PENGEMBANGAN KIT PRAKTIKUM ELEKTRONIKA DASAR II BERBASIS SIMULATOR PROTEUS UNTUK MENINGKATKAN KEMAMPUAN MAHASISWA DALAM PEMECAHAN MASALAH by Suwardi Suwardi, Erik Ayatullah, Haidul Haidul

“…Kata kunci: kit praktikum elektronika dasar II, simulator proteus, praktikum berbasis masalah     ABSTRACT   This study aims to develop a Basic Electronics II practicum kit based on the Proteus simulator to improve students' problem solving abilities. The results of observations in the pre-study showed that students had difficulty assembling electronic components, lack of practicum time, and difficulties in obtaining data. …”
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Frequency of remission achievement in the pre-treat-to-target decade in juvenile idiopathic arthritis by Ana Isabel Rebollo-Giménez, Angela Pistorio, Silvia Maria Orsi, Francesca Ridella, Elena Aldera, Luca Carlini, Valentina Natoli, Marco Burrone, Silvia Rosina, Roberta Naddei, Alessandro Consolaro, Esperanza Naredo, Angelo Ravelli

“…Future studies will determine whether the application of the T2T strategy increases the ability to achieve sustained disease quiescence in patients who respond suboptimally to the conventional therapeutic regimens.…”
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Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dsc... by Jacob M. Sadler, Alfred Simkin, Valery P. K. Tchuenkam, Isabela Gerdes Gyuricza, Isabela Gerdes Gyuricza, Abebe A. Fola, Kevin Wamae, Ashenafi Assefa, Ashenafi Assefa, Karamoko Niaré, Kyaw Thwai, Samuel J. White, William J. Moss, Rhoel R. Dinglasan, Sandrine Eveline Nsango, Christopher B. Tume, Jonathan B. Parr, Jonathan B. Parr, Jonathan B. Parr, Innocent Mbulli Ali, Jeffrey A. Bailey, Jeffrey A. Bailey, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano

“…This assay uses oligonucleotide primers in two pools and a non-proprietary library and barcoding approach.ResultsWe evaluated Pf-SMARRT using control mocked dried blood spots (DBS) at varying levels of parasitemia and a mixture of 3D7 and Dd2 strains at known frequencies, showing the ability to genotype at low parasite density and recall within-sample allele frequencies. …”
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Improving daily reference evapotranspiration forecasts: Designing AI-enabled recurrent neural networks based long short-term memory by Mumtaz Ali, Jesu Vedha Nayahi, Erfan Abdi, Mohammad Ali Ghorbani, Farzan Mohajeri, Aitazaz Ahsan Farooque, Salman Alamery

“…By combining RNNs with LSTM units, models can leverage the strengths of both approaches to improve their ability to process sequential data effectively. This integration allows for better capturing of both short-term and long-term dependencies in the input sequences. …”
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Design of a Wearable Exoskeleton Piano Practice Aid Based on Multi-Domain Mapping and Top-Down Process Model by Qiujian Xu, Meihui Li, Guoqiang Chen, Xiubo Ren, Dan Yang, Junrui Li, Xinran Yuan, Siqi Liu, Miaomiao Yang, Mufan Chen, Bo Wang, Peng Zhang, Huiguo Ma

“…This study designs and develops a wearable exoskeleton piano assistance system for individuals recovering from neurological injuries, aiming to help users regain the ability to perform complex tasks such as playing the piano. …”
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Blood biomarkers to identify patients with different intracranial lesion combinations after traumatic brain injury by Pia Koivikko, Ari J. Katila, Riikka SK. Takala, Iftakher Hossain, Teemu M. Luoto, Rahul Raj, Mari Koivisto, Olli Tenovuo, Kaj Blennow, Peter Hutchinson, Henna-Riikka Maanpää, Mehrbod Mohammadian, Virginia F. Newcombe, Jean-Charles Sanchez, Jussi Tallus, Mark van Gils, Henrik Zetterberg, Jussi P. Posti

“…The results may reflect the severity of TBI but also show that biomarkers have a variable ability to identify patients with combinations of intracranial traumatic lesions in the examined time window.…”
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Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression by Yiting Shao, Yu Du, Zheng Chen, Lei Xiang, Shaoqin Tu, Yi Feng, Yuluan Hou, Xiaoxing Kou, Hong Ai

