Mortality in Antinuclear Antibody-Positive Patients with and Without Rheumatologic Immune-Related Disorders: A Large-Scale Population-Based Study by Uria Shani, Paula David, Ilana Balassiano Strosberg, Ohad Regev, Mohamad Yihia, Niv Ben-Shabat, Dennis McGonagle, Orly Weinstein, Howard Amital, Abdulla Watad

“…Significant predictors of mortality included male gender (39.2% vs. 24.4%, <i>p</i> < 0.001), older age at testing (72.4 ± 13.0 vs. 50.1 ± 17.3 years, <i>p</i> < 0.001), and Jewish ethnicity (89.6% vs. 83.2%, <i>p</i> < 0.001). Certain ANA patterns, such as mitochondrial (and dense fine speckled (DFS-AC2)), were highly predictive of mortality, with aHRs of 36.14 (95% CI 29.78–43.85) and 29.77 (95% CI 26.58–33.34), respectively. …”
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Revealing Land-Use Dynamics on Thermal Environment of Riverine Cities Under Climate Variability Using Remote Sensing and Geospatial Techniques by Nazia Iftakhar, Fakhrul Islam, Mohammad Izhar Hussain, Muhammad Nasar Ahmad, Jinwook Lee, Nazir Ur Rehman, Saleh Qaysi, Nassir Alarifi, Youssef M. Youssef

“…While previous studies have investigated factors influencing land surface temperature (LST) variations, gaps persist in integrating Landsat imagery (7 and 8), meteorological data, and Geographic Information System (GIS) tools to evaluate the thermal effects of specific LULC types, including cooling and warming transitions, and their influence on air temperature under variable precipitation patterns. This study investigates LST variations in Islamabad, Pakistan, from 2000 to 2020 using quantile classification at three intervals (2000, 2010, 2020). …”
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Tenofovir and Doravirine Are Potential Reverse-Transcriptase Analogs in Combination with the New Reverse-Transcriptase Translocation Inhibitor (Islatravir) Among Treatment-Experien... by Alex Durand Nka, Yagai Bouba, Wilfried Rooker Tsapi Lontsi, Davy-Hyacinte Gouissi Anguechia, Georges Teto, Aude christelle Ka’e, Ezechiel Ngoufack Jagni Semengue, Collins Ambe Chenwi, Désiré Takou, Lum Forgwei, Tatiana Anim-Keng Tekoh, Aurelie Minelle Kengni Ngueko, Bernadette Bomgning Fokou, Jeremiah Efakika Gabisa, Michel Carlos Tommo Tchouaket, Willy Leroi TognaPabo, Derrick Tambe Ayuk Ngwese, Jacky Njiki Bikoi, Daniele Armenia, Vittorio Colizzi, Marcel Yotebieng, Nicaise Ndembi, Maria-Mercedes Santoro, Francesca Ceccherini-Silberstein, Carlo-Federico Perno, Alexis Ndjolo, Joseph Fokam

“…Drug resistance mutations (DRMs) were interpreted using Stanford HIVdb.v9, and covariation patterns between M184V and major NRTI/NNRTI DRMs were assessed. …”
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Genetic profiling of extended-spectrum β-Lactamase and carbapenemase-producing Escherichia coli O157:H7 from clinical samples among diarrheal patients in Shashemene, Ethiopia by Shimelis Teshome Ayalneh, Biruk Yeshitela Beshah, Yeonji Jeon, Ashenafi Alemu Wami, Seifegebriel Teshome, Solomon Gebreselassie, Se Eun Park, Mekonnen Teferi, Woldaregay Erku Abegaz

“…This study aimed to investigate the genetic profile of ESBL and carbapenemase coding gene carriage in E. coli O157:H7 from clinical stool samples and evaluate antimicrobial susceptibility patterns. Methods A total of twenty-nine bacterial isolates obtained from diarrheal patients were subjected to conventional culture and phenotypic (Kirby Bauer disc diffusion method) testing for antimicrobial resistance. …”
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Molecular and Transmission Characteristics of Mycobacterium Tuberculosis Strains Among College Students in Beijing, China by Cao X, Li X, Song Z, He P, Zhang R, Teng C, Sun Q, Wang X, Zhao B, Zhang Z, Zhao Y

