An Injectable Hydrogel Bioimplant Loaded with Engineered Exosomes and Triple Anti-Tuberculosis Drugs with Potential for Treating Bone and Joint Tuberculosis by Huang J, Li H, Mei Y, Yi P, Ren Y, Wang Y, Han L, Tang Q, Liu D, Chen W, An Y, Hu C

“…The liposomes coated in hydrogel can release three kinds of anti-tuberculosis drugs smoothly and slowly, achieving a long term anti-tuberculosis.Conclusion: The composite bio-scaffold shows good tissue repair and long-term anti-tuberculosis abilities, which expected to provide a viable treatment plan for bone-related BJTB.Keywords: hydrogel scaffolds, engineered exosomes, triple anti-tuberculosis drugs loaded, bone and joint tuberculosis, therapy…”
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Beneficial Effects of <i>In Vitro</i> Reconstructed Human Gut Microbiota by Ginseng Extract Fermentation on Intestinal Cell Lines by Margherita Finazzi, Federica Bovio, Matilde Forcella, Marina Lasagni, Paola Fusi, Patrizia Di Gennaro

“…Among the natural compounds that we can introduce by the diet, <i>Panax ginseng</i> extract is one of the most utilized since it contains a vast number of bioactive molecules such as phenolic acids, flavonoids, and polysaccharides that have been shown to possess antioxidant, anti-ageing, anti-cancer, and immunomodulatory activity. In this work, the ability of a <i>P. ginseng</i> extract in combination with a probiotic formulation was taken into consideration to evaluate its effects on the modulation of <i>in vitro</i> reconstructed human gut microbiota (HGM). …”
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Volatility dynamics of stock returns, liquidity and exchange rates in ASEAN Countries by David Umoru, Beauty Igbinovia, Emoabino Muhammed, Rashidat Inobemhe Ali

“…In Thailand and Indonesia alike, returns significantly and positively responded to variation in money supply, while the volatility in the market and currency rate exchange adversely impacted returns. …”
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Vasoreactivity and inhaled treprostinil response in interstitial lung disease pulmonary hypertension by Eileen M. Harder, Farbod N. Rahaghi, Jane A. Leopold, David M. Systrom, George R. Washko, Aaron B. Waxman

“…Introduction Despite shared features with pulmonary arterial hypertension, acute vasoreactivity in pulmonary hypertension with interstitial lung disease (PH-ILD) is not well characterised, including its potential ability to predict therapeutic outcomes. We sought to determine whether acute vasoreactivity in PH-ILD to oxygen (O2) and inhaled nitric oxide (iNO) predicts inhaled treprostinil (iTre) outcomes. …”
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Optimal Dispatch of Reactive Power Using Modified Stochastic Fractal Search Algorithm by Thang Trung Nguyen, Dieu Ngoc Vo, Hai Van Tran, Le Van Dai

“…Compared to SSFS, the three modifications can bring advantages to MSFS such as using smaller number of produced solutions per iteration, spending shorter execution time, finding better optimal solutions, and owning more stable search ability. Furthermore, the proposed method also sees its effectiveness and robustness over SSFS by testing on IEEE 30-bus system and IEEE 118-bus system with three different single objectives for each system. …”
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Laser Induced Spectroscopy (LIBS) Technology and Environmental Risk Index (RI) to Detect Microplastics in Drinking Water in Baghdad, Iraq by Estabraq Mohammed Ati, Shahla Hussien Hano, Rana Fadhil abbas, Reyam Naji Ajmi and Abdalkader Saeed Latif

“…The presence of the measured micropolymer species in water was immediately classified and detected using a laser production resolution spectrometer as well as signal and plasma scattering spectra, various MP polymers “polyethylene terephthalate, polystyrene, polypropylene, polyethylene, and polyvinyl chloride” are five polymers that were successfully detected in drinking water to validate the ability to identify health risk factors based on potential environmental risk index (RI) and potential environmental risk factors (Tin), the results are calculated to show that risk predicates have evolved over a decade depending on the risk factors. …”
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A novel lightweight model for tea disease classification based on feature reuse and channel focus attention mechanism by Junjie Liang, Renjie Liang, Dongxia Wang

“…On the other hand, the popular vision transformer(ViT) model has a higher recognition accuracy as it has better global feature expression ability than CNN model. Since ViT models has a higher model complexity than CNN models, leading running slow on edge computing devices. …”
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Application of deep learning and feature selection technique on external root resorption identification on CBCT images by Nor Hidayah Reduwan, Azwatee Abdul Aziz, Roziana Mohd Razi, Erma Rahayu Mohd Faizal Abdullah, Seyed Matin Mazloom Nezhad, Meghna Gohain, Norliza Ibrahim

“…The aim of the current study is two-fold: to assess the performance of four deep learning models (DLM) in external root resorption (ERR) identification and to assess the effect of combining feature selection technique (FST) with DLM on their ability in ERR identification. Methods External root resorption was simulated on 88 extracted premolar teeth using tungsten bur in different depths (0.5 mm, 1 mm, and 2 mm). …”
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Dried and Tested: Inoculation Method Impacts Low-Moisture Food Persistent Bacterial Populations by Manita Adhikari, Kavita Patil, Jennifer C. Acuff

