Qian, Jingjing Zhu, Qing Han, Huang Cheng, Huaibin Zhou

“…The migratory and invasive abilities of TNBC cells in vitro, as well as the metastatic potential of TNBC in mouse xenograft models, were reduced after SHP2 depletion. …”
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PEMBELAJARAN BERBASIS LABORATORIUM VIRTUAL MELALUI GOOGLE CLASSROOM PADA MATERI HUKUM OHM UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS by Marini Amalia Ocvianti, Dwi Sulisworo

“…Learning innovation during the Covid-19 pandemic using Google Classroom is expected to foster the ability of educators to think critically. Research on the use of Google Classroom in virtual laboratory-based learning on Ohm’s Law has been carried out for 3rd grade students at SMA Muhammadiyah 1 Yogyakarta. …”
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Interpretable machine learning and radiomics in hip MRI diagnostics: comparing ONFH and OA predictions to experts by Tariq Alkhatatbeh, Ahmad Alkhatatbeh, Qin Guo, Jiechen Chen, Jidong Song, Xingru Qin, Wang Wei

“…DCA (Decision Curve Analysis displayed that the radiomics-model had a greater clinical benefit in differentiating OA and ONFH.ConclusionWe have successfully constructed and evaluated an interpretable radiomics-based machine learning model that could distinguish between OA and ONFH. This method has the ability to aid both junior and senior medical professionals to precisely diagnose and take prompt treatment measures.…”
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Differences in EEG complexity of cognitive activities among subtypes of schizophrenia by Hang Qi, Jilin Zou, Zhenzhen Yao, Gaofeng Zhao, Jing Zhang, Chunlei Liu, Min Chen

“…The study sample comprised 30 healthy controls, 19 patients with deficit schizophrenia, and 19 patients with non-deficit schizophrenia, all aged between 18 and 45 years. Cognitive abilities were evaluated using a change detection task. …”
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Early urea-to-creatinine ratio to predict rapid muscle loss in critically ill patients with sepsis: a single-center retrospective observational study by Jie Jiang, Hui Chen, Shan-shan Meng, Chun Pan, Jian-Feng Xie, Feng-Mei Guo

“…Conclusion The results demonstrate that ΔUCR is independently associated with rapid muscle loss in patients with sepsis and the AUC of the ROC curve for the ability of ΔUCR to predict rapid muscle loss was 0.76. …”
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Studying formation of <I>Pseudomonas aeruginosa</I> biofilms grown under different cultivation conditions by T. E. Mironova, V. S. Сherepushkina, V. N. Afonyushkin, N. V. Davydova, V. Yu. Koptev, A. S. Dimova

“…The topic is of great importance due to high incidence of P. aeruginosa-caused infections and P. aeruginosa resistance associated with its ability to form biofilms. The paper analyzes factors that influence biofilm formation, i.e.: growth phase used for inoculation (log, stationary), volume of the growth medium (0.2 and 1.0 ml) and concentration of nutrients (liquid nutrient media diluted to concentrations of 50; 25; 12.5 and 6%) in the cultivation volume. …”
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Relationship of monocyte to high-density lipoprotein ratio (MHR) and other inflammatory biomarkers with sarcopenia: a population-based study by Zhiwei Xue, Jian Cao, Jianhui Mou, Rui Wang, Peng Liu

“…The research first attempts to investigate the association between MHR and low muscle mass and to compare the predictive abilities of MHR, SII, NLR, and NHHR for low muscle mass risk. …”
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“Listening to understand,” exploring postpartum women’s perceptions of their social networks and social support in relation to their health behaviors and weight: A qualitative expl... by Jacqueline Kent-Marvick, Kristin G Cloyes, Ana Clark, Monica Angulo, Kayla de la Haye, Michelle Precourt Debbink, Cristina Creal, Bob Wong, Sara E Simonsen

“…Because the postpartum period is marked by unique challenges to a person’s ability to prioritize healthy behaviors, a multi-level/domain approach to intervention beyond the individual-level factors of diet and activity is needed. …”
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Trends and contributors of complete continuum of maternal healthcare service utilization in Ethiopia: a multivariate decomposition analyses by Ayal Debie, Molla M. Wassie, Claire T. Roberts, Murthy N. Mittinty, Annabelle Wilson, Jacqueline H. Stephens

“…Empowering women through education can enhance their decision-making ability regarding their own health.…”
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Coexistence of multiple leaf nutrient resorption strategies in urban forests by Pin Li, Zejin Wang, Kun Ran

“…The resorption activity of evergreen needle-leaf trees and ectomycorrhizal trees was found to primarily rely on stoichiometric control rather than nutrient limitation, whereas stoichiometry and nutrient limitation control strategies were both employed by deciduous broadleaf trees and arbuscular mycorrhizal trees, supporting their ability to adapt to changing environmental nutrient availability. …”
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Demography and homing behavior in the poorly-known Philippine flat-headed frog Barbourula busuangensis (Anura: Bombinatoridae) by Marta Miñarro, Patricia Burrowes, Claudia Lansac, Gregorio Sánchez-Montes, Leticia E. Afuang, Ignacio De la Riva