“…The aim of this study is to analyze the genetic diversity and drug resistance of Mycobacterium tuberculosis strains in college students with tuberculosis in Beijing, revealing the lineage structure and transmission patterns specific to this group.Methods: This study used the hospital’s electronic management system to screen for tuberculosis among college students in Changping District, Beijing, from January 2004 to December 2023. …”
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Pembingkaian Perjuangan Tanah Orang Mentawai Dalam Konflik Kehutanan by Nurhayati Nurhayati, Afrizal Afrizal, Jendrius Jendrius

“…The geographical location and growth patterns have never been touched by human intervention, making the Mentawai forest have a unique composition. …”
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The role of the Hygiene Department of Stephen Bathory University in the development and promotion of Public Health in Vilnius in the years 1922–1939 by Aistis Žalnora

“…Therefore, the purpose of this paper is to reveal the theoretical patterns of hygiene and public health established by the hygienists of the Vilnius Hygiene Department as well as the attempts to apply them in practice. …”
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Distribution and dynamics for the ecological assessment of Asan Wetland through periphyton -a water quality indicator by Sazia Tabassum, C. B. Kotnala, A. K. Dobriyal, Mohammed Salman, Richa Bamola

“…Nitrate levels were moderate, with the highest concentrations in December (1.40–1.55 mg/L) and the lowest in July (0.25–0.35 mg/L), showing similar seasonal patterns across sites. The periphyton was represented in this study by 18 different periphytic taxa that belong to three different classes. …”
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Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments by Ning Ning, Sunandana Chandra, Andriy Moshyk, Divya Patel, Isabella C Glitza Oliva, Jennell Palaia, Leon A Sakkal, Natalia Han, Shardul Odak, Jordana K Schmier

“…Objective This study examined real-world treatment patterns and outcomes in patients with melanoma brain metastasis (MBM) treated with first-line immunotherapy consisting of nivolumab plus ipilimumab or anti-programmed death-1 (PD-1) monotherapy (nivolumab or pembrolizumab) or targeted therapy consisting of BRAF/MEK inhibitors.Design Retrospective chart review study.Setting Academic medical centres, community hospitals and private practice offices.Participants Included patients diagnosed with melanoma with brain metastasis in the USA.Outcome measures The statistical analysis was descriptive in nature. …”
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Malaria prevalence, transmission potential and efficacy of artemisinin-based combination therapy in the Kenyan Central highlands: a zone previously characterized as malaria-free by Francis T. Kimani, Kelvin K. Thiongó, Maureen A. Otinga, Lewis K. Mbabu, Mary N. Ombati, Stanley K. Kitur, Sarah A. Ochieng’, Lucy N. Wachira, Damaris K. Matoke-Muhia, Luna Kamau

“…Abstract Background The current study sought to re-evaluate malaria prevalence, susceptibility to artemisinin-based combination therapy (ACT), transmission patterns and the presence of malaria vectors in the Kikuyu area of the Kenyan Central highlands, a non-traditional/low risk malaria transmission zone where there have been anecdotal reports of emerging malaria infections. …”
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Environmental exposures associated with atopy in a rural community in Gwanda district, Zimbabwe: a cross-sectional study by Vuyelwa Ndlovu, Vuyelwa Ndlovu, Moses Chimbari, Pisirai Ndarukwa, Pisirai Ndarukwa, Elopy Sibanda, Elopy Sibanda

“…IntroductionThe increasing prevalence of allergic diseases in Zimbabwe may be attributed to changing environmental exposure patterns. In this study, we sought to identify the most influential environmental and lifestyle factors that may explain the observed atopy in a rural community in Zimbabwe.MethodsUsing a cross-sectional study, information on a wide array of environmental and lifestyle exposures was self-reported by a sample of participants (children aged &lt;18 years and adults aged ≥18 years) in the Gwanda district, Zimbabwe. …”
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A nursing and midwifery training program in Kathmandu on antimicrobial resistance and stewardship and infection prevention and control: a qualitative and quantitative outcomes and... by Jamuna Tamrakar Sayami, Rakchya Amatya, Kshitij Karki, Deepak Bajracharya, Basudha Shrestha, Sreenidhi Srinivasan, Tyler Prentiss, Anita Shallal, Marcus Zervos, Katie Latack, Linda Kaljee

