Adipocyte Septin-7 attenuates obesogenic adipogenesis and promotes lipolysis to prevent obesity by Liran Xu, Chao Yang, Kaidan Pang, Ying Zhang, Yu He, Siyu Liu, Huijing Tian, Zehua Shao, Siyu Wang, Xingqian Liu, Ting Li, Yapeng Cao, Luqin Yan, Jinjin Liu, Yanan Wang, Yongxin Li, Wei Zhao, Youhua Wang, Yang Yan, Shengpeng Wang

“…Cytoskeletal remodeling directly impacts adipogenic program, however, the precise mechanism remains poorly understood. …”
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Relaxin mimetic in pulmonary hypertension associated with left heart disease: Design and rationale of Re‐PHIRE by Marcin Ufnal, Kathleen Connolly, Marcus Millegard, Elena Surkova, Marco Guazzi, Diana Bonderman, Justin Ezekowitz, Finn Gustafsson, Michał Ciurzyński, Raquel López Vilella, Tariq Ahmad, Roy Gardner, Pavel Jansa, Sandra vanWijk, Koichiro Kinugawa, Erik Björklund, Zhi‐Cheng Jing, Stephan Rosenkranz

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Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility by Rosalyn W Sayaman, Masaru Miyano, Eric G Carlson, Parijat Senapati, Arrianna Zirbes, Sundus F Shalabi, Michael E Todhunter, Victoria E Seewaldt, Susan L Neuhausen, Martha R Stampfer, Dustin E Schones, Mark A LaBarge

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INnovative Steroid Treatment to reduce Asthma development in children after first-time Rhinovirus-induced wheezing (INSTAR): protocol for a randomised placebo-controlled trial by Maria Vollsæter, Knut Øymar, Svein Arne Nordbø, Tytti Vuorinen, Kari Risnes, Claus Klingenberg, Tuomas Jartti, Henrik Døllner, Anna Partty, Håvard Ove Skjerven, Turid Follestad, Trude Elvebakk, Heidi Jartti, Silje Nerheim, Nina Moe, Johanna Koski, Anita Hofstad, Carina Bjørkvoll Leknessund, Cilla Söderhäll, Erle Sissener, Christopher Stephen Inchley, Jon R Konradsen

“…If proven effective, findings may be implemented directly into paediatric clinical guidelines.Trial registration number NCT03889743.…”
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The potential impact of policies and structural interventions in reducing cardiovascular disease and mortality: a systematic review of simulation-based studies by Olalekan A Uthman, Rachel Court, Seun Anjorin, Jodie Enderby, Lena Al-Khudairy, Chidozie Nduka, Hema Mistry, G J Melendez-Torres, Sian Taylor-Phillips, Aileen Clarke

“…One significant challenge lies in the varied approaches and models each study employed, making direct comparisons difficult. Furthermore, there's a gap in understanding how these policies might influence one another, as the studies did not consider potential interactions between them. …”
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Towards eco-friendly pharmaceuticals: Regulatory and policy approaches for sustainable medicines use by Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Sahab Alkhoujah, Faris El-Dahiyat, Ammar Ali Saleh Jaber, Sa'ed H. Zyoud

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Rapid escalation and release of risks to forest ecosystems triggered by warming: Insights from tree growth synchrony in temperate forests by Liangjun Zhu, Danyang Yuan, J. Julio Camarero, David J. Cooper, Mai-He Li, Shuguang Liu, Xiaochun Wang, Paolo Cherubini

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Harnessing storytelling with medical students and community members to build curiosity and trust: A mixed methods evaluation of a pilot intervention by Rebecca K. Rudel, Nicole D. Kaufmann, Shana A.B. Burrowes, Cheryl Harding, Cara Solomon, Benjamin P. Linas, Mari-Lynn Drainoni, Katherine Gergen Barnett

