Exercise-Intervened Circulating Extracellular Vesicles Alleviate Oxidative Stress in Cerebral Microvascular Endothelial Cells Under Hypertensive Plus Hypoxic Conditions by Smara Sigdel, Shuzhen Chen, Gideon Udoh, Jinju Wang

“…The functions of cEVs were assessed in an Angiotensin II (Ang II) plus hypoxia-injured cerebral microvascular endothelial cell (mBMEC) injury model. Cellular migration ability and oxidative stress were evaluated. We found that treadmill exercise stimulated cEV release, and ET-cEVs were more prone to be internalized by mBMECs. …”
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Long-Term Environmental Enrichment Relieves Dysfunctional Cognition and Synaptic Protein Levels Induced by Prenatal Inflammation in Older CD-1 Mice by Zhe-Zhe Zhang, Li-Ping Zeng, Jing Chen, Yong-Fang Wu, Ya-Tao Wang, Lan Xia, Qi-Gang Yang, Fang Wang, Gui-Hai Chen

“…Analysis revealed that at 15 months of age, the control mice experienced a reduction in cognitive ability and elevated expression levels of Arc and Syt1 genes when compared to control mice at 3 months of age. …”
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The Effect of a 12-Week Plyometric and Tabata Training Program with Three Weekly Sessions on Cardiovascular Efficiency in Elite Soccer Players by Nidhin Muthrathiparambil Narayanan, Kayambu Sundar, Nirmal Michael Salvi, Yashpal, Debajit Karmakar, Sohom Saha, Bekir Erhan Orhan, Farjana Akter Boby, Yuni Astuti

“…In conclusion, the implementation of a plyometric and Tabata training program has been found to produce significant improvements in cardiovascular efficiency in elite soccer players, making them valuable preseason conditioning strategies to enhance endurance, performance, and overall athletic abilities. …”
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How health literacy relates to venous leg ulcer healing: A scoping review. by Ayoub Bouguettaya, Georgina Gethin, Sebastian Probst, Jane Sixsmith, Victoria Team, Carolina Weller

“…<h4>Background</h4>The level of personal health literacy of patients with venous leg ulcers is likely to affect their ability to self-manage their condition impacting on their adherence to treatment and influences healing and recovery outcomes.…”
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Phenotypic Definition of the Progenitor Cells with Erythroid Differentiation Potential Present in Human Adult Blood by Valentina Tirelli, Barbara Ghinassi, Anna Rita Migliaccio, Carolyn Whitsett, Francesca Masiello, Massimo Sanchez, Giovanni Migliaccio

“…To clarify the phenotype of AB HPC which generate EBs in these cultures, flow cytometric profiling for CD34/CD36 expression, followed by isolation and functional characterization (colony-forming-ability in semisolid-media and fold-increase in HEMA) were performed. …”
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Development of Predictive Models for Progression from Diabetic Kidney Disease to End-Stage Renal Disease in Type 2 Diabetes Mellitus: A Retrospective Cohort Study by Hu H, Mu X, Zhao S, Yang M, Zhou H

“…Among 85 patients with biopsy-proven diabetic DKD, the combined prognostic model integrating KFRE, interstitial fibrosis and tubular atrophy (IFTA), SII and BMI demonstrated enhanced predictive ability at 5 years. The developed models offer improved accuracy over existing methods by incorporating renal pathology and novel inflammatory indices, making them more applicable in clinical settings.Conclusion: The predictive model proved to be effective in assessing the progression of DKD to ESRD. …”
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Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression by Hao Hua, Yazu Deng, Dijie Zheng, Changhao Wu, Liwen Chen, Binbin Shi, Zhiwei He, Chao Yu

“…CircHIF-1α knockdown induces cellular senescence and suppresses PC proliferation in vitro experiments. The ability of circHIF-1α knockdown to suppress the progression of PC cells was further confirmed in vivo experiments. …”
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Key wound healing genes as diagnostic biomarkers and therapeutic targets in uterine corpus endometrial carcinoma: an integrated in silico and in vitro study by Fuchuan Jiang, Sajjad Ahmad, Sadia kanwal, Yasir Hameed, Qian Tang

“…Overexpression studies in UCEC cell lines demonstrated that CD44 and MMP2 reduce proliferative ability while enhancing migration and wound healing. …”
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Predicting breast cancer recurrence using deep learning by Deepa Kumari, Mutyala Venkata Sai Subhash Naidu, Subhrakanta Panda, Jabez Christopher

“…The BCR-HDL framework’s unique contributions include its ability to predict not only diagnostic outcomes but also prognostic and recurrence timing, offering a comprehensive solution for breast cancer management. …”
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Lebanese Cannabis sativa L. extract protects from cisplatin-induced nephrotoxicity in mice by inhibiting podocytes apoptosis by Alia Khalil, Sahar Al Toufaily, Wassim Shebaby, Marissa El Hage, Dima Mroue, Wissam Faour, Mohamad Mroueh

