Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study by Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Paulo Rodrigues-Santos, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Jani Sofia Almeida, Luana Madalena Sousa, Luana Madalena Sousa, Luana Madalena Sousa, Patrícia Couceiro, Patrícia Couceiro, Patrícia Couceiro, Patrícia Couceiro, António Martinho, Joana Rodrigues, Ruben Fonseca, Manuel Santos-Rosa, Manuel Santos-Rosa, Manuel Santos-Rosa, Manuel Santos-Rosa, Manuel Santos-Rosa, Paulo Freitas-Tavares, José Manuel Casanova, José Manuel Casanova, José Manuel Casanova, José Manuel Casanova, José Manuel Casanova

“…Using RECIST1.1 criteria, 68.2% of patients achieved stable disease (SD), while 31.8% exhibited progression disease (PD). …”
Get full text

Luvsandanzanzhaltsan (1639–1704) and his Role in the History of Buddhism in Mongolia by Tsymzhit P. Vanchikova

“…The results of the study allow us to conclude that Lamyn-gegen has made a great contribution into the spread of Buddhism in Mongolia, alongside with distributing Buddhist teaching and achievements of the centuries-old experience of medieval scientific knowledge of the East. …”
Get full text

Level of Physical Activity and its Correlation with Mental Health in Community-dwelling Older Individuals: A Cross-sectional Study by Vipra Paragkumar Dalal, Subhash Khatri

Get full text

Improved Estimation of Aboveground Biomass in Rubber Plantations Using Deep Learning on UAV Multispectral Imagery by Hongjian Tan, Weili Kou, Weiheng Xu, Leiguang Wang, Huan Wang, Ning Lu

“…Meanwhile, the DCNN model derived from the G, R, and NIR spectral bands achieved the highest estimation accuracy (<i>R</i>² = 0.89, <i>RMSE</i> = 6.44 t/ha, <i>MAE</i> = 5.72 t/ha), where it outperformed the other ML methods. …”
Get full text

A Pine Wilt Disease Detection Model Integrated with Mamba Model and Attention Mechanisms Using UAV Imagery by Minhui Bai, Xinyu Di, Lechuan Yu, Jian Ding, Haifeng Lin

“…The final fusion model was validated on a test set, achieving an accuracy of 90.0%, a recall of 81.8%, a map of 86.5%, a parameter counts of 5.9 Mega, and a detection speed of 40.16 FPS. …”
Get full text

Accumulation and Transport of Cd, Pb, As, and Cr in Different Maize Varieties in Southwest China by Qi Liu, Sheng Wang, Jijiang Zhou, Li Bao, Wenbing Zhou, Naiming Zhang

“…The yield of the tested maize varieties ranged from 7377.6 to 11,037.0 kg·hm⁻², with M5 (Haoyu 1511) achieving the highest yield. M2, M4, M5, M9, M10, M21, and M25–28 were identified as suitable varieties with low Cd, Pb, As, and Cr accumulation for popularization in HM-contaminated soils in southwestern China due to their low accumulation of HMs.…”
Get full text

Practice on Metered Dose Inhaler Techniques and Its Associated Factors among Asthmatic Patients at Debre Markos Comprehensive Specialized Hospital, East Gojjam, Ethiopia: A Prospec... by Tadele Asmare, Anteneh Belayneh, Bekalu Dessie

“…A metered-dose inhaler remains the principal route for drug administration, and it has greater advantages over systemic treatment. …”
Get full text

Evidence for direct dopaminergic connections between substantia nigra pars compacta and thalamus in young healthy humans by Giovanni Cirillo, Giuseppina Caiazzo, Federica Franza, Mario Cirillo, Michele Papa, Fabrizio Esposito

“…While histological validation and concurrent PET-MRI remains needed for ultimate proofing of existence, given the potential role of this pathway, the possibility to achieve a good reproducibility of these measurements in humans might enable the monitoring of dopaminergic-related disorders, towards targeted personalized therapies.…”
Get full text

Catheter ablation versus antiarrhythmic drugs with risk factor modification for treatment of atrial fibrillation: a protocol of a randomised controlled trial (PRAGUE-25 trial) by Stepan Havranek, Jiri Jarkovsky, Otakar Jiravský, Pavel Osmancik, Veronika Bulková, Jan Chovančík, Tomáš Roubíček, Dalibor Heřman, Zuzana Čarná, Vladimír Tuka, Martin Matoulek, Martin Fiala, Sylvie Stregl-Hruskova, Adam Latiňák, Jiřina Kotryová

“…After the end of follow-up, data will be available upon request to principal investigator.Trial registration number ClinicalTrials.gov Registry (NCT04011800).…”
Get full text

Characteristics and Differences in the Antler Velvet Microbiota During Regeneration by Yongxiang Li, Yuhang Zhu, Bo Yang, Shaochen Yu, Songze Li, André-Denis G. Wright, Rui Du, Huazhe Si, Zhipeng Li

