Cellular heterogeneity and communication networks in gastric cancer: Single-cell analysis reveals β-hydroxybutyrylation-associated genes and immune infiltration characteristics by You Hu, Jun Xu, Jian Lv, Yan Qin, Yongda Lu, Fan Cen, Hongbao Yang, Kai Chen, Suhua Xia

“…By analyzing 189,700 single-cell profiles, we identified four distinct malignant epithelial cell subpopulations characterized by unique gene expression patterns. Among these, 20 β-hydroxybutyrylation (Kbhb)-associated genes were identified, including key genes such as MRPL13, LDHB, COX6C, FABP5, and RPS13, which were significantly associated with immune infiltration and tumor microenvironment remodeling. …”
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Effects of uncut refuge management on grassland arthropods – A systematic review by Kitti Révész, Róbert Gallé, Jean-Yves Humbert, Péter Batáry

“…We found several potential drivers behind these patterns, including refuge shape – most commonly strips or blocks – and refuge proportion, typically 10–25 % of the area. …”
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Application and progress of non-invasive imaging in predicting lung invasive non-mucinous adenocarcinoma under the new IASLC grading guidelines by Jinbao Feng, Xiaonan Shao, Jianxiong Gao, Xinyu Ge, Yan Sun, Yunmei Shi, Yuetao Wang, Rong Niu

“…In 2020, the International Association for the Study of Lung Cancer (IASLC) pathology committee proposed a new histological grading system, which offers more precise prognostic assessments by combining the proportions of major and high-grade histological patterns. Accurate identification of lung INMA grading is crucial for clinical diagnosis, treatment planning, and prognosis evaluation. …”
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Inputs-Oriented VRS DEA in dairy farms [version 3; peer review: 2 approved, 1 approved with reservations, 1 not approved] by C. A. Zuniga-Gonzalez, J. L. Jaramillo-Villanueva, N.E Blanco-Roa

“…Results The efficiency distribution among farms using VRS, CRS, and FDH technologies reveals varying patterns. Under VRS and CRS, the majority of farms exhibit high efficiency within the 0 to less than 0.2 range, while FDH displays a broader distribution, with notable efficiency at 1 and across various ranges. …”
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Outcomes and associated factors of cervical human papillomavirus infection among 608 women in Shenzhen, China, 2018–2023 by Zhenghan Lv, Xuesen He, Zhiju Li, Yue Yuan, Xinyi Zhou, Changqing Tu, Yinqi Yang, Yanshan Huang, Lili Yin, Huihui Chen, Yanling Tao, Yanling Tao

“…ObjectiveThis study aimed to uncover the patterns of Human papillomavirus (HPV) infection outcomes in women and assess the risk factors that may affect these outcomes.MethodsA retrospective study was conducted on 608 women who tested positive for HPV-DNA during their initial visit to the outpatient department of Shenzhen Longgang Central Hospital from 2018 to 2023 and who had subsequent HPV-DNA testing as part of their post-visit monitoring. …”
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Structure and immunomodulatory activity of Lentinus edodes polysaccharides modified by probiotic fermentation by Jingjing Liang, Meina Zhang, Xiaohan Li, Yuan Yue, Xiaowei Wang, Mengzhen Han, Tianli Yue, Zhouli Wang, Zhenpeng Gao

“…Methylation analysis and NMR spectra indicated that F-LEP-2a and NF-LEP-2a had similar linkage patterns. Furthermore, their immunomodulatory activities were evaluated with immunosuppressive mice. …”
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Flash flood simulation based on distributed hydrological model in future scenarios by Qi Liu, Nan Zhang, Lingling Wang, Kunxia Yu, Jiayi Wu, Jingqi Wang, Meihong Ma, Meihong Ma

“…Next, design storms with a return period greater than 2 years are allocated into rainfall patterns. By combining the accumulated precipitation with the soil moisture content, different distributed hydrological models are applied to calculate the corresponding flood discharges for different rainfall events. …”
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Analysis of Autonomous Penetration Testing Through Reinforcement Learning and Recommender Systems by Ariadna Claudia Moreno, Aldo Hernandez-Suarez, Gabriel Sanchez-Perez, Linda Karina Toscano-Medina, Hector Perez-Meana, Jose Portillo-Portillo, Jesus Olivares-Mercado, Luis Javier García Villalba

“…To enhance the effectiveness of these tests, Machine Learning (ML) has been integrated, showing significant potential for identifying anomalies across various security areas through detailed detection of underlying malicious patterns. However, pentesting environments are unpredictable and intricate, requiring analysts to make extensive efforts to understand, explore, and exploit them. …”
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Formation and Evolution Mechanisms of Severe Haze Pollution in the Sichuan Basin, Southwest China by Xianyu Yang, Yaqiong Lu, Xinsheng Zhu, Jianjun He, Qi Jiang, Kai Wu, Haolin Wang, Xiaoling Zhang, Shigong Wang

“…Our results reveal the detailed formation mechanism of a severe haze episode in the SCB under the effects of regional transport and synoptic forcing patterns to improve the understanding of haze formation in areas with complex terrain.…”
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Mechanical performance of hybrid double- and step-lap joints in primary metallic aircraft structures: An experimental and numerical approach by Amir Ekladious, John Wang, Nabil Chowdhury, Wing Kong Chiu

