Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex by Xiaotong Diao, Qinghong Shang, Mengqi Guo, Yubin Huang, Meina Zhang, Xiaoyu Chen, Yinping Liang, Xiangnan Sun, Fan Zhou, Jingjing Zhuang, Shuang-Jiang Liu, Christoph F. A. Vogel, Fraydoon Rastinejad, Dalei Wu

“…AHR’s PAS-B domain utilizes eight conserved residues whose dynamic rearrangements account for the ability to bind to ligands through hydrophobic and π-π interactions. …”
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The solvent effect, preferential solvation of metformin hydrochloride in binary mixed solvents of methanol/ethanol + water mixtures from 278.15 K to 323.15 K by Adel Noubigh, Abdalazeem A. Omar, Manef Abderrabba

“…The KAT-LSER model revealed that solvent polarity (π*) and ability to accept hydrogen bonds (α) were key factors in MET-HCl dissolution in methyl alcohol and water, as well as ethyl alcohol and water.…”
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Integrative analysis of single-cell and transcriptome sequencing with experimental validation reveals PKHD1L1 as a novel biomarker in lung adenocarcinoma by Xiangqian Zhang, Jie Wang, Hanyang Su, Xiaojin Liu

“…In vitro experiments revealed that the over-expression of PKHD1L1 significantly inhibited the proliferation and migration ability of LUAD cell lines. These findings suggest that PKHD1L1 is an important prognostic indicator and a potential therapeutic target for LUAD.…”
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Relationship between parent-adolescent discrepancies in educational expectations and academic burnout: A response surface analysis by Xuanye Bai, Youzhi Song, Minlian Liang, Jia Peng, Tingting Ruan, Heping Xie

“…The primary focus was on the mediating effect of students' academic self-efficacy, which reflects an individual's confidence in their ability to manage academic tasks. To precisely address the matching and discrepancy in parent-adolescent educational expectations, as well as to quantify the mediating role of academic self-efficacy, polynomial regression and response surface analysis techniques were employed. …”
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A Multicenter Observational Prospective Cohort Study of Association of the Prehospital National Early Warning Score 2 and Hospital Triage with Early Mortality by Francisco Martín-Rodríguez, Raúl López-Izquierdo, Carlos del Pozo Vegas, Juan F. Delgado-Benito, Carmen del Pozo Pérez, Virginia Carbajosa Rodríguez, Agustín Mayo Iscar, José Luis Martín-Conty, Carlos Escudero Cuadrillero, Miguel A. Castro-Villamor

“…Aim of the Study. To evaluate the ability of the prehospital National Early Warning Score 2 scale (NEWS2) to predict early mortality (within 48 hours) after the index event based on the triage priority assigned for any cause in the emergency department. …”
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Experimental Verification of the Field Robotic System for Pipeline Maintenance by Thanh Phuong Nguyen, Hung Nguyen, Nhat Minh Ngo, Ha Quang Thinh Ngo

“…For the laboratory validation, the hardware robot is confirmed the working abilities as well as some trial results. Lastly, this robot must be exemplified in the real scene such as factory or site construction. …”
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Accurate prediction for electro-oxidation regeneration of chromium- containing waste acid based on artificial neural network by SHI Yaqi, MENG Guangyuan, CHEN Peng, ZHANG Xinwan, FU Tao, YANG Zhengwu, ZHANG Liansheng, ZHANG Lehua

“…Finally, the average relative error between predicted value and experimental value was 0.14%, which indicated that the model had good generalization ability. The artificial neural network model overcame the difficulty of predicting electrochemical processes due to multi-parameter, nonlinearity and time variability, and could realize the prediction of Cr(Ⅵ) regeneration under complex mapping conditions, which was of great significance for the optimization and control of electrochemical processes.…”
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Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma by Shibing Zhao, Dasheng Tian, Fei Huang, Lei Wang, Jinhao Cheng, Zhitao He, Qitian Shen, Shuai Liang, Deliang Gong, Jun Liu, Chengfeng Yi, Chun Zhang, Erbao Bian, Juehua Jing, Tao Wang

“…Analysis of internal and external datasets revealed that the ERG signature has good predictive ability and reproducibility. Immune analysis demonstrated a significant correlation between OS patient immune status and ERG signature score. …”
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Gamma-ray attenuation characteristics of polypropylene filled with nano-sized and bulk Bi2O3 and CuO by Gouda Mona M., Shebly Mona, Habanjar Khulud, Obeid Amro, Awad Ramadan, Badawi Mohamed S.

