Design, synthesis and evaluation of benzofuran-acetamide scaffold as potential anticonvulsant agent by Shakya Ashok K., Kamal Mehnaz, Balaramnavar Vishal M., Bardaweel Sanna K., Naik Rajashri R., Saxena Anil K., Siddiqui H. H.

“…The majority of compounds exhibited anticonvulsant activity at a dose of 30 mg kg-1 body mass during 0.5-4 h, indicating their ability to prevent seizure spread at low doses. Relative to phenytoin, [N-(2-(4-chlorobenzoyl)benzofuran-3-yl)-2-(cyclohexyl( methyl) amino)-acetamide] (5i) and [N-(2-(4-chlorobenzoyl)benzofuran-3-yl)-2-(4-methylpiperidin-1- yl)-acetamide] (5c) demonstrated comparable relative anticonvulsant potency of 0.74 and 0.72, respectively, whereas [(N-(2-(4-chlorobenzoyl)benzofuran-3-yl)-2-(4-(furan-2-carbonyl)-piperazin-1-yl)-acetamide] (5f) exhibited the lowest relative potency of 0.16. …”
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The effect of cervical spine flexion-extension motion on odontoid parameters by Longao Huang, Dun Liu, Hongyuan Xu, Junfei Feng, Tao Kang, Shengwang Wei, Hua Jiang

“…OI can serve as a supplementary parameter for evaluating cervical sagittal balance and compensatory ability. The formula CL = 0.36×OI − 0.67×OT − 0.69×T1S provides the best predictions for physiological CL in the neutral position.…”
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The Convergent Validity of the SWAY Balance Application to Assess Postural Stability in Military Cadets Recovering from Concussion by Max K Dummar, Michael S Crowell, Will Pitt, Ai Mei Yu, Paige McHenry, Timothy Benedict, Jamie Morris, Erin M Miller

“…The SWAY mBESS in patients with concussion failed to demonstrate convergent validity and did not demonstrate an ability to validate known groups. When assessing the time to final RTA, the one-week post-initial assessment SCAT-5 symptom severity and total scores may help determine the length of recovery in this population…”
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Evaluating Meaningful Changes in Patient‐Reported Outcome Measurement Information System–Fatigue Scores from Three Phase 3 Clinical Trials of Sarilumab for Patients With Rheumatoid... by Clifton O. Bingham, Emily Molina, Amy Praestgaard, Stefano Fiore, David Cella

“…This study demonstrates the ability to convert FACIT‐Fatigue score onto the PROMIS T score metric, the rapid reduction in fatigue with biologic therapies, and the use of novel eCDF curves to show individual patient‐level change.…”
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Clinical Application of Laser Walking Stick in Subacute Hemiplegia Walking Training by XIONG Mingyue, ZHAO Yawen, PAN Zhe, TANG Mei, ZHENG Cheng, LUO Yi, TAN Jie

“…Objective: To observe the clinical application of laser cane in walking training of hemiplegic patients, and to explore the effect of a new visual cue device on the recovery of walking ability of hemiplegic patients.MethodsA total of 36 patients with subacute hemiplegia who met the inclusion criteria were randomly divided into observation group and control group, with 18 cases in each group. …”
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PLATFORM CAPITALISM AS THE SOURCE OF DIGITAL RENTIER’S SUPERPROFIT by I. M. Stepnov, J. A. Kovalchuk

“…The authors proved that the limitations of the ability to business control should lead to the fact that the expected return rate from the digital platform’s investments of the rentier should be significantly higher than for the shareholder. …”
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The evolution of primate vocal communication: a social route by Alban Lemasson, Camille Coye, Nancy Rebout, Florence Levréro

“…There is no doubt that different factors determine the evolutionary trajectory of a species' communication abilities. Beyond habitat, social life is likely a selection pressure. …”
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Performance of digital early warning score (NEWS2) in a cardiac specialist setting: retrospective cohort study by Amitava Banerjee, Riyaz Patel, Baneen Alhmoud, Daniel Melley, Tim Bonnici

“…Standardisation and integrated National Early Warning Score 2 (NEWS2) in electronic health records (EHRs) are recommended yet have not been evaluated in specialist settings.Objective To investigate the performance of digital NEWS2 in predicting critical events: death, intensive care unit (ICU) admission, cardiac arrest and medical emergencies.Methods Retrospective cohort analysis.Study cohort Individuals admitted with CVD diagnoses in 2020; including patients with COVID-19 due to conducting the study during the COVID-19 pandemic.Measures We tested the ability of NEWS2 in predicting the three critical outcomes from admission and within 24 hours before the event. …”
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Predictive Value of the Triglyceride-Glucose Index for Metabolic-Associated Fatty Liver Disease in Individuals with Different Metabolic Obese Phenotypes by Lv D, Wang Z, Liu H, Meng C

