Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury by Wenjun Zhang, Chao Guo, Yi Li, Hao Wang, Huabing Wang, Yingying Wang, Tingting Wu, Huinan Wang, Gang Cheng, Jiangwei Man, Siyu Chen, Shengjun Fu, Li Yang

“…Additionally, FUNDC1 overexpression reversed the effects of LW6 on the altered expression of light chain 3 (LC3) BII and voltage-dependent anion channels as well as blocked the effects of HIF-1α inhibition in cells. …”
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Tissue- and Cell Type-Specific Expression of the Long Noncoding RNA Klhl14-AS in Mouse by Sara Carmela Credendino, Nicole Lewin, Miriane de Oliveira, Swaraj Basu, Barbara D’Andrea, Elena Amendola, Luigi Di Guida, Antonio Nardone, Remo Sanges, Mario De Felice, Gabriella De Vita

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Phase change regulation and enhanced enthalpy in mixed tetrabutylammonium salt hydrates for multi-temperature cold storage applications by Kai Guo, Ziyi Qu, Wenxiang Zhang, Sizhe Zhou, Yonghuan Zang, Xiao Jiang, Zhihan Yang, Qing Xiao, Haojie Gao

“…Further analysis indicated that reducing the molar mass of the mixed anions increased both phase change temperature and enthalpy, with FCS exhibiting a more pronounced improvement. …”
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The influence of monosodium glutamate on the development of oxidative-nitrosative stress in the large cerebral hemispheres of rats under the combination of a change in the “light-d... by O. A. Volkova, O. Ye. Akimov, V. O. Kostenko

“…In a 10 % homogenate of the large cerebral hemispheres, we determined the rate of superoxide anion radical (SAR) production, the content of products that react with thiobarbituric acid (TBA-reactants), their increase, activity of catalase, superoxide dismutase (SOD), ornithine decarboxylase (ODC), concentration of nitrites, peroxynitrites, total activity of NO-synthase (NOS), its constitutive (cNOS) and inducible (iNOS) isoforms. …”
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The necroptosis-related lncRNA ENSG00000253385.1 promotes the progression of esophageal squamous cell carcinoma by targeting the miR-16-2-3p/VDAC1 axis by Xiaoyang Duan, Jian Shi, Ran Hou, Yajie Huang, Chunyan Wang, Huazhen Du

“…The binding sites between miR-16-2-3p and lncRNA ENSG00000253385.1 or voltage-dependent anion channel 1 (VDAC1) were predicted by bioinformatics database and confirmed by dual luciferase reporter gene assay. …”
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Potential Interaction of Pinocembrin with Drug Transporters and Hepatic Drug-Metabolizing Enzymes by Sirima Sangkapat, Rattiporn Boonnop, Jeerawat Pimta, Napason Chabang, Bodee Nutho, Promsuk Jutabha, Sunhapas Soodvilai

“…<b>Methods</b>: The interactions of pinocembrin on drug transporters were determined in the Madin–Darby canine kidney (MDCK) cells overexpressing human (h)OAT1 or hOAT3 and in the Chinese hamster ovary (CHO-K1) cells overexpressing hOCT1, hOCT2, hMATE1, or hMATE2. …”
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Differential coping capacities underlie the overall resistance of temperate seagrasses to herbivory by J. Boada, T. M. Smith, A. M. Ricart, T. Alcoverro, M. Pérez, J. Romero, N. Sanmartí, Y. Ontoria, M. Pierrejen, R. Arthur, D. Alonso, M. P. Adams, F. Rossi

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Redox-Modulating Capacity and Effect of Ethyl Acetate Roots and Aerial Parts Extracts from <i>Geum urbanum</i> L. on the Phenotype Inhibition of the <i>Pseudomonas aeruginosa</i> L... by Lyudmila Dimitrova, Milka Mileva, Almira Georgieva, Elina Tzvetanova, Milena Popova, Vassya Bankova, Hristo Najdenski

“…Antiradical studies, assessed by DPPH, CUPRAC, and ABTS radical scavenging methods and superoxide anion inhibition showed that EtOAcAP extract has effective antioxidant capacity. …”
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Structural insights into the activation mechanism of the human zinc-activated channel by Xuhang Lu, Dongmei Li, Yaojie Wang, Gaohua Zhang, Tianlei Wen, Yue Lu, Nan Jia, Xuedi Wang, Shenghai Chang, Xing Zhang, Jianping Lin, Yu-hang Chen, Xue Yang, Yuequan Shen

“…The hZAC protomer comprises an extracellular domain (ECD) and a transmembrane domain (TMD), sharing more structural similarity with anion-permeable CLRs, such as glycine receptors and type A γ-aminobutyric acid receptors. …”
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Responses of Phospholipase D and Antioxidant System to Mechanical Wounding in Postharvest Banana Fruits by Li Li, Xuemei He, Jian Sun, Changbao Li, Dongning Ling, Jinfeng Sheng, Fengjin Zheng, Guoming Liu, Jiemin Li, Yayuan Tang, Ping Yi, Ming Xin, Zhichun Li, Zhugui Zhou

“…The concentrations of reactive oxygen species (ROS) such as superoxide anion (O2•-) and hydrogen peroxide (H2O2) in fruits increased under mechanical wounding. …”
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Rationally designed universal passivator for high-performance single-junction and tandem perovskite solar cells by Zuolin Zhang, Yinsu Feng, Jike Ding, Quanxing Ma, Hong Zhang, Jiajia Zhang, Mengjia Li, Taoran Geng, Wenhuan Gao, Yang Wang, Boxue Zhang, Thierry Pauporté, Jian-Xin Tang, Hongjian Chen, Jiangzhao Chen, Cong Chen

