Targeting p62 by sulforaphane promotes autolysosomal degradation of SLC7A11, inducing ferroptosis for osteosarcoma treatment by Qiuming Zou, Xiaofeng Zhou, Jianqin Lai, Haixia Zhou, Jinxuan Su, Zhijing Zhang, Xiaosong Zhuang, Lili Liu, Ruijie Yuan, Sijia Li, Siyu Yang, Xinyi Qu, Jiezhu Feng, Yongqi Liu, Zisheng Li, Shiting Huang, Zhi Shi, Yu Yan, Zhiming Zheng, Wencai Ye, Qi Qi

“…Ferroptosis, a recently discovered mode of programmed cell death, has been implicated as a potential strategy for cancer therapy. …”
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Challenges and strategies for cultivating young teachers in pathophysiology departments at Chinese medical colleges: a narrative review by Jin Li, Ying Luo, Youxing Li, Yufeng Zhao, Yeli Zhong, Rentong Hu, Bin Zhong, Yanli Li, Shuang Zhao

“…This narrative review examines the challenges, strategies, and future directions in the development of young teachers within the pathophysiology departments of Chinese medical colleges. …”
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Bioethical and Human Right Considerations during COVID-19 Pandemic Period: Reflections of Integrated Oncology Clinical Services from India by Lal P. Madathil, Princy Louis Palatty, Dhanya Sacheendran, Mamatha Jayachander, Thomas George, Arpita Gur, Abhishek Krishna, Russell Franco D'souza, Manjeshwar Shrinath Baliga

“…There were medical concerns such as missed diagnosis, delayed diagnosis, delayed treatment, stoppage of screening programs, and differed follow-ups during the last 2 years of pandemic. …”
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Graduate Teaching Assistants (GTAs): Roles, Perspectives, and Prioritizing GTA Workforce Development Pathways by Claire L. McLeod, Catherine B. Almquist, Madeline P. Ess, Jing Zhang, Hannah Schultz, Thao Nguyen, Khue Tran, Michael Hughes

“…This would invest in the undergraduate student experience and directly support an institution’s educational mission. …”
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Toward Building Model of Business Closure Intention in SMEs: Binomial Logistic Regression by Gelmar García-Vidal, Alexander Sánchez-Rodríguez, Laritza Guzmán-Vilar, Reyner Pérez-Campdesuñer, Rodobaldo Martínez-Vivar

“…Policymakers can use the findings to pair debt relief and liquidity programs with cognitive bias training that helps owners interpret risk signals realistically. …”
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Prevalence of Growth Disorders in a Nationally Representative Sample of Iranian Adolescents According to Socioeconomic Status: The CASPIAN-III Study by Maryam Bahreynian, Mohammad Esmaeil Motlagh, Mostafa Qorbani, Ramin Heshmat, Gelayol Ardalan, Roya Kelishadi

“…These findings underscore the necessity of implementing evidence-based health promotion programs and preventive strategies according to SES.…”
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Identifying and understanding novel ecosystem functions: a scientific approach to nature restoration law by Agnieszka K. Hutniczak, Wojciech Bryś, Roman Dychkovskyi, Renata Gaj, Artur Dyczko, Agnieszka Błońska, Karolina Bierza, Barbara Bacler-Żbikowska, Gabriela Woźniak

“…Key initiatives include the EU Biodiversity Strategy for 2030, EU Habitats Directive, and EU Funding Programs, all of which promote sustainable development and strengthen restoration laws. …”
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The Role of Physical Activity in Managing Urological Health by Hubert Bigajski, Aleksandra Banaś, Maciej Michalik, Piotr Widera, Marta Handschuh, Olga Bilczewska, Justyna Helis, Wiktoria Janik, Paulina Jakubczyk, Aleksandra Buczek

“…Structured prehabilitation programs with pelvic floor muscle training optimize continence outcomes post-surgery. …”
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Injured inflammatory environment overrides the TET2 shaped epigenetic landscape of pluripotent stem cell derived human neural stem cells by Noriko Kamei, Kenneth Day, Wei Guo, Daniel L. Haus, Hal X. Nguyen, Vanessa M. Scarfone, Keith Booher, Xi-Yu Jia, Brian J. Cummings, Aileen J. Anderson

“…We determine that the inflammatory environment overrides epigenetic programming in vitro and in vivo by directly modulating TET2 expression levels in hES-NSC to change cell fate. …”
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Lightweight AES Design for IoT Applications: Optimizations in FPGA and ASIC With DFA Countermeasure Strategies by Salman Ahmed, Nabihah Ahmad, Nasir Ali Shah, Ghulam E. Mustafa Abro, Ardhi Wijayanto, Abdinasir Hirsi, Abdul Rehman Altaf

“…Finally, this study provides valuable insights for finding research directions to strengthen the robustness of AES in lightweight IoT environments.…”
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ngx-mol-viewers: Angular components for interactive molecular visualization in bioinformatics by Damiano Clementel, Damiano Clementel, Alessio Del Conte, Alexander Miguel Monzon, Silvio C. E. Tosatto, Silvio C. E. Tosatto

“…While the primary goal of these databases is to collect and distribute data through application programming interfaces (APIs), providing visualization and analysis tools directly on the browser interface is crucial for users to understand the data, which increases the usefulness and overall impact of the databases. …”
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Limited Effect of Biodiversity on the Multifunctionality of a Revegetated Riparian Ecosystem by Yueliang Jiang, Chen Ye, Manuel Delgado-Baquerizo, Guiyao Zhou, Yu Gong, Quanfa Zhang