“…Qualitative data analysis included coding, searches, review of coded texts, and identification of patterns and themes.ResultsAMS and AMR knowledge increased at immediate [1.40 (1.06–1.74) CI 95%] and six-month post-training [0.71 (0.35–1.08) CI 95%]. …”
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Evaluating the Impacts of Procedural and Patient-Specific Factors on the Outcomes of Transcatheter Aortic Valve Implantation (TAVI) by Abilkhair Kurmanaliyev, Rima Braukylienė, Ali Aldujeli, Rassul Zhumagaliyev, Serik Aitaliyev, Ramunas Unikas

“…<i>Conclusions</i>: Procedural factors such as fluoroscopy duration and contrast volume, along with patient-specific attributes including age, left ventricular function, and valve calcification patterns, critically influence TAVI outcomes. These findings emphasize the need for tailored procedural strategies and patient management protocols to mitigate risks and enhance the efficacy of TAVI interventions.…”
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Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions by Martin Škandík, Lara Friess, Guillermo Vázquez-Cabrera, Lily Keane, Kathleen Grabert, Mireia Cruz De los Santos, Mercedes Posada-Pérez, Austeja Baleviciute, Mathilde Cheray, Bertrand Joseph

“…Additionally, four other genes—CAPG, LGALS3BP, NRIP1, and P2RY12—were found to share regulatory patterns in response to both aging and extrinsic activation. …”
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The Possibility or Impossibility of Stock Price Prediction: Evidence from the Petrochemical Industry by Masoud Alizadeh Chamazkoti, Mehdi Fathabadi, Mahmod Mahmodzadeh, Saleh Ghavidel Doostkouei

“…Market participants can engage in effective modeling for stocks that lack efficiency and exhibit predictable behavioral patterns to some extent. This allows them to gain insights into future prices and potentially earn profits.…”
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Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…Among those 21 cases of OM unit patterns 13(61.9%) were successful after FESS. In case of sporadic form 9(69.2%), diffuse polyp form 6(60%), infundibular form 1(33.3%) and spheno-ethmoidal form 2(66.7%) were successful. …”
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The European summer heatwave of 2019 – a regional storyline perspective by T. Klimiuk, P. Ludwig, A. Sanchez-Benitez, H. F. Goessling, P. Braesicke, P. Braesicke, J. G. Pinto

“…We provide evidence that the downscaling of global storyline integrations significantly improved the representation of present-day temperature patterns and reduced errors in daily 2 m temperatures relative to observations from central Europe. …”
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P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion by Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Vanessa Figliuolo, Claudia Lucia Martins Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva

“…Damage-associated molecular patterns (DAMPs) such as UTP and ATP are released from infected cells and, once in the extracellular medium, activate P2 purinergic receptors. …”
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Hydra Radio Access Network (H-RAN): Multi-Functional Communications and Sensing Networks, Initial Access Implementation, and Task-2 Approach by Rafid I. Abd, Daniel J. Findley, Kwang Soon Kim

“…More specifically, a novel <inline-formula> <tex-math notation="LaTeX">$\text {task}_{2}$ </tex-math></inline-formula> is developed in this study to generate a list of recommended beamforming vectors and patterns designed to address the challenges arising from blockage scenarios of <inline-formula> <tex-math notation="LaTeX">$\text {level}_{1}$ </tex-math></inline-formula> in MMW/THz environments.…”
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Correlation of muscle strength, information processing speed and cognitive function in the elderly with cognitive impairment——evidence from EEG by Xin Xin, Qing Liu, Shuqi Jia, Shufan Li, Peng Wang, Xingze Wang, Xing Wang

“…The EEG-specific indicators (B = 0.019, 95% CI: 0.003, 0.047) and information processing speed (B = 0.137, 95% CI: 0.096, 0.292) were found to partially mediate the relationship between grip strength and MoCA scores, with information processing speed exerting a stronger mediating effect.ConclusionSpecific patterns were observed in the EEG of elderly individuals with cognitive impairments, which could objectively assess the risk of cognitive decline in this population. …”
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