-
6001
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells
Published 2024-03-01Get full text
Article -
6002
Filling the Spring Gap in Southern Australia: Seasonal Activity of Four Dung Beetle Species Selected to Be Imported from Morocco
Published 2025-05-01“…The twenty-three successfully established species directly contribute to reducing the environmental impacts from dung accumulation, providing improvements to soil health, pasture productivity and pest fly reduction. …”
Get full text
Article -
6003
-
6004
Proceedings of the 7<sup>th</sup> Asia Dengue Summit, June 2024
Published 2025-05-01Get full text
Article -
6005
Less is more: evaluating the impact of transitions of care pharmacist-led optimization on discharge antibiotic therapy duration in the emergency department
Published 2025-01-01“…The ED represents a high-yield setting for TOC-directed antimicrobial stewardship. …”
Get full text
Article -
6006
MIAT promotes tumor-infiltrating CD8+ T-cell exhaustion and malignant progression of renal cell carcinoma via activating JAK3/STAT3 pathway
Published 2025-07-01“…MIAT knockdown significantly enhanced CD8+ T-cell function with increased perforin and interferon-γ production, while reducing the expression of exhaustion markers programmed cell death protein 1 and T-cell immunoreceptor with Ig and ITIM domains. …”
Get full text
Article -
6007
Surface keratin 1, a tumor-selective peptide target in human triple-negative breast cancer
Published 2025-07-01Get full text
Article -
6008
-
6009
Additional expression of T-cell engager in clinically tested oncolytic adeno-immunotherapy redirects tumor-infiltrated, irrelevant T cells against cancer cells to enhance antitumor...
Published 2024-12-01“…Since CAdVEC treatment initially amplified Ad-specific T cells in patients, we re-direct these virus-specific T cells to target tumor cells by additionally expressing CD44v6.BiTE from CAdTetra. …”
Get full text
Article -
6010
Systematic review of multidrug-resistant Klebsiella pneumoniae in the Arabian Peninsula: molecular epidemiology and resistance patterns
Published 2025-01-01“…This systematic review aims to analyze the emergence of antimicrobial resistance genes in MDR K. pneumoniae across GHC countries.MethodsA systematic search was conducted using PubMed, ScienceDirect, and OpenMD for articles published up to March 15, 2023. …”
Get full text
Article -
6011
Identification of a key locus, qRL8.1, associated with root length traits during seed germination under salt stress via a genome-wide association study in rice
Published 2025-03-01“…The elite haplotypes and varieties identified here can be directly utilized in rice breeding programs. These findings increase our understanding of the genetic mechanisms underlying salt tolerance during early seedling establishment and offer new avenues for developing salt-resistant rice varieties.…”
Get full text
Article -
6012
Exploring the relationship between predicted negative energy balance and its biomarkers of Holstein cows in first-parity early lactation
Published 2025-05-01“…This study demonstrates the utility of MIR-predicted traits for understanding the genetic mechanisms of NEB and its potential for integration into breeding programs, while emphasizing cautious interpretation of these results due to limitations of MIR-predictions of studied traits to represent directly measured traits.…”
Get full text
Article -
6013
Genetic parameters and genome-wide association studies including the X chromosome for various reproduction and semen quality traits in Nellore cattle
Published 2025-01-01“…Abstract Background The profitability of the beef industry is directly influenced by the fertility rate and reproductive performance of both males and females, which can be improved through selective breeding. …”
Get full text
Article -
6014
2-Methoxyestradiol attenuates lung injury induced by chronic intermittent hypoxia via inhibiting the HIF1-α/SLC7A11 pathway
Published 2025-05-01“…ChIP-qPCR confirmed the direct interaction between HIF-1α and SLC7A11 promoter region. …”
Get full text
Article -
6015
-
6016
Therapeutic Potential of Targeting Ferroptosis in Periprosthetic Osteolysis Induced by Ultra-High-Molecular-Weight Polyethylene Wear Debris
Published 2025-01-01“…Mechanistically, wear debris released from the articulating surfaces of a prosthesis initiates local inflammation and several modes of regulated cell death programs, such as ferroptosis, which represents a promising therapeutic target in various chronic inflammatory diseases. …”
Get full text
Article -
6017
The relationship between perceived organizational support and insomnia in psychiatric nurses in China: the mediating role of psychological capital
Published 2025-07-01“…These findings suggest that clinical nursing managers may alleviate insomnia in psychiatric nurses by implementing concrete interventions, such as enhancing organizational support through structured programs, and fostering psychological capital via targeted development initiatives and resilience training. …”
Get full text
Article -
6018
Assessment of cardiovascular risk from the use of an interleukin-1 inhibitor in patients with severe tophaceous gout
Published 2016-03-01“…Statistical analysis was carried out using a package of applied Statistica 10.0 programs (StatSoft/Inc., USA).Results. Examination of the common carotid artery indicated that the median IMT that was 0.83 [0.71; 0.94] mm at baseline decreased to 0.74 [0.69; 0.84] mm by the end of the investigation (p = 0.022). …”
Get full text
Article -
6019
Awareness of the government-introduced universal pension schemes among the adult population in Bangladesh: A nationwide cross-sectional survey
Published 2025-01-01“…Awareness is essential for engagement in any voluntary program and directly impacts its success and sustainability. …”
Get full text
Article -
6020