A proposal of visual assessment of serotonergic deficits in parkinsonian syndromes: An 123I-FP-CIT SPECT study by Tomoko Totsune, Toru Baba, Yoko Sugimura, Hideki Oizumi, Hiroyasu Tanaka, Toshiaki Takahashi, Masaru Yoshioka, Ken-ichi Nagamatsu, Atsushi Takeda

“…Objectives: The aims of this study were to propose a visual assessment grading system of brainstem 123I-FP-CIT uptake and investigate the ability of this method to differentiate PD from PS. …”
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Highly pathogenic bovine viral diarrhea virus BJ-11 unveils genetic evolution related to virulence in calves by Yuanyuan Zhang, Yuanyuan Zhang, Jing Cheng, Yu Guo, Yu Guo, Yibin Hu, Yibin Hu, Zhuo Zhao, Wenxiao Liu, Linyi Zhou, Peize Wu, Chunjie Cheng, Chunjie Cheng, Chun Yang, Chun Yang, Jing Yang, Jing Yang, Enqi Du, Yongqing Li, Yongqing Li

“…Analysis of the E2 glycosylation site disappeared (298SYT) in one of the four common glycosylation sites in the BVDV-1, which has been reported to affect the ability of the virus to infect and an additional glycosylation site (122NGS). …”
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Bubble connectivity in experimentally-sheared crystal-bearing silicic melts by Daffos, Camille, Martel, Caroline, Arbaret, Laurent, Champallier, Rémi

“…The explosivity of an eruption is mainly controlled by the ability of gases to escape the magma column. Indeed, magmas able to evacuate gases mostly erupt effusively whereas magmas that retain pressurised gases are likely to trigger explosive events. …”
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Cerebral tissue oxygen saturation and its potential relationship with neurodevelopmental delay in pediatric liver transplant recipients by Yichen Fan, Qianling Pan, Henghua Su, Zhongchan Pu, Linjie Zhu, Bo Qi, Diansan Su, Liqun Yang, Dan Huang, Weifeng Yu

“…Following adjustment for PELD scores, significant differences between the two groups were observed for the incidence of neurodevelopmental delay in communication at 1 and 3 months follow-up (P = 0.019 and P = 0.020, respectively), fine motor at six months follow-up (P = 0.014), and problem-solving abilities at one year follow-up (P = 0.047). Moverover, the length of ICU stay (P = 0.009) and postoperative hospitalization (P = 0.029) in LS group were also significant prolonged.ConclusionThis prospective observational study revealed that the patients with low average SctO2 values were more predisposed to experiencing postoperative neurodevelopment delays, suggesting a potential association between decreased average SctO2 and neurodevelopmental delay.…”
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Establishment and internal validation of a model to predict the efficacy of Adalimumab in Crohn’s disease by Fang Wang, He Zhou, Yujie Zhang, Yu Da, Tiantian Zhang, Yanting Shi, Tong Wu, Jie Liang

“…Abstract Background: Clinically, the ability to distinguish which Crohn’s disease patients can benefit from Adalimumab is limited. …”
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Analisis Masalah Dan Solusi Live Streaming Shopping: Tinjauan Literatur Sistematis by Nandhita Zefania Maharani, Betty Purwandari, Imairi Eitiveni, Erisva Hakiki Purwaningsih

“…Namun, untuk memahami lebih baik tantangan dan solusi yang terkait dengan live streaming shopping, diperlukan tinjauan literatur yang komprehensif berdasarkan penelitian terdahulu. …”
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S100A8/A9 Molecular Complexes Promote Cancer Migration and Invasion via the p38 MAPK Pathway in Nasopharyngeal Carcinoma by Ning Xu, Bei-Bei Zhang, Xia-Ning Huang, Xiang Yi, Xue-Min Yan, Yan Cai, Qin He, Zi-Jian Han, Yuan-Jiao Huang, Wei Liu, Ai-Jun Jiao