“…Knockdown of FASN in OSCC-MSCs reduced their adipogenic potential and inhibited their ability to promote OSCC cell proliferation and migration. …”
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Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention by Abdulhakeem Olarewaju Sulyman, Olawale Moshood Aliyu, Emmanuel Oladipo Ajani, Yusuf Folohunsho Abdulkareem, Isaac Ade Afe, Fathia Oluwakemi Abdulyakeen, Halimat Yusuf Lukman, Saheed Sabiu, Karishma Singh, Kuben Naidoo

“…Its therapeutic potential in erectile dysfunction lies in its ability to boost NO production, improving penile blood flow and erection quality. …”
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APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology by Kristine M. Tran, Nellie E. Kwang, Claire A. Butler, Angela Gomez-Arboledas, Shimako Kawauchi, Cassandra Mar, Donna Chao, Rocio A. Barahona, Celia Da Cunha, Kate I. Tsourmas, Zechuan Shi, Shuling Wang, Sherilyn Collins, Amber Walker, Kai-Xuan Shi, Joshua A. Alcantara, Jonathan Neumann, Duc M. Duong, Nicholas T. Seyfried, Andrea J. Tenner, Frank M. LaFerla, Lindsay A. Hohsfield, Vivek Swarup, Grant R. MacGregor, Kim N. Green

“…Conclusions These findings highlight the ability of the ApoeCh variant to modulate microglial responses based on the type of pathology, enhancing DAM reactivity in amyloid models and dampening neuroinflammation to promote protection in tau models. …”
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Elevated Kappa Index in the Absence of Cerebrospinal Fluid IgG Oligoclonal Bands: Contribution of Intrathecal IgM and IgA Synthesis by Krzysztof Smolik, Roberta Bedin, Patrizia Natali, Martina Cardi, Diego Franciotta, Anna Maria Simone, Paolo Immovilli, Mario Santangelo, Matteo Gastaldi, Giulia De Napoli, Francesca Vitetta, Diana Ferraro

“…The main aim of this study was to evaluate the kappa index for its ability to detect the presence of CNS humoral immunity and to associate it with a distinct group of disorders, in the absence of IgG IS/OCBs. …”
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Expedited Colorectal Cancer Detection Through a Dexterous Hybrid CADx System With Enhanced Image Processing and Augmented Polyp Visualization by Akella Subrahmanya Narasimha Raju, K. Venkatesh, Ranjith Kumar Gatla, Marwa M. Eid, Aymen Flah, Zdenek Slanina, Ramy N. R. Ghaly

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Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19 by Juan Antonio Suárez-Cuenca, José Fernando Flores-Zaleta, Leslie Andrea Corona-Rojas, Pablo Guzmán-Rullán, Luis Alfonso Camacho-Barajas, Uzziel Aguilera-Ontiveros, Alberto Melchor-López, Alejandro González-Mora, Perla Marlene Guzmán-Ramírez, Janicia Rodríguez-Solis

“…Conclusion Tomographic extent of lung involvement and the pattern of lung injury are related with coagulopathy severity markers like D-Dimer, and own prognostic clinical ability in ARDS.…”
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Candidate SNP-markers altering TBP binding affinity for promoters of the Y-linked genes CDY2A, SHOX, and ZFY are lowering many indexes of reproductive potential in men by M. P. Ponomarenko, E. B. Sharypova, I. A. Drachkova, L. K. Savinkova, I. V. Chadaeva, D. A. Rasskazov, P. M. Ponomarenko, L. V. Osadchuk, A. V. Osadchuk

“…Reproductive potential is the most important conditional indicator reflecting the ability of individuals in a population to reproduce, survive and develop under optimal environmental conditions. …”
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Exploring the Role of Radiosurgery for Atypical Meningiomas: Addressing Suboptimal Local Control in High-Risk Patients by Sanjeev Sreenivasan, MD, MCh, Salem Najjar, BA, Daniel Ma, MD, Sabrina L. Begley, BS, Yen-Ruh Wuu, MD, Zaker Rana, MD, Emile Gogineni, DO, Michael Schulder, MD, Anuj Goenka, MD

