Identification of Key Genes and Pathways Associated with Age-Related Macular Degeneration by Junyu Zhang, Yu Zhou

“…Furthermore, several significantly enriched biological processes, including cancer, organismal injury and abnormalities, and ophthalmic disease, were identified associated with these DEGs. By analysis of canonical pathway, the phototransduction pathway and atherosclerosis signaling were the top two significant canonical pathways altered in RPE/choroid tissues in human AMD. …”
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Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis by Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav

“…Here we show that Cdx2—a lineage defining transcription factor that binds distinct targets in developing versus adult intestinal epithelial cells—has a preferential affinity for a non-canonical CpG-containing motif in vivo. A higher frequency of this motif at embryonic Cdx2 targets and methylated state of the CpG during development enables selective Cdx2 binding and activation of developmental enhancers and genes. …”
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Autoregulation of the glial gene reversed polarity in Drosophila by Jamie L. Wood, Saroj Nepal, Bradley W. Jones

“…We report that three canonical Repo binding sites (RBSs) are located within the upstream 4.3 kilobase repo cis-regulatory DNA (CRD). …”
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Z. Ivinskis: the first objective researcher of St. Casimir's life by Jonas Boruta

“…Ivinskis was the first to establish the fact that Pope Leo X had not written the bull that canonized Prince Casimir, and that in 1602 Clement VIII merely legalized his cult as saint. …”
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Stress Distribution in 5-Unit Fixed Partial Dentures with a Pier Abutment and Rigid and Nonrigid Connectors with Two Different Occlusal Schemes: A Three-Dimensional Finite Element... by Behnaz Ebadian, Amirhossein Fathi, Shivasadat Tabatabaei

“…Each FPD was analyzed with the canine rise and group function occlusal schemes (a total of 4 models). …”
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Flexibility in PAM recognition expands DNA targeting in xCas9 by Kazi A Hossain, Lukasz Nierzwicki, Modesto Orozco, Jacek Czub, Giulia Palermo

“…This increased flexibility confers a pronounced entropic preference, which also improves recognition of the canonical TGG PAM. Furthermore, xCas9 enhances DNA binding to alternative PAM sequences during the early evolution cycles, while favouring binding to the canonical PAM in the final evolution cycle. …”
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Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis by Sheryl L. Coutermarsh-Ott, John T. Doran, Caroline Campbell, Tere M. Williams, David S. Lindsay, Irving C. Allen

“…Recently, a noncanonical inflammasome has been characterized which functions through caspase-11 and appears to augment many biological functions previously considered to be dependent upon the canonical inflammasome. To better elucidate the function of this noncanonical inflammasome in toxoplasmosis, we utilized Asc−/− and Casp11−/− mice and infected these animals with T. gondii. …”
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CRYSTAL STRUCTURES OF TWO PHOSPHONATE SALTS: MONOCYCLOHEXYLAMMONIUM HYDROGEN PHOSPHONATE AND MONOCYCLOHEXYLAMMONIUM PHENYL PHOSPHONATE by MODOU SARR, MOUHAMADOU BIRAME DIOP, MOUHAMADOU SEMBENE BOYE, AMINATA DIASSE-SARR, PHILIPPE GUIONNEAU

“…In this structure, hydrogen phosphonate anions are linked by pairs through O—H···O hydrogen bonds leading to anionic dimers. …”
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Useful Solutions for Plane Wave Diffraction by Dielectric Slabs and Wedges by Gianluca Gennarelli, Giovanni Riccio

“…This work presents an overview of available uniform asymptotic physical optics solutions for evaluating the plane wave diffraction by some canonical geometries of large interest: dielectric slabs and wedges. …”
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Linear and structural stability of a cell division process model by Vladimir Balan, Ileana Rodica Nicola

“…As well, for these values, the structural stability of the SODE is studied, using the five KCC-invariants of the second-order canonical extension of the SODE, and all the cases prove to be Jacobi unstable.…”
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Equivalence between subshrubs and chaotic bands in the Mandelbrot set by G. Pastor, M. Romera, G. Alvarez, D. Arroyo, F. Montoya

“…From all the denominations of a chaotic band, we show the canonical form; that is, the one associated to the hyperbolic component that generates such a chaotic band. …”
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Johann George Schreiber’s Atlas selectus: new findings by Paprotny Zbigniew

“…Discussed are recently discovered prototype versions of the Atlas which preceded series of “canonical” editions, and status of post-1795 copies. …”
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Invariants de Witt des involutions de bas degré en caractéristique 2 by Tignol, Jean-Pierre

“…A $3$-fold and a $5$-fold quadratic Pfister forms are canonically associated to every symplectic involution on a central simple algebra of degree $8$ over a field of characteristic $2$. …”
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Good Tolerance of Citrate Accumulation due to Plasma Exchange among Patients with Acute-on-Chronic Liver Failure: A Prospective, Observational Study by Yuanji Ma, Yan Xu, Fang Chen, Ying Wang, Lang Bai, Hong Tang

“…Citrate accumulation was defined as the value of total calcium (Catot) to ionized calcium (Caion) ratio (Catot/Caion) greater than or equal to 2.5 (Catot/Caion≥2.5). …”
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Echinococcus granulosus Prevalence in Dogs in Southwest Nigeria by Oyeduntan Adejoju Adediran, Temitope Ubaidat Kolapo, Emmanuel Chibuike Uwalaka

“…Two hundred and seventy-three (273) canine sera were tested for the presence of Echinococcus antigen. …”
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Influence of Added Cellulose Nanocrystals on the Rheology of Polymers by Rajinder Pal, Parth Deshpande, Smit Patel

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Intrinsic Mixed-State Topological Order by Zijian Wang, Zhengzhi Wu, Zhong Wang

“…Specifically, we construct concrete examples by proliferating fermionic anyons in the toric code via local quantum channels. …”
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The Creation of Myth: Starting the First "Great Debate" in International Relations Theory by T. A. Alekseeva

“…From one textbook to another wanders the story about three (sometimes - four) Great debates, which formed the canonical history of the theory of international relations. …”
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Polynomial Solutions to the Matrix Equation X−AXTB=C by Caiqin Song, Jun-e Feng

“…The provided approach does not require the coefficient matrices to be in canonical form. In addition, the numerical example is given to illustrate the effectiveness of the derived method. …”
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