Chemokine family significance and prognostic value in colorectal cancer by Yi Ding, Yi Ding, Yi Ding, Yinnan Chen, Yinnan Chen, Yinnan Chen, Siyun Xie, Quanpeng Qiu, Quanpeng Qiu, Xiaolong Guo, Yun Feng, Yun Feng, Hongxia Li, Hongxia Li, Fang Zhu, Yaping Liu, Yaping Liu, Yaping Liu

“…This study was rigorously augmented using comprehensive datasets from The Cancer Genome Atlas (TCGA), ensuring a robust analysis of gene expression patterns associated with clinical outcomes.ResultsThrough data analysis, we identified key genes from the chemokine family thought pertinent to CRC outcomes. …”
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Deregulated methylation and expression of PCDHGB7 in patients with non-small cell lung cancer: a novel prognostic and immunological biomarker by Yue Yuan, Yue Yuan, Xin Nie, Jiayi Gao, Jiayi Gao, Yumeng Tian, Yumeng Tian, Liuer He, Liuer He, Xue Wang, Ping Zhang, Junling Ma, Lin Li, Lin Li

“…Its function in lung cancer has not been elucidated.MethodsWe comprehensively investigated PCDHGB7 expression, prognosis, biological function, methylation patterns, and it’s relationship with immune infiltration and immunotherapy response through public datasets (HPA, TCGA, GEO, OncoDB and MEXPRESS). …”
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Effect of ocean acidification on the oxygen consumption of the sea urchins Paracentrotus lividus (Lamarck, 1816) and Arbacia lixula (Linnaeus, 1758) living in CO2 natural gradients by Robert Fernández-Vilert, Robert Fernández-Vilert, Vanessa Arranz, Vanessa Arranz, Marta Martín-Huete, Marta Martín-Huete, José Carlos Hernández, Sara González-Delgado, Sara González-Delgado, Rocío Pérez-Portela, Rocío Pérez-Portela

“…Over the seven days of low pH exposure, distinct patterns in respiration rates were revealed, with both species demonstrating potential for acclimatization. …”
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A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats by Pleydell, David R.J., Ndong Bass, Innocent, Mba Djondzo, Flaubert Auguste, Meta Djomsi, Dowbiss, Kouanfack, Charles, Peeters, Martine, Cappelle, Julien

“…The model predicts that annual birth pulses most likely give rise to annual outbreaks, although more complex dynamic patterns – including skip years, multi-annual cycles and chaos – may be possible. …”
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Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling by Konstantin Okonechnikov, David R. Ghasemi, Daniel Schrimpf, Svenja Tonn, Martin Mynarek, Jan Koster, Till Milde, Tuyu Zheng, Philipp Sievers, Felix Sahm, David T.W. Jones, Andreas von Deimling, Stefan M. Pfister, Marcel Kool, Kristian W. Pajtler, Andrey Korshunov

“…Here, we performed methylation-based DNA profiling and transcriptome RNA sequencing analysis of 80 ST-EPN ZFTA-RELA investigating the clinical significance of various molecular patterns. The principal types of ZFTA-RELA fusions, based on breakpoint location, demonstrated no significant correlations with clinical outcomes. …”
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Hybrid Prophet-NAR Model for Short-Term Electricity Load Forecasting by Winita Sulandari, Yudho Yudhanto, Etik Zukhronah, Isnandar Slamet, Hilman Ferdinandus Pardede, Paulo Canas Rodrigues, Muhammad Hisyam Lee

“…Traditional models like SARIMA and Singular Spectrum Analysis (SSA) have been widely used but often need to capture complex nonlinear patterns and deal with data uncertainties. This study aims to develop and evaluate a hybrid forecasting model that combines the Prophet model with a Neural Network Autoregressive (Prophet-NAR) model, referred to as PropNAR. …”
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Host-symbiont-gene phylogenetic reconciliation by Menet, Hugo, Trung, Alexia Nguyen, Daubin, Vincent, Tannier, Eric

