Development and Characterization of Synthetic Allotetraploids Between Diploid Species <i>Gossypium herbaceum</i> and <i>Gossypium nelsonii</i> for Cotton Genetic Improvement by Sevara K. Arslanova, Ziraatkhan A. Ernazarova, Dilrabo K. Ernazarova, Ozod S. Turaev, Asiya K. Safiullina, Abdulqahhor Kh. Toshpulatov, Madina D. Kholova, Laylo A. Azimova, Feruza U. Rafiyeva, Bunyod M. Gapparov, Kuvandik K. Khalikov, Mukhammad T. Khidirov, Abdulloh A. Iskandarov, Davron M. Kodirov, Obidjon Y. Turaev, Salikhjan A. Maulyanov, Joshua A. Udall, John Z. Yu, Fakhriddin N. Kushanov

“…The study establishes a robust framework for utilizing wild <i>Gossypium</i> species to overcome genetic bottlenecks in conventional cotton breeding programs.…”
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Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration by Junyi Xia, Zeyu Zhang, Jinlong Weng, Guanxiong Zhu, Zidan Xu, Liting Zeng, Janak Lal Pathak, Lina Yu

“…Human periodontal ligament stem cells (hPDLSCs) are key to regenerating periodontal tissue, and their osteogenic differentiation ability directly influences the repair and reconstruction of periodontal bone tissue. …”
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Biosafety and biosecurity problems in Ukraine that arise during emergent infections by A. O. Vysotskyi, B. V. Gutyj, O. V. Kozenko, N. Yu. Krempa, I. V. Dvyliuk, N. V. Magrelo, H. V. Klym, T. V. Martyshuk, U. M. Vus

“…The role of international and non-governmental organizations in establishing and improving biosafety and biosecurity standards in veterinary laboratories is described, and the need to create national biosafety programs to combat infectious diseases and the use of effective and innovative alternative imported means of animal protection is demonstrated. …”
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Starting a synthetic biological intelligence lab from scratch by Md Sayed Tanveer, Dhruvik Patel, Hunter E. Schweiger, Kwaku Dad Abu-Bonsrah, Brad Watmuff, Azin Azadi, Sergey Pryshchep, Karthikeyan Narayanan, Christopher Puleo, Kannathal Natarajan, Mohammed A. Mostajo-Radji, Brett J. Kagan, Ge Wang

“…This has increased interest in synthetic biological intelligence (SBI), which involves training in vitro neurons for goal-directed tasks. This multidisciplinary field requires knowledge of tissue engineering, biomaterials, signal processing, computer programming, neuroscience, and AI. …”
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Degradation of PARP1 by MARCHF3 in tumor cells triggers cCAS-STING activation in dendritic cells to regulate antitumor immunity in hepatocellular carcinoma by Qian Wang, Rui Peng, Chi Zhang, Jun Cao, Bingbing Su, Daoyuan Tu, Qiangwei Deng, Guoqing Jiang, Shengjie Jin, Dou-Sheng Bai

“…Mechanistically, we identified MARCHF3 as a pivotal regulator of the DNA damage response. It directly interacted with Poly(ADP-Ribose) Polymerase 1 (PARP1) via K48-linked ubiquitination, leading to PARP1 degradation. …”
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Integrative QTL mapping and candidate gene analysis for main stem node number in soybean by Bire Zha, Chunlei Zhang, Rongqiang Yuan, Kezhen Zhao, Jianqiang Sun, Xiulin Liu, Xueyang Wang, Fengyi Zhang, Bixian Zhang, Sobhi F. Lamlom, Honglei Ren, Lijuan Qiu

“…Abstract Main stem node number (MSNN) is a key yield-related quantitative trait that directly affects the number of branches and seeds per soybean plant. …”
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Dissecting the link between PD-1/PD-L1-based immunotherapy and cancer pain: mechanisms, research implications, and artificial intelligence perspectives by Marco Cascella, Brigida Miranda, Carmen Gagliardi, Lucia Santaniello, Milena Mottola, Alida Mancusi, Laura Ferrara, Federica Monaco, Francesca Gargano, Francesco Perri, Alessandro Ottaiano, Maurizio Capuozzo, Ornella Piazza, Stefano Pepe, Anna Crispo, Agostino Guida, Giovanni Salzano, Giustino Varrassi, Luigi Liguori, Francesco Sabbatino, The TRIAL Group

“…In the last decade, immune checkpoint inhibitor (ICI)-based immunotherapy targeting programmed cell death-1 (PD-1) and its ligand 1 (PD-L1) has revolutionized cancer care. …”
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EIF2AK2 protein targeted activation of AIM2-mediated PANoptosis promotes sepsis-induced acute kidney injury by Siwei Wei, Lei Wu, Zhen Xiang, Xiaoxiao Yang, Dongjie Pei, Liubing Jiang, Zhen Du

“…PANoptosis refers to a type of inflammatory programmed cell death that exhibits key characteristics of apoptosis, necroptosis, and pyroptosis. …”
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Combination therapy with expanded natural killer cells and atezolizumab exerts potent antitumor immunity in small cell lung cancer by Manh-Cuong Vo, Van-Tan Nguyen, Van-Dinh-Huan Tran, Hyung-Joo Oh, Sung-Hoon Jung, Woo Kyun Bae, Je-Jung Lee, In-Jae Oh