“…CMR data confirmed site fidelity, and translocation experiments revealed that frogs have the ability to home when displaced 10–50 m upstream and downstream from their original capture site. …”
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Therapeutic Efficacy of <i>Lavandula dentata</i>’s Oil and Ethanol Extract in Regulation of the Neuroinflammation, Histopathological Alterations, Oxidative Stress, and Restoring Ba... by Aziza Antar, Eman S. Abdel-Rehiem, Areej A. Al-Khalaf, Abdelaziz S. A. Abuelsaad, Mohamed Abdel-Gabbar, Gaber M. G. Shehab, Ayman M. Abdel-Aziz

“…<b>Results</b>: The investigation revealed that the extract and essential oils obtained from <i>L. dentata</i> L. exhibited the ability to improve the modulation of electrolytes and ions across voltage- and ligand-gated ion channels. …”
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Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1 by Daiana Alvarez-Olmedo, Claire Kamaliddin, Theodore B. Verhey, May Ho, Rebekah De Vinney, George Chaconas

“…It is the most common tick-transmitted illness in the Northern Hemisphere. The ability of this pathogen to spread to a wide variety of locations results in a diverse set of clinical manifestations, yet little is known regarding vascular escape of the spirochete, an important pathway for dissemination. …”
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Treatment of Vascular Dementia by Using Fuyuan Capsule Combined with "Xingnao Kaiqiao" Acupuncture by LI Hongmei, WANG Xiaoqin, GUO Yang, SHI Hongxing, GUO Xiao, WANG Xue

“…The mini-mental state examination (MMSE) score, modified Hasegawa dementia scale (HDS-R) score, and modified Barthel index (MBI) score were compared between the two groups before and after treatment; the levels of serum superoxide dismutase (SOD) and malondialdehyde (MDA) of patients before and after treatment were measured and analyzed by colorimetry. …”
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Home-based strength and balance exercises for fall prevention among older individuals of advanced age: a randomized controlled single-blind study by Jian Zhou, Bo Liu, Jian-fang Xu, Fu-bai-hui Wang, Hui Ye, Jin-Ping Duan, Xin-wen Cui

“…We conducted a comprehensive geriatric assessment (self-care ability, muscle strength, mobility, cognition, and psychological status) at baseline and 12 months later and dynamic posture mapping for balance and gait.Results The test group had a decreased risk of falls compared to the control group (25.4%vs.44.3%, respectively; RR = 0.747; 95% CI: 0.551–0.975; p = 0.027). …”
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Predictive Policing and Enhancing Security Performance through Artificial Intelligence Applications by Bensalem Kheira

“…These models empower authorities to issue early warnings, develop contingency plans, and reduce potential casualties and economic losses. The ability to anticipate disasters reflects the broader utility of AI in enhancing societal resilience and preparedness. …”
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The influence of e-trust on a job performance model based on employees’ dynamic capabilities during a crisis caused by a Black Swan event by Katarzyna Tworek, Guangyan Luo, Marcin Paska, Anna Sałamacha

“…PURPOSE: In a crisis such as the COVID-19 pandemic, employees play a key role in the ability to survive and achieve both sufficient and outstanding performance in the organization. …”
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Lightweight Detection and Counting of Maize Tassels in UAV RGB Images by Hang Yang, Jiaji Wu, Yi Lu, Yuning Huang, Pinwei Yang, Yurong Qian

“…On the publicly available maize tassel detection and counting dataset (MTDC), DLMNet achieves an <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>A</mi><mi>P</mi><mn>50</mn></mrow></semantics></math></inline-formula> of 83.3%, which is 0.7% higher than YOLOv8, further demonstrating DLMNet’s excellent generalization ability. This study enhances the model’s adaptability to sunlight, enabling high performance under suboptimal conditions and offering insights for real-time intelligent agriculture monitoring with UAV technology.…”
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The Use of Electronic Consent (eConsent) Within the Ketamine for Long-Lasting Pain Relief After Surgery (KALPAS) Multicenter Trial by Doan LV, Burr J, Perez R, Martinez H, Cuevas R, Watt K, Wang J

“…When signing the eConsent, however, all potential participants are provided with a concise summary of the informed consent document, an approach not widely used by multicenter studies. eConsent has been noted to be beneficial to research staff when trying to gather informed consent from participants who live far away from the hospital, want to include their family and friends, and for researchers who can approach patients outside of their clinical appointments.Conclusion: The ability to consent patients remotely has allowed for a flexible workflow within sites and a more patient-centric process that focuses on including loved ones in the discussion and scheduling time to speak to a principal investigator. …”
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