“…The evolution of such systems is approached by phylogenetic reconciliation, which describes the common patterns of diversification between two different levels, e.g. genes and species, or hosts and symbionts for example. …”
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Study Protocol of the Korean EGFR Registry: A Multicenter Prospective and Retrospective Cohort Study in Nonsmall Cell Lung Cancer Patients With EGFR Mutation by Chang Dong Yeo, Dong Won Park, Seong Hoon Yoon, Eun Young Kim, Jeong Eun Lee, Shin Yup Lee, Chang‐Min Choi, In‐Jae Oh, Do Jin Kim, Jeong Seon Ryu, Jae Cheol Lee, Young‐Chul Kim, Tae Won Jang, Kye Young Lee, Seung Hun Jang, Seung Joon Kim, for the Korean EGFR Registry Investigators

“…The study will explore the diagnostic methods for EGFR mutations, clinical outcomes based on treatment modalities, and metastatic patterns in EGFR‐mutated NSCLC patients. Moreover, it will investigate various aspects, including the safety and efficacy of a new third‐generation EGFR tyrosine kinase inhibitor (TKI), lazertinib, approved for both first‐ and second‐line treatments. …”
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An AI recognition method for children's clinical operative pain by skin potential (SP) signal by Mingxuan Huang, Cangcang Fu, Linbo Chui, Jiadong He, Xiaozhi Wang, Jikui Luo, Bin Wu, Yonggang Chen, Shaohua Hu, Jihua Zhu, Yubo Li

“…Objective and rationale: Children's clinical pain phenotypes are complex, and there is a lack of objective biological diagnostic markers and cognitive patterns. Detecting physiological signals through wearable devices simplifies disease diagnosis and holds the potential for remote medical applications. …”
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Pharmacometabolomics Enables Real-World Drug Metabolism Sciences by Fleur B. Nijdam, Marieke A. J. Hof, Hans Blokzijl, Stephan J. L. Bakker, Eelko Hak, Gérard Hopfgartner, Frank Klont, on behalf of the TransplantLines Investigators

“…Lastly, the observed metabolic patterns showed no notable differences between kidney and liver transplant recipients. …”
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Integrative machine learning frameworks to uncover specific protein signature in neuroendocrine cervical carcinoma by Tao Shen, Tingting Dong, Haiyang Wang, Yi Ding, Jianuo Zhang, Xinyi Zhu, Yeping Ding, Wen Cai, Yalan Wei, Qiao Wang, Sufen Wang, Feiyun Jiang, Bin Tang

“…The diagnostic effect of kNsDEPs was validated by a set of predictive models and immunohistochemical staining method. The dysregulation patterns of kNsDEPs were further investigated in other neuroendocrine carcinomas. …”
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Correlation and diagnostic significance of CD4 T cell subsets and NLRP3 inflammasome in ulcerative colitis: the role of the NLRP3/T-bet/GATA3 axis by Yingnan Hu, Jingyi Tang, Dian Yu, Shuo Su, Jintao Fang, Linying Xia, Wenjun Xu, Weihan Zhu, Ninping Song, Fengyong Wang, Dechang Diao, Wei Zhang

“…Enhanced NLRP3 inflammasome activation, indicated by elevated NLRP3, Caspase-1, and IL-1β levels. These molecular patterns, confirmed through correlation analysis and molecular docking, underscored strong correlations among NLRP3, T-bet, and GATA3, supporting the proposed NLRP3/T-bet/GATA3 axis. …”
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Ultrasonography, contrast-enhanced ultrasonography and contrast-enhanced computer tomography features of hepatic sarcomatoid carcinoma and hepatic sarcoma: a retrospective study of... by Xingyun Long, Haiyun Shen, Jie Wu, Han Liu, Danqing Huang, Wentao Kong

