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  1. 12501

    Association of Immune Nutrition Indices with the Risk of All-Cause Mortality and Cardiovascular Mortality in Patients with Heart Failure in the NHANES (1999–2018) by Feifei Zhang, Yuetao Xie, Litian Liu, Huiliang Liu, Ohua Feng, Yingxiao Li, Yi Dang

    Published 2025-01-01
    “…A time-dependent receiver operating characteristic curve analysis was conducted to assess the predictive ability. …”
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  2. 12502

    Staphylococcus aureus nt5 gene mutation through CRISPR RNA-guided base editing weakens bacterial virulence and immune evasion by Xinpeng Liu, Lan Huang, Yang Ye, Haiyi Wang, Min Tang, Fuqiang He, Zijing Xia, Shi Deng, Peng Zhang, Ruiwu Dai, Shufang Liang

    Published 2025-12-01
    “…Herein, to reveal nt5 gene role in drug resistance and infection ability of S. aureus, we performed nt5C166T gene mutation using a clustered regulatory interspaced short palindromic repeat ribonucleic acid (RNA)-guided base editing system to investigate the lose-of-function of NT5 protein. …”
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  3. 12503

    Role of YAP/TAZ in bone diseases: A transductor from mechanics to biology by Xin Chen, Xing Ji, Zhaobai Lao, Bin Pan, Yu Qian, Wanlei Yang

    Published 2025-03-01
    “…Emerging research highlights bone cells' ability to sense various mechanical stimuli and relay these signals intracellularly. …”
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  4. 12504

    Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells by K. S. Young, G. R. Hancock, E. C. Fink, A. Zigrossi, B. Flowers, D. A. Cooper, V. T. Nguyen, M. C. Martinez, K. S. Mon, M. Bosland, D. R. Zak, A. P. Runde, M. N. Sharifi, I. Kastrati, D. D. L. Minh, S. Kregel, Sean W. Fanning

    Published 2025-01-01
    “…It enables endocrine therapy resistance by superceding intrinsic structural-energetic gatekeepers of ER hormone-dependence, it enhances metastatic burden by enabling neomorphic ER-dependent transcriptional programs, and it resists SERM and SERD inhibiton by reducing their binding affinities and abilities to antagonize transcriptional coregulator binding. …”
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  5. 12505

    Enhancement of Cognitive Benefits and Anti-Anxiety Effects of <i>Phytolacca americana</i> Fruits in a Zebrafish (<i>Danio rerio</i>) Model of Scopolamine-Induced Memory Impairment by Lucia-Florina Popovici, Ion Brinza, Florentina Gatea, Georgiana Ileana Badea, Emanuel Vamanu, Simona Oancea, Lucian Hritcu

    Published 2025-01-01
    “…Furthermore, these extracts demonstrated the ability to mitigate cholinergic deficits by inhibiting AChE activity and supporting antioxidant defense mechanisms through increased activity of antioxidant enzymes and reduced lipid and protein peroxidation. …”
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  6. 12506

    Wetland elevation change following beneficial use of dredged material nourishment by Brian D. Harris, Aleksandra Ostojic, Lenore P. Tedesco, Keith VanDerSys, Susan Bailey, Justin L. Shawler, Navid H. Jafari, Monica Chasten

    Published 2025-02-01
    “…This investigation allowed for a comprehensive examination of geotechnical modeling methods for planning wetland nourishments, including predicting the ability to keep pace with sea level rise. Ultimately, the two BUDM nourishments offset the effects of SLR by approximately 18-28 years.…”
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  7. 12507

    Predictive biomarkers for cardiometabolic risk in postmenopausal women: insights into visfatin, adropin, and adiponectin by Anna Maria Cybulska, Daria Schneider-Matyka, Ireneusz Walaszek, Mariusz Panczyk, Dorota Ćwiek, Anna Lubkowska, Elżbieta Grochans, Kamila Rachubińska, Katarzyna Malewicz, Mariusz Chabowski, Mariusz Chabowski

