Hippocampal Anti-inflammatory Effect of Electroacupuncture at Baihui and Shenting on Cognitive Dysfunction Induced by Systemic Inflammation by CHEN Xiaomei, PANG Lina, WANG Zhifu

“…After one week of adaptive feeding, 15 min before LPS injection, the EA group was given 10 Hz electrical stimulation at Baihui and Shenting acupoints, the intensity was 0.5 mA. 15 min after electrical stimulation, the model group and EA group were intraperitoneally injected LPS (1 mg/kg), the control group was given equal volume of solvent injection. 15 min before LPS injection and 24 h after LPS injection, the EA group was given the same electric stimulation for 15 min, and then the “what-where-when” behavioral test was performed to record the memory ability on the time, place and order of objects. After the behavioral experiment, immunofluorescence and ELISA were used to detect the changes of hippocampal Iba-1, TNF-α and serum TNF-α.Results1) Compared with the control group, the learning and memory time related to "what-where-when" in the model group was decreased (<italic>P</italic>&lt;0.01), and serum TNF-α (3 h after LPS) and hippocampal TNF-α (24 h) were significantly increased (<italic>P</italic>&lt;0.01); immunofluorescence and ELISA detection showed that hippocampal Iba-1 was significantly increased (<italic>P</italic>&lt;0.01) in the model group. 2) Compared with the model group, "what" and "when" learning time in the EA group increased (<italic>P</italic>&lt;0.01); the serum and hippocampal TNF-α were obviously decreased (<italic>P</italic>&lt;0.01 and <italic>P</italic>&lt;0.05); hippocampal Iba-1 in the EA group was decreased (<italic>P</italic>&lt;0.05).ConclusionElectroacupuncture at Baihui and Shenting may improve the cognitive dysfunction caused by systemic inflammation via inhibiting the activation of hippocampal microglia and reducing the release of inflammatory factor TNF-α in the peripheral blood and hippocampal regions.…”
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Identification of new genes regulating nodule development in Medicago truncatula: an in-silico approach by Mahboobeh Azarakhsh, Sara Eslami, Maryam Moghadas, Zahra Ataei

“…Among plants, legumes have the ability to fix nitrogen through symbiotic interaction with a specific group of bacteria called rhizobia. …”
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Hepatoprotective potential of Chrysin in a rat model of isoniazid- and rifampicin-induced hepatic injury: suppression of matrix metalloproteinase and transforming growth factor β by Deepa Mandlik, Akhilesh Tokey, Rohit Lokhande, Yash Dagadu, Heena Choudhary, Satish Mandlik

“…Abstract Background The ability of Chrysin (CHY) to scavenge free radicals has been widely explored. …”
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Advances in the Study of AI-assisted Diagnosis and Rehabilitation of ASD by Bosen MA, Xiaorong ZENG, Ran GONG, Farui LI

“…As for robot intervention equipment, while some studies explore methods and effectiveness of using robots to teach autistic children, others discuss the training of the ASD group's ability to perceive movements or combine the use of robots with traditional intervention techniques. …”
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Lysosome-related proteins may have changes in the urinary exosomes of patients with acute gout attack by Jitu Wang, Na Liu, Mei Hu, Man Zhang

“…The ROC analysis showed that CTSZ, AP1B1 and LAMP2 had a strong ability to predict acute gout attack, with AUC of 0.826, 0.847 and 0.882, respectively. …”
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Primary Study on Effect of Extraction Methods on the Properties and Activities of Polysaccharides from <i>Geum japonicum var. Chinense F. Bolle</i> by Xuan Chen, Ying-Bo Liu, Yong Deng, Jian-Yong Zhang

“…Conversely, ACE demonstrated highest Fe²⁺ chelating ability but the lowest activity in DPPH and ABTS assays. …”
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HISS: Snakemake-based workflows for performing SMRT-RenSeq assembly, AgRenSeq and dRenSeq for the discovery of novel plant disease resistance genes by Thomas M. Adams, Moray Smith, Yuhan Wang, Lynn H. Brown, Micha M. Bayer, Ingo Hein

“…This makes reproducibility and version control a challenge and limits the ability to perform these analyses to those with bioinformatics expertise. …”
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Anaemia in the Hospitalized Elderly in Tanzania: Prevalence, Severity, and Micronutrient Deficiency Status by Clara Chamba, Ahlam Nasser, William F. Mawalla, Upendo Masamu, Neema Budodi Lubuva, Erius Tebuka, Pius Magesa

“…Anaemia exhorts negative consequences to functional ability of elderly patients, both physically and cognitively. …”
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INTEGRATION OF INTRADISCIPLINARY TOPICS AND GEOGRAPHY IN THE TEACHING PROCESS OF TECHNOLOGY by M. S Kazimov

“…Thanks to the integrated teaching of Technology and Geography, it is possible for the students to learn the subject comprehensively and much better because integration creates conditions for the development of logical thinking and the formation of ability of independent thinking of students. Moreover, integrative teaching of subjects contributes to the build close relationship between the subjects and themes which have a positive impact on the creation of a dialogue and mutual understanding between teachers and students. …”
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Accurate Needle Localization in the Image Frames of Ultrasound Videos by Mohammad I. Daoud, Samira Khraiwesh, Rami Alazrai, Mostafa Z. Ali, Adnan Zayadeen, Sahar Qaadan, Rafiq Ibrahim Alhaddad

