Statins for polycystic ovary syndrome in varying resource settings: a phenome-wide association study and evidence synthesis by Laura A. Zahn, Taylor D. Budine, Jana K. Shirey-Rice, Meghan M. Joly, Robert S. Wallis, Gordon R. Bernard, Kenneth J. Holroyd, Jill M. Pulley, Rebecca N. Jerome

“…Through Vanderbilt University Medical Center’s and Repurposing Essential Medicines Internationally program (Project Remedi), we aim to identify novel therapeutic uses for medications already approved and on the World Health Organization’s (WHO) Essential Medicines List (EML). …”
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Fecal sST2 correlates with the disease severity of ulcerative colitis by Jovanović Marina, Gajović Nevena, Jurišević Milena, Simović-Marković Bojana, Marić Veljko, Jovanović Milan, Arsenijević Nebojša, Zdravković Nataša

“…The aim of this study was to determine the fecal values of TNF- α, IL-17, IL-10 and soluble protein ST2 (sST2) in the patients with UC and their relationship with clinicopathological aspects. Methods. The samples of stool of 80 patients with UC were analyzed. …”
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Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traitsResearch in context by Lennart Riemann, Rodrigo Gutierrez, Ivan Odak, Joana Barros-Martins, Lennart M. Roesner, Ximena Leon Lara, Christine Falk, Thomas F. Schulz, Gesine Hansen, Thomas Werfel, Reinhold Förster, Berislav Bošnjak, Felix Jenniches, Norman Klopp, Till Robin Lesker, Martin Stangel

“…Funding: Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy—EXC 2155—project number 390874280.…”
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Sources of shallow natural gases in the Longgang marine gas field, NE Sichuan Basin: an example from the water conveyance tunnel by Shilin Wang, Xiangqian Guo, Peidong Su, Long Li, Mohamed S. Ahmed, Xiaojin Chu, Xiangbing Zhang, Thomas Gentzis, Ahmed Mansour, Ahmed Mansour

“…With the advancement of the Tingzikou Irrigation Area Water Diversion Project, the issue of harmful shallow underground gases in the tunnel has become increasingly prominent. …”
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Glycosyltransferase B3GNT3 promotes immune evasion in pancreatic cancer by downregulating MHC-I levels on the surface of pancreatic cancer cells by Shi-Qi Yin, Hong-Tai Ma, Xia-Qing Li, Shu-Yu Xiao, Aziguli Tulamaiti, Zhi-Gang Zhang, Xin Xing

“…B3GNT3 mRNA levels are significantly higher in tumor samples compared with normal tissue, and its expression is negatively correlated with patient prognosis. …”
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Study on the Surface Water Chemical Composition and Water Quality Pollution Characteristics of the Shiyang River Basin, China by Haifeng Wang, Shaoqing Wu, Jihai Xu, Lixia Zhang, Kuijing Li, Jisheng Li, Heping Shu, Jihua Chu

“…By continuously collecting surface water samples (2000~2024) and utilizing hydrochemical and principal component analysis, the changes in the chemical composition of surface water and its water quality pollution characteristics are examined in the Shiyang River Basin. …”
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Magneto-transport and first principle study of strong topological insulator gray-arsenic by N K Karn, Kapil Kumar, Geet Awana, Kunal Yadav, S Patnaik, V P S Awana

“…The measured residual resistivity ratio ( ρ _300K / ρ _2K ) of the sample is 180, which endorses the high metallic nature of the as-synthesized As single crystal. …”
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Salivary proteomics profiling reveals potential biomarkers for chronic kidney disease: a pilot study by Bianca Uliana Picolo, Nathália Rabello Silva, Mário Machado Martins, Hebréia Oliveira Almeida-Souza, Letícia Cristina Machado de Sousa, Richard Costa Polveiro, Luiz Ricardo Goulart Filho, Robinson Sabino-Silva, Vivian Alonso-Goulart, Luciana Saraiva da Silva

“…Proteomics using saliva is a key strategy for identifying potential disease biomarkers.MethodsWe analyzed the untargeted proteomic profiles of saliva samples from 20 individuals with end-stage kidney disease (ESKD) (n = 10) and healthy individuals (n = 10) using liquid chromatography–tandem mass spectrometry (LC–MS/MS) to identify potential biomarkers for CKD. …”
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Research on Dynamic Mechanical Properties and Numerical Simulation of Broken Coal-Rock Grouting Consolidation Bodies by Jiaxin Huo, Changxing Zhu, Xinming Chen, Jiaqi Guo, Huazhe Jiao, Liyou Zhang, Yu Xu, Mingzhi Wang, Xiangfei Jin

“…The results reveal that increasing grouting pressure enhances the peak stress, transmitted energy, dissipated energy, and toughness of the samples. At optimal grouting pressure (4 MPa), specimens exhibited peak dynamic compressive strength of 24.703 MPa, representing an 18.13% enhancement compared to 1 MPa grouting pressure. …”
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Registry study of immune-related adverse events using electronic patient-reported outcome in patients with cancer receiving immune checkpoint inhibitors: protocol for a multicentre... by Takuhiro Yamaguchi, Tempei Miyaji, Takashi Kawaguchi, Kanako Azuma, Taiki Hirata, Ayako Torii, Hiroaki Usui, Soan Kim, Tatsuya Hayama, Daisuke Hirate, Yosuke Kawahara, Yuki Kumihashi, Tomomi Chisaka, Tetsuya Wako, Akinobu Yoshimura

“…A registry will be established using background information obtained from medical records. The sample size is determined by 1 year projection without using statistical methods. …”
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Lipidomic analyses reveal the dysregulation of oxidized fatty acids (OxFAs) and acyl-carnitines (CARs) in major depressive disorder: a case-control study by Lei He, Na Duan, Chong Wang, Ru Shan, Jing Li, Lin Wang, Qiuli Liu, Junwei Tao, Li Liu, Xiaoliang Ma, Bing Cao