    Published 2025-02-01
    “…Visfatin is known for its pro-inflammatory properties and its ability to modulate insulin resistance. Adropin is involved in energy homeostasis and metabolic health, while adiponectin has anti-inflammatory and insulin-sensitizing effects. …”
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  8. 12508

    A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor by Rebecca L. Brouillette, Christine E. Mona, Michael Desgagné, Malihe Hassanzedeh, Émile Breault, Frédérique Lussier, Karine Belleville, Jean-Michel Longpré, Michel Grandbois, Pierre-Luc Boudreault, Élie Besserer-Offroy, Philippe Sarret

    Published 2025-02-01
    “…Here, using BRET2-based biosensors, we demonstrated the ability of ARIP to inhibit agonist-induced β-arrestin recruitment on a series of 7TMRs that includes both stable and transient β-arrestin binders, with efficiencies that depend on receptor type. …”
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  9. 12509

    Breeding for Heat Tolerant Aromatic Rice Varieties and Identification of Novel QTL Regions Associated with Heat Tolerance During Reproductive Phase by QTL-Seq by Surangkana Chimthai, Sulaiman Cheabu, Wanchana Aesomnuk, Siriphat Ruengphayak, Siwaret Arikit, Apichart Vanavichit, Chanate Malumpong

    Published 2025-01-01
    “…Therefore, our objective was to develop heat-tolerant aromatic rice varieties using the pedigree method, focusing on selecting for seed-setting ability under extremely high temperatures along with the use of single nucleotide polymorphism/insertion and deletion (SNP/InDel) markers to improve aromatic properties and grain quality. …”
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  10. 12510

    Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

    Published 2025-01-01
    “…In aHUS, FHAAs target the C-terminus, thereby impacting FH ability to recognize cell surfaces. In C3G, in contrast, FHAAs often target the N-terminus, generating an acquired functional FH deficiency. …”
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  11. 12511

    Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

    Published 2024-12-01
    “…This alarming trend threatens the country’s ability to provide equitable healthcare. Objective This study investigated the patterns and determinants of migration among doctors and dentists who graduated from the University of Benin, Nigeria, 15 years ago. …”
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  12. 12512

    Intracranial aneurysm instability prediction model based on 4D-Flow MRI and HR-MRI by Fei Peng, Jiaxiang Xia, Fandong Zhang, Shiyu Lu, Hao Wang, Jiashu Li, Xinmin Liu, Yao Zhong, Jiahuan Guo, Yonghong Duan, Binbin Sui, Chuyang Ye, Yi Ju, Shuai Kang, Yizhou Yu, Xin Feng, Xingquan Zhao, Rui Li, Aihua Liu

    Published 2025-01-01
    “…We introduce a specialized ensemble learning framework, termed the Hybrid Model, which synergistically combines two heterogeneous base learning algorithms: 4D-Flow logistic regression (4D-Flow-LR) and Multi-crop Attention Branch Network (MicroAB-Net). The ability of the hybrid model to predict aneurysm instability was compared with baseline models: PHASES (population, hypertension, age, size, earlier rupture, and site) LR, ELAPSS (earlier subarachnoid hemorrhage, location, age, population, size, and shape) LR, aneurysm wall enhancement (AWE) LR, and Radiomics using the area under the curve (AUC) with Delong's test. …”
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  13. 12513

    Predictive method for poultry carcass visceral dimensions using 3D point cloud and Genetic Algorithm-based wavelet neural network by Zhengwei Zhu, Yan Chen, Lu Cai, Jinzhou Yang, Ke Wen, Jingjing Bao, Zhigang Hu, Dandan Fu

    Published 2025-01-01
    “…Finally, in order to verify the generalizability of the method, generalizability experiments were conducted on different breeds of poultry, which proved that the method of this study had superior generalizability ability. In the comparative analysis of the six models, the MAPE and RMSE of the GA-WNN model for the prediction of the three visceral dimensions were the lowest except for the RMSE for the prediction of visceral length. …”
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  14. 12514