“…Multiple defects are simultaneously passivated by the synergistic effect of anion and cation. Moreover, the defect healing effect is precisely modulated by carefully controlling the number of hydrogen atoms on cations and steric hindrance. …”
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Exogenous diethyl aminoethyl hexanoate alleviates the damage caused by low-temperature stress in Phaseolus vulgaris L. seedlings through photosynthetic and antioxidant systems by Yu Bai, Qiya Dai, Yanheng He, Li Yan, Jianpo Niu, Xuan Wang, Yongdong Xie, Xuena Yu, Wen Tang, Huanxiu Li, Zhi Huang, Bo Sun, Guochao Sun, Xun Wang, Yi Tang

“…In addition, DA-6 significantly reduced the production rate of superoxide anion radical generation, with a 25.24% reduction in cold-tolerant seedlings and a 49.38% reduction in cold-sensitive seedlings. …”
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Nonlinear Modelling of Kinetic Data Obtained from Photocatalytic Mineralisation of 2,4-Dichlorophenol on a Titanium Dioxide Membrane by Ignazio Renato Bellobono, Roberto Scotti, Massimiliano D'Arienzo, Franca Morazzoni, Riccardo Bianchi, Rodica Stanescu, Cristina Costache, Liliana Bobirica, Gabriela Cobzaru, Paola Maria Tozzi, Mauro Rossi, Mauro Luigi Bonardi, Flavia Groppi, Luigi Gini

“…As has been found previously for other kinds of substrates, modelling of quantum yields for DCP mineralization is consistent with kinetics of hydroxyl radicals reacting between themselves, leading to hydrogen peroxide, other than with substrate or intermediates leading finally to carbon dioxide, paralleled by a second competition kinetics involving superoxide radical anion. For the second series of experiments, on the contrary, the Langmuir-Hinshelwood model was employed. …”
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Crystal structures of zinc(II) coordination complexes with isoquinoline N-oxide by Erin N. Groneck, Nathan Peek, Will E. Lynch, Clifford W. Padgett

“…Finally, complex (V) crystallizes with a pseudo-octahedral geometry; pentaaqua(isoquinoline N-oxide-κO)zinc(II) dinitrate–isoquinoline N-oxide (1/2), [Zn(C9H7NO)(H2O)5](NO3)2·2(C9H7NO). The nitrate ions and non-coordinated iQNO molecules engage in π-stacking and hydrogen-bonding interactions with the coordinated water molecules. …”
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The impact of the National Syphilis Prevention Program on the prevalence of syphilis among people living with HIV in China: a systematic review and meta‐analysis by Qingling Zeng, Yuhui Yang, Limin Zhang, Jiangyu Yan, Jian Wang, Jingmin Nie, Qingmei Wang, Yu Luo, Gaoming Li

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Influence of Irradiance, Flow Rate, Reactor Geometry, and Photopromoter Concentration in Mineralization Kinetics of Methane in Air and in Aqueous Solutions by Photocatalytic Membra... by Ignazio Renato Bellobono, Mauro Rossi, Andrea Testino, Franca Morazzoni, Riccardo Bianchi, Giulia de Martini, Paola Maria Tozzi, Rodica Stanescu, Cristina Costache, Liliana Bobirica, Mauro Luigi Bonardi, Flavia Groppi

“…Kinetics of hydroxyl radicals reacting between themselves, leading to hydrogen peroxide, other than with substrate or intermediates leading to mineralization, were considered, and it is paralleled by a second competition kinetics involving superoxide radical anion.…”
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Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

“…Multivariate analysis determined that the independent risk factors were age, race, norepinephrine, dopamine, phenylephrine, vasopressin, mechanical ventilation, intubation, hepatic failure (HepF), heart rate, respiratory rate, temperature, systolic blood pressure (SBP), anion gap (AG), blood urea nitrogen (BUN), creatinine, chloride, mean corpuscular volume (MCV), red blood cell distribution width (RDW) and white cell count (WCC). …”
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Beyond variance: simple random distributions are not a good proxy for intraspecific variability in systems with environmental structure by Girard-Tercieux, Camille, Vieilledent, Ghislain, Clark, Adam, Clark, James S., Courbaud, Benoit, Fortunel, Claire, Kunstler, Georges, Pélissier, Raphaël, Rüger, Nadja, Maréchaux, Isabelle

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In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

Subjects: “…MT: Non-coding RNAs…”
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Comparative efficacy of incretin drugs on glycemic control, body weight, and blood pressure in adults with overweight or obesity and with/without type 2 diabetes: a systematic revi... by Song Liu, Jiaqiang Hu, Chen Zhao, Hang Liu, Chunyang He

“…For blood pressure management, Tirzepatide significantly reduced systolic blood pressure (MD: -6.69 mmHg, 95% CI: -7.62 to -5.75, P-score: 0.84, p &lt; 0.0001) and diastolic blood pressure (MD: -3.73 mmHg, 95% CI: -4.75 to -2.71, P-score: 0.92, p &lt; 0.0001), with nearly all agents lowering systolic blood pressure by more than 5 mmHg. Non-diabetic participants showed more pronounced improvements in both weight and blood pressure. …”
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