“…A key advantage of the proposed method is the ability to achieve accurate localization of the needle without altering the clinical workflow of the intervention.…”
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Investigating the Expression of c-Myc and BIRC5 in TRAIL and PBOX-15 treated Metastatic Prostate Cancer Cells by Corinne Kai Leng Chew, Hannah O'Toole, Daniela M Zisterer, Seema M. Nathwani, Jade K. Pollock

“…PBOX-15 presented an ability to sensitise cells to the effects of TRAIL, thus provide insight in potential application of the combination for metastatic prostate cancer.…”
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Hop to It! The Relationship Between Hop Tests and The Anterior Cruciate Ligament – Return to Sport Index After Anterior Cruciate Ligament Reconstruction in NCAA Division 1 Collegia... by Michael Zarro, Madelyn Dickman, Timothy Hulett, Robert Rowland, Derrick Larkins, Jeffrey Taylor, Christa Nelson

“…# Background Outcomes after anterior cruciate ligament reconstruction (ACLR) may not be optimal, with poor physical and psychological function potentially affecting return to sport (RTS) ability. Understanding the relationship between commonly used hop tests and the Anterior Cruciate Ligament -- Return to Sport Index (ACL-RSI) may improve rehabilitation strategies and optimize patient outcomes…”
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Detection of Vertical Root Fractures Using Cone-Beam Computed Tomography in the Presence and Absence of Gutta-Percha by Ehsan Hekmatian, Mitra Karbasi kheir, Hossein Fathollahzade, Mahnaz Sheikhi

“…The intracanal filling materials such as gutta-percha reduce the diagnostic ability of vertical root fractures. Hence, it is recommended to remove those materials from root canals before imaging to improve the diagnostic potential of CBCT.…”
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Synthesizing hybrid copper phosphate (Cu3(PO4)2) nanoflowers using Cu+2 and shed snakeskin: antioxidant, antibacterial, anticancer, guaiacol, anionic, and cationic dye degradation... by Cagri Caglar Sinmez, Fatih Doğan Koca

“…Abstract Background Synthesis of organic@inorganic hNFs is achieved by the coordination of organic compounds containing amine, amide, and diol groups with bivalent metals. The use of bio-extracts containing these functional groups instead of expensive organic inputs such as DNA, enzymes, and protein creates advantages in terms of cost and applicability. …”
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Cultural validation of the Addenbrooke’s Cognitive Examination Version III Urdu for the British Urdu-speaking population: a qualitative assessment using cognitive interviewing by Nadine Mirza, Maria Panagioti, Waquas Waheed

“…Across 19 ACE-III Urdu items, 7 required changes based on participant feedback: item 5a: fluency; items 6, 18 and 19: memory; items 12 and 13: language; and item 17: visuospatial abilities.The need for some of these changes was realised after 21 participants, due to persistently reoccurring issues, and these were applied before the last four participants. …”
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Application of different edge detection methods for faults identification in Anza Basin, Kenya by Gege Li, Qing Chen, Bingqiang Yuan, Xianfeng Tan, Hao Chen, Xiaoyu Huang, Lang Pan

“…However, the traditional potential field boundary identification method has limited ability to detect the boundaries of buried deep geological bodies. …”
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Soybean biochar as highly efficient adsorbent for ofloxacin from aqueous and CO2 from gaseous phase: Mathematical modelling and regeneration studies by Vaishnavi Gomase, Tejaswini Rathi, Aparna Muley, D. Saravanan, Ravin Jugade

“…The novelty of this approach lies in its ability to effectively remove both aqueous and gaseous pollutants, making it a versatile solution for environmental remediation. …”
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Assessment of genetic diversity of some Siberian and Far Eastern species of the genus Spiraea (Rosaceae) by newly developed multiplex panels of nuclear SSR loci by T. A. Poliakova, A. V. Shatokhina, G. N. Bondarenko, D. V. Politov

“…Three multiplex sets of 3, 3 and 2 loci, respectively, were developed and tested for ability to estimate the parameters of genetic variability and  population  structure in closely related species Spiraea ussuriensis, S. f lexuosa, S. chamaedryfolia representing seven natural populations of the Russian Far East and Siberia. …”
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Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes by K. V. Ustyantsev, E. V. Berezikov

“…Regenerative flatworms are informative model organisms which hold the keys to understand the mechanism of stem cell regulation and specialization during regeneration and homeostasis. Their ability to regenerate is fueled by the division and differentiation of the adult somatic stem cell population called neoblasts. …”
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Green synthesis of iron nanoparticles to promote seed germination of Zea mays under salinity condition by Hiba Fouad Abdulfatah, May Fahmi Abdulrahman, Enas Fahd Naji

“…PPE contains biomaterials that have the ability to synthesize Fe NPs through the reduction the iron precursor salt (FeSO4•7H2O) and also act as capping and stabilizing agents. …”
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