When People Parent Together: Let’s Talk About Coparenting by James McHale, Jason Baker, Heidi Liss Radunovich

“…FCS2277, a 7-page fact sheet by James McHale, Jason Baker, and Heidi Liss Radunovich, will help anyone who is "coparenting" children--raising children with the help of another adult. …”
Get full text

Influence of Effective Nucleon Mass on Equation of State for Supernova Simulations and Neutron Stars by Shuying Li, Junbo Pang, Hong Shen, Jinniu Hu, Kohsuke Sumiyoshi

“…The properties of cold neutron stars, calculated using the TM1m model, are compatible with the existence of a 2 M _⊙ pulsar and the latest constraints on the tidal deformability and radii of a canonical 1.4 M _⊙ neutron star, derived from astrophysical observations.…”
Get full text

A novel uORF regulates folliculin to promote cell growth and lysosomal biogenesis during cardiac stress by Maja Bencun, Laura Spreyer, Etienne Boileau, Jessica Eschenbach, Norbert Frey, Christoph Dieterich, Mirko Völkers

“…The tumor suppressor folliculin (FLCN) is part of the network regulating non-canonical mTORC1 activity. FLCN activates mTORC1 by functioning as a guanosine triphosphatase activating protein (GAP). …”
Get full text

Fast Random Permutation Tests Enable Objective Evaluation of Methods for Single-Subject fMRI Analysis by Anders Eklund, Mats Andersson, Hans Knutsson

“…To exemplify the permutation-based approach, brain activity maps generated by the general linear model (GLM) and canonical correlation analysis (CCA) are compared at the same significance level.…”
Get full text

Alternative splicing of EZH2 regulated by SNRPB mediates hepatocellular carcinoma progression via BMP2 signaling pathway by Xingyu Wang, Weiyi Liu, Chunai Zhan, Yuanyuan Zhang, Xinyu Li, Yaoyun Wang, Mengfei Sheng, Madiha Maqsood, Hang Shen, Anmin Liang, Wei Shao

“…Here, we analyzed both our own and published transcriptomic data, obtaining 19 splice variants of EZH2 in addition to canonical full-length EZH2-A in HCC. We found that expression of EZH2-A/EZH2-B in tumor tissues and cell lines was significantly higher than in normal tissues. …”
Get full text

Complements and coregularity of Fano varieties by Fernando Figueroa, Stefano Filipazzi, Joaquín Moraga, Junyao Peng

“…In the case of Fano varieties of absolute coregularity $1$ , we show that they admit an N-complement with N at most 6. …”
Get full text

Coordinated neuron-specific splicing events restrict nucleosome engagement of the LSD1 histone demethylase complex by Robert S. Porter, Sojin An, Maria C. Gavilan, Masayoshi Nagai, Yumie Murata-Nakamura, Bo Zhou, Katherine M. Bonefas, Olivier Dionne, Jeru Manoj Manuel, Joannie St-Germain, Suzanne Gascon, Jacqueline Kim, Liam Browning, Benoit Laurent, Uhn-Soo Cho, Shigeki Iwase

“…Furthermore, in vitro reconstitution of the canonical and neuronal PHF21A-LSD1 complexes, combined with in vivo methylation mapping, identified the neuronal complex as a hypomorphic H3K4 demethylating machinery. …”
Get full text

Bioinformatics Analysis of Transcriptomic Data Reveals Refined Functional Networks for the Self-Renewal of Mouse Spermatogonial Stem Cells by Min Wang, Wene Zhao, Fuqiang Wang, Xiufeng Ling, Daozhen Chen, Tao Zhou, Ying Wang

“…Using a dynamic statistical model, we identified a list of 1119 candidate genes for SSC self-renewal with the best enrichment of canonical markers. Finally, based on interaction relations, we further optimized the list and constructed a refined network containing integrated information of interactions, expression alternations, biological functions, and disease associations. …”
Get full text

Application of Box-Behnken Design in Optimization of Glucose Production from Oil Palm Empty Fruit Bunch Cellulose by Satriani Aga Pasma, Rusli Daik, Mohamad Yusof Maskat, Osman Hassan

“…A three-level Box-Behnken design combined with the canonical and ridge analysis was employed to optimize the process parameters for glucose production from OPEFB cellulose using enzymatic hydrolysis. …”
Get full text

Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis by Yewei Jia, Rui Li, Yixuan Li, Katerina Kachler, Xianyi Meng, Andreas Gießl, Yi Qin, Fulin Zhang, Ning Liu, Darja Andreev, Georg Schett, Aline Bozec

“…HMOX1 was identified as a crucial regulatory factor in this process, directly involved in inducing ferroptosis and affecting osteocyte viability. We uncover a non-canonical pathway that involves excessive autophagy-mediated ferritin degradation, highlighting the complex relationship between autophagy and ferroptosis in melanoma-induced osteocyte death. …”
Get full text

