Uji Aktivitas dan Karakteristik Kombucha Sari Buah Markisa (Passiflora edulis Sims) Terhadap Bakteri Escherichia coli dan Bacillus subtilis Secara In Vitro by Qothrunnada Shafa Salsabila, Ulfayani Mayasari, Irda Nila Selvia

“…Minuman fermentasi adalah minuman yang karena proses fermentasi menghasilkan bakteri asam laktat (BAL) yang baik bagi pencernaan manusia. Kombucha adalah minuman fermentasi yang dihasilkan dari simbiosis antara bakteri dan yeast dikenal dengan nama SCOBY (Symbiotic Culture Bacteria & Yeast). …”
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Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells by K. S. Young, G. R. Hancock, E. C. Fink, A. Zigrossi, B. Flowers, D. A. Cooper, V. T. Nguyen, M. C. Martinez, K. S. Mon, M. Bosland, D. R. Zak, A. P. Runde, M. N. Sharifi, I. Kastrati, D. D. L. Minh, S. Kregel, Sean W. Fanning

“…It enables endocrine therapy resistance by superceding intrinsic structural-energetic gatekeepers of ER hormone-dependence, it enhances metastatic burden by enabling neomorphic ER-dependent transcriptional programs, and it resists SERM and SERD inhibiton by reducing their binding affinities and abilities to antagonize transcriptional coregulator binding. …”
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Enhancement of Cognitive Benefits and Anti-Anxiety Effects of <i>Phytolacca americana</i> Fruits in a Zebrafish (<i>Danio rerio</i>) Model of Scopolamine-Induced Memory Impairment by Lucia-Florina Popovici, Ion Brinza, Florentina Gatea, Georgiana Ileana Badea, Emanuel Vamanu, Simona Oancea, Lucian Hritcu

“…Furthermore, these extracts demonstrated the ability to mitigate cholinergic deficits by inhibiting AChE activity and supporting antioxidant defense mechanisms through increased activity of antioxidant enzymes and reduced lipid and protein peroxidation. …”
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Longitudinal Range of the Eastward‐Traveling Equatorial Plasma Bubble Inducing Ionospheric Scintillation by P. Abadi, Y. Otsuka, S. Saito, M. Yamamoto, S. Perwitasari, I. N. Muafiry, A. Y. Putra, A. Faturahman

“…In conclusion, our research provides valuable insight into the ability of eastward‐traveling EPB to induce GNSS scintillation within a longitudinal range of 25°, thereby enhancing EPB and scintillation monitoring and prediction in regional space weather services.…”
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Wetland elevation change following beneficial use of dredged material nourishment by Brian D. Harris, Aleksandra Ostojic, Lenore P. Tedesco, Keith VanDerSys, Susan Bailey, Justin L. Shawler, Navid H. Jafari, Monica Chasten

“…This investigation allowed for a comprehensive examination of geotechnical modeling methods for planning wetland nourishments, including predicting the ability to keep pace with sea level rise. Ultimately, the two BUDM nourishments offset the effects of SLR by approximately 18-28 years.…”
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Predictive biomarkers for cardiometabolic risk in postmenopausal women: insights into visfatin, adropin, and adiponectin by Anna Maria Cybulska, Daria Schneider-Matyka, Ireneusz Walaszek, Mariusz Panczyk, Dorota Ćwiek, Anna Lubkowska, Elżbieta Grochans, Kamila Rachubińska, Katarzyna Malewicz, Mariusz Chabowski, Mariusz Chabowski

“…Visfatin is known for its pro-inflammatory properties and its ability to modulate insulin resistance. Adropin is involved in energy homeostasis and metabolic health, while adiponectin has anti-inflammatory and insulin-sensitizing effects. …”
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Seedling Stage Corn Line Detection Method Based on Improved YOLOv8 by LI Hongbo, TIAN Xin, RUAN Zhiwen, LIU Shaowen, REN Weiqi, SU Zhongbin, GAO Rui, KONG Qingming

