MRI-based deep learning and radiomics for predicting the efficacy of PD-1 inhibitor combined with induction chemotherapy in advanced nasopharyngeal carcinoma: A prospective cohort... by Yiru Wang, Fuli Chen, Zhechen Ouyang, Siyi He, Xinling Qin, Xian Liang, Weimei Huang, Rensheng Wang, Kai Hu

“…Conclusion: The Tf_Radiomics+Resnet101 model, based on MRI and Resnet101 deep learning, shows a high ability to predict the clinically complete response (cCR) efficacy of PD-1 inhibitor combined with GP in advanced NPC. …”
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Studying the Humoral Response against SARS-CoV-2 in Cuban COVID-19 Recovered Patients by Ivette Orosa Vázquez, Marianniz Díaz, Yaima Zúñiga Rosales, Klayris Amada, Janoi Chang, Ernesto Relova Hernández, Yaima Tundidor, Hilda Roblejo Balbuena, Giselle Monzón, Bárbara Torres Rives, Enrique Noa Romero, Danay Carrillo Valdés, Irinia Valdivia Álvarez, Aurora Delahanty Fernández, Claudia Díaz, Joaquín Solozabal, Mileidys Gil, Belinda Sánchez, Gertrudis Rojas, Beatriz Marcheco, Tania Carmenate

“…Our results suggest that disease severity, and not demographic features such as age, sex, and skin color, is the main determinant of the magnitude and neutralizing ability of the anti-RBD antibody response. An additional paired longitudinal assessment in 14 symptomatic convalescents revealed a decline in the antiviral antibody response and the persistence of neutralizing antibodies for at least 4 months after the onset of symptoms. …”
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Emulsifying Properties of Dried Soy-Whey, Dried Tofu-Whey, and Their Isolated Proteins by Sobral Pablo A., Ossa J. Sebastian Henao, Palazolo Gonzalo G., Wagner Jorge R.

“…Even though the stability to gravitational separation and coalescence increased with increasing protein concentration, freeze-dried whey samples exhibited a higher ability to form and stabilize emulsions respect to that of thermally-dried ones, especially for those obtained from soy-whey. …”
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Discovery of 15-deoxynaphthomycins activating the antioxidant NRF2-ARE pathway from Streptomyces sp. N50 via genome mining, global regulator introduction, and molecular networking by Min-Seon Kim, Baskar Selvaraj, Hee-Tae Yeo, Jun-Su Park, Jae Wook Lee, Jin-Soo Park

“…Also, the presence of quinone moieties in these compounds, which are known to activate NRF2, they were tested for their ability to activate NRF2. Among the new compounds, three (1, 5, and 6) activated the antioxidant NRF2-ARE signaling pathway. …”
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PERANCANGAN KAWASAN PELABUHAN PENUMPANG DI BODDIA KABUPATEN TAKALAR by Sriany Ersina, Burhanuddin Burhanuddin, Mursyidul Haq

“… Abstrak— Kota Makassar berkembang lebih pesat, baik secara sosial ekonomi maupun prasarana fisik. …”
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Successful establishment of CRISPR-based genome-edited clonal cell populations from primary cells of buffalo, goats, and sheep by Priyanka Singh, Bosco Jose, Devika Gautam, Aseem Tara, Shreya Malhotra, Sacchinandan De, Manoj K. Singh, Naresh L. Selokar

“… Genome editing technology has great potential for precise DNA modification in mammalian cells. The ability to precisely generate the clonal population of CRISPR-edited geno-type is of great importance in gene function/ pathway analysis, drug discovery, and production of genome-edited animals. …”
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Parent-implemented early intervention design for improving speech and language skills among Mandarin-speaking infants and toddlers with cleft lip and/or palate by Sha Lai, Li Lu, Zhongliang Zhou, Chi Shen, Binting Yang, Binting Yang, Zhanping Ren, Zhanping Ren, Siwei Ma, Siwei Ma, Siwei Ma

“…A parent-implemented early intervention was developed, including the following specific steps: health education within the hospital, 9 days of an online reading program in WeChat groups, face-to-face standardized training workshops, and individualized video feedback therapy.ConclusionWe have devised a parent-implemented early intervention to enhance speech and language abilities in Mandarin-speaking infants and toddlers with CL/P, overcoming the shortage of speech therapy services in China.…”
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Trying to Kill a Killer; Impressive Killing of Patient Derived Glioblastoma Cultures Using NK-92 Natural Killer Cells Reveals Both Sensitive and Highly Resistant Glioblastoma Cells by Jane Yu, Hyeon Joo Kim, Jordyn Reinecke, James Hucklesby, Tennille Read, Akshata Anchan, Catherine E. Angel, Euan Scott Graham