“…Stereotactic radiosurgery (SRS) offers the ability to achieve improved local control (LC) with a low toxicity profile. …”
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Molybdenum Can Regulate the Expression of Molybdase Genes, Affect Molybdase Activity and Metabolites, and Promote the Cell Wall Bio-Synthesis of Tobacco Leaves by Yuan Zhao, Yu Zhang, Kai Zhang, Jiashu Tian, Huanyu Teng, Zicheng Xu, Jiayang Xu, Huifang Shao, Wei Jia

“…Furthermore, the cell walls thickened, increasing the ability of the plant to withstand disturbances. The metabolic network diagrams indicate that Mo regulated galactose metabolism, and arginine and proline acid biosynthesis. …”
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Comparison of the adequacies of the OSCE and vOSCE to assess the competencies required under Brazilian medical curriculum guidelines: a multicenter study by Hervaldo Sampaio Carvalho, Maria do Carmo Barros Melo, Fabiana Maria Kakehasi, Priscila Menezes Ferri Liu, Fernanda Gontijo Minafra Silveira Santos, Ricardo Luiz de Melo Martins, Marilene Vale de Castro Monteiro, Marcelo Esteves Chaves Campos, Roberto Zonato Esteves, Matheus Belloni Torsani, Iolanda de Fátima Lopes Calvo Tiberio, Akihito Inca Atahualpa Urdiales, Andrea Mora De Marco Novellino, Rosiane Viana Zuza Diniz, Helena Ferreira Moura, Maria Alice de Vilhena Toledo, Célia Regina Machado Saldanha, Andrea Pedrosa Ribeiro Alves Oliveira, Patricia Zen Tempski, Itamar de Souza Santos, Milton de Arruda Martins

“…They responded to a questionnaire with the provided Likert scores indicating the ability of the OSCE and vOSCE to assess each type of competency. …”
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Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations by Ayat Kadhi, Ayat Kadhi, Ayat Kadhi, Edward Eid, Michel J. Massaad, Inaam El-Rassy, Dana Maria Khoury, Yutaka Shimomura, Nelly Rubeiz, Mazen Kurban, Mazen Kurban, Mazen Kurban, Georges Nemer, Georges Nemer

“…This was evident from the presence of IL17RA in the patient’s peripheral blood mononuclear cells (PBMCs) and the ability of the mutant IL17RA to dimerize with both wild-type protein and its partners IL17RC and IL17RD. …”
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Cell culture expansion media choice affects secretory, protective and immuno-modulatory features of adipose mesenchymal stromal cell-derived secretomes for orthopaedic applications by Enrico Ragni, Andrea Papait, Michela Maria Taiana, Paola De Luca, Giulio Grieco, Elsa Vertua, Pietro Romele, Cecilia Colombo, Antonietta Rosa Silini, Ornella Parolini, Laura de Girolamo

“…Methods: Immunophenotype and secretory ability at soluble protein and EV-related levels, including embedded miRNAs, were analysed in the secretomes by means of flow cytometry, nanoparticle tracking analysis, high throughput ELISA and qRT-PCR arrays. …”
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The Effects of TMR® Fab 6 on Hamstring Flexibility in Healthy Subjects; An Exploratory Observational Investigation by Richard D. Patterson, Alexander Zettlemoyer, Mary Plackowski, Russell Baker, Scott W. Cheatham, Alan Nasypany

“…Following collection of demographic information and a brief medical history, each participant performed a five minute warm-up on the stationary bike at a moderate intensity (80-90 RPMs) followed immediately by the bilateral performance of the Active Knee Extension Test (AKET) and Passive Straight Leg Raise (PSLR) to assess hamstring muscle length. …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…The themes from group exercise were: (1) monitoring and modification of the online exercise; (2) catering for differing abilities; (3) feeling safe and confident to exercise; (4) progression of fitness; (5) optimal timing in the recovery trajectory; (6) group effect; (7) initial apprehension about exercise group; (8) gauging exercise capabilities; (9) translating exercises into life; and (10) on-demand supplementary videos. …”
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