    Hybrid Prophet-NAR Model for Short-Term Electricity Load Forecasting by Winita Sulandari, Yudho Yudhanto, Etik Zukhronah, Isnandar Slamet, Hilman Ferdinandus Pardede, Paulo Canas Rodrigues, Muhammad Hisyam Lee

    Published 2025-01-01
    “…The proposed PropNAR integrated the strengths of the Prophet model in capturing deterministic structures, such as trends, seasonality, and holiday effects with the NAR model&#x2019;s ability to handle nonlinear stochastic relationships. …”
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  15. 12515

    Host-symbiont-gene phylogenetic reconciliation by Menet, Hugo, Trung, Alexia Nguyen, Daubin, Vincent, Tannier, Eric

    Published 2023-05-01
    “…We evaluate the capacity of our method on simulated data, notably its capacity to infer horizontal gene transfers, and its ability to detect hostsymbiont co-evolution by comparing host/symbiont/gene and symbiont/gene models based on their estimated likelihoods. …”
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  16. 12516

    Use of Relay Method for Enhancing Comb Construction by <i>Apis cerana cerana</i> Utilizing <i>Apis mellifera ligustica</i> by Shunhua Yang, Shanglun Ge, Yiqiu Liu, Danyin Zhou, Xueyang Gong, Kun Dong

    Published 2025-01-01
    “…Italian honey bees (IHBs, <i>Apis mellifera ligustica</i>) exhibit superior comb-building abilities compared with Chinese honey bees (CHBs, <i>Apis cerana cerana</i>), which often fail to fully utilize wax foundations, resulting in incomplete comb structures. …”
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  17. 12517

    Comprehensive phenotypic analysis of multiple gene deletions of α-glucan synthase and Crh-transglycosylase gene families in Aspergillus niger highlighting the versatility of the fu... by Katharina J. Ost, Mark Arentshorst, Bruno M. Moerschbacher, Mareike E. Dirks-Hofmeister, Arthur F.J. Ram

    Published 2025-06-01
    “…These observations underscore the ability of fungal cells to adapt and secure cell wall integrity, even when two entire cell wall protein-encoding gene families are missing.…”
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  18. 12518

    Development of Attenuated Total Reflectance Mid-Infrared (ATR-MIR) and Near-Infrared (NIR) Spectroscopy for the Determination of Resistant Starch Content in Wheat Grains by Rong Wang, Xia Wei, Hongpan Wang, Linshu Zhao, Cengli Zeng, Bingrui Wang, Wenying Zhang, Luxiang Liu, Yanhao Xu

    Published 2021-01-01
    “…The validation of the developed best NIR and ATR-MIR calibration models showed that the ATR-MIR best calibration model has a better RS prediction ability than the NIR best calibration model. Two high grain RS content wheat mutants were screened out by the ATR-MIR best calibration model from the wheat mutant library. …”
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  19. 12519

    A Prospective Randomized Study for Comparison of Modified Proximal Femoral Plate with Dynamic Hip Screw System by Jitendra Wadhwani, Ramchander Siwach, Himanshu Bansal, Roop Singh, Pradeep Kamboj, Hemant More

    Published 2024-06-01
    “…It is an angular stable construct with the ability to achieve compression across the fracture site. …”
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  20. 12520

    Highly Sensitive Non-Dispersive Infrared Gas Sensor with Innovative Application for Monitoring Carbon Dioxide Emissions from Lithium-Ion Battery Thermal Runaway by Liang Luo, Jianwei Chen, Aisn Gioronara Hui, Rongzhen Liu, Yao Zhou, Haitong Liang, Ziyuan Wang, Haosu Luo, Fei Fang

    Published 2024-12-01
    “…Notably, carbon dioxide (CO<sub>2</sub>) gas sensors are emphasized for their ability to enhance early-warning systems, facilitating the timely detection of potential issues and, in turn, improving the overall safety standards of electric vehicles. …”
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