“…In addition, in vitro scratch assay demonstrated the ability of COE to promote and restore the migratory capacity of podocytes in cisplatin-treated cells. …”
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Identification of new genes regulating nodule development in Medicago truncatula: an in-silico approach by Mahboobeh Azarakhsh, Sara Eslami, Maryam Moghadas, Zahra Ataei

“…Among plants, legumes have the ability to fix nitrogen through symbiotic interaction with a specific group of bacteria called rhizobia. …”
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Hepatoprotective potential of Chrysin in a rat model of isoniazid- and rifampicin-induced hepatic injury: suppression of matrix metalloproteinase and transforming growth factor β by Deepa Mandlik, Akhilesh Tokey, Rohit Lokhande, Yash Dagadu, Heena Choudhary, Satish Mandlik

“…Abstract Background The ability of Chrysin (CHY) to scavenge free radicals has been widely explored. …”
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Lysosome-related proteins may have changes in the urinary exosomes of patients with acute gout attack by Jitu Wang, Na Liu, Mei Hu, Man Zhang

“…The ROC analysis showed that CTSZ, AP1B1 and LAMP2 had a strong ability to predict acute gout attack, with AUC of 0.826, 0.847 and 0.882, respectively. …”
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HISS: Snakemake-based workflows for performing SMRT-RenSeq assembly, AgRenSeq and dRenSeq for the discovery of novel plant disease resistance genes by Thomas M. Adams, Moray Smith, Yuhan Wang, Lynn H. Brown, Micha M. Bayer, Ingo Hein

“…This makes reproducibility and version control a challenge and limits the ability to perform these analyses to those with bioinformatics expertise. …”
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Anaemia in the Hospitalized Elderly in Tanzania: Prevalence, Severity, and Micronutrient Deficiency Status by Clara Chamba, Ahlam Nasser, William F. Mawalla, Upendo Masamu, Neema Budodi Lubuva, Erius Tebuka, Pius Magesa

“…Anaemia exhorts negative consequences to functional ability of elderly patients, both physically and cognitively. …”
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INTEGRATION OF INTRADISCIPLINARY TOPICS AND GEOGRAPHY IN THE TEACHING PROCESS OF TECHNOLOGY by M. S Kazimov

“…Thanks to the integrated teaching of Technology and Geography, it is possible for the students to learn the subject comprehensively and much better because integration creates conditions for the development of logical thinking and the formation of ability of independent thinking of students. Moreover, integrative teaching of subjects contributes to the build close relationship between the subjects and themes which have a positive impact on the creation of a dialogue and mutual understanding between teachers and students. …”
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Investigating the Expression of c-Myc and BIRC5 in TRAIL and PBOX-15 treated Metastatic Prostate Cancer Cells by Corinne Kai Leng Chew, Hannah O'Toole, Daniela M Zisterer, Seema M. Nathwani, Jade K. Pollock

“…PBOX-15 presented an ability to sensitise cells to the effects of TRAIL, thus provide insight in potential application of the combination for metastatic prostate cancer.…”
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Hop to It! The Relationship Between Hop Tests and The Anterior Cruciate Ligament – Return to Sport Index After Anterior Cruciate Ligament Reconstruction in NCAA Division 1 Collegia... by Michael Zarro, Madelyn Dickman, Timothy Hulett, Robert Rowland, Derrick Larkins, Jeffrey Taylor, Christa Nelson

“…# Background Outcomes after anterior cruciate ligament reconstruction (ACLR) may not be optimal, with poor physical and psychological function potentially affecting return to sport (RTS) ability. Understanding the relationship between commonly used hop tests and the Anterior Cruciate Ligament -- Return to Sport Index (ACL-RSI) may improve rehabilitation strategies and optimize patient outcomes…”
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Detection of Vertical Root Fractures Using Cone-Beam Computed Tomography in the Presence and Absence of Gutta-Percha by Ehsan Hekmatian, Mitra Karbasi kheir, Hossein Fathollahzade, Mahnaz Sheikhi

“…The intracanal filling materials such as gutta-percha reduce the diagnostic ability of vertical root fractures. Hence, it is recommended to remove those materials from root canals before imaging to improve the diagnostic potential of CBCT.…”
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Cultural validation of the Addenbrooke’s Cognitive Examination Version III Urdu for the British Urdu-speaking population: a qualitative assessment using cognitive interviewing by Nadine Mirza, Maria Panagioti, Waquas Waheed

“…Across 19 ACE-III Urdu items, 7 required changes based on participant feedback: item 5a: fluency; items 6, 18 and 19: memory; items 12 and 13: language; and item 17: visuospatial abilities.The need for some of these changes was realised after 21 participants, due to persistently reoccurring issues, and these were applied before the last four participants. …”
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