“…Methods The current study was a single-center cross-sectional case-control design. Serum samples were obtained from 107 individuals diagnosed with MDD and 97 healthy controls (HC) aged 18 to 60 years. …”
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Active Galactic Nuclei and Host Galaxies in COSMOS-Web. II. First Look At the Kiloparsec-scale Dual and Offset AGN Population by Junyao Li, Ming-Yang Zhuang, Yue Shen, Marta Volonteri, Nianyi Chen, Tiziana Di Matteo

“…These results generally align with predictions from the ASTRID and Horizon-AGN cosmological simulations, when matching sample selection criteria, implying a high probability of both black holes being active simultaneously in late-stage major mergers.…”
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Quantitative Histopathological Analysis of Cervical Intra-Epithelial Neoplasia Sections: Methodological Issues by Martial Guillaud, Dennis Cox, Anais Malpica, Gregg Staerkel, Jasenka Matisic, Dirk Van Niekirk, Karen Adler‐Storthz, Neal Poulin, Michele Follen, Calum MacAulay

“…Objectives: As part a Program Project to evaluate emerging optical technologies for cervical neoplasia, our group is performing quantitative histopathological analysis of biopsies from 1800 patients. …”
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Pre-vaccination carriage prevalence of Streptococcus pneumoniae serotypes among internally displaced people in Somaliland: a cross-sectional study by Kevin van Zandvoort, Abdirahman Ibrahim Hassan, Mohamed Omer Bobe, Casey L. Pell, Mohamed Saed Ahmed, Belinda D. Ortika, Saed Ibrahim, Mohamed Ismail Abdi, Mustapha A. Karim, Rosalind M. Eggo, Saleban Yousuf Ali, Jason Hinds, Saeed Mohamood Soleman, Rachael Cummings, Catherine R. McGowan, E. Kim Mulholland, Mohamed Abdi Hergeye, Catherine Satzke, Francesco Checchi, Stefan Flasche

“…We collected nasopharyngeal swab samples from 453 residents which were assessed for presence of pneumococci and serotyped using DNA microarray. …”
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Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect: a multistage metabolomic profiling and Mendelian randomization study by Mengyuan Wang, Zhouyi Yin, Hengmin Xu, Zongchao Liu, Sha Huang, Wenhui Wu, Yang Zhang, Tong Zhou, Weicheng You, Kaifeng Pan, Wenqing Li

“…Methods: Plasma metabolites associated with GC risk were identified through a case-control study. Bi-directional two-sample Mendelian randomization analyses were performed to determine potential causal relationships utilizing the Shandong Intervention Trial (SIT), a nested case-control study of the Mass Intervention Trial in Linqu, Shandong province (MITS), China, the UK Biobank, and the FinnGen project. …”
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Investigating the role of job satisfaction and work engagement dynamics in reducing turnover intentions among female bank employees by Nurdjanah Hamid, Wahda Rasyid, Andi Aswan, Insany Fitri Nurqamar, Romi Setiawan, Rianda Ridho Hafizh Thaha

“…AcknowledgmentsThis research represents an internal project by the Faculty of Economics and Business, Hasanuddin University. …”
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Tanshinone Content Prediction and Geographical Origin Classification of <i>Salvia miltiorrhiza</i> by Combining Hyperspectral Imaging with Chemometrics by Yaoyao Dai, Binbin Yan, Feng Xiong, Ruibin Bai, Siman Wang, Lanping Guo, Jian Yang

“…Finally, effective wavelengths were selected using the successive projections algorithm (SPA) and variable iterative space shrinkage approach (VISSA). …”
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Cohort profile: Biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer recurrence and survival – the FOCUS Consortium by Martin Schneider, Ellen Kampman, Alexis Ulrich, Stefanie Brezina, Andrea Gsur, Christopher I Li, William Grady, Andreana N Holowatyj, Biljana Gigic, Eline van Roekel, Anne J M R Geijsen, Arve Ulvik, Jennifer Ose, Janna L Koole, Victoria Damerell, Rama Kiblawi, Tanja Gumpenberger, Tengda Lin, Gry Kvalheim, Torsten Koelsch, Dieuwertje E Kok, Franzel J van Duijnhoven, Martijn J Bours, Andreas Baierl, Kathy Vickers, Nina Habermann, Per Magne Ueland, Matty Weijenberg, Cornelia Ulrich

“…At each time point, sociodemographic data, data on health behaviour and clinical data are collected, blood samples are drawn.Findings to date An increased risk of cancer recurrences was observed among patients with higher compared with lower circulating folic acid concentrations. …”
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Hantavirus antibody seroprevalence and risk factors among adults in West Kazakhstan, 2023 by Ulyana Gubareva, Ulyana Gubareva, Ulyana Gubareva, Roberta Horth, Roberta Horth, Dilyara Nabirova, Dilyara Nabirova, Nur Tukhanova, Nur Tukhanova, Elmira Utegenova, Elmira Utegenova, Zhanna Shapiyeva, Zangar Turliyev, Nazym Tleumbetova, Nurbek Maykanov, Manar Smagul, Alan L. Landay, Gavin Cloherty, Gavin Cloherty, Francisco Averhoff, Francisco Averhoff, Edmond F. Maes

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Application of active learning technique in recognition of diagenetic facies of Mesozoic buried-hill clastic rock reservoirs in Chengdao-Zhuanghai area by ZHANG Pengfei, QIN Feng, WU Songbai, SUN Yaoting, LIU Ruijuan, ZHANG Liqiang, YAN Yiming, MENG Yuan

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