“…The wound formed by antler velvet shedding can naturally achieve regenerative restoration, but the changes in microbial composition that occur during antler velvet regeneration are largely unknown. …”
Get full text

Factors associated with physical fitness and disparities in population segments among older adults: A cross-sectional study by Yuqin Rao, Jingjing Wang, Kai Li, Fanhui Zheng, Ying Chen, Bo Zhai, Jintao Hong, Chen Wang, Bao Liu, Dao Wang

“…Furthermore, greater marginal effects on achieving higher physical fitness test scores were observed among individuals classified as inactive when engaging in more moderate-to-vigorous activities and exercise. …”
Get full text

Characterization and Selection of WiFi Channel State Information Features for Human Activity Detection in a Smart Public Transportation System by Roya Alizadeh, Yvon Savaria, Chahe Nerguizian

“…The reported classification results show that using only the chirp rate estimated from CSI information as a feature, we achieve precision &#x003D; 83&#x0025;, True Positive <inline-formula> <tex-math notation="LaTeX">$(TP)=94\%$ </tex-math></inline-formula>, True Negative <inline-formula> <tex-math notation="LaTeX">$(TN)= 91\%$ </tex-math></inline-formula> and F1-score &#x003D; 87&#x0025;. …”
Get full text

Exploring the Effect of Sampling Frequency on Real-World Mobility, Sedentary Behaviour, Physical Activity and Sleep Outcomes Measured with Wearable Devices in Rheumatoid Arthritis:... by Javad Sarvestan, Kenneth F. Baker, Silvia Del Din

“…Modern treat-to-target management of rheumatoid arthritis (RA) involves titration of drug therapy to achieve remission, requiring close monitoring of disease activity through frequent clinical assessments. …”
Get full text

Itinerarios para la formación de la ciudadanía de acuerdo con la Agenda 2030. Literatura infantil y ODS / Itineraries for citizenship education in accordance with the 2030 Agenda.... by Lourdes Hernández Delgado, Amando López Valero

“…Furthermore, the presence of the key themes of the 2030 Agenda is noted in both classic and more contemporary texts, with the mission of the mediator being to bring the two together in order to achieve the intended goals. …”
Get full text

Earliness and morphotypes of common wheat cultivars of Western and Eastern Siberia by S. E. Smolenskaya, V. M. Efimov, Y. V. Kruchinina, B. F. Nemtsev, G. Y. Chepurnov, E. S. Ovchinnikova, I. A. Belan, E. V. Zuev, Chenxi Zhou, V. V. Piskarev, N. P. Goncharov

“…The retrospective analysis based on the cultivars’ zoning time included in the “State Register for Selection Achievements Admitted for Usage” brought us to the conclusion that the earliness/lateness of modern Siberian commercial cultivars was not regionally but rather zonally-associated (taiga, subtaiga, forest-steppe and steppe zones).…”
Get full text

Humic acid improves water retention, maize growth, water use efficiency and economic benefits in coastal saline-alkali soils by Ge Li, Yuyang Shan, Weibo Nie, Yan Sun, Lijun Su, Weiyi Mu, Zhi Qu, Ting Yang

“…Appropriate HA application significantly enhanced SWS, RD, PH, LAI, ADM, yield, WUE, and ∆NP. Principal component analysis revealed that the H250 treatment in 2019 and the H50 treatment in 2020 achieved the highest comprehensive rankings. …”
Get full text

Autoencoder Artificial Neural Network Model for Air Pollution Index Prediction by Nor Irwin Basir, Kathlyn Kaiyun Tan, Danny Hartanto Djarum, Zainal Ahmad, Dai-Viet N. Vo, Zhang Jie

“…The results show that the deep sparse autoencoder achieves better prediction accuracy with  and  values of 0.1474 and 0.8331, respectively, compared to 0.1515 and 0.8300 for the shallow sparse autoencoder. …”
Get full text

Designing an educational model based on identity development with an Iranian-Islamic approach for primary school students. by Ali Oladhamzehzadeh, masoumeh oladiyan, Mahmoud Safari

“…The basis of human and national identity means having a common awareness and feeling of belonging to the land of literature, language, religion, past achievements and heritage (Mehrabi Koshki et al, 2016). …”
Get full text

Mathematical modelling and phylodynamics for the study of dog rabies dynamics and control: A scoping review. by Maylis Layan, Simon Dellicour, Guy Baele, Simon Cauchemez, Hervé Bourhy

“…This would represent a significant improvement on past studies and a promising opportunity for canine rabies research in the frame of the One Health concept that aims to achieve better public health outcomes through cross-sector collaboration.…”
Get full text

Providing a General Model for the Successful Implementation of Digital Transformation in Organizations by Haidar Ahmadi, Najme Parsaei, Seyyed Hamed Hashemi, Hamidreza Nematollahi

“…Data collection was primarily conducted through semi-structured interviews with 15 individuals until theoretical saturation was achieved. To further enrich the data, text studies and thematic analysis methods were employed for categorizing and coding the collected data.   …”
Get full text