“…These results demonstrate the model's ability to maintain high detection accuracy despite challenging conditions in the field.…”
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Optimization of Black Garlic Protein Extraction Process and Exploration of Its Properties and Functions with Enzymatic Hydrolysis Products by Jian Liu, Yuanyuan Wang, Bo Wang, Wei Zhang, Xiaoyu Ren, Youchuang Zhang, Lijun Jiang, Chunming Dong, Guihong Zhao

“…Compared to BGP, the hydrolysates demonstrated significantly improved solubility, water-holding capacity, and foaming ability (<i>p</i> < 0.05), while their emulsifying activity, emulsion stability, DPPH radical scavenging capacity, and hypoglycemic activity decreased. …”
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Implemantasi Mask R-CNN pada Perhitungan Tinggi dan Lebar Karang untuk Memantau Pertumbuhan Transplantasi Karang by Naufal Alkhalis, Husaini Husaini, Haekal Azief Haridhi, Cut Nadilla Maretna, Nur Fadli, Yudi Haditiar, Muhammad Nanda, Maria Ulfah, Kris Handoko, Intan Malayana, Arsa Cindy Safitri

“…Hasil penelitian menunjukkan bahwa dari ketujuh backbone yang diuji X101-FPN dan R101-DC5 menghasilkan presisi dan recall yang lebih baik. Selisih Average Presision (AP) antara kedua model terbaik tersebut untuk segmentasi mask pada Intersection over Union (IoU) maksimum sebesar 2,2% sedangkan untuk deteksi box sebesar 5,8%. …”
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Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity by Aboli Bhingarkar, Yuyin Wang, Keito Hoshitsuki, Katherine Marie Eichinger, Katherine Marie Eichinger, Sanjay Rathod, Yin Zhu, He Lyu, Andrew T. McNutt, Larry W. Moreland, Lee McDermott, David R. Koes, Christian A. Fernandez

“…In vivo studies assessed the ability of the compound to protect against TNFi immunogenicity, while ex vivo studies evaluated its effect on CD4+ T cell proliferation and B cell antibody secretion.ResultsWe identified duvelisib (DV) as a novel NFATC2 and NFATC1 inhibitor that attenuates NFAT transcriptional activity without inhibiting calcineurin or NFAT nuclear localization. …”
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A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor by Rebecca L. Brouillette, Christine E. Mona, Michael Desgagné, Malihe Hassanzedeh, Émile Breault, Frédérique Lussier, Karine Belleville, Jean-Michel Longpré, Michel Grandbois, Pierre-Luc Boudreault, Élie Besserer-Offroy, Philippe Sarret

“…Here, using BRET2-based biosensors, we demonstrated the ability of ARIP to inhibit agonist-induced β-arrestin recruitment on a series of 7TMRs that includes both stable and transient β-arrestin binders, with efficiencies that depend on receptor type. …”
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Breeding for Heat Tolerant Aromatic Rice Varieties and Identification of Novel QTL Regions Associated with Heat Tolerance During Reproductive Phase by QTL-Seq by Surangkana Chimthai, Sulaiman Cheabu, Wanchana Aesomnuk, Siriphat Ruengphayak, Siwaret Arikit, Apichart Vanavichit, Chanate Malumpong

“…Therefore, our objective was to develop heat-tolerant aromatic rice varieties using the pedigree method, focusing on selecting for seed-setting ability under extremely high temperatures along with the use of single nucleotide polymorphism/insertion and deletion (SNP/InDel) markers to improve aromatic properties and grain quality. …”
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Phycospheric Bacteria Alleviate the Stress of Erythromycin on <i>Auxenochlorella pyrenoidosa</i> by Regulating Nitrogen Metabolism by Jiping Li, Ying Wang, Yuan Fang, Xingsheng Lyu, Zixin Zhu, Chenyang Wu, Zijie Xu, Wei Li, Naisen Liu, Chenggong Du, Yan Wang

