Whole blood transcriptome profiles of trypanotolerant and trypanosusceptible cattle highlight a differential modulation of metabolism and immune response during infection by Trypan... by Peylhard, Moana, Berthier, David, Dayo, Guiguigbaza-Kossigan, Chantal, Isabelle, Sylla, Souleymane, Nidelet, Sabine, Dubois, Emeric, Martin, Guillaume, Sempéré, Guilhem, Flori, Laurence, Thévenon, Sophie

“…Exposed cattle include trypanosusceptible indicine breeds, severely affected by the disease, and West African taurine breeds called trypanotolerant owing to their ability to control parasite development, survive and grow in enzootic areas. …”
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Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility by Rosalyn W Sayaman, Masaru Miyano, Eric G Carlson, Parijat Senapati, Arrianna Zirbes, Sundus F Shalabi, Michael E Todhunter, Victoria E Seewaldt, Susan L Neuhausen, Martha R Stampfer, Dustin E Schones, Mark A LaBarge

“…We speculate that luminal epithelia are the ultimate site of integration of the variant responses to aging in their surrounding tissue, and that their emergent phenotype both endows cells with the ability to become cancer-cells-of-origin and represents a biosensor that presages cancer susceptibility.…”
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Overcoming barriers to engagement and adherence to a home-based physical activity intervention for patients with heart failure: a qualitative focus group study by Guy A MacGowan, Sarah Charman, Djordje G Jakovljevic, Nduka C Okwose, Nicola O'Brien, Sophie Cassidy, David Brodie, Kristian Bailey, Leah Avery

“…Home-based physical activity programmes have gained popularity to address these issues, although it is acknowledged that their ability to provide personalised support will impact on their effectiveness. …”
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Dietary inflammatory index and disability among older adults in Guangzhou: a cross-sectional analysis by Junbin Liao, Junbin Liao, Wenfeng Cai, Danrong Lin, Yuanyun Xiao, Yanxi Liu, Yahui Wang, Yuquan Zhong, Fan Xiao, Heng Fang, Yilu Yao, Yunfeng Lin, Jiewen Su, Siyu Sun, Bo Zhang, Yan Wang, Wei Zhu, Wei Zhu

“…Disability levels were assessed using the “Assessment Standard for Long-term Care Disability” from the Medical Insurance Bureau, including Activities of Daily Living (ADL), Cognitive Ability, and Sensory Perception and Communication Skills (SPCS). …”
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Experimental Investigation on Temperature-Resistant CO₂ Foam Flooding in a Heterogenous Reservoir by Mei Tian, Yi Wu, Yuhua Shi, Guohua Cao, Yu Sun, Maozhu Li, Wei Wang, Li Gao, Zhipeng Wang, Yiqiang Li

“…This work takes a high-temperature heterogenous sandstone oil reservoir as an example; the foaming performance of different surfactants was evaluated via foamability, thermal stability, crude oil tolerance ability, and dynamic blocking capacity. The profile control performance of the optimized foaming agent was investigated via dual-core gas flooding experiments. (1) The results show that QPJ-c featured good foaming stability, which made it present the largest foam comprehensive index, although its foaming volume was slightly lower than that of QPJ-b. …”
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The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…These nanovesicles, with their distinct physical properties and ability to penetrate target cells, may prove beneficial in conditions involving the depletion of M2 macrophages and M1 macrophage-induced diseases, potentially aiding in the reduction of inflammation and tissue injury.…”
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CWPO mechanism for toxic dye degradation in the presence of Cu@FbHAp catalyst: DFT study, performance analysis, response surface methodology, regeneration, and cost estimation by Youssef Miyah, Mohammed Benjelloun, Fatiha Mejbar, Salma Ssouni, Mohamed El-Habacha, Soulaiman Iaich, Noureddine El Messaoudi, Marouane Zerrouq, Mohammed Souilah, Anissa Lahrichi, Farid Zerrouq

“…DFT calculations show that BG is more reactive than MeO, with a lower energy gap, higher electrophilicity, and lower chemical hardness. However, its ability to accept electrons is slightly lower than MeO’s. …”
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Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction by Hongjian Zhou, Zhipeng Xu, Chun Jiang, Qiuyue Wu, Chuanyue Zhang, Zhenyu Liu, Xiaoxue Zhang, Weiwei Li, Yujia Pang, Jing Zhang, Wenju Pan, Min Chen, Xinyi Xia