“…Revegetation impacted EMF both directly and indirectly via altering the soil properties. …”
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Pumpkin Seeds as a Natural Remedy for Anemia: Nutritional Insights and Therapeutic Potential by Andugula Swapna Kumari, MSc, Gowrishankar Arumugam, MD, Shyamaladevi Babu, MPhil, PhD, Madhan Krishnan, MSc, PhD, Nohini Sandhya Singampalli, M.Sc, Jayanthi Chandramohan, M.Sc

“…Leveraging the therapeutic potential of these natural alternatives, alongside fortified food programs and precise monitoring methods, can significantly contribute to anemia reduction and improve public health outcomes.…”
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Basal cell carcinoma: PD-L1/PD-1 checkpoint expression and tumor regression after PD-1 blockade by Megan Schollenberger, Evan Lipson, William H. Sharfman, Janis M. Taube, Haiying Xu, Aleksandra Ogurtsova, Jessica Esandrio, Mohammed T. Lilo, Patricia Brothers

“…Monoclonal antibodies that block immune regulatory proteins such as programmed death-1 (PD-1) have demonstrated remarkable efficacy in controlling the growth of multiple tumor types. …”
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Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion by Rui Chen, Zongwei Li, Zhihong Fang, Zou Li, Daoyan Yang, Yuan Li, Shurong Liu, Zhiqiang Liu, Rui Liu, Huan Liu

“…This activation promotes phosphorylation of the interferon regulatory factor 7 (IRF7), which binds to the promoter region of SERTA‐containing domain 1 (SERTAD1, also called SEI1) gene to enhance its transcription. The SEI1 directly interacts with the enhancer factors CREB‐binding protein (CBP)/p300 and RNA polymerase II (pol II)‐associated factor 1 (PAF1) complex, promoting transcriptional activity and leading to upregulation of programmed death ligand‐1 (PD‐L1) and immune escape in myeloma. …”
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Knowledge, attitudes, and practices of pregnant and postpartum women regarding stress urinary incontinence by Qin Dong, Shenxian Wan, Ruihua Wang, Sanshan Guo, Hong Shen, Ningjuan Wang, Wenting Cai, Luxi Cai, Wei Zhao

“…Structural equation modeling (SEM) showed knowledge directly influenced attitudes (β = -0.153, p < 0.001), while both knowledge (β = 0.522, p < 0.001) and attitudes (β = -0.128, p = 0.004) significantly impacted practices. …”
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Buserelin shortens the estrus-to-ovulation interval and improves the pregnancy outcomes in gilts treated with a fixed-time artificial insemination by Zhicheng Shi, Zhicheng Shi, Zhicheng Shi, Zhicheng Shi, Zhicheng Shi, Zongyu Wang, Zongyu Wang, Zongyu Wang, Zongyu Wang, Zongyu Wang, Lei An, Lei An, Lei An, Lei An, Lei An, Zhi Li, Linghua Cheng, Yuan Yue, Min Guo, Xiaodong Wang, Haiqing Liu, Li Ren, Jianhui Tian, Jianhui Tian, Jianhui Tian, Jianhui Tian, Jianhui Tian, Qin Li, Qin Li, Qin Li, Qin Li, Qin Li, Shumin Wang, Shumin Wang, Shumin Wang, Shumin Wang, Shumin Wang

“…In the present study, we focused on the estrus-to-ovulation interval, a key component in fertility management programs, and directly compared the follicular dynamics and timing of ovulation, and the subsequent pregnancy outcomes between two well-established GnRH analogs buserelin and gonadorelin. 224 prepubertal Large White gilts, randomly divided into three independent batches, were allotted to this study. …”
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Research advances in immune agonists and their nanoparticles for enhancing the immunotherapeutic efficacy of PD-1 inhibitors in malignancies by Renjie Xia, Renjie Xia, Juan Liang, Jianguo Ma, Jianguo Ma, Xiaoyu Du, Xiaoyu Du, Liangbin Ma, Liangbin Ma, Xiongxiong Han, Xiongxiong Han, Yong Wang, Yong Wang, Jianwei Qin, Long Yan

“…Immune checkpoint blockade (ICB), particularly targeting programmed cell death-1 (PD-1), has revolutionized cancer immunotherapy but remains limited by heterogeneous therapeutic responses and immune-related toxicities. …”
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Nutrition-sensitive value-chain development in Ghana: evidence from the field by Freda Elikplim Asem, Selorm Ayeduvor, Firibu K. Saalia, Matilda Steiner-Asiedu, Nicole Sharon Affrifah, Angela Parry-Hanson Kunadu, Emmanuel Essien

“…Finally, efforts must be directed towards minimizing food waste and improving food safety measures.…”
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Risk Factors and Injury Prevention in the Throwing Athlete by Daniel Kline, P.T., D.P.T, S.C.S., Sarah Kate Fischer, P.T., D.P.T., S.C.S., Garrett S. Bullock, P.T., D.P.T., D.Phil., Michael J. Kissenberth, M.D., Ellen Shanley, P.T., Ph.D., O.C.S., Charles A. Thigpen, P.T., A.T.C., Ph.D.

“…Collectively addressing factors, such as shoulder range of motion and strength deficits, trunk and lower extremity function, and implantation of training programs yields a comprehensive approach to reduce arm injury rates. …”
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