Effects of Ginsenoside Rg1 Regulating Wnt/β-Catenin Signaling on Neural Stem Cells to Delay Brain Senescence by Yue Xiang, Shun-he Wang, Lu Wang, Zi-ling Wang, Hui Yao, Lin-bo Chen, Ya-ping Wang

“…The following indicators were detected: (1) NSC culture identification, (2) the effect of LiCl on the proliferation and survival rate of NSCs, (3) the effect of ginsenoside Rg1 on the proliferation and survival of NSCs, (4) the growth of NSCs in each group observed by an optical microscope, (5) the cell cycle of each group detected by flow cytometry, (6) the proliferative ability of each group detected by BrdU, (7) the fluorescence intensity of Nestin and Sox2 of NSCs in each group observed by a fluorescence microscope, (8) the positive rate of senescence staining analyzed by SA-β-Gal staining, (9) the localization of β-catenin in NSCs observed by laser confocal microscopy, and (10) the changes of the Wnt/β-catenin pathway-related proteins in each group detected by Western blotting. …”
Get full text

The Effectiveness of an Anoxic-Oxic-Anoxic-Oxic Sequencing Batch Reactor System (A2/O2-SBR) to Treat Electroplating Wastewater and the Bacterial Community within the System by Tanta Suriyawong, Sasidhorn Buddhawong, Thanit Swasdisevi, Suntud Sirianuntapiboon

“…The anoxic period and bacterial community have significantly demonstrated the ability to remove Zn2+ and Cd2+ for effective treatment of EPWW.…”
Get full text

Tropical cyclone intensity estimation based on YOLO-NAS using satellite images in real time by Priyanka Nandal, Prerna Mann, Navdeep Bohra, Ghadah Aldehim, Asma Abbas Hassan Elnour, Randa Allafi

“…The meteorological significance of this work lies in its ability to offer a reliable, real-time tool for cyclone intensity prediction, which could be integrated into operational weather forecasting systems. …”
Get full text

GS-DTA: integrating graph and sequence models for predicting drug-target binding affinity by Junwei Luo, Ziguang Zhu, Zhenhan Xu, Chuanle Xiao, Jingjing Wei, Jiquan Shen

“…GATv2-GCN enhances the model’s ability to focus on important nodes by assigning dynamic attention scores, which improves the learning of the graph structure’s intricate patterns. …”
Get full text

Managing ADHD Symptoms in Children Through the Use of Various Technology-Driven Serious Games: A Systematic Review by Aikaterini Doulou, Pantelis Pergantis, Athanasios Drigas, Charalampos Skianis

“…Children with attention deficit hyperactivity disorder (ADHD) frequently experience impairments in a range of abilities. Due to their poor attention and concentration, they find it challenging to stay focused when learning. …”
Get full text

Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells by Yan Li, Jingping Ge, Yuanyuan Yin, Ruowen Yang, Jie Kong, Jianping Gu

“…Furthermore, silencing of miR-206 suppressed the autophagy of EPCs via upregulating GJA1. miR-206 knockdown repressed thrombus formation, enhanced the homing ability of EPCs to the thrombosis site, and facilitated thrombus resolution in DVT mouse models. …”
Get full text

Molecular Mechanism During Mycelium Subculture Degeneration of <i>Volvariella volvacea</i> by Lidan Feng, Lujuan Wang, Yuanxi Lei, Jie Li, Fengyun Zhao

“…The results showed that as the number of subcultures increased, the diameter of the mycelium and biological efficiency gradually decreased; in addition, the time in which the primordium formed increased and the production cycle was lengthened, while strains M4 and M5 lacked the ability to produce fruiting bodies. There were 245 differentially expressed genes between the M1–M5 and M0 strains, while the highest number of differentially expressed genes was between M3 and M0, at 1439; the smallest number of differentially expressed genes was between M2 and M0, at 959. …”
Get full text

Development of metastasis and survival prediction model of luminal and non-luminal breast cancer with weakly supervised learning based on pathomics by Hui Liu, Linlin Ying, Xing Song, Xueping Xiang, Shumei Wei

“…Result Our results show that the Inception_v3 model shows a particularly robust patch recognition ability for estrogen receptor (ER) recognition. Our pathological model shows high accuracy in predicting tumor regions. …”
Get full text

Design and Test of a Cone Dielectric Elastomer Actuator Driving Hopping Robot by Yunguang Luan, Huaming Wang, Ling Zhou, Haichao Song

“…Dielectric elastomer actuators (DEAs) are increasingly recognized for their potential in robotic applications due to their ability to undergo significant deformation when subjected to an electric field. …”
Get full text

