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  1. 3681

    Factors that influence the adoption of a school-based eHealth alcohol prevention program among Spanish personnel: a mixed methods study by Ester Alejandra Rosado-Pulido, Pablo Fernández-León, Marta Lima-Serrano, Hein de Vries

    Published 2025-02-01
    “…Intenders perceived a higher personal relevance and responsibility towards using the program, more self-efficacy (e.g., ability to understand, manage time and incorporate the program) and positive social influences from their colleagues, as well as greater willingness in preparing action plans, such as monitor students’ alcohol consumption and discussing the program with coworkers, than the non-intenders group. …”
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  2. 3682

    FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss by Lijun Li, Renjin Lin, Yang Xu, Lingdi Li, Zhijun Pan, Jian Huang

    Published 2025-02-01
    “…Furthermore, our approach can distinguish genes that exhibit osteogenic differentiation characteristics. This ability can aid in the identification of novel genes associated with osteogenic differentiation, which can be utilized in the treatment of osteoporosis. …”
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  3. 3683

    Lateral Decubitus 360° Capsular Release for Treatment of Recalcitrant End-Stage Adhesive Capsulitis by Juan Bernardo Villarreal-Espinosa MD, Rodrigo Saad Berreta BA, Richard Danilkowicz MD, Udit Dave BS, Melissa Carpenter BS, Jorge Chahla MD, PhD, Nikhil N. Verma MD

    Published 2025-01-01
    “…While traditionally performed in the beach-chair position, capsular release performed via a lateral decubitus approach may provide enhanced visualization and the ability to perform a 360° release without iatrogenic injury to the cartilage surfaces. …”
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  4. 3684

    Translation, content validity and internal structure of the Brazilian version of the Adolescent Resilience Questionnaire (B-ARQ). by Genara Brum Gomes, Luisa Gatti-Reis, Matheus França Perazzo, Marisa Alves Araújo, Flávio Freitas Mattos, Deirdre Gartland, Saul Martins Paiva, Isabela Almeida Pordeus

    Published 2025-01-01
    “…Resilience refers to one's ability to face life's challenges and achieve positive outcomes, and has drawn increasing interest from researchers and policymakers. …”
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  5. 3685

    Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab by Hans-Christoph Diener, Kathleen A. Day, Sarah Lipsius, Sheena K. Aurora, Nada A. Hindiyeh, Holland C. Detke

    Published 2025-02-01
    “…Galcanezumab is a monoclonal antibody to calcitonin gene-related peptide which is approved for the preventive treatment of migraine. Ability to convert patients from chronic migraine frequency to episodic migraine (EM) frequency is a clinically relevant and desirable outcome when prescribing preventive treatments to patients with CM. …”
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  6. 3686

    Short communication: The importance of random effects in detecting purging of inbreeding depression: A model comparison in Pannon White rabbits by I. Nagy, I. Curik, A.T. Nguyen, J. Farkas, Gy. Kövér

    Published 2025-02-01
    “…We assessed the classification abilities (predictive power) of these models using Receiver Operating Characteristic (ROC) and Precision-Recall (PR) curves, where larger areas under the curve (AUC) indicate better classification performance. …”
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  7. 3687

    Smart Pharmaceutical Monitoring System With Personalized Medication Schedules and Self-Management Programs for Patients With Diabetes: Development and Evaluation Study by Jian Xiao, Mengyao Li, Ruwen Cai, Hangxing Huang, Huimin Yu, Ling Huang, Jingyang Li, Ting Yu, Jiani Zhang, Shuqiao Cheng

    Published 2025-02-01
    “…Individualized medication schedules and self-management programs were generated based on patient-specific conditions and needs, using an app framework to build patient-side contact pathways. The system’s ability to provide medication guidance and health management was assessed by senior health care professionals using a 5-point Likert scale across 3 groups: outputs generated by the system (DUMS group), outputs refined by pharmacists (intervention group), and outputs generated by ChatGPT-4 (GPT-4 group). …”
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  8. 3688

    Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing by Sasa Vasilijic, Richard Seist, Zhenzhen Yin, Lei Xu, Konstantina M. Stankovic

    Published 2025-02-01
    “…Methods To identify effector molecules involved in VS-induced SNHL, we analyzed 47 immune-related factors secreted by tumor tissue in over 50 patients with sporadic VS and studied their correlation with preoperative hearing ability and tumor size. The most promising effector molecules were validated in vivo in an anatomically accurate mouse model of VS, and in vitro with mouse fibroblasts (L929) and auditory cell lines representing pro-sensory precursors of hair cells (UB-OC1) and auditory neuroblasts (US-VOT-N33). …”
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  9. 3689

    Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis by Shasha Huang, Shumin He, Fei Xiao, Yang Zhou, Su Lyu

    Published 2025-02-01
    “…ROC curve analysis showed that the level of circ_PPARG in peripheral blood had a good ability to distinguish patients with FM from healthy controls. …”
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  10. 3690

    Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

    Published 2025-02-01
    “…Results Using machine learning algorithms, five biomarkers (TSPO, HIGD1A, NDUFAB1, NT5DC3, and MRPS30) were successfully identified, and a nomogram model with strong diagnostic ability and accuracy (AUC > 0.9) was constructed. …”
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  11. 3691

    Bibliotherapy Services in Public Libraries: the Case of Lithuania by Jurgita Girčienė, Miglė Damijonaitytė

    Published 2023-12-01
    “…Although librarians both independently and institutionally, usually through projects or occasional trainings deepen their knowledge in this field, yet its lack is still mentioned, and in particular, the lack of practical skills necessary for organizing more formal active bibliotherapy activities, which leads to a lack of confidence in their own abilities and induces them to limit themselves to the role of an event organizer with a guest lecturer. …”
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  12. 3692
  13. 3693

    HUBUNGAN ANTARA KEMAMPUAN BERPIKIR KRITIS DENGAN HASIL BELAJAR MELALUI MODEL INKUIRI TERBIMBING by Wahyu Youllanda, Rosane Medriati, Eko Swistoro

    Published 2020-12-01
    “…The results of the study, data analysis and hypothesis testing showed that there is a positive correlation between the ability to think critically with student learning outcomes through the guided inquiry model in class X MIPA SMA N 4 Bengkulu City that is 0.607 which is in the high category and the magnitude of the relationship obtained is 36.89 %.   …”
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  14. 3694

    Alternatives to Traditional Physical Science Laboratory Experiences: A Review by Mercy Ogunsola-bandele, Dietmar Kennepohl

    Published 2024-12-01
    “…This is evidenced by conflicting research reports on students’ ability to manipulate laboratory equipment after participating in online experimentation. …”
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  15. 3695

    Yoruba Epistemology, Art, Language and the Universe of Meanings: A Meta-Analysis by Michael O. Afolayan

    Published 2021-12-01
    “…Although short in quantity, I consider it to be loaded in quality, contents, intents, intensities, and in its ability to problematize a discourse critical to our understanding of indigenous scholarship and all its epistemological implications that span the entire landscape of the humanities. …”
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  16. 3696

    LncRNA GAS5 inhibits glioma progression through miR-135b-5p/APC axis by ZHANG Jidong, WANG Yutao, JI Jianwen

    Published 2025-02-01
    “…The results of CCK-8, Transwell and wound healing assays revealed that overexpression of GAS5 significantly inhibited the viability, invasion and migration abilities in T98 cells when compared with the cells of the vector group (P<0.01). …”
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  17. 3697

    Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

    Published 2025-02-01
    “…In-vitro spheroid assay was performed to explored the PJLME-AF cytotoxic effects on tumour spheroid forming ability of melanoma cells. Additionally, the anti-tumor efficacy of PJLME-AF was tested in an in-vivo C57BL/6 mouse model. …”
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  18. 3698

    External validation and revision of the Lafontaine criteria for unstable distal radius fractures: a retrospective study by Pornpanit Dissaneewate, Phatklao Thanavirun, Yanin Tangjaroenpaisan, Kantapon Dissaneewate

    Published 2025-02-01
    “…Therefore, we aimed to evaluate the Lafontaine criteria as a diagnostic prediction rule for distal radius fractures, assess the inter-rater reliability and predictive ability of various parameters for distal radius instability, and develop new criteria for fracture instability using reliable and highly predictive factors. …”
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  19. 3699

    Comparison of phenotypic and genetic traits of ESBL-producing UPEC strains causing recurrent or single episode UTI in postmenopausal women by Michelle Kalu, Peter Jorth, Annie Wong-Beringer

    Published 2025-02-01
    “…Conclusion Our findings indicate strain-specific ability to persist inside BECs with the recurrent strains exhibiting increased ompT expression inside BECs and higher intracellular bacterial burden compared to strains causing single episode UTI. …”
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  20. 3700

    PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

    Published 2025-02-01
    “…In 786-O cells with low PTEN expression, further induction of PTEN overexpression significantly inhibited PI3K/AKT signaling activity (p < 0.01), accompanied by decreased cell viability and migration ability. These results indicate that the expression pattern of PTEN in RCC is complex, but its overexpression can exert tumor-suppressive effects by inhibiting the PI3K/AKT signaling pathway. …”
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