Change detection in the dynamics of an intracellular protein synthesis model using nonlinear Kalman filtering by Gerasimos G. Rigatos, Efthymia G. Rigatou, Jean Daniel Djida

“…It is shown that such a dynamical system satisfies differential flatness properties and this allows to transform it, through a change of variables (diffeomorphism), to the so-called linear canonical form. For the linearized equivalent of the dynamical system, state estimation can be performed using the Kalman Filter recursion. …”
Get full text

Monocyte eukaryotic initiation factor 2 signaling differentiates 17-hydroxy-docosahexaenoic acid levels and pain by Peter R.W. Gowler, Asta Arendt-Tranholm, James Turnbull, Rakesh R. Jha, David Onion, Tony Kelly, Afroditi Kouraki, Paul Millns, Sameer Gohir, Susan Franks, David A. Barrett, Ana M. Valdes, Victoria Chapman

“…QIAGEN ingenuity pathway analysis identified the top ranked canonical biological pathway to be eukaryotic initiation factor 2 (EIF2) signaling (lower activation level in the low 17-HDHA-high pain group compared to the high 17-HDHA-low pain group (Z score −3)), followed by EIF4 and P70S6K signaling pathways and mTOR signaling. …”
Get full text

Analysis of Five Earthy-Musty Odorants in Environmental Water by HS-SPME/GC-MS by Zhen Ding, Shifu Peng, Weiwen Xia, Hao Zheng, Xiaodong Chen, Lihong Yin

“…In addition, the storage time experiment indicated that the concentrations did not change significantly for GSM and 2-MIB if they were stored in canonical environment. In conclusion, the method in this study could be applied for monitoring these five odorants in natural waters.…”
Get full text

Synthesis, H2S releasing properties, antiviral and antioxidant activities and acute cardiac effects of nucleoside 5′-dithioacetates by Miklós Bege, Miklós Lovas, Dániel Priksz, Brigitta Bernát, Ilona Bereczki, Rasha Ghanem Kattoub, Richárd Kajtár, Simon Eskeif, Levente Novák, Jan Hodek, Jan Weber, Pál Herczegh, István Lekli, Anikó Borbás

“…In this work, new cysteine-selective nucleoside-H2S-donor hybrid molecules were prepared by conjugating nucleoside biomolecules with a thiol-activatable dithioacetyl group. 5′-Dithioacetate derivatives were synthesized from the canonical nucleosides (uridine, adenosine, cytidine, guanosine and thymidine), and the putative 5′-thio metabolites were also produced from uridine and adenosine. …”
Get full text

Provincial Administration and Local Nobility in Courland in the Middle of the 19th Century by N. A. Mogilevskii

“…As a result, there was a situation in which the German barons considered themselves bound by personal obligations personally with the Russian monarch. …”
Get full text

The probability of detecting host-specific microbial source tracking markers in surface waters was strongly associated with method and season by Claire M. Murphy, Daniel L. Weller, Tanzy M. T. Love, Michelle D. Danyluk, Laura K. Strawn

“…Between 10% (canine) and 38% (human) of total variance was uniquely attributable to non-methodological factors for any of the fecal sources considered, while between 50% (human) and 84% (canine) of variance could not be attributed to either methodological or non-methodological factors. …”
Get full text

Ambivalent partnership of the Drosophila posterior class Hox protein Abdominal-B with Extradenticle and Homothorax. by Jesús R Curt, Paloma Martín, David Foronda, Bruno Hudry, Ramakrishnan Kannan, Srividya Shetty, Samir Merabet, Andrew J Saurin, Yacine Graba, Ernesto Sánchez-Herrero

“…They strongly diverge from anterior and central class Hox proteins, with a low degree of HD sequence conservation and the absence of a core canonical Pbc interaction motif. Here we explore how Abd-B function interface with that of Exd/Hth using several developmental contexts, studying mutual expression control, functional dependency and intrinsic protein requirements. …”
Get full text

Plant community formation and species distribution pattern in relation to environmental variables in Endiras Natural Forest, northwest Ethiopia by Getinet Masresha, Worku Misganaw, Endale Adamu

“…The relationships between species and environmental variables were evaluated using canonical correspondence analysis (CCA). Seventy-three woody plant species, distributed in 40 families, were documented. …”
Get full text

Integrated Multiscale Latent Variable Regression and Application to Distillation Columns by Muddu Madakyaru, Mohamed N. Nounou, Hazem N. Nounou

“…Commonly used inferential models include latent variable regression (LVR) techniques, such as principal component regression (PCR), partial least squares (PLS), and regularized canonical correlation analysis (RCCA). Unfortunately, measured practical data are usually contaminated with errors, which degrade the prediction abilities of inferential models. …”
Get full text

CALCULATION OF A GLARE STOP FOR TWO-MIRROR EXTRA-FOCAL OBJECTIVE by L. F. Zambrano, N. K. Artyukhina, L. V. Peroza

“…Recently, efforts to improve optical characteristics in canonical mirror systems, including aspherical surfaces and corrective aberration capabilities. …”
Get full text