“…The overall goal of this work was to assess the ability of Natural Killer cells to kill cultures of patient-derived glioblastoma cells. …”
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Anti-HBs Positivity Related to Past HBV Infection and Vaccination in Older Adults in Polish Population—Cohort-Based Study by Katarzyna Zięba, Kacper Jagiełło, Joanna Musialik, Łukasz Wierucki, Adam Hajduk, Małgorzata Mossakowska, Jerzy Chudek

“…On the other hand, being ‘white collar’ and self-reliant, having the ability to use the Internet, and past surgical procedures in the last 5-year period were factors associated with a higher vaccination rate. …”
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Outlining the Psychological Profile of Persistent Depression in Fibromyalgia Patients Through Personality Assessment Inventory (PAI) by Andrea Doreste, Jesus Pujol, Eva Penelo, Víctor Pérez, Laura Blanco-Hinojo, Gerard Martínez-Vilavella, Helena Pardina-Torner, Fabiola Ojeda, Jordi Monfort, Joan Deus

“…<b>Results:</b> The PAI showed strong discriminative ability in detecting PDD, characterized by high scores in cognitive and emotional depression and low scores in identity alteration, dominance, and grandeur. …”
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LiDAR point cloud denoising for individual tree extraction based on the Noise4Denoise by Xiangfei Lu, Zongyu Ye, Liyong Fu, Huaiyi Wang, Kaiyu Wang, Yaquan Dou, Dongbo Xie, Xiaodi Zhao

“…For instance, in the S10 dataset, DEN4 attained a 70.2% diminution in MSE and a 37.8% augmentation in SNR in comparison with PTD.The findings demonstrate the efficacy of DEN4 in multiple forest datasets, its ability to maintain geometric integrity, and its enhanced stability without the necessity for pre-labelled data. …”
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Penerapan Model Pembelajaran Inkuiri Terbimbing Untuk Meningkatkan Kemampuan Berpikir Kreatif Siswa di SMAN 2 Kota Bengkulu by Wage Klaudhi Sintya, Andik Purwanto, Indra Sakti

“…Hasil penelitian ini menunjukkan bahwa aktivitas belajar siswa pada siklus I dengan rata-rata skor sebesar 22,5 pada kategori cukup, siklus II sebesar 25 pada kategori cukup dan siklus III sebesar 27 pada kategori baik. Kemampuan berpikir kreatif siswa pada siklus I diperoleh ketuntasan belajar klasikal sebesar 50% (tuntas), meningkat pada siklus II diperoleh ketuntasan belajar sebesar 93,33% (tuntas), dan meningkat pada siklus III diperoleh ketuntasan belajar sebesar 100% (tuntas). …”
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Analisis Peningkatan Produktivitas Tanaman Pangan Melalui Penerapan Green Teknologi by Muhammad Irfan Arya, rosanna rosanna rosanna, Detia Tri Yunandar D

“…Hasil aktivitas menunjukkan bahwa: (1) standar green teknologi memberikan kontribusi signifikan terhadap produkstivitas. (2) Sikap petani merupakan faktor penting yang yang sangat mempengaruhi perkembangan produksi di Kabupaten Bone dengan penggunaan green teknologi. (3) Praktik terhadap penggunaan green teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Wajo. (4) Kebijakan  terhadap penggunaan green teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Pinrang. (5) Penggunaan teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Sidrap. (6) Tata kelola dalam penggunaan green teknologi merupakan faktor dominan dalam perkembangan produksi padi di Kabupaten Soppeng. (7) Penggunaan standar teknologi yang ramah lingkungan akan menghasilkan limbah padi saat panen dalam bentuk kompos, bibit, serta makanan ternak ruminansia, yaitu hewan pemamah biak, seperti lembu, biri-biri, dan domba. (8) Penggunaan standar teknologi yang ramah lingkungan akan menghasilkan limbah padi pasca panen dalam bentuk sekam kasar, dedak, dan menir.…”
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Persepsi Guru dan Siswa terhadap P5 Topik Pengelolaan Sampah di SMA Ibrahimy Wongsorejo by Hardiyanti Utami, Tuti Mutia, Sumarmi Sumarmi, Heni Masruroh