“…Intriguingly, exogenous S100A8/A9 protein stimulation could dramatically enhance NPC migration and invasion abilities. In addition, p38 MAPK pathway blockade could diminish the migration and invasion of NPC cells stimulated by S100A8/A9 proteins. …”
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Alleviating <i>Clostridium perfringens</i>-Induced Intestinal Lesions in Chickens Using the Xylanase <i>Cb</i>Xyn10C and Its Binary Cocktail with a Protease by Wenjing Zhang, Zhenzhen Hao, Daoxin Yang, Wangli Ji, Kairui Guo, Xianhua Sun, Shuai Wang, Shuyan Yang, Jianshuang Ma, Tong Wang, Huiying Luo, Bin Yao, Meiling Zhang, Yuan Wang, Huoqing Huang, Xiaoyun Su

“…In this study, a xylanase (<i>Cb</i>Xyn10C), which effectively promotes the growth of probiotics, and a protease, which degrades the biofilm of <i>C. perfringens,</i> were analyzed for their ability to alleviate <i>C. perfringens</i>-induced necrotic enteritis in broiler chickens. …”
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Intrahepatic levels of microbiome-derived hippurate associates with improved metabolic dysfunction-associated steatotic liver disease by Maxime Deslande, Francesc Puig-Castellvi, Inés Castro-Dionicio, Romina Pacheco-Tapia, Violeta Raverdy, Robert Caiazzo, Guillaume Lassailly, Audrey Leloire, Petros Andrikopoulos, Yasmina Kahoul, Nawel Zaïbi, Bénédicte Toussaint, Frédérik Oger, Nicolas Gambardella, Philippe Lefebvre, Mehdi Derhourhi, Souhila Amanzougarene, Bart Staels, François Pattou, Philippe Froguel, Amélie Bonnefond, Marc-Emmanuel Dumas

“…Conclusions: Altogether, our results further highlight hippurate as a mechanistic marker of metabolic health, by its ability to improve metabolic homeostasis as a postbiotic candidate.…”
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Evaluation of twin-arginine translocation substrate proteins as potential antigen candidates for serodiagnosis of brucellosis by Yao Wu, Yao Wu, Xin Yan, Mingjun Sun, Xiaohan Guo, Jiaqi Li, Xiangxiang Sun, Xiangxiang Sun, Mengda Liu, Mengda Liu, Haobo Zhang, Haobo Zhang, Wenlong Nan, Weixing Shao, Fangkun Wang, Xiaoxu Fan, Xiaoxu Fan, Shufang Sun

“…Meanwhile, the combined protein group showed the strongest ability to detect Brucella in sheep serum, achieving an accuracy of 88.10%. …”
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Ethanol extract of Polygonatum cyrtonema Hua mitigates non-alcoholic steatohepatitis in mice by Dongliang Chen, Yue Shen, Yue Shen, Fang Huang, Bo Huang, Shangfu Xu, Shangfu Xu, Lisheng Li, Lisheng Li, Jie Liu, Zheng Li, Xia Li

“…Ingenuity pathway analysis of RNA-seq data revealed key canonical pathways and upstream molecules regulated by PCE.ConclusionOur findings confirm the ability of PCE in alleviating NASH and underscores AMPK/SIRT1 pathway as a potential theraputic target for NASH treatment.…”
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Establishment and practice of the gynecology Traditional Chinese Medicine nursing clinic based on the concept of medical and nursing integration (基于医护一体化的妇科中医护理专科门诊建设与实践)... by LI Shasha (李莎莎), LIU Ying (刘颖), ZHU Lei (朱磊), LIU Jing (刘静), LU Ying (卢英)

“…On the basis of doctors’ physique identification, the external treatment methods of traditional Chinese medicine represented by ear point treatment and acupoint application are comprehensively applied to help patients recover their health as soon as possible, so as to promote the development of traditional Chinese medicine nursing, improve the ability of TCM nursing service and highlight the characteristics of TCM. …”
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Analysis of the spatio-temporal impact of the built environment on shared bicycle ridership density by Na Li, Tianqun Wang