Heterologous Expression and Adaptive Evolution of ε-Poly-lysine Synthase Gene in <i>Corynebacterium glutamicum</i> by Long Pan, Yihang Chen, Aimei Liao, Yinchen Hou, Jihong Huang

“…<i>Corynebacterium glutamicum</i> (<i>C. glutamicum</i>) is a food safety strain that is widely used in the fermentation industry to produce various amino acids. Its ability to produce high amounts of L-lysine can provide sufficient precursor substances for the synthesis of ε-PL, making it an ideal strain for the heterologous expression of ε-PL synthase genes (<i>pls</i>). …”
Get full text

Test Performance of Plastic Waste Shredder Machine and Analyze the Quality of the Shredded Plastic Product Using the Taguchi Method by Adam - Kamil, Hendra Hendra, Sidik Susilo, Erny Listijorini, Hernadewita Hernadewita

“…The important thing in plastic processing machines is the ability of plastic processing machines to produce products according to consumer desires. …”
Get full text

Study of fertility and cytogenetic variability in androgenic plants (R0 and R1) of alloplasmic introgression lines of common wheat by T. S. Osadchaya, N. V. Trubacheeva, L. A. Kravtsova, I. A. Belan, L. P. Rosseeva, L. A. Pershina

“…Differences between the lines in the ability for androgenesis and in the level of fertility in R0 and R1 have been revealed. …”
Get full text

Effects of Error Modulation-Based Visual and Haptic Feedback Fusion Strategies on Motor Learning and Motivation by Jingyan Meng, Na Li, Yang Hu, Dazheng Zhao, Guoning Li, Jingyan Hu, Tao Song, Yehao Ma, Rongzhen Fu, Guokun Zuo, Liang Tao, Min Tang, Yunfeng Liu, Changcheng Shi

“…The VRHA fusion strategy significantly improved the subjects’ motor learning and transfer ability, decreased muscle activation, and increased motor learning motivation. …”
Get full text

Risk prediction models for post-intensive care syndrome of ICU discharged patients: A systematic review by Pengfei Yang, Fu Yang, Qi Wang, Fang Fang, Qian Yu, Rui Tai

“…Results: This systematic review included a total of 16 studies, comprising two cognitive impairment studies, four psychological impairment studies, eight physiological impairment studies, and two studies on all three domains. The discriminative ability of prediction models measured by area under the receiver operating characteristic curve was 0.68–0.90. …”
Get full text

Identification of a New Prognostic Risk Signature of Clear Cell Renal Cell Carcinoma Based on N6-Methyladenosine RNA Methylation Regulators by Yan Zhang, Yao Yao, Xiaochen Qi, Jianyi Li, Meihong Liu, Xiangyu Che, Yingkun Xu, Guangzhen Wu

“…An ROC curve, univariate Cox regression analysis, and multivariate Cox regression analysis were used to verify this risk signature’s predictive ability. Then, we internally validated this signature by random sampling. …”
Get full text

Sex differences in anaerobic performance in CrossFit® athletes: a comparison of three different all-out tests by Tomás Ponce-García, Jerónimo García-Romero, Laura Carrasco-Fernández, Alejandro Castillo-Domínguez, Javier Benítez-Porres

“…It is associated with the ability to perform explosive actions and the capacity for rapid recovery between repeated efforts. …”
Get full text

The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. by Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta

“…Herein, film-formulated RC-101 was assessed for its antiviral activity in vitro, safety in vivo, retention in the cervix and vagina, and ability to remain active against HIV-1 and SHIV after intravaginal application in macaques.…”
Get full text

Microbiological And Physicochemical Analyses Of Oil Contaminated Soil From Major Motor Mechanic Workshops In Benin City Metropolis,Edo State, Nigeria by FO Ekhaise, J Nkwelle

“…The ability of microorganisms to utilize used oil in contaminated soil from some selected major mechanic workshops in Benin City metropolis as sole source of carbon and energy was studied. …”
Get full text

Isolation and Antifungal Susceptibility of Candida spp. from Pediatric Patients in Kurdistan of Iraq by Mohammed Salah Bahi, Khattab Ahmed Mustafa Shekhany

“…Candida species are considered the most common opportunistic human fungal pathogen due to the presence of various virulence factors, including its ability to form a biofilm that aids in oral candidiasis. …”
Get full text

Prevalence and Intensity of Intestinal Helminth Infections in Preschool Pupils in Lugari Subcounty, Kakamega County, Kenya by Daniel Kevin Werunga, Elizabeth Nanjala Omukunda, Jackson Cheruiyot Korir

“…Intestinal helminths cause anaemia, malnutrition, indigestion disorders, retarded growth, and low mental abilities in pupils. About 1.5 billion are infected globally. …”
Get full text