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Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cel... by Graciela Ruiz, Heriberto A. Valencia-González, Delia Pérez-Montiel, Felipe Muñoz, Rodolfo Ocadiz-Delgado, Jorge Fernández-Retana, Carlos Pérez-Plasencia, Osbaldo Reséndis-Antonio, Patricio Gariglio, Alejandro García-Carrancá

“…Importantly, we observed that lentiviral-mediated transduction of these factors confers, to a nontumorigenic immortalized human cell line, properties of cancer stem cells as the ability to form tumors in a mouse model. When we performed a meta-analysis using microarray data from cervical cancer biopsies and normal tissues, we found that the expression of OSKM-N and some target genes allowed separating tumor and normal tissues between samples, which enhanced the importance of OSKM-N in the tumorigenesis. …”
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Antimicrobial Effectiveness of Clove Oil in Decontamination of Ready-to-Eat Spinach (<i>Spinacia oleracea</i> L.) by Abigail A. Armah, Kelvin F. Ofori, Kenisha Sutherland, Emmanuel Otchere, Winter A. Lewis, Wilbert Long

“…A washing experiment was used to evaluate CO’s ability to inhibit bacterial growth on inoculated RTE spinach and in the wash water. …”
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The Utility of Perirenal Fat in Determining the Risk of Onset and Progression of Diabetic Kidney Disease by Hongtu Hu, Wei Liang, Zongwei Zhang, Zikang Liu, Fan Chu, Yan Bao, Jialu Ran, Guohua Ding

“…Perirenal fat (PRF) has multiple effects on the kidney through its physical structure and adipocytokine-secreting ability. The present study explored the relationship between PRF thickness and the onset and progression of albuminuria in patients with diabetes. …”
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The Impact of Care Upon Alzheimer Patient’s Family Caregiver in Sulaimani City by Farida Abdulqadir Tahir

“…Family Care giving for relatives with Alzheimer, often includes assisting them with one or more activities of daily living, as Alzheimer is one of the progressive impairment diseases in patient’s physical and cognitive ability. The aim of this study is to assess the effect of being a family caregiver of Alzheimer patients in Sulaimani city. …”
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Fuzzy Terminal Sliding Mode Control with Compound Reaching Law and Time Delay Estimation for HDU of Legged Robot by Kaixian Ba, Bin Yu, Yaliang Liu, Zhengguo Jin, Zhengjie Gao, Junxiao Zhang, Xiangdong Kong

“…The experimental results show that the proposed controller greatly improves the system position control performance and has a strong disturbance rejection ability and a good adaptability under different working conditions. …”
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Gamification Application for Promoting and Encouraging Physical Activity in the Elderly by Narmin Mohammed Noori, Awaz Naaman Saleem, Muhammed Anwar

“…Isolation, shifts in cognition, and a decline in motor abilities are some of the negative consequences of ageing that make many seniors wary of exercise programs. …”
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Injectable Tumoricidal Neural Stem Cell-Laden Hydrogel for Treatment of Glioblastoma Multiforme—An In Vivo Safety, Persistence, and Efficacy Study by Jasmine L. King, Alain Valdivia, Shawn D. Hingtgen, S. Rahima Benhabbour

“…Conclusions: Collectively, we demonstrated the ability to encapsulate, retain, and deliver iNSCs in an injectable CS hydrogel that is well tolerated with better survival rates than iNSCs alone.…”
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Comparative analysis of seasonal wind power using Weibull, Rayleigh and Champernowne distributions by Bienvenu Sumaili Ndeba, Omaima El Alani, Abdellatif Ghennioui, Mostafa Benzaazoua

“…Wind speed data at 10 m hub height over three years (2021–2023) from Ben Guerir, Morocco, were analyzed using statistical metrics such as Root Mean Square Error (RMSE), Mean Absolute Error (MAE), Mean Bias Error (MBE), Coefficient of Determination (R2), Akaike Information Criterion (AIC), and Bayesian Information Criterion (BIC). The Champernowne distribution outperformed the other models across all metrics, achieving the lowest RMSE (0.00036), MAE (0.00022), AIC (650.52), and BIC (689.46), and the highest R2 (0.99998). …”
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Climate Projections and Pacific Lamprey Conservation: Evidence That Larvae in Natural Conditions May Be Resilient to Climate Warming by Timothy A. Whitesel, Paul M. Sankovich

“…Whether larval Pacific lampreys in natural conditions can tolerate these temperatures is unknown. To evaluate this ability, we conducted Direct Acute Exposure (DAE) experiments using simulated natural daily temperature (SNT) cycles in the laboratory and occupancy surveys in the Umatilla River (river). …”
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விவேக சிந்தாமணி கூறும் மானுட விழுமியங்கள் / Human Values in Viveka Cintamani by முனைவர் சு. சுசா / Dr. S. Susa

“…In the hierarchy of living beings, humans distinguish themselves as the foremost species, endowed with the ability to reason. Literary records indicate that humans have integrated themselves with the environment, considering not only their own well-being but also that of the entire ecosystem. …”
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Psychological impacts of "screen time" and "green time" for children and adolescents: A systematic scoping review. by Tassia K Oswald, Alice R Rumbold, Sophie G E Kedzior, Vivienne M Moore

“…The ways screen time and green time were conceptualised and measured were highly heterogeneous, limiting the ability to synthesise the literature. The preponderance of cross-sectional studies with broadly similar findings, despite heterogeneous exposure measures, suggested results were not artefacts. …”
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