“…Natural killer (NK) cells can directly eliminate cancer cells without prior sensitization; this is largely governed by inflammatory cytokines, which serve as killing signals to cancer cells. …”
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Cell biomechanics on muscle atrophy: from intricate mechanisms to therapeutic frontiers by Yilin Wang, Jingyuan Meng, Jiechao Zhang, Lichao Tian, Wenrui Wei, Xiaoye Tang, Qian Zhang, Daofang Ding, Xuepeng Wang, Zicheng Guo, Yong He

“…Moreover, stem‐cell myogenic differentiation is optimized on 3D biomimetic substrates with stiffness from 11 to 17 kPa under physiological loading, and advances in biomaterials and tissue engineering enable more accurate muscle‐tissue models.Future Directions Translating these biomechanical insights into tailored clinical interventions—combining stretch, compression, and shear modalities with biomaterials, stem-cell technologies, and personalized exercise programs— holds promise for preventing and reversing muscle atrophy across diverse patient populations.…”
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Neurological and Olfactory Disturbances After General Anesthesia by Antonino Maniaci, Mario Lentini, Rosario Trombadore, Loris Gruppuso, Santo Milardi, Rosario Scrofani, Giuseppe Cuttone, Massimiliano Sorbello, Rodolfo Modica, Jerome R. Lechien, Paolo Boscolo-Rizzo, Daniele Salvatore Paternò, Luigi La Via

“…This narrative review provides a comprehensive overview of the mechanisms, risk factors, and preventive strategies for neurological and olfactory disturbances after general anesthesia and highlights future directions for research to improve patient outcomes. …”
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Transcriptome analysis reveals the mechanisms underlying petal growth during the flower opening process in Phalaenopsis orchids by Yunxiao Guan, Qiaoyu Zhang, Ting Zhang, Minghe Li, Ye Ai, Junwen Zhai, Siren Lan, Zhong-Jian Liu, Shasha Wu, Donghui Peng

“…Petal size is a vital trait that directly determines flower size and shape of Phalaenopsis. …”
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Estimation and evaluation of iron reserves in the eastern area of Eileh1 mine, Razavi Khorasan province by Hamid Esmati Daroneh, Maryam Gholamzadeh

“…The maximum search radius in the direction of 0° azimuth was 42.6 meters, the average search radius at 90° azimuth was 10.6 meters, and the minimum search radius in the vertical direction (0° azimuth) was 32 meters. …”
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Lower limb biomechanical differences between forehand and backhand forward lunges in amateur female badminton players by Zhonghao Xie, Jing Pan, Xingyu Wu, Huiting Liang, Bosi Chen, Dongping Tan, Meng Wu, Zhiguan Huang

“…In contrast, the forehand lunge demonstrates greater hip stiffness, potentially reflecting an adaptation of the lower limb to varying directional demands. These findings emphasize the importance of incorporating targeted ankle and hip training exercises into conditioning programs.…”
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RESISTANCE TO THE BLAST AGENT AND THE MORPHOBIOLOGICALFEATURES OF GENOTYPES IN THE Oryza sativa L. COLLECTION FROM VARIOUS ECOLOGICAL AND GEOGRAPHICAL GROUPS IN CONDITIONS OF КUBAN... by T. L. Korotenko, O. A. Bragina, I. I. Suprun, Zh. M. Mukhina, Yu. V. Epifanovich, A. A. Petrukhnenko, T. А. Khorina

“…The most common and harmful disease of the agricultural crop rice is a “burn” caused by the fungus Magnoporthe grisea (Hebert) Barr, the causative agent of rice blast. The important direction of modern domestic rice breeding is the development of high-yielding varieties resistant to blast. …”
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Scientific output of undergraduate research supervisors: the role of sex-related, academic career, and subject areas in a Brazilian public institution by Woska Pires da Costa, Angélica Ferreira Melo Walker, Vicente Miñana-Signes, Manuel Monfort-Pañego, Priscilla Rayanne E. Silva Noll, Matias Noll, Matias Noll

“…It focuses on undergraduate research (UR) programs at a Brazilian federal educational institution. …”
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Modern Trends of Radiotherapy Cancer Oral Cavity by V. A. Titova, G. P. Snigireva, V. Y. Petrovsky, E. N. Telisheva

“…At the same time switching on in programs of radiation and combined treatment with chemotherapy (CT) increases effectiveness of traditional methods to 69 %. …”
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Identification of key ferroptosis genes in hepatocellular carcinoma and type 2 diabetes mellitus through bioinformatics analysis by Jinjin Zhou, Yage Shi, Yulun Jian, Yuhan Li, Wenya Yu, Wei Mu, Yang Ge

“…These findings provide new directions for drug development and therapeutic strategies in the future.…”
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Factors affecting medical artificial intelligence (AI) readiness among medical students: taking stock and looking forward by Arash Ziapour, Fatemeh Darabi, Parisa Janjani, Mohammad Amin Amani, Murat Yıldırım, Sayeh Motevaseli

“…Moreover, universities should identify the needs of students based on scientific evidence, and the medical education system should design AI training programs in its educational framework in the same direction.…”
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Unravelling cyberbullying among Egyptian adolescents: the protective influence of self-control and moral identity with gender and socioeconomic dynamics by Basma Elsayed Mohamed Othman, Shymaa Mahmoud Zedan Abdelhai, Mohammed Ibrahim Touni Ibrahim, Alaa Eldin Moustafa Hamed, Abeer Moustafa Barakat, Essam Eltantawy Elsayed

“…Although moral identity did not directly predict cyberbullying, gender moderated its influence (β = -0.221, p = 0.006). …”
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