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    Average miniature post-synaptic potential size is inversely proportional to membrane capacitance across neocortical pyramidal neurons of different sizes by Martynas Dervinis, Guy Major

    Published 2025-06-01
    “…The estimated minis’ distributions reveal a striking inverse dependence of mean excitatory mPSP amplitude on total cell membrane capacitance (proportional to cell size, or more exactly, extracellular membrane surface area) suggesting that, in rat somatosensory cortex at least, the average charge injected by single excitatory synapses (ca. 30 fC) is conserved across neocortical pyramidal neurons of very different sizes (across a more than three-fold range).…”
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