“…Shopping POI density shows different effects on shared bike use in different times and spaces. While the distance from the city center and the nearest distance to the bus station have a suppressive effect on shared bicycle use, they show opposite degrees of influence in the spatial distribution. …”
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Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome by Xinlei Sun, Shuang Qu, Fenglian Zhou, Fujie Shi, Yunfei Wu, Lin Gu, Minghui Liu, Zhen Bian, Lei Shi, Zhihong Liu, Yuan Liu, Ke Zen

“…Remarkably, Stx-laden monocytes demonstrate their ability to transport Stx2 to human renal glomerular endothelial cells (HRGEC), subsequently inducing apoptosis in HRGEC. …”
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Influence of COVID-19 Lockdown on Self-Efficacy in Endodontics among Dental Students by Jelena Vidas Hrstić, Ema Paljević, Ivana Brekalo Pršo, Ivana Vidović Zdrilić, Luka Šimunović, Elvis Božac, Romana Peršić Bukmir

“…It means that individuals who receive verbal encouragement affirming their abilities to succeed in specific tasks are more likely to exert increased efforts and maintain persistence.…”
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Uji Diagnostik Pemeriksaan Sifilis Metode Chemiluminescence Microparticle Immunoassay (CMIA) terhadap Treponema Pallidum Haemaglutination Assay (TPHA) by Erina Dwi Kumalasari, Muhammad Rizki Kurniawan, Siti Nur Fauziah

“…Uji Treponemal yang digunakan di laboratorium selain TPHA yaitu menggunakan metode CMIA (Chemiluminescene Microparticle Imunoassay) yang berkontribusi dalam upaya mendiagnosis perkembangan penyakit sifilis yang semakin parah dan mencegah penularan sifilis baik melalui hubungan seksual maupun penularan dari ibu ke janin pada saat kehamilan secara otomatis dan cepat. …”
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Graph analysis based on SCN reveals novel neuroanatomical targets related to tinnitus distress by Yawen Lu, Yifeng Yang, Meijing Yan, Lianxi Sun, Caixia Fu, Jianwei Zhang, Jianwei Zhang, Yuehong Liu, Kefeng Li, Zhao Han, Guangwu Lin, Shihong Li

“…Besides, a significant negative correlation between Tinnitus Handicap Inventory (THI) score and GMV in the left angular gyrus (r = −0.283, p = 0.040) as well as left superior temporal pole (r = −0.282, p = 0.041) were identified.ConclusionTinnitus patients showed reduced small-world properties, altered hub nodes, and reduced ability to respond to targeted attacks in brain network. …”
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Phenology analysis for trait prediction using UAVs in a MAGIC rice population with different transplanting protocols by Shoji Taniguchi, Toshihiro Sakamoto, Haruki Nakamura, Yasunori Nonoue, Di Guan, Akari Fukuda, Hirofumi Fukuda, Kaede C. Wada, Takuro Ishii, Jun-Ichi Yonemaru, Daisuke Ogawa

“…The CIg parameters were also effective for predicting DTH and SLW, and could also be used to predict panicle weight (PW). The predictive ability worsened when different cultivation protocols were used, but this deterioration was mitigated by a calibration procedure using data from parental cultivars. …”
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Polymeric Multivalent Fc Binding Peptides‐Fabricated Clinical Compounding Bispecific Antibody Potentiates Dual Immunotherapy Targeting PD1 and CTLA‐4 by Zongyu Liu, Hongyu Chu, Weidong Zhao, Chenguang Yang, Tongjun Liu, Na Shen, Zhaohui Tang

“…Mechanistically, a 6.3‐fold increase in PD1/CTLA‐4 BsAb accumulation in tumors due to the tumor targeting ability of aPD1, and the PD1/CTLA‐4 BsAb significantly reduces the adverse colitis event in healthy mice, compared to aPD1 and aCTLA‐4. …”
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Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection [version 2; peer review: 2 approved] by Raasti Naseem, Sara Pretorius, Nicola Howe, Clare Lendrem, Cameron Williams, Enitan D Carrol, Philip Pallmann

“…The “ideal” test should be rapid, point-of-care, cheap to procure, have capacity for high usability, and ability to be performed and interpreted by all staff. …”
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