“…Analysis of focus group discussions identified five themes: 1) The workshop cultivated an open and comfortable environment; 2) Community members desire additional information and direction prior to the program; 3) Training medical students may have a downstream impact, but there is a pressing need to train current providers; 4) The workshop articulates opportunities for community members to assert their strength and empowers them to pursue them; and 5) Dismantling medical mistrust requires ongoing efforts. …”
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Amentoflavone Impedes NF-κB Activation and Mediates Apoptosis Induction in Lung Cancer Cells: An in vitro and in silico exploration by Faiyaz SSM, Ahmad A, Fatima D, Shahid SMA, Kaushik G, Verma C, Tiwari RK, Kumar V

“…These results were further supported by in silico studies, which demonstrated a considerable binding energy score of AMF with NF-κB p65/50 compared with the standard drug (doxorubicin).Conclusion: Thus, it was concluded that AMF exerts potent anticancer effects in NSCLC A549 cells through dual mechanism such as direct inhibition of NF-κB signaling and apoptosis induction combined with its high binding affinity, positions it as a promising therapeutic candidate for NSCLC. …”
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SOURCES OF FINANCING INDUSTRIAL COMPLEX ENTERPRISES by Anzhela Zakhitovna Namitulina, Mikhail Nikolaevich Prokofiev, Nikolay Viktorovich Vorovsky

“…State financing of Russian investment sector is characterized by the following features: the source of the reproduction process started only natural resources, many of which are irreplaceable; scarce resources and limited domestic savings, private investors the opportunity to compensate for the lack of public financial resources to overcome the crisis in investment; risky prospects for attracting investment in the real economy through the securities market; set too high price of credit resources, and for the banks is a high risk of untimely return loans and big enough payback period (for example, in mechanical engineering from 3 to 7 years); the passivity of banks and other credit institutions in the capitalization of financial resources; the low efficiency of investment programs associated with attraction of foreign direct investment; the increased export of capital abroad, estimated at billions of dollarst; the main source of investment in the real sector are own funds of enterprises and organizations (60% of total investments); inadequate legal regulation of investment activities of foreign investors in the Russian economy, which reduces the efficiency of the organization of production and the restructuring of a signifi cant number of companies. …”
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The Mediating Role of Negative Mood Affect in the Relationship Between Perceived Stress and Vulnerability to Insomnia Among Student Pharmacist Shift Workers by Salahuddin MF, I BS, Bugingo R, Spencer D, Manzar MD, BaHammam AS

“…While previous studies have explored their direct relationships, limited evidence exists on the dual role of negative mood affect as both a mediator and a non-mediator in these pathways. …”
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Prevalence of Refractive Errors Among School-Age Children and Adolescents in Saudi Arabia: A Systematic Review and Meta-Analysis by Al Khathami A, Baklola M, Alshehri AA, Alnasser LH, Alshehri RS, Salawi MA, Alwadai RH, Al Ghazwi M, Alanazi AAQ, Alshammari AM, Al-bawah N, Hafez M, Abu Melha A

“…The findings underscore the urgent need for standardized diagnostic protocols, including the use of cycloplegic refraction, and the implementation of school-based vision screening programs.Keywords: myopia, hyperopia, astigmatism, refractive errors, children…”
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Insatisfacción corporal y los trastornos de la conducta alimentaria en estudiantes de una universidad privada: Un estudio correlacional (Body dissatisfaction and eating disorders i... by Edwin Gustavo Estrada-Araoz, Guido Ayay-Arista, José Ricardo Pujaico-Espino, Efraín Humberto Yupanqui-Pino, Armando Yupanqui-Pino, Jair Emerson Ferreyros-Yucra, José Octavio Ruiz-Tejada, Freddy Abel Rivera-Mamani

“…Therefore, it is recommended to implement prevention programs in universities that promote a positive body image and educate about the risks of eating disorders. …”
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Microbiological Analysis of Wild Lowbush Blueberries Harvested in Nova Scotia, Canada for the Fresh Produce Market by Timothy Ells, Nancy Tregunno, Lihua Fan, Michele Elliot, Craig Doucette, Hugh Lyu, Alexa Jollimore

