Insulin Treatment Perception and Factors affecting the Acceptance in Type 2 Diabetes Mellitus Patients attending a Specialist Clinic in Ilorin, Nigeria by Olalekan A. Agede, John Kola Olarinoye, James Ayodele Ogunmodede, Nasiru Sanni, Matthew Olumuyiwa Bojuwoye, Christopher Muyiwa Opeyemi, Mary Olufunmilayo Ologe, Dapo S Oyedepo

“…Some insulin-experienced patients had positive perceptions of insulin, like their belief in insulin’s health benefits (p = 0.001) and ability to control blood glucose (p = 0.048). Insulin-naive individuals exhibited more negative attitudes toward insulin, emphasizing the need for targeted interventions and patients’ health education. …”
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Efficient recovery of Ce(III) ions from acidic solutions using oxalic acid crosslinked chitosan by Tabtila Okta Rinila, Soon Kong Yong, Waheeba Ahmed Al-Amrani, Agustono Wibowo, Nurul Filzah Ghazali, Murat Yılmaz, Faiz Bukhari Mohd Suah, Megat Ahmad Kamal Megat Hanafiah

“…The maximal adsorptive ability for Ce(III) ions was ascertained to be 408.71 mg g−1 at optimum investigational settings based on the Langmuir equation. …”
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Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes by Ali Tawbeh, Catherine Gondcaille, Fatima-Ezzahra Saih, Quentin Raas, Damien Loichot, Yannick Hamon, Céline Keime, Alexandre Benani, Francesca Di Cara, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Stéphane Savary

“…Furthermore, treated neurons exhibited a reduction in cell complexity and an increased ability to secrete neuropeptides. These findings demonstrate that peroxisomal impairments in microglia exacerbate inflammatory response and ROS/NO production, affecting the survival of neurons and oligodendrocytes, as well as neuronal morphology and function. …”
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Exploring precision therapeutics: computational design of antisense oligonucleotides targeting AXL gene transcripts in multiple sclerosis treatment management by Bhargav Shreevatsa, Bhargav Shreevatsa, Abhigna Nagaraj, Chandan Dharmashekar, Anisha Jain, Bhavana Harendra, Siddesh V. Siddalingegowda, Haneen A. Al-Mazroua, Sheikh F. Ahmad, Shashanka K. Prasad, Chandrashekar Srinivasa, Chandan Shivamallu, Shiva Prasad Kollur

“…To investigate ASO-mRNA interactions and gauge their ability to alter AXL expression, Molecular Docking was performed. …”
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Interactions of Self-Assembled <i>Bletilla Striata</i> Polysaccharide Nanoparticles with Bovine Serum Albumin and Biodistribution of Its Docetaxel-Loaded Nanoparticles by Guangyuan Zhang, Jin Qiao, Xin Liu, Yuran Liu, Ji Wu, Long Huang, Danyang Ji, Qingxiang Guan

“…Drug state, cytotoxicity, and histological studies were carried out. The affinity ability of bovine serum albumin (BSA) and the BSPs-SA nanoparticles was also characterized utilizing ultraviolet and fluorescence spectroscopy. …”
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RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models by Yingqi Lin, Caijuan Li, Yizhi Chen, Jiale Gao, Jiawei Li, Chunhui Huang, Zhaoming Liu, Wei Wang, Xiao Zheng, Xichen Song, Jianhao Wu, Jiaxi Wu, Oscar Junhong Luo, Zhuchi Tu, Shihua Li, Xiao-Jiang Li, Liangxue Lai, Sen Yan

“…The impact on motor abilities was assessed via behavioral experiments, providing a comprehensive evaluation of the treatment's effectiveness. …”
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Inhibitory Effect of PRMT5/MTA Inhibitor on MTAP‐Deficient Glioma May Be Influenced by Surrounding Normal Cells by Yunjie Wang, Xiaohui Sun, Runchen Ma, Xiaofan Zhang, Shengmin Ji, Zhaofeng Liu, Gangqiang Yang, Hongbo Wang, Peng Zhang, Jianzhao Zhang, Jingwei Tian

“…Conclusions Due to the complexity of the tumor environment in vivo, the anti‐tumor effects of PRMT5/MTA‐specific inhibitors may be somewhat attenuated, and their ability to achieve suitable therapeutic effects in the clinic might require more in‐depth studies.…”
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MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…Herein, we revealed for the first time that the migration, invasion, and metastatic abilities of glioma cells decreased significantly after MYH9 expression was downregulated. …”
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The Characteristics Variation of Hepatic Progenitors after TGF-β1-Induced Transition and EGF-Induced Reversion by Ping Wang, Min Cong, Tianhui Liu, Aiting Yang, Guangyong Sun, Dong Zhang, Jian Huang, Shujie Sun, Jia Mao, Hong Ma, Jidong Jia, Hong You

“…During TGF-β1-induced transition and EGF-induced reversion, hepatic oval cells sustained their progenitor cell marker expression, including α-fetoprotein, albumin, and cytokeratin-19. The proliferation ability and differentiation potential of these cells were suppressed by TGF-β1, while EGF resumed these capacities to the level similar to the control cells. …”
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Target-specific peptides for BK virus agnoprotein identified through phage display screening: advancing antiviral therapeutics by Xiaofei Xing, Jingxian Han, Keke Wang, Fuyun Tian, CuiXia Jiang, Wei Liang, Lin Qi, Xin Yue, Yinhang Wen, Yuwei Hu, Hui Qiao