“…Aerospace-grade 7075-T6 aluminium alloy was used for the adherends, with film adhesives and fasteners arranged in typical airframe patterns. The three-dimensional finite element (FE) models incorporated non-linear adhesive properties, fastener preload, contact interactions, and frictional forces. …”
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High prevalence of antimicrobial resistance genes in multidrug-resistant-ESBLs-producing Klebsiella pneumoniae post-COVID-19 pandemic by Golnar Rahimzadeh, Shaghayegh Rezai, Ghazal Abbasi, Saman Soleimanpour, Reza Valadan, Laleh Vahedi, Somayeh Sheidaei, Faezeh Sadat Movahedi, Raha Rezai, Mohammad Sadegh Rezai

“…This study evaluated the antibiotic resistance patterns of multidrug-resistant, ESBL-producing Klebsiella pneumoniae in northern Iran after the COVID-19 pandemic. …”
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Distribution and risk assessment of microplastics in a source water reservoir, Central China by Minghui Shen, Yang Li, Liwen Qin, Xudong Chen, Tianyu Ao, Xishu Liang, Kaibo Jin, Yanyan Dou, Juexiu Li, Xuejun Duan

“…This study presents novel findings on the distribution of microplastics in different water layers, providing crucial data support for understanding the migration patterns of microplastics in source water reservoirs and facilitating pollution prevention efforts.…”
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City Health Assessment: Urbanization and Eco-Environment Dynamics Using Coupling Coordination Analysis and FLUS Model—A Case Study of the Pearl River Delta Urban Agglomeration by Xiangeng Peng, Liao Liao, Xiaohong Tan, Ruyi Yu, Kao Zhang

“…Core cities face increasing ecological pressures and inefficient land use patterns. Simulation results, under three distinct policy scenarios—“unconstrained”, “growth machine”, and “compact and intensive usage/urban renewal”—and validated through field research, indicate that urban renewal presents a viable strategy for optimizing land use and mitigating ecological pressures. …”
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Individualized autoregulation-guided arterial blood pressure management in neurocritical care by Jonathan R. Gomez, Bhagyashri U. Bhende, Rohan Mathur, L. Fernando Gonzalez, Vishank A. Shah

“…Utilizing these monitors, researchers have been able to discern CA patterns in several pathological states, such as but not limited to acute ischemic stroke, spontaneous intracranial hemorrhage, aneurysmal subarachnoid hemorrhage, sepsis, and post-cardiac arrest, and they have found CA to be altered in these patients. …”
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Extreme high temperatures and heatwave events across Europe in 2023 by Yuqing Sun, Gensuo Jia, Xiyan Xu

“…Here, we investigated the spatial patterns and seasonal evolution of heatwaves over Europe in 2023. …”
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Parameter influence analysis and optimization of wheel–rail creepage characteristics in high-speed railway curves by Bolun An, Jiapeng Liu, Guang Yang, Feng shou Liu, Tong Shi, Ming Zhai

“…Findings – Key service parameters affecting wheel–rail creepage were identified, including the matching relationship between curve geometry and vehicle speed and rail profile parameters. The influence patterns of various parameters on wheel–rail creepage were revealed through response surface analysis, leading to the establishment of parameter optimization criteria. …”
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ML-Based Self-Optimization Handover Technique for Beyond 5G Mobile Network by Saddam Alraih, Rosdiadee Nordin, Asma Abu-Samah, Ibraheem Shayea, Nor Fadzilah Abdullah

“…The technique is evaluated and validated using different major HO metrics, including Handover Probability (HOP), Handover Failure (HOF), and Handover Ping-Pong (HOPP) across various mobility patterns in B5G, specifically considering an urban environment. …”
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Gradient diffusion entropy corrected ALNS optimization for vegetation topology interaction networks by Shengwei Wang, Hongquan Chen, Yulin Guo, Wenjing Su, Yurong Xu, Shuohao Cui, Zhiqiang Zhou

“…In this study, two characteristics of the vegetation interaction network constructed through density analysis linking land cover and land class transfer space can realize the objectivity of ecosystem simulation: (1) Constructing relationships between vegetation types using spaces where transfer patterns occur as aggregated clusters. (2) Calculation of relationship strength based on density analysis. …”
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Improved Electrochemical Performance of Li1.25Ni0.2Co0.333Fe0.133Mn0.333O2 Cathode Material Synthesized by the Polyvinyl Alcohol Auxiliary Sol-Gel Process for Lithium-Ion Batteries by He Wang, Mingning Chang, Yonglei Zheng, Ningning Li, Siheng Chen, Yong Wan, Feng Yuan, Weiquan Shao, Sheng Xu

“…Analysis of Li1.25Ni0.2Co0.333Fe0.133Mn0.333O2 X-ray diffraction patterns by RIETAN-FP program confirmed the layered α-NaFeO2 structure. …”
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Hydrogen bond interactions of coumarin-153 in molecular solvents: molecular dynamics and principal component analysis by Goloviznina, Kateryna, Dudariev, Dmytro, Miannay, François-Alexandre,  Kalugin, Oleg, Koverga, Volodymyr, Takamuku, Toshiyuki, Vitale, Raffaele, Idrissi, Abdenacer

“…Principal component analysis (PCA) was then performed on these distances to compare the unique structures surrounding donor bond atoms and identify patterns in the interactions between C153 and various solvent, such as acetonitrile, butyrolactone, propylene carbonate, methanol, ethanol, propanol, and butanol.Our findings demonstrate that, when C153 acts as a hydrogen bond donor, the interaction behavior of the H atoms that are close to the N atom and that of the H atom close to the trifluoromethyl F atom of C153 is substantially different. …”
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