Integrative analysis of immunogenic PANoptosis and experimental validation of cinobufagin-induced activation to enhance glioma immunotherapy by Yonghua Cai, Heng Xiao, Shuaishuai Xue, Peng Li, Zhengming Zhan, Jie Lin, Zibin Song, Jun Liu, Wei Xu, Qixiong Zhou, Songtao Qi, Xi’an Zhang, Ziyi Luo

“…Cinobufagin, identified as a PANoptosis activator, was evaluated for its ability to induce PANoptosis and enhance anti-tumor immune responses both in vitro and in vivo GBM models. …”
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Activity of sorghum aphid and its natural enemies in the context of agroecological and weather conditions by Tomasz E. Koralewski, Tomasz E. Koralewski, Michael J. Brewer, Leonel L. Deleon, Norman C. Elliott, Kristopher Giles, Adrianna Szczepaniec, Ashleigh M. Faris, Ashleigh M. Faris

“…Agroecological-oriented areawide pest management leverages the innate ability of agroecosystem to suppress pests, and thus to utilize ecosystem services, a key component of sustainable agriculture. …”
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Comprehensive study for radiation shielding features for Bi2O3–B2O3–ZnO composite using computational radioanalytical Phy-X/PSD, MCNP5, and SRIM software by Y. S. Alajerami, M. H. A. Mhareb, M. I. Sayyed, M. Kh. Hamad, F. Kodeh, M. Rashad, M. Mitwalli

“…The study's findings are valuable insights from thoroughly examining these parameters, which can potentially improve the radiation protection abilities of Bi2O3–B2O3–ZnO glasses. This study represents a significant step in developing more efficient and safer materials for gamma radiation shielding applications.…”
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Multiphoton imaging-based quantifiable collagen signatures for predicting outcomes in patients with pancreatic ductal adenocarcinoma by Xiwen Chen, Jikui Miao, Xingxin Huang, Xiahui Han, Liqin Zheng, Jianxin Chen, Linying Chen, Lianhuang Li

“…Our statistical results demonstrate that as two new optical biomarkers, TACS- and M-TACS-score, are independent prognostic factors and have good discriminatory ability (high AUC) as well as risk stratification (high HR) comparing with traditional clinical model (combining seven clinical risk factors, age, sex, TNM stage, tumor location and differentiation, perineural and lymph-vascular invasion) in predicting overall survival (OS) of patients with PDAC, highlighting their potential prognostic and predictive value. …”
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Multi-trace elements-enriched functional drink accelerates gastric ulcer repair via the HGF/c-Met/STAT3 pathway by Yongnan Piao, Nuoya Wang, Mingji Jin, Jianyu Piao, Mingfeng Han, Zifei Wang, Chunhua Quan, Jishan Yin, Zhonggao Gao, Wenxiang Cui, Shuangqing Wang, Xiuquan Quan

“…Finally, FD reduced the severity of gastric mucosal injury caused by invasive factors, improved the morphological structure of gastric mucosal cells, enhanced the ability of oxidative stress, and inhibited excessive inflammatory response. …”
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Exoscope-assisted spine surgery: Current applications and future directions–A short review by Tomas Ferreira, Sakshi Roy, Joecelyn Kirani Tan, Wireko Andrew Awuah, Vallabh Shet, Favour Tope Adebusoye, Adrenito Nicolas, Toufik Abdul-Rahman

“…Recently, exoscope-assisted spine surgery has emerged as a promising technological advancement that may revolutionise the field due to its ability to facilitate precise and advanced visualisation techniques that ensure successful outcomes in spine surgeries. …”
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The effectiveness of dance interventions on the cognitive functioning of people with dementia or cognitive impairment: A systematic review by Dauda Salihu, Surajo Kamilu Sulaiman, Umar Muhammad Bello, Osama Mohamed Elsayed Ramadan, Hadiza Yahaya, Muhammad Chutiyami

“… Background & Aim: Dementia significantly impair cognitive abilities, well-being, and the functioning of daily life, but there is no cure yet. …”
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Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells by Peng Wang, Haiyue Zhao, Wei Chen, Yuhui Guo, Shuo Zhang, Xin Xing, Shuai Yang, Fengkun Wang, Juan Wang, Zengwu Shao, Yingze Zhang

“…CTP/miR OE -EVs exhibit excellent ability to specifically target cartilage and ameliorate OA pathology. …”
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A novel adaptive droop-based SoC balancing control strategy for distributed energy storage system in DC microgrid by Liangliang Guo, Xinrui Liu, Xinyu Li, Rui Wang, Hanwen Ren, Zhiliang Wang, Qiuye Sun

“…The results show that, compared with the existing methods, the proposed control strategy can achieve SoC balance faster, has higher current allocation accuracy, and has better ability to maintain bus voltage stability.…”
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Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models by Ling Xiong, Dustin Beyer, Na Liu, Tina Lehmann, Sophie Neugebauer, Sascha Schaeuble, Oliver Sommerfeld, Philipp Ernst, Carl-Magnus Svensson, Sandor Nietzsche, Sebastian Scholl, Tony Bruns, Nikolaus Gaßler, Markus H. Gräler, Marc Thilo Figge, Gianni Panagiotou, Michael Bauer, Adrian T. Press

“…Using a preclinical murine sepsis model, we found that both PKCα knockout and the use of a PKCα-inhibitor midostaurin successfully restored liver function without hindering the host’s response or ability to clear the pathogen, highlighting PKCα’s vital role in excretory liver failure. …”
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Gut microbial subtypes and clinicopathological value for colorectal cancer by Shuwen Han, Jing Zhuang, Yifei Song, Xinyue Wu, Xiaojian Yu, Ye Tao, Jian Chu, Zhanbo Qu, Yinhang Wu, Shugao Han, Xi Yang

