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12881
Unveiling Silent Atherosclerosis in Type 1 Diabetes: The Role of Glycoprotein and Lipoprotein Lipidomics, and Cardiac Autonomic Neuropathy
Published 2025-01-01“…Stratification by the presence of CAN revealed no impact on the model’s ability to predict subclinical atherosclerosis, underscoring its robustness across different risk subgroups. …”
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12882
Modelling height to crown base using non-parametric methods for mixed forests in China
Published 2025-03-01“…The height to crown base (HCB) of a tree is a vital characteristic that reflects the self-thinning ability of a tree, and it is used to determine the crown size. and predict the crown recession rate. …”
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12883
Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation
Published 2025-01-01“…Mechanistically, sorafenib promoted the effect and fatty acid uptake ability of MDSCs and modulated peroxisome proliferator-activated receptor α (PPARα)-mediated fatty acid oxidation (FAO). …”
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12884
Early Detection of Microvascular Changes in Patients with Diabetes Mellitus without and with Diabetic Retinopathy: Comparison between Different Swept-Source OCT-A Instruments
Published 2019-01-01“…Optical coherence tomography angiography (OCT-A) has recently improved the ability to detect subclinical and early clinically visible microvascular changes occurring in patients with diabetes mellitus (DM). …”
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12885
Targeting ASK1 by CS17919 alleviates kidney‐ and liver‐related diseases in murine models
Published 2025-01-01“…Methods First, we validated the ability of CS17919 to inhibit ASK1 in vitro and then tested the safety profile of CS17919 in cell lines compared with Selonsertib (GS‐4997), a phase III ASK1 inhibitor. …”
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12886
Associations between skeletal muscle phenotype, positional role, and on‐ice performance in elite male ice hockey players
Published 2024-11-01“…On‐ice intermittent exercise capacity, repeated sprint ability, and maximal isometric knee‐extensor torque were also assessed. …”
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12887
Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model
Published 2021-01-01“…Recently, dental pulp-derived mesenchymal stem cells (DP-MSCs) have been attracting more and more attentions in therapeutic applications due to their high proliferation ability, powerful osteogenic differentiation potential, and effective anti-inflammatory effects. …”
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12888
The Isolation of Lead-Tolerant PGPR from Red Clover Soil and Its Role in Promoting the Growth of Alfalfa
Published 2025-01-01“…(strain Y23) exhibited a strong growth-promoting ability in alfalfa, and there was no antagonistic reaction among the three strains, enabling their coexistence. …”
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12889
Evaluation of a strategy for tumor-initiating stem cell eradication in primary human glioblastoma cultures as a model
Published 2018-11-01“…The key elements of the strategy were the following indicator results: (1) evaluation of the presence of tumor-initiating stem cells in a population of cells from analyzed cultures by their ability to internalize double-stranded labeled DNA (TAMRA+ cells); (2) determination of the reference time points of the repair cycle of DNA interstrand cross-links induced by cross-linking cytostatic mitomycin C; (3) evaluation of cell cycle synchronization; (4) determination of the time (day after therapy initiation) when TAMRA+ cells were synchronously present in phase G1/S of the cell cycle, sensitive to the therapy; and (5) establishment of the TAMRA+ (tumor-initiating stem cells) eradication schedule. …”
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12890
The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium
Published 2025-02-01“…Our results indicate that the absence of the arcB gene significantly affects the ability of S. Typhimurium to grow under HOCl stress. …”
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12891
The features of Tat protein of human immunodeficiency virus type 1 (Retroviridae: <i>Lentivirus: Lentivirus humimdef1</i>) non-A6 variants, characteristic for the Russian Federatio...
Published 2024-12-01“…Tat protein is a trans-activator of HIV-1 genome transcription, with additional functions including the ability to induce the chronic inflammatory process. …”
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12892
Density functional theory calculation for understanding the roles of biochar in immobilizing exchangeable Al3 + and enhancing soil quality in acidic soils
Published 2025-01-01“…Additionally, we employed density functional theory (DFT) calculations to elucidate the mechanisms underlying biochar's ability to immobilize exchangeable Al3+. Furthermore, we conducted 15N double-labeled incubation experiments to examine the impact of biochar on soil nitrogen (N) transformation in acidic conditions. …”
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12893
In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic...
Published 2019-01-01“…In human studies, the ability to track transplanted cells has been limited to labeling with radioisotopes and tracking using nuclear imaging. …”
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12894
Accuracy of Established Prognostic Staging Systems for Cardiac Transthyretin Amyloidosis in the Tafamidis Era
Published 2025-02-01“…The staging systems’ ability to identify subgroups with distinct overall survival was assessed using Kaplan-Meier analyses and pairwise log-rank tests. …”
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12895
Cooperation Between <i>Rhodococcus qinshengii</i> and <i>Rhodococcus erythropolis</i> for Carbendazim Degradation
Published 2024-12-01“…Metabolomic analysis by HPLC and LC-MS showed that both strains have the ability to metabolize carbendazim. <i>R. qingshengii</i> RC1 converts carbendazim to 2-AB, the first degradation intermediary, while <i>R. erythropolis</i> RC9 metabolizes the fungicide to its mineralization, probably because <i>R. qingshengii</i> RC1 lacks the <i>hdx</i> gene coding for 2-AB hydroxylase. …”
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12896
Association Between Nontraditional Lipid Profiles and the Risk of Type 2 Diabetes Mellitus in Chinese Adults With Hypertension: Findings From the China Hypertension Registry Study
Published 2025-01-01“…Additionally, the study demonstrated that AIP had a superior ability to identify T2DM. Subgroup analyses indicated that the relationship between AIP and Non‐HDL‐C with T2DM was more significant in the lighter weight population. …”
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12897
Perioperative nursing management of transcatheter edge-to-edge repair (经导管二尖瓣缘对缘修复术围手术期护理)
Published 2024-12-01“…The comprehensive interventions including enhanced recovery after surgery, respiratory exercise, pain control, catheter maintenance and standard health education before discharge were carried out to relieve symptoms of heart failure, improve self-care ability and quality of life of patients after transcatheter edge-to-edge repair. …”
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12898
RADAR-AD: assessment of multiple remote monitoring technologies for early detection of Alzheimer’s disease
Published 2025-01-01“…In addition, our findings show that the Amsterdam iADL questionnaire has high discriminatory abilities. Conclusions RMTs show promise in AD detection already in the prodromal stage. …”
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12899
PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients
Published 2025-01-01“…Two SDE genes achieved excellent discrimination ability: NCAPG had an AUROC of 0.908, NHLRC1 of 0.879, and a logistic regression model with these two genes of 0.955.ConclusionA pre-treatment gene expression signature in PBMCs was associated with liver fibrosis regression (LSMred>50%) after achieving HCV clearing with HCV therapy in HIV/HCV-coinfected patients, where two SDE genes (NCAPG and NHLRC1) showed the greatest predictive capacity, which could be used as a noninvasive marker of liver fibrosis regression.…”
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12900
Development of a Multi-Sensor Mobile Device for Urban Air Quality Monitoring at the Street Corner: The SMILE Project
Published 2025-01-01“…Outdoor experiments were conducted in the city of Marseille to validate the efficiency of the AQM device and assess its ability to provide street-level air quality data. …”
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