Subjects: “…BK virus…”
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Clinically Relevant Solution for the Hypothermic Storage and Transportation of Human Multipotent Mesenchymal Stromal Cells by Yuriy Petrenko, Milada Chudickova, Irena Vackova, Tomas Groh, Eliska Kosnarova, Jitka Cejkova, Karolina Turnovcova, Alexander Petrenko, Eva Sykova, Sarka Kubinova

“…The hypothermic storage of MSCs in the new buffered trehalose solution provided significantly higher MSC recovery rates and ability of cells for attachment and further proliferation, compared to Plasma-Lyte® 148 and Ringer’s solution, and was comparable to research-grade HypoThermosol® FRS. …”
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The potential of Curcuma longa L. bioactive compounds as RSK inhibitors for the treatment of prostate cancer: in silico study by Olusola Olalekan Elekofehinti, Foluso Adeola Taiwo, Moses Orimoloye Akinjiyan, Ifeoluwa Rachael Adetoyi, Folasade Oluwatobiloba Ayodeji, Adedotun Olayemi Oluwatuyi, Oluwapelumi Nifesimi Akintoye, Idayat Oyinkansola Kehinde, Bolanle Esther Adedapo, Opeyemi Iwaloye

“…Methods Molecular docking and other computational analysis procedures using the Schrodinger suite were used to predict in silico the ability of bioactive compounds from turmeric (Curcuma longa) to bind effectively to RSK as potent inhibitors. …”
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Process variables in mixture experimental design applied to wood plastic composites by Javier Cruz-Salgado, Sergio Alonso-Romero, Edgar Augusto Ruelas-Santoyo, José Alfredo Jiménez-García, Israel Miguel-Andrés, Roxana Zaricell Bautista-López

“…The PRESS value of 3.38 confirms the model’s ability to accurately predict new data. The absence of high multicollinearity, as indicated by variance inflation factor (VIF) values below 5, further supports the model's stability and interpretability. …”
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Preparation and transfer of Burkholderia mallei production strain 5584 in accordance with the biosafety requirements by E. A. Artemeva, L. A. Melnikova, A. P. Rodionov

“…The following steps were taken due to the official request from FKP Kursk Biofactory – BIOK Company for the transfer of Burkholderia mallei production strain 5584 from the collection of the institution: the strain was passaged in golden hamsters, its viability was determined and biological properties of the culture were studied. …”
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Co-inoculation of Trichoderma viride with Azospirillum brasilense could suppress the development of Harpophora maydis-infected maize in Egypt by Rasha M. Elmeihy, Omar A. Hewedy, Maryam S. Alhumaidi, Khadijah A. Altammar, Eman O. Hassan, Samah A. El-Debaiky

“…A. brasilense and T. viride filtrates were also shown to suppress H. maydis growth, in addition to their ability to produce gibberellic and indole acetic acids. …”
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Transitive reasoning in the adult domestic hen in a six-term series task by R. Degrande, O. Amichaud, B. Piégu, F. Cornilleau, P. Jardat, V. H.B. Ferreira, V. Colson, L. Lansade, L. Calandreau

“…Few bird species have been tested for TI to date, which limits our knowledge of the phylogenetic spread of such reasoning ability. Here we tested TI in adult laying hens using a more solid methodology, the 6-term series task, which has not been tested in poultry so far. …”
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Mitochondria-Targeting and Oxygen Self-Supplying Eccentric Hollow Nanoplatform for Enhanced Breast Cancer Photodynamic Therapy by Jing Li, Yu Wang, Jun Tao, Xiaodan Su, Feipeng Zhu, Wei Lu, Xiaolin Han, Meng Dang, Lixing Weng

“…The EHMONs-Ce6-CTPP@PFCs with oxygen-carrying ability can alleviate hypoxia after entering in the cancer cell. …”
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Evaluation of Digital PCR as a Technique for Monitoring Acute Rejection in Kidney Transplantation by Hyeseon Lee, Young-Mi Park, Yu-Mee We, Duck Jong Han, Jung-Woo Seo, Haena Moon, Yu-Ho Lee, Yang-Gyun Kim, Ju-Young Moon, Sang-Ho Lee, Jong-Keuk Lee

“…We compared the detection abilities of the QX200, RainDrop, and QuantStudio 3D dPCR systems. …”
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Studies on wear resistance of the radial bearing design taking into account rheological properties of micropolar lubricant by M. A. Mukutadze, H. N. Abdulrahman, V. E. Shvedova, G. A. Badakhov, N. V. Zinoviev

“…The novelty of the work lies in the concretization of the technique of engineering calculations for the design of an effective radial bearing with an antifriction polymer coating with an axial groove on the bearing surface of the bearing bush, taking into account the dependence of the rheological properties of a micropolar lubricant on pressure and temperature in a turbulent mode, which makes it possible to estimate the value of the main operational characteristics: hydrodynamic pressure, load ability and coefficient of friction, as well as to expand the scope of practical application of models for engineering calculations. …”
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Unified Visual-Aware Representations for Data Analytics by Ladislav Peska, Ivana Sixtova, David Hoksza, David Bernhauer, Jakub Lokoc, Tomas Skopal

“…One of the characteristics of big data is its internal complexity and variety manifested in many types of datasets that are to be managed, searched, or analyzed. …”
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