“…Bioinformatics analysis revealed that IR induced splicing disorders in differentiation-related genes, thereby impairing the differentiation ability of primary spermatocytes. Mechanistically, This IR-induced disruption was linked to IR-induced inhibition of NF-κB/Rela and Bclaf1 activity. …”
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Natural Polymer Derivative-based pH responsive Nanoformulations Entrapped Diketo-tautomers of 5-fluorouracil for Enhanced Cancer Therapy by Anbazhagan Thirumalai, Koyeli Girigoswami, Karthick Harini, Venkatakrishnan Kiran, Pazhani Durgadevi, Agnishwar Girigoswami

“…However, its limited ability to penetrate cell membranes and its short half-life, caused by rapid metabolism, necessitate frequent administration of high doses to maintain effective therapeutic levels. …”
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A DNA-Methylated Sight on Autoimmune Inflammation Network across RA, pSS, and SLE by Xingqiang Wang, Dongyun Lei, Jie Ding, Shuang Liu, Li Tao, Fan Zhang, Jiangyun Peng, Jian Xu

“…Differentiating the cytokine methylation status will serve as valuable resource for researchers alike to gain better understanding of the epigenetic mechanisms of the three AIDs. …”
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Inhibitory effects of limonin on the proliferation of non-small cell lung cancer cells via targeting S-phase kinase-associated protein 2 by Zhu Jiaxian, Zhang Mengting, Li Shengqing, Liu Yongqiang

“…Then, flow cytometry was used to detect the cell cycle and apoptosis, while colony formation assay assessed the low-density proliferation ability of NSCLC cells. The matrigel 3D pelletization assay was performed to evaluate stem cell properties. …”
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Dynamic physiology and transcriptomics revealed the alleviation effect of melatonin on Reaumuria trigyna under continuous alkaline salt stress by Xuebo Li, Lei Wang, Heyi Wang, Rui Hao, Lunkai Gao, Hongbo Cui, Hai Wu, Xiaodong Wu, Tong Qiao, Weijie Bai, Liming Zhang

“…The key mechanism identified involves melatonin’s ability to increase antioxidant enzyme activity, reduce reactive oxygen species and hydrogen peroxide levels, and alter gene expression patterns.DiscussionTranscriptomic analysis revealed significant changes in gene expression, particularly in photosynthetic signal transduction, phytohormone signaling, MAPK signaling, and the peroxisome pathway, which are crucial for the plant’s response to alkaline salt stress. …”
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Evaluation of storage stability of refrigerated buffalo meat coated with hydrothermally treated potato starch incorporated with thyme (Thymus vulgaris) and ginger (Zingiber officin... by Sangam Dahal, Basanta Kumar Rai, Anish Dangal, Kishor Rai, Prekshya Timsina, Ramesh Koirala, Sanjay Chaudhary, Pankaj Dahal, Tanka Bhattarai, Angelo Maria Giuffrè

“…It can be concluded that the increase in TEO concentrations on starch coating increases the ability of buffalo meat to resist microbiological as well as chemical spoilage.…”
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MENINGKATKAN HASIL BELAJAR VIRUS MELALUI PEMBELAJARAN KONTEKSTUAL METODE CERAMAH DAN DISKUSI DENGAN TAKTIK BERKELILING MENGHAMPIRI SISWA PADA SISWA KELAS X SMA HANG TUAH 4 SURABAY... by Sunaryo Sunaryo, Diana Pratiwi

“…Hasil penelitian menunjukkan aktifitas belajar pada siklus I 61,18% dengan kriterian cukup, mengalami peningkatan dibanding sebelum tindakan, siklus II meningkat lagi  menjadi 81,76% dengan kriteria baik. Sedangakan hasil belajar sebelum tindakan nilai rata-rata kelas berkisar 52, persentase ketuntasan klasikal berkisar 50% (17 dari 34 siswa), setelah tindakan siklus I  mengalami peningkatan nilai rata-rata kelas menjadi 77, presentase ketuntasan klasikal 79,4% (27 dari 34 siswa). …”
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Implementasi konseling individual dengan teknik self management untuk meningkatkan kedisiplinan siswa by Irna Delima Nasution, Fauziah Nasution