“…Perlu adanya perubahan mindset dan persepsi yang baik terhadap kurikulum merdeka khususnya Projek Penguatan Profil Pelajar Pancasila (P5). …”
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Electroacupuncture Involved in Motor Cortex and Hypoglossal Neural Control to Improve Voluntary Swallowing of Poststroke Dysphagia Mice by Shuai Cui, Shuqi Yao, Chunxiao Wu, Lulu Yao, Peidong Huang, Yongjun Chen, Chunzhi Tang, Nenggui Xu

“…Four main conclusions can be drawn from our study: (i) EA may enhance the local field potential in noninfarction area of M1, activate the swallowing-related neurons (pyramidal cells), and increase the motor conduction of noninfarction area in voluntary swallowing; (ii) EA may improve the blood flow in both M1 on the healthy side and deglutition muscles and relieve PSD symptoms; (iii) EA could increase the motor conduction velocity (MCV) in hypoglossal nerve, enhance the EMG of mylohyoid muscle, alleviate the paralysis of swallowing muscles, release the substance P, and restore the ability to drink water; and (iv) EA can boost the functional compensation of M1 in the noninfarction side, strengthen the excitatory of hypoglossal nerve, and be involved in the voluntary swallowing neural control to improve PSD. …”
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Effects of Therapeutic Hypothermia and Minimal Enteral Nutrition on Short-Term Outcomes in Neonates with Hypoxic–Ischemic Encephalopathy: A 10-Year Experience from Oman by Manoj Malviya, Sathiya Murthi, Dhanya Jayaraj, Vidya Ramdas, Fadia Nazir Malik, Valsala Nair, Nusrabegam Marikkar, Mukesh Talreja, Tariq Sial, Prakash Manikoth, Renjan Varghese, Khalsa Ali Al Ramadhani, Salima Al Aisry, Said Al Kindi, Ahmed Al Habsi, Ranjit Torgalkar, Munawwar Ahmed, Mohammed Al Yahmadi

“…MRI score was a strong predictor of mortality (AUC: 0.89; <i>p</i> < 0.001) and of ability to orally feed at discharge (AUC: 0.73; <i>p</i> < 0.001). …”
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Metagenomic analysis of gut microbiota diversity in poultry before and after antibiotic administration by O. V. Prasolova, N. I. Malik, I. A. Timofeeva, N. A. Kirsanova, E. V. Krylova, E. V. Malik, I. A. Rusanov, N. A. Chupakhina

“…The revealed increase in the proportion of Lactobacillaceae during antibiotic treatment suggests the ability of a healthy organism to restore the microbiota balance. …”
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Silent magnetic resonance angiography diagnostic value of intracranial unruptured aneurysms by Bin Lv, Tingyang Zhang, Ning Wang, Lu Liu, Mingyu Li, Meng Li, Mingguang Sun, Xiao Zang, Xinfeng Liu, Rongju Zhang, Xiangyu Cao, Zhihua Du, Jun Wang, Jinhao Lyu, Xueyang Wang, Qi Duan, Fangfang Guo, Xin Lou, Chenglin Tian

“…In conclusion, S-MRA and 3D-TOF MRA did not significantly differ in aneurysm detection ability. For the detection of aneurysm with dauthger sacs indicators, the sensitivity is also higher.…”
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Clinical utility of receptor status prediction in breast cancer and misdiagnosis identification using deep learning on hematoxylin and eosin-stained slides by Gil Shamai, Ran Schley, Alexandra Cretu, Tal Neoran, Edmond Sabo, Yoav Binenbaum, Shachar Cohen, Tal Goldman, António Polónia, Keren Drumea, Karin Stoliar, Ron Kimmel

“…Results Here we show that the system identifies 30.5% of patients as hormone receptor-positive, achieving a specificity of 0.9982 and a positive predictive value of 0.9992, demonstrating its ability to determine eligibility for hormone therapy without immunohistochemistry. …”
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Penerapan Model Inkuiri Terbimbing Untuk Meningkat Sikap Ilmiah Dan Hasil Belajar Siswa Pada Konsep Alat-Alat Optik Kelas XI SMAN 1 Mukomuko by Siti Fadilah, Andik Purwanto, Eko Risdianto

“…Hasil penelitian ini menunjukkan bahwa sikap ilmiah pada siklus I sebanyak 8 siswa pada kategori baik, pada siklus II 23 siswa, dan meningkat pada siklus III 28 siswa. …”
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