“…We found that 0.1, 1.0, and 10 mg/L ERY inhibited the growth and chlorophyll of microalgae, but the microalgae gradually showed enhanced growth abilities over the course of 21 days. As the exposure time progressed, the nitrate reductase activities of the microalgae gradually increased, but remained significantly lower than that of the control group at 21 d. …”
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Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

“…In aHUS, FHAAs target the C-terminus, thereby impacting FH ability to recognize cell surfaces. In C3G, in contrast, FHAAs often target the N-terminus, generating an acquired functional FH deficiency. …”
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Pengembangan Panduan Konseling Behavioral dengan Teknik Self-Management Berbasis Website LMS Schoology Untuk Meningkatkan Minat Belajar Siswa by Ketut Asta Suputra, Kadek Suranata, Gede Nugraha Sudarsana

“…Panduan ini merupakan instrumen bagi guru BK dalam menyelenggarakan layanan bimbingan konseling di sekolah. …”
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Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

“…This alarming trend threatens the country’s ability to provide equitable healthcare. Objective This study investigated the patterns and determinants of migration among doctors and dentists who graduated from the University of Benin, Nigeria, 15 years ago. …”
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Effects of Cellulase and <i>Lactiplantibacillus plantarum</i> on Chemical Composition, Fermentation Characteristics, and Bacterial Community of <i>Pennisetum giganteum</i> z.x.lin... by Zhili Wu, Xiongfei Zhang, Rongnuo Li, Jingtao Hui, Lu Deng, Inho Kim, Jie Wei, Junhu Yao, Xinjian Lei

Subjects: “…bio-additives…”
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Association between weight-adjusted-waist index and the prevalence of gallstone disease in Minhang District, Shanghai: a cross-sectional study by Jian Wang, Zixuan Zheng, Hongyu Tan, Shan Wei, Yufeng Gu, Yingsheng Cheng, Chengyan Xu, Wei Wang

“…WWI demonstrates superior predictive ability for gallstones compared to other obesity markers in obese populations. …”
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Intracranial aneurysm instability prediction model based on 4D-Flow MRI and HR-MRI by Fei Peng, Jiaxiang Xia, Fandong Zhang, Shiyu Lu, Hao Wang, Jiashu Li, Xinmin Liu, Yao Zhong, Jiahuan Guo, Yonghong Duan, Binbin Sui, Chuyang Ye, Yi Ju, Shuai Kang, Yizhou Yu, Xin Feng, Xingquan Zhao, Rui Li, Aihua Liu

“…We introduce a specialized ensemble learning framework, termed the Hybrid Model, which synergistically combines two heterogeneous base learning algorithms: 4D-Flow logistic regression (4D-Flow-LR) and Multi-crop Attention Branch Network (MicroAB-Net). The ability of the hybrid model to predict aneurysm instability was compared with baseline models: PHASES (population, hypertension, age, size, earlier rupture, and site) LR, ELAPSS (earlier subarachnoid hemorrhage, location, age, population, size, and shape) LR, aneurysm wall enhancement (AWE) LR, and Radiomics using the area under the curve (AUC) with Delong's test. …”
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Predictive method for poultry carcass visceral dimensions using 3D point cloud and Genetic Algorithm-based wavelet neural network by Zhengwei Zhu, Yan Chen, Lu Cai, Jinzhou Yang, Ke Wen, Jingjing Bao, Zhigang Hu, Dandan Fu

“…Finally, in order to verify the generalizability of the method, generalizability experiments were conducted on different breeds of poultry, which proved that the method of this study had superior generalizability ability. In the comparative analysis of the six models, the MAPE and RMSE of the GA-WNN model for the prediction of the three visceral dimensions were the lowest except for the RMSE for the prediction of visceral length. …”
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