“…Hasil penelitian ini menunjukkan bahwa: (1) Terdapat tiga jenis pelanggaran kedisiplinan yang sering dilakukan oleh siswa di sekolah MAN ini yaitu ketidakdisiplinan pada waktu, ketidakdisiplinan pada pembelajaran, dan ketidakdisiplinan terkait pakaian seragam dan kerapian . (2) Ada dua faktor yang dapat menyebabkan ketidakdisiplinan siswa di MAN ini yaitu faktor internal, maksudnya adalah faktor dari dalam diri siswa sehingga menyebabkan siswa ini kesulitan dalam mengelola atau memanajemen diri sehingga mendorong siswa untuk melanggar aturan disiplin dan faktor eksternal berupa pengaruh dari lingkungan siswa, baik lingkungan keluarga, karena pada lingkungan keluarga yang terkadang tidak stabil, serta adanya permasalahan dalam keluarga dapat menjadi faktor yang mempengaruhi siswa terhadap kedisiplinan serta dari lingkungan masyarakat, dan lingkungan teman sebaya yang mana perilaku dari teman sebaya ini dapat memengaruhi keputusan siswa dalam bertindak. (3) Guru BK di MAN ini menerapkan layanan konseling individual dengan menggunakan teknik self management untuk memperbaiki kedisiplinan siswa di sekolah, dan hasilnya adalah adanya perubahan terhadap kedisiplinan siswa yang dapat dilihat dari buku catatan poin pelanggaran siswa.…”
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Identification of a transcription factor AoMsn2 of the Hog1 signaling pathway contributes to fungal growth, development and pathogenicity in Arthrobotrys oligospora by Qianqian Liu, Kexin Jiang, Shipeng Duan, Na Zhao, Yanmei Shen, Lirong Zhu, Ke-Qin Zhang, Jinkui Yang

“…Introduction: Arthrobotrys oligospora has been utilized as a model strain to study the interaction between fungi and nematodes owing to its ability to capture nematodes by developing specialized traps. …”
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Hubungan antara Stres Akademik dengan Kecenderungan Gejala Somatisasi pada Mahasiswa Program Studi Kedokteran Tingkat Akhir Fakultas Kedokteran Universitas Andalas Angkatan 2015 by Viton Surya Irlaks, Arina Widya Murni, Rini Gusya Liza

“…Stres yang tidak dikontrol dengan baik dapat mempengaruhi terjadinya gejala somatisasi. …”
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One-Pot Synthesis and Enhanced Vis-NIR Photocatalytic Activity of NiTiO₃/TiO₂ Templated by Waste Tobacco Stem-Silks by Weidong Yuan, Xiaohong Chen, Yi Zhao, Ying Fang, Han Zhang, Daomei Chen, Jiaqiang Wang

“…The boosting photocatalytic activity has been shown to be attributed to efficient charge separation and transfer across a direct Z-scheme heterojunction between NiTiO₃ and TiO₂ and enhanced light-harvesting ability of special flaky structure reduplicated from tobacco stem-silks. …”
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Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering by Afsaneh Jahani, Mohammad Sadegh Nourbakhsh, Ali Moradi, Marzieh Mohammadi, Lobat Tayebi

“…Cartilage tissue engineering (CTE) integrates cells, scaffolds, and signaling molecules, with Insulin being utilized as a differentiation biomolecule due to cost-effectiveness, dose-dependent influence on chondrogenesis, suitable biological activity, and ability to activate relevant receptors. Yet, administering differentiation biomolecules through conventional scaffolds poses a persistent challenge. …”
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New Evidence for <i>Cotinus coggygria</i> Scop. Extracts Application in Gastrointestinal Ailments by Dejan Stojković, Nina Dragičević, Marija Ivanov, Nevena Gajović, Milena Jurišević, Ivan Jovanović, Marina Tomović, Jelena Živković

“…Conclusions: The traditional use of <i>C. coggygria</i> for gastrointestinal diseases may be substantiated by its ability to inhibit the growth of harmful microorganisms and its promising cytotoxic properties. …”
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