“…Finally, the predictive ability of CatBoost models for CRC identification was improved based on gut microbial subtypes. …”
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mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms by Barnabé, Christian, Sempéré, Guilhem, Manzanilla, Vincent, Millan, Joel Moo, Amblard-Rambert, Antoine, Waleckx, Etienne

“…This software is a versatile open-source tool for processing amplicon sequences, offering advantages such as high speed, efficient memory usage, and the ability to handle large datasets. It provides functions for various tasks such as dereplication, clustering, chimera detection, and taxonomic assignment. …”
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Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps by Colinet, Dominique, Cavigliasso, Fanny, Leobold, Matthieu, Pichon, Apolline, Urbach, Serge, Cazes, Dominique, Poullet, Marine, Belghazi, Maya, Volkoff, Anne-Nathalie, Drezen, Jean-Michel, Gatti, Jean-Luc, Poirié, Marylène

“…We also show that both RhoGAP families have undergone evolution under positive selection and that almost all of these RhoGAPs lost their GAP activity and GTPase binding ability due to substitutions in key amino acids. These results suggest an accelerated evolution and functional diversification of these vesicle-associated RhoGAPs in the two phylogenetically distant parasitoid species. …”
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Deposition behaviors and interfacial interaction mechanism between carboxyl-modified polystyrene nanoplastics and magnetite in aquatic environment by Meimei Ran, Xin Nie, Jingxin Wang, Ruiyin Xie, Xiaoping Lin, Hanjun Zhu, Quan Wan, Yuhong Fu

“…Organic macromolecules (OMs) markedly inhibited the interfacial interaction and deposition of COOH-PSNPs with magnetite by enhancing the electrostatic repulsion and steric hindrance between COOH-PSNPs and magnetite due to the formation of magnetite-OM associations. The inhibition abilities followed the order sodium alginate (0.1 mM) > humic acid (0.2 mM) > bovine serum albumin (5 mM). …”
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Culture-independent detection of Mycobacterium tuberculosis complex DNA using targeted next generation sequencing in African buffalo (Syncerus caffer) oronasal swabs in South Afric... by Sinegugu Kholeka Mhlophe, Charlene Clarke, Giovanni Ghielmetti, Giovanni Ghielmetti, Megan Matthews, Tanya Jane Kerr, Michele Ann Miller, Wynand Johan Goosen, Wynand Johan Goosen

“…However, these methods are not without their shortfalls, with a suboptimal ability to discern true positive results amidst certain non-tuberculous mycobacteria (NTM) interference. …”
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Isolation, genetic, and biological characterization of human adenovirus type 55 positive isolates from Wuhan, China by Jing Xie, Yan Wang, Huan Li, Bingxiu Tan, Zhengying Yu, Lizhong Li, Wei Zhang, Hongbin Song, Leili Jia

“…Results HAdV-55-174 exhibited the highest replication ability in cultured cells compared to other strains, so this strain was selected for further investigation. …”
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Post-treatment of rat aflatoxicosis by camel milk and silymarin by Nahla H. Hassaneen, Shabaan A. Hemeda, Abeer F. El Nahas, Ghadeer M. Albadrani, Muath Q. Al-Ghadi, Zuhair M. Mohammedsaleh, Sabreen E. Fadl, Eman M. El-Diasty, Hader I. Sakr, Hader I. Sakr

“…Moreover, the histopathology of the liver and testes was done along with expression levels of specific genes in the liver and testes.ResultsThe outcomes showed that the post-treatment with silymarin and camel milk improved biochemical markers in serum and ability to reproduce.ConclusionIn conclusion, post-treatment with camel milk and silymarin could mitigate the negative effect of AFB1 on rats.…”
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The molecular receptor NKBB enhances the persistence and anti-hepatocellular carcinoma activity of GPC3 CAR-T cells by Minghao Sui, Tiantian Liu, Xuanli Song, Ji Li, Han Ding, Yuqian Liu, Xinyu Wang, Huimin Liu, Yuchan Xue, Jianni Qi, Miao Zhang, Songbo Zhao, Qiang Zhu

“…Our study showed that the molecular receptor NKBB conferred GPC3 CAR-T cells with enhanced migration and infiltration abilities towards HCC, higher central memory T (TCM) cell proportion and proliferation capacity, and reduced exhaustion level. …”
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Habitat fragmentation increases the risk of local extinction of small reptiles: A case study on Phrynocephalus przewalskii by Cui Yang, Yue Qi, Jiayuan Guo, Liangfei Peng, Neng Xiong, Wenya Zhang, Wei Zhao

“…Reptiles, particularly smaller species with limited migratory abilities, are especially vulnerable to these changes. …”
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Enhanced brightness and photostability of dye-sensitized Nd-doped rare earth nanocomposite for in vivo NIR-IIb vascular and orthotopic tumor imaging by Syue-Liang Lin, Shih-Po Su, Yuan-Zhen Yang, Cheng-Yu Chiang, Hsin-Yu Chi, Cheng Allen Chang, Tse-Ying Liu, Huihua Kenny Chiang

“…The dye-sensitized onion-like Nd-RENP nanocomposite presents a significant advancement in NIR-IIb imaging, providing enhanced brightness and photostability. Its ability to maintain clear and stable imaging over extended periods suggests potential applications in dynamic vascular and tumor-targeted imaging. …”
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