“…In CEUS, HSCs consistently showed heterogeneous enhancement patterns, while HSs, particularly hepatic angiosarcoma (HA), demonstrated a higher prevalence of hyperintensity (75%). …”
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Evaluation of rheumatoid arthritis-associated interstitial lung disease in patients treated with JAK inhibitors: a MAJIK-SFR cohort study by Adeline Ruyssen-Witrand, Jacques-Eric Gottenberg, Philippe Dieude, Rene-Marc Flipo, Jerome Avouac, Emanuelle Dernis, Anne Tournadre, Marie-Elise Truchetet, Raphaele Seror, André Ramon, Nicolas Roux, André Basch, Pascal Chazerain, Fabienne Coury-Lucas, Richard Damade, Pierre-Antoine Juge, Thao Pham, Clément Prati, Olivier Brocq, Jean Hugues Salmon, Christian hubert roux, Félicien Triboulet, Charles Leské, Émilie Shipley

“…Non-specific interstitial pneumonia and usual interstitial pneumonia accounted for 46% and 43% of the chest HRCT ILD patterns, respectively. No significant changes in FVC and DLCO were observed during the follow-up period. …”
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Classification of Cigarette Types Using Computer Vision: An Analysis of Smoke Aggregation Features by Shishuan Guan, Lei Jiao, Zengyu Wang, Xiaofei Ji, Hongwei Zheng, Cunfeng Yu, Hongtao Li, Liwen Zheng, Shuaishuai Sun, Qiang Sun, Jun Li, Guangwei Jiang, Kezhi Wu, Erge Lin, Xinlong Zhang

“…This data set contains sequence image data of smoke movement patterns of 51 types of cigarettes, including thick, medium and thin cigarettes. …”
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SVR model and OLCI images reveal a declining trend in phycocyanin levels in typical lakes across Northeast China by Changchun Song, Yipei Xu, Chong Fang, Chi Zhang, Zhuohang Xin, Zhihong Liu

“…Although no significant changes in the annual average PC concentrations were noticed, intra-annual fluctuations were observed. Seasonal patterns in PC concentrations were also observed. The contribution rates of natural and anthropogenic factors were determined using spatiotemporal data on PC concentrations from 2016 to 2022 and redundancy analysis. …”
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Use of Antibiotics in Companion Animals from 133 German Practices from 2018 to 2023 by Roswitha Merle, Leonie Feuer, Katharina Frenzer, Jan-Lukas Plenio, Astrid Bethe, Nunzio Sarnino, Antina Lübke-Becker, Wolfgang Bäumer

“…To address this gap, a study was conducted in Germany to analyze patterns of antibiotic use in dogs and cats. <b>Methods</b>: Antibiotic usage data were obtained from debevet, a cloud-based veterinary practice management software based in Berlin, Germany. …”
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Lateralization study of the basal ganglia, thalamus and supplying arteries in healthy individuals based on structure and connectivity analysis using 7.0T MRI by Hongqin Liang, Yawei Gu, Xiaoqi Yi, Li Kong, Jian Wang, Fajin Lv

“…The connectivity between subregions revealed distinct patterns in the bilateral hemispheres, with a leftward dominance. …”
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A framework for dynamic assessment of soil erosion and detection of driving factors in alpine grassland ecosystems using the RUSLE-InVEST (SDR) model and Geodetector: A case study... by Hucheng Li, Jianjun Chen, Ming Ling, Zizhen Chen, Yanping Lan, Qinyi Huang, Xinhong Li, Haotian You, Feng Wang, Xiaowen Han, Guoqing Zhou

“…Understanding the spatiotemporal patterns and key drivers of soil erosion in alpine grassland regions is crucial for developing effective conservation and restoration strategies in ecologically vulnerable areas. …”
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Insights into quinoa endophytes: core bacterial communities reveal high stability to water stress and genotypic variation by Isaac Maestro-Gaitán, Miguel Redondo-Nieto, Sara González-Bodí, Laura Rodríguez-Casillas, Javier Matías, Luis Bolaños, María Reguera

“…Tissue specificity emerged as a key factor, with seeds maintaining a stable microbial community, while roots exhibited more pronounced shifts, highlighting the tissue-dependent patterns of microbial enrichment. Conclusions The results highlight the stability and conservation of endophytic communities in quinoa seeds, even under varying water conditions and across different genotypes, emphasizing the role of tissue specificity in shaping microbial associations. …”
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