“…However, the pathogen could not be detected by direct plating on selective agar without prior enrichment; this indicated its numbers were low. …”
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Factors associated with participation of breast cancer screening in female residents in China: a systematic review and meta-analysis by Jiayu Liu, Hao Hu, Carolina Oi Lam Ung, Menghuan Song

“…Randomised controlled trials, quasi-experimental studies, and other quantitative studies using logistic regression analysis published from inception to June 12, 2024 were retrieved from PubMed, ScienceDirect, Web of Science, Scopus, and China National Knowledge Infrastructure. …”
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The effect of a systematic multi-dimensional assessment in severe uncontrolled asthma: a literature review and protocol for an investigator-initiated, open-label, randomized-contro... by L. Bult, G. J. Braunstahl, J. G. J. V. Aerts, D. Bänffer, J. S. J. A. van Campen, M. S. van Daalen, Y. van Dooren, U. Flanders, E. S. Geurts, P. P. Hekking, R. Heller - Baan, M. J. A. Jans, J. H. Kappen, R. C. A. Mies, B. Oppedijk, M. de la Roij - Hartmans, S. Van der Sar - Van der Brugge, Y. Türk, E. Vis, R. Wolters, E. C. Vasbinder, J. C. C. M. in ‘t Veen

“…The intervention arm undergoes a 6-week systematic assessment program targeting treatable traits followed by tailored treatment, while the control arm directly receives treatment with biologicals. …”
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Collective Immunity to the Measles, Mumps, and Rubella Viruses in the Kyrgyz Population by Anna Yurievna Popova, Viacheslav Sergeevich Smirnov, Svetlana Alexandrovna Egorova, Zuridin Sharipovich Nurmatov, Angelika Marsovna Milichkina, Irina Victorovna Drozd, Gulzada Saparbekovna Dadanova, Gulnara Dzhumadylovna Zhumagulova, Ekaterina Mikhailovna Danilova, Zharkynbek Orozbekovich Kasymbekov, Victoria Georgievna Drobyshevskaya, Gulsunay Zhumabaevna Sattarova, Oyuna Bayarovna Zhimbaeva, Edward Smith Ramsay, Zhanylay Nuridinovna Nuridinova, Valery Andreevich Ivanov, Altynai Keneshpekovna Urmanbetova, Areg Artemovich Totolian

“…An increase in the number of seronegative individuals observed in recent years has led to an increase in measles incidence. This is directly related to a decrease in collective immunity, which provides protection for the population only in conditions of a high density of immunized individuals and their uniform distribution in the population. …”
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A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis by Stefan Wendt, Ada J. Lin, Sarah N. Ebert, Declan J. Brennan, Wenji Cai, Yanyang Bai, Da Young Kong, Stefano Sorrentino, Christopher J. Groten, Christopher Lee, Jonathan Frew, Hyun B. Choi, Konstantina Karamboulas, Mathias Delhaye, Ian R. Mackenzie, David R. Kaplan, Freda D. Miller, Brian A. MacVicar, Haakon B. Nygaard

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Three-Year Follow-Up Assessment of Anthropogenic Contamination in the Nichupte Lagoon by Jorge Herrera-Silveira, Flor Arcega-Cabrera, Karina León-Aguirre, Elizabeth Lamas-Cosio, Ismael Oceguera-Vargas, Elsa Noreña-Barroso, Daniela Medina-Euán, Claudia Teutli-Hernández

“…The tourist industry in coastal karstic lagoons such as the NLS must have a Wastewater Treatment Program as a compensation measure for the anthropic pressure that is negatively changing the water quality of this highly relevant socio-environmental system.…”
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THE INFLUENCE OF THE AGE ON THE PREVALENCE OF GINGIVAL RECESSION IN PATIENTS WITH PERIODONTITIS by P. Mazur, I. M. Suprunovych

“…All patients underwent a clinical examination using the clinical and instrumental program Florida Probe system. Gingival recession was recorded in the presence of root surface exposure of 1 mm or more. …”
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