“…Pathogen contamination and harborage in low-moisture food (LMF) processing environments have resulted in outbreaks and recalls, but researchers are limited in their abilities to investigate solutions. Methods used in most laboratory studies do not accurately reflect the route of contamination or harborage of pathogens in LMF environments, which complicates studying of sanitation methods. …”
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Carvacrol acetate activated Nrf2 modulates mitophagy for the treatment of neurocyte oxidative stress induced by chlorpyrifos by Hong-Ling Zhou, Bei-Bei Wang, Xu-Li Fan, Xiao-Min Zhang, Ying Song

“…Administration of CAA significantly enhanced the locomotor ability of the rats, alleviated neuronal pathological alterations, and increased the number of Nissl bodies, while increasing autophagic bodies. …”
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How far? Travel burdens for children admitted to hospitals in the Western Cape Province of South Africa by M Richards, D le Roux, D Pienaar

“… Background: The ability to access effective hospital care for children is a significant determinant of good health outcomes. …”
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Effects of Dietary Vitamin C on the Growth Performance, Biochemical Parameters, and Antioxidant Activity of Coho Salmon Oncorhynchus kisutch (Walbaum, 1792) Postsmolts by Cong-mei Xu, Hai-rui Yu, Ling-yao Li, Min Li, Xiang-yi Qiu, Xiao-qian Fan, Yan-lin Fan, Ling-ling Shan

“…Based on the influences on growth, serum biochemical parameters, and antioxidative ability, an assessment of dietary VC requirement for coho salmon postsmolts (183.19±1.91 g) was conducted with a ten-week feeding trial. …”
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Resilience-based interventions in the public sector workplace: a systematic review by Malin H. L. Hollaar, Bram Kemmere, Paul L. Kocken, Semiha Denktaş

“…Results Included studies applied a wide range of definitions; most definitions fitted within the trait-orientation, conceptualizing resilience as an individual characteristic or ability, or the process-orientation, conceptualizing resilience as a dynamic process. …”
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Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol by Ruth Abrams, Aled Jones, Johanna Westbrook, Jill Maben, Russell Mannion, Judy M Wright, Mark Pearson, Justin Avery Aunger

“…These behaviours between healthcare staff are problematic; they affect people’s ability to work, to feel psychologically safe at work and speak up and to deliver safe care to patients. …”
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MUNet: a novel framework for accurate brain tumor segmentation combining UNet and mamba networks by Lijuan Yang, Lijuan Yang, Qiumei Dong, Da Lin, Chunfang Tian, Xinliang Lü

“…Furthermore, when validated on the independent LGG dataset, MUNet demonstrated excellent generalization ability, proving its effectiveness in various medical imaging scenarios. …”
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shRNA-interfered of Nrf2 reveals a critical role for Keap1-Nrf2 signaling pathway during effects of zearalenone induced oxidative stress in IPEC-J2 cells by Qun Cheng, Shu Zhen Jiang, Li Bo Huang, Wei Ren Yang

“…Conclusion These results further prove that interfering with the expression of Nrf2 in IPEC-J2 cells affected the activation of the Keap1-Nrf2 signaling pathway and reduced the ability of cells to resist ZEA-induced oxidative stress. …”
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Financial and non–financial factors in companies’ adaptation process towards sustainability and sustainable business models by Magdalena Zioło, Elżbieta Szaruga, Anna Spoz

“…The article aims to examine the relationship between financial and non-financial factors in enterprises and to indicate for which groups of enterprises the relationship of ESG and financial performance is most visible in the context of building sustainable business models and the ability to adapt to sustainability. The article assumes that enterprises’ financial and non-financial results determine their adaptability to sustainability, and there is a relationship between financial results, non-financial performance, and companies’ sustainable business models. …”
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Patterns of self-harm presentations at a Tertiary Urban Hospital in Kenya: A retrospective 5-year study (2018-2022). by Willie Njoroge, Catherine Gitau, Everline Onchari, Linnet Ongeri, Linda Khakali, Murad Khan, Zul Merali, Lukoye Atwoli, Jasmit Shah

“…<h4>Introduction</h4>Self-harm represents a complex and multifaceted public health issue of global significance, exerting profound effects on individuals and communities alike. It involves intentional self-poisoning or self-injury with or without the motivation to die. …”
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Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs by Elias A. Said, Sumaya Al-Dughaishi, Wadha Al-Hatmi, Iman Al-Reesi, Mohammed S. Al-Balushi, Atika Al-Bimani, Juma Z. Al-Busaidi, Marwa Al-Riyami, Murtadha Al-Khabori, Salam Al-Kindi, Francesco A. Procopio, Shadia Al-Sinawi, Aliyaa Al-Ansari, Crystal Y. Koh, Khalid Al-Naamani, Ali A. Al-Jabri

“…NAS TLRs and iAPCs had differential abilities to induce the production of MK, which was induced in monocytes and pDCs by all NAS TLRs (p<0.05) and in MDDCs by TLRs 7/8 (p<0.05). …”
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A nociceptor-specific RNAi screen in Drosophila larvae identifies RNA-binding proteins that regulate thermal nociception by Amber Dyson, Gita Gajjar, Katherine C. Hoffman, Dakota Lewis, Sara Palega, Erik Rangel Silva, James Auwn, Andrew Bellemer

“…Nociceptor neurons exhibit plasticity in which their sensitivity to noxious stimuli and subsequent ability to drive behavior may be altered by environmental conditions, injury, infection, and inflammation. …”
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