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13421
Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms
Published 2025-02-01“…The QOL-E domains/summary scores, except for QOL-SEX, had an adequate ability to detect change from baseline to Week 24. …”
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13422
Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up
Published 2025-01-01“…Furthermore, improvements in motor function of upper/lower extremities, sensory function of upper extremities, reading ability, and recreation domain scores were also significantly superior in the Yishenyangsui granule group compared to the placebo group (P < 0.05). …”
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13423
Impact of microwave processing on phytochemicals, antioxidant status, anti-nutritional factors and metabolite profile of maize flour
Published 2025-06-01“…DPPH scavenging (559.64–981.07 µg AAE/g) and ferric-reducing ability (790.18–1175.89 µg AAE/g) increased, whereas ascorbic acid content decreased (742.5–1423.75 µg/g). …”
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13424
Genome-Wide Identification and Expression Analysis of bHLH-MYC Family Genes from Mustard That May Be Important in Trichome Formation
Published 2025-01-01“…The trichomes of mustard leaves have significance due to their ability to combat unfavorable external conditions and enhance disease resistance. …”
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13425
Development and Validation of a Nomogram for Predicting Long-Term Net Adverse Clinical Events in High Bleeding Risk Patients Undergoing Percutaneous Coronary Intervention
Published 2025-01-01“…The nomogram exhibited strong predictive ability (the area under the curve (AUC) to predict 1-year NACE-free survival was 0.728), displaying favorable levels of accuracy, discrimination, and clinical usefulness in the internal validation cohort. …”
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13426
CT45A1‐mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell‐in‐cell structure, potentiating the progression of microsatellite...
Published 2025-02-01“…CT45A1‐expressing microsatellite stable (MSS) CRC cells showed enhanced migratory ability. However, CT45A1‐expressing MSI‐H CRC cells, but not MSS CRC cells, showed higher resistance to natural killer (NK) cell cytotoxicity and served as outer cells in homotypic CIC structures, preventing exogenous or therapeutic antibody access to inner CRC cells. …”
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13427
A generative whole-brain segmentation model for positron emission tomography images
Published 2025-02-01“…Additionally, clinical tolerance rates, which are determined by the tumor background ratio, have confirmed the ability of the method to distinguish highly metabolic regions accurately from normal regions, reinforcing its clinical applicability. …”
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13428
Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus
Published 2025-01-01“…All the constructed plasmids were then transformed into the sifA gene-deficient Salmonella vector χYL56 for oral immunization.The results showed that sifA-deficient Salmonella could efficiently increase antigen-specific mucosal sIgA antibody titers, especially in alveolar lavage samples, whereas the presence of the phage-54 nanobody could dramatically increase intracellular IFN-γ mRNA levels, indicating its ability to enhance the Th1-type immune response. Finally, the presence of the CpG adjuvant clearly increased T-cell proliferation and promoted DC activation, with elevated splenic TLR21 levels observed. …”
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13429
Empirical estimation of saturated soil-paste electrical conductivity in the EU using pedotransfer functions and Quantile Regression Forests: A mapping approach based on LUCAS topso...
Published 2025-02-01“…Soil Electrical conductivity (EC) is a measure of the ability of soil to conduct an electric current, which is primarily influenced by the concentration of soluble salts in the soil solution that takes place principally through water-filled pores. …”
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13430
Establishing a baseline for surgical care in Mongolia: a situational analysis using the six indicators from the Lancet Commission on Global Surgery
Published 2022-07-01“…This situational analysis shows one lower middle-income country’s ability to collect the indicators aided by a well-developed health information system.Design An 11-year retrospective analysis of the Mongolian surgical system using data from the Health Development Center, National Statistics Office and Household Socio-Economic Survey. …”
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13431
Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus
Published 2025-01-01“…ContextAs a novel SGLT1 inhibitor, SY-009 has been preliminarily confirmed in a phase Ib clinical study for its ability to reduce postprandial blood glucose in patients with type 2 diabetes mellitus (T2DM). …”
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13432
Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine
Published 2025-03-01“…Phytosomes, liposomes, nanocapsules, and nanoemulsions have ensured that bioactive ingredients' stability has been secured, bioavailability and targeted administration have been improved, and negative side effects have been cut considerably. The ability of nanoherbal formulations to deliver drugs to tumor cells in an improved permeability and retention manner, such as, cancer therapy while minimizing tissue damage, has been largely practiced in many laboratories. …”
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13433
Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model
Published 2024-04-01“…Ibrutinib, FDA-approved lymphoma agent, inhibits Bruton tyrosine kinase (BTK) and has previously been shown to independently impair aortic endothelial adhesion and increase rodent glioma model survival in combination with cytotoxic therapy. …”
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13434
Bilevel Optimization of Regular Bus-Subway-Shared Bicycle Cooperative Operation considering Dual Uncertainties
Published 2024-01-01“…By establishing a coordinated dual-level optimization model for regular bus, subway, and bike-sharing networks under dual uncertainty conditions, we employed convex combination techniques to unify the dual uncertain variables into a single objective, which was then incorporated into a chance-constrained bilevel programming model. …”
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13435
Microenvironment Influences on Human Umbilical Cord Mesenchymal Stem Cell-Based Bone Regeneration
Published 2021-01-01“…This study is aimed at investigating the effects of the in vitro culture microenvironment (hUC-MSCs, nano-hydroxyapatite/collagen/poly (L-lactide) (nHAC/PLA), osteogenic media (OMD), and recombinant human bone morphogenetic protein-7 (rhBMP-7)) and the in vivo transplanted microenvironment (ectopic and orthotopic) on bone regeneration ability of hUC-MSCs. The isolated hUC-MSCs showed self-renewal potential and MSCs’ characteristics. …”
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13436
The learning process of physical education lessons in education through virtual education
Published 2024-09-01“…The results obtained from the analysis showed that the educational limitation of movements and practical lessons, the lack of supervision and concentration in virtual education, the weak communication interaction between the teacher and students, the coverage of virtual classes, economic issues, the weakness of software and hardware technology and infrastructure, use of information technology in virtual education, insufficient knowledge of the space and capabilities of virtual education, lack of supervision and limitations on physical ability, and implementation of courses and capabilities of virtual education were categorized. …”
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13437
Investigating factors affecting the financial recovery of businesses admitted to the stock exchange
Published 2024-11-01“…On the other hand, bankrupt companies lose the ability to pay taxes to the government and are forced to fire their employees; which brings many social and political problems. …”
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13438
Designing a Model for Brand Engagement Value Creation through the Integration of Gamification Technology and Explainable Artificial Intelligence (XAI)
Published 2024-12-01“…On the other hand, bankrupt companies lose the ability to pay taxes to the government and are forced to fire their employees; which brings many social and political problems. …”
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13439
Development of a nomogram for predicting pancreatic portal hypertension in patients with acute pancreatitis: a retrospective study
Published 2024-06-01“…Using the largest cohort of patients with AP to date, we developed a highly accurate nomogram with strong discriminative ability for predicting PPH. Future studies with larger sample sizes are necessary to confirm our findings and conduct external validation.…”
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13440
Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User
Published 2025-01-01“…Meanwhile, to meet high spectrum utilization, Non-Orthogonal Multiple Access (NOMA) has emerged as a potential technology in the last decade, for its ability to serve multi-user communication simultaneously by exploiting power-domain rather than time or frequency domains. …”
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