“…The critical values were 8.575, 9.075, 8.795, and 9.165, respectively.Conclusion: The TyG index is a reliable predictor of MAFLD risk, exhibiting a higher predictive ability for the risk of developing MAFLD in individuals with normal BMI compared to those with abnormal BMI. …”
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Overview of styles, content, learning effects and attitudes of students towards digitally enhanced physiotherapy education – a scoping review by Larissa Pagels, Oskar Schindler, Kerstin Luedtke

“…The integration of innovative digital strategies holds promise for the future of physiotherapy training, contingent on comprehensive support and training for educators and students alike.…”
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Origin and Development of Service Cynology in Modern Ukraine by V. S. Seliukov

“…The history of the origin and formation of service cynology in Ukraine has quite interesting aspects. First of all, at the time when the territory of modern Ukraine was part of the Russian Empire, and eventually the Soviet Union, the police service cynology was originated in Ukraine. …”
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Uncertainty-aware diabetic retinopathy detection using deep learning enhanced by Bayesian approaches by Mohsin Akram, Muhammad Adnan, Syed Farooq Ali, Jameel Ahmad, Amr Yousef, Tagrid Abdullah N. Alshalali, Zaffar Ahmed Shaikh

“…Traditional deep learning models rely on single-point predictions, limiting their ability to provide uncertainty measures essential for robust clinical decision-making. …”
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Effect of Composition and Processing Conditions on Selected Properties of Potato-Based Pellets and Microwave-Expanded Snacks Supplemented with Fresh Beetroot Pulp by Katarzyna Lisiecka, Agnieszka Wójtowicz, Agnieszka Sujak

“…The addition of fresh beetroot pulp diminished the expansion ability and increased the content of β-sheet proteins. …”
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Development of Chatbot-Based Oral Health Care for Young Children and Evaluation of its Effectiveness, Usability, and Acceptability: Mixed Methods Study by Kittiwara Pupong, Jaranya Hunsrisakhun, Samerchit Pithpornchaiyakul, Supawadee Naorungroj

“… Abstract BackgroundChatbots are increasingly accepted in public health for their ability to replicate human-like communication and provide scalable, 24/7 services. …”
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Economic Evaluation of a Novel Treatment of Attention-Deficit/Hyperactivity Disorder in US Motor Vehicle Drivers by Jacie T. Cooper, John E. Schneider, Jim Potenziano, David S. Fam

“…**Objective:** The aim was to evaluate the economic benefits attributable to improved driving abilities and avoided crashes in DXR patients compared with patients treated with the SOC or those who are untreated. …”
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Use of virtual care near the end of life before and during the COVID-19 pandemic: A population-based cohort study. by Kieran L Quinn, Thérèse A Stukel, Allan Detsky, Hannah Chung, Mohammed Rashidul Anwar, Sacha Bhatia, James Downar, Vivian Hung, Sarina Isenberg, Allison Kurahashi, Douglas S Lee, Nathan Stall, Peter Tanuseputro, Chaim M Bell

“…Virtual end-of-life care delivery may strengthen person-centredness for individuals with limited ability to attend in-person appointments and by providers who may not have previously engaged in such care.…”
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Use and impact of point-of-care ultrasonography in general practice: a prospective observational study by John Brodersen, Ole Graumann, Camilla Aakjær Andersen, Martin Bach B Jensen, Annette Sofie Davidsen

“…Objectives To describe how general practitioners (GPs) use point-of-care ultrasonography (POCUS) and how it influences the diagnostic process and treatment of patients.Design Prospective observational study using an online questionnaire before and after POCUS.Setting Office-based general practice.Participants Twenty GPs consecutively recruited all patients examined with POCUS in 1 month.Primary and secondary outcome measures We estimated the use of POCUS through the indication for use, the frequency of use, the time consumption, the extent of modification of the examination and the findings.The influence on the diagnostic process was estimated through change in the tentative diagnoses, change in confidence, the ability to produce ultrasound images and the relationship between confidence and organs scanned or tentative diagnoses.The influence of POCUS on patient treatment was estimated through change in plan for the patient, change in patient’s treatment and the relationship between such changes and certain findings.Results The GPs included 574 patients in the study. …”
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DIFFERENT HUMAN IMAGES AND ANTHROPOLOGICAL COLISSIONS OF POST-MODERNISM EPOСH: BIOPHILOSOPHICAL INTERPRETATION by S. К. Коstyuchkov

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Research on new energy power plant network traffic anomaly detection method based on EMD by Danni Liu, Shengda Wang, YutongLi, Ji Du, Jia Li

“…The efficiency of PV power plants and their ability to meet application requirements are both impacted by the communication infrastructures that are responsible for real-time monitoring. …”
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Should you hold onto the treadmill handrails or not? Cortical evidence at different walking speeds by Monica Biggio, Costanza Iester, Davide Cattaneo, Simone Cutini, Ambra Bisio, Ludovico Pedullà, Alessandro Torchio, Marco Bove, Laura Bonzano

“…Abstract Background Treadmill-based gait training is part of rehabilitation programs focused on walking abilities. The use of handrails embedded in treadmill systems is debated, and current literature only explores the issue from a behavioral perspective. …”
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