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DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection
Published 2025-04-01“…Remarkably, DPImpute demonstrated accurate SNP imputation from low‐coverage sequencing data from single blood cells and single blastocyst cells, highlighting its potential in embryo GS. …”
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The mechanism of RNA methylation writing protein-related prognostic genes in lung adenocarcinoma based on bioinformatics
Published 2025-06-01“…The identified prognostic genes also play significant roles in immune cell infiltration in LUAD. This study provides new theoretical references for subsequent in-depth research on LUAD.…”
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The possibilities of optical coherence tomography of the anterior segment in the angio mode (AS-OCTA) in the diagnosis and tactics of surgical treatment of corneal diseases
Published 2023-06-01“…Fremont, California, USA) in the «OCT» and «Angio OCT» modes using the AngioVue program and the SSADA algorithm. Results. In the presented clinical cases, the use of AS-OCTA makes possible to accurately assess the depth, area and architectonics of the vessels, and helps to determine the tactics of surgical treatment and type of keratoplasty. …”
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Bone marrow composition features and possibilities of tumor involvement diagnosing in patients with classic Hodgkin’s lymphoma
Published 2023-09-01“…In addition, it was found that the majority of cases with CD20+/± and CD15+/± expression in the primary tumor were observed in the group of patients without bone marrow involvement. when assessing the cellular composition of bone marrow aspirates, it was revealed that in patients with bone marrow tumor infiltration, an increase in cellularity and megakaryocytes number along with a decrease in the plasma cells number is observed. Conclusion. The results suggest further study of bone marrow immunomorphological features in order to identify prognostic factors and search for new therapeutic targets. a more extended analysis of bone marrow aspirate immunomor-phological characteristics using new modern diagnostic methods, minimal residual disease status as a surrogate marker seems to be relevant and necessary to confirm the depth of the antitumor response achieved. …”
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A network-based approach to overcome BCR::ABL1-independent resistance in chronic myeloid leukemia
Published 2025-04-01Get full text
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The orobasal organ (of Ackerknecht) is present in prenatal mice
Published 2025-05-01Get full text
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Ferroptosis plays a role in osteoarthritis
Published 2024-12-01“…Ferroptosis provides a new view of programmed cell death. It is initiated by the oxidation of lipids, reactive oxygen species (ROS) formation and iron buildup within cells, leading to their demise. …”
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The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity
Published 2025-08-01“…Conclusions Formin-like protein 1 is a biomarker of an inflamed tumor microenvironment and positively modulates epithelial–mesenchymal transition and programmed cell death 1 ligand 1 expression in pancreatic cancer, which could be utilized as a novel target for antitumor immunity for more in-depth studies.…”
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Heart Rate, Hematological, and Biochemical Responses to Exercise on Water Treadmill with Artificial River in School Horses
Published 2025-02-01“…WT exercise with AR represents a low-to-moderate intensity aerobic workload for horses, which increases with water depth from fetlock to carpal levels. However, further research is required to evaluate its inclusion in training or rehabilitation programs for athletic horses and its potential beneficial effects.…”
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Acoustic Detection and Quantification of Fish in Lancang Waters of Seribu Islands, Indonesia
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Prospects for Use of Heptral in Hemoblastoses
Published 2008-08-01“…At the same time a hepatocyte, the principal hepatic parenchymal cell, is likely to be the focus of organ pathology. …”
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Genome wide association analysis for body measurements in Jabal Akhdar Omani goats
Published 2025-04-01“…Some of these genes were involved in cell growth (ISM1), early brain development (ADK), and muscle development (ATP2A1). …”
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A bibliometric analysis of research on PD-1/PD-L1 in urinary tract tumors
Published 2024-12-01“…Programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are key components in immune checkpoint studies across various tumors, including those in the urinary tract. …”
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Perencanaan Sistem Informasi Akademik Menggunakan Zachman Framework
Published 2017-04-01“…Analysis of the needs required in the planning of Academic Information System using Zachman Framework approach. Each cell of the matrix Zachman discussed in depth to analyze the needs of Academic Information Systems of SMK Isen Mulang Palangkaraya. …”
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Ferroptosis determinants – potential predictors and therapeutic targets for acute myeloid leukemia
Published 2025-06-01“…Ferroptosis (FP) is a type of non-apoptotic programmed cell death associated with iron-dependent lipid peroxidation. …”
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Small molecule modulation of protein corona for deep plasma proteome profiling
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MODEL OF ORGANIZATION OF KIDNEY CANCER EARLY DIAGNOSIS
Published 2021-05-01“…To improve the early detection of kidney cancer, a prognostic model with computer program for assessing the individual risk of developing kidney cancer was developed. population survey using the ARKC computer program allowed us to narrow the diagnostic search, form risk groups and effectively route patients with suspected kidney cancer for in-depth examination in accordance with the «road map».…”
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Progress in the study of the mechanism of ferroptosis in coronary heart disease and clinical intervention strategies
Published 2025-04-01“…Coronary heart disease (CHD), a serious cardiovascular condition with complex and diverse pathogenesis, has recently seen increased attention to the role of ferroptosis—a novel iron-dependent form of programmed cell death. This review synthesizes current research on ferroptosis mechanisms in CHD and emerging clinical intervention strategies. …”
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Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects
Published 2025-04-01“…Acasunlimab (DuoBody-PD-L1×4-1BB) is an investigational, bispecific antibody designed to elicit an antitumor immune response via conditional 4-1BB activation strictly dependent on simultaneous programmed death-ligand 1 (PD-L1) binding. Since 4-1BB is coexpressed with programmed cell death protein-1 (PD-1) on CD8+ T cells, PD-1 blockade and simultaneous costimulation through 4-1BB may synergistically enhance T-cell effector functions. …”
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