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17961
Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis
Published 2025-02-01“…ROC curve analysis showed that the level of circ_PPARG in peripheral blood had a good ability to distinguish patients with FM from healthy controls. …”
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17962
HEMPSEED AND COTTONSEED OILS IN THE ACCESSIONS FROM THE VIR COLLECTION AS SOURCES OF FUNCTIONAL FOOD INGREDIENTS
Published 2019-10-01“…In the 1950s, industrial cotton was cultivated on a hundred thousand hectares in the country, and now there are signs of its restored growing. Both crops have the ability to restore the raw material base to produce textile fibers, seed and oil as well as the potential to improve functional food production, because they contain functional food ingredients in their oil capable of reducing human nutrition disorder risks, preventing or restoring nutrient deficiencies, preserving and improving health.Materials and methods. …”
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17963
Association of triglyceride-glucose related indices with mortality among individuals with MASLD combined with prediabetes or diabetes
Published 2025-02-01“…Furthermore, we employed restricted cubic spline (RCS) analysis to investigate potential dose-response relationships. The predictive ability of the TyG indices for mortality was assessed by analyzing the time-dependent area under the curve (AUC). …”
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17964
Association between the triglyceride-glucose index and liver fibrosis in adults with metabolism-related fatty liver disease in the United States: a cross-sectional study of NHANES...
Published 2025-01-01“…Furthermore, the area under the ROC curve (AUC) for the TyG index in predicting significant fibrosis in MAFLD patients was 0.73 (95% CI, 0.68–0.78), indicating moderate predictive ability. Conclusions In the general U.S. population, elevated TyG index levels were positively associated with an increased risk of LF in MAFLD patients.…”
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17965
Development and validation of a novel risk-predicted model for early sepsis-associated acute kidney injury in critically ill patients: a retrospective cohort study
Published 2025-01-01“…The model was externally validated using another ICU cohort and exhibited good predictive ability. Additional validation is needed to support the utility and implementation of this model.…”
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17966
Comparison of mechanical properties and shaping performance of ProGlider and ProTaper ultimate slider
Published 2025-01-01“…There were no significant differences in the number of pecking strokes to reach the apex and centering ability among groups shaped with PG and PUS at both rotation speeds. …”
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17967
Effects of Extraction Temperature on Physicochemical Properties and Antioxidant and Immunomodulatory Activities of Polysaccharides from Lycium ruthenicum Murr.
Published 2025-02-01“…The effect of extraction temperature on the antioxidant activity of LRPs was analyzed through the detection of DPPH, ABTS+, hydroxyl radicals, superoxide anion radical scavenging activity, and the reducing ability of potassium ferricyanide. The effect of extraction temperature on the immunomodulatory activity of LRPs was investigated by analyzing the effect of LRPs on RAW264.7 cell viability and cytokine secretion. …”
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17968
Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells
Published 2025-01-01“…Annexin V-FITC with a flow cytometer and DCFDA labeling were used to detect apoptosis induction and the ROS production associated with cell death. Quercetin’s ability to stop the cell cycle was evaluated via PI staining and the flow cytometer. …”
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17969
A data-driven machine learning algorithm to predict the effectiveness of inulin intervention against type II diabetes
Published 2025-01-01“…It allows for the comparison of prediction effect based on different features of an individual, assessment of prediction abilities for different individuals given their features, and establishes a connection between machine learning and nutritional intervention in T2DM treatment. …”
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17970
Small- to Large-Scale Electron Beam Powder Bed Fusion of Functionally Graded Steels
Published 2024-12-01“…The ability to control process parameters over time and build space in electron beam powder bed fusion (PBF-EB) opens up unprecedented opportunities to tailor the process and use materials of a different nature in the same build. …”
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17971
In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hi...
Published 2022-01-01“…Infectious agents such as SARS-CoV, MERS-CoV, and SARS-CoV-2 have emerged in recent years causing epidemics with high mortality rates. The quick development of novel therapeutic compounds is required in the fight against such pathogenic agents. …”
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17972
iTRAQ-based quantitative proteomic analysis of herbicide stress in Avena ludoviciana Durieu
Published 2025-01-01“…Overall, the results of this study demonstrated the complex response of the resistant biotype to herbicides and its ability to increase antioxidant capacity through up-regulated detoxification proteins, particularly cytochrome P450 (Q6YSB4), and defense proteins, particularly superoxide dismutase (Q0DRV6) and polyamine oxidase (Q7XR46). …”
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17973
Gut microbiota derived metabolite trimethylamine N-oxide influences prostate cancer progression via the p38/HMOX1 pathway
Published 2025-01-01“…A high-choline diet increases the risk of fatal prostate cancer, potentially mediated by the conversion of choline to the trimethylamine N-oxide (TMAO) by the gut microbiota.MethodsThe CCK8 assay was employed to investigate whether TMAO affects the proliferation ability of prostate cancer cells and to determine the appropriate drug concentration. …”
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17974
Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease
Published 2025-02-01“…Results Using machine learning algorithms, five biomarkers (TSPO, HIGD1A, NDUFAB1, NT5DC3, and MRPS30) were successfully identified, and a nomogram model with strong diagnostic ability and accuracy (AUC > 0.9) was constructed. …”
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17975
Bibliotherapy Services in Public Libraries: the Case of Lithuania
Published 2023-12-01“…Although librarians both independently and institutionally, usually through projects or occasional trainings deepen their knowledge in this field, yet its lack is still mentioned, and in particular, the lack of practical skills necessary for organizing more formal active bibliotherapy activities, which leads to a lack of confidence in their own abilities and induces them to limit themselves to the role of an event organizer with a guest lecturer. …”
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17976
Predictive modeling for durability characteristics of blended cement concrete utilizing machine learning algorithms
Published 2025-07-01“…Chloride penetration and carbonation resistance are critical durability attributes that assess concrete's ability to withstand challenging environmental conditions. …”
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17977
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17978
Research Status and Prospect of Quality Intelligent Control Technology in Facilities Environment of Characteristic Agricultural Products
Published 2024-11-01“…Through the application of the Internet of Things, big data and the new generation of artificial intelligence technology, it provides technical support for the construction and application of intelligent process quality control system for the whole growth period of characteristic agricultural products.…”
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17979
Psychological detachment from work predicts mental wellbeing of working-age adults: Findings from the 'Wellbeing of the Workforce' (WoW) prospective longitudinal cohort study.
Published 2025-01-01“…<h4>Conclusion</h4>The ability to psychologically detach from work during the first pandemic lockdown, and improvement in this recovery activity over time, predicted better mental wellbeing and quality of life in vocationally active adults after one year of a global crisis, irrespective of work status. …”
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17980
18F−Prostate−Specific Membrane Antigen PET/CT imaging for potentially resectable pancreatic cancer (PANSCAN−2): a phase I/II study
Published 2025-01-01“…Abstract Background Current diagnostic imaging modalities have limited ability to differentiate between malignant and benign pancreaticobiliary disease, and lack accuracy in detecting lymph node metastases. 18F-Prostate-Specific Membrane Antigen (PSMA) PET/CT is an imaging modality used for staging of prostate cancer, but has incidentally also identified PSMA-avid pancreatic lesions, histologically characterized as pancreatic ductal adenocarcinoma (PDAC). …”
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