Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice by Daniel E. Maidana, Sara Pastor Puente, Catherine Wang, Shivam Chandra, Lucia Gonzalez-Buendia, Eleftherios Paschalis Ilios, Andrius Kazlauskas, Demetrios G. Vavvas

“…Further leukocyte immunophenotyping indicated divergent infiltration patterns, with the TS approach exhibiting higher proportions of neutrophils and macrophages/microglia-like cells, while the TV injections had higher CD45hi CD11b + Ly6G- Ly6C + infiltration. …”
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Employing the concept of stacking ensemble learning to generate deep dream images using multiple CNN variants by Lafta Alkhazraji, Ayad R. Abbas, Abeer S. Jamil, Zahraa Saddi Kadhim, Wissam Alkhazraji, Sabah Abdulazeez Jebur, Bassam Noori Shaker, Mohammed Abdallazez Mohammed, Mohanad A. Mohammed, Basim Mohammed Al-Araji, Abdulkareem Z. Mohmmed, Wasiq Khan, Bilal Khan, Abir Jaafar Hussain

“…Performance of the proposed model was evaluated across three octaves to amplify the maximum possible patterns and features of the base image. The resulting dream-like images contain shapes that reflect elements from the ImageNet dataset on which the above pre-trained models were trained. …”
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Linking Complement C3 and B Cells in Nasal Polyposis by Ulrike Werner, Axel Künstner, Maren Drenckhan, Ralph Pries, Karl-Ludwig Bruchhage, Hauke S. Busch, Claus Bachert, Barbara Wollenberg

“…Expression of complement factors, including C3, C5, and the anaphylatoxin receptors, was analyzed in nasal polyp tissue samples, the corresponding inferior turbinates, and healthy controls using transcriptomic methods and protein measurements. Distinct patterns of complement expression were found in nasal polyps compared to controls, characterized by an increased C3 activation and an increase in C3aR-bearing cells. …”
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Application of large language models in disease diagnosis and treatment by Xintian Yang, Tongxin Li, Qin Su, Yaling Liu, Chenxi Kang, Yong Lyu, Lina Zhao, Yongzhan Nie, Yanglin Pan, Yuanyuan Ji

“…They can enhance diagnostic accuracy by processing vast amounts of patient data and medical literature and have demonstrated their utility in diagnosing common diseases and facilitating the identification of rare diseases by recognizing subtle patterns in symptoms and test results. Building on their image-recognition abilities, multimodal LLMs (MLLMs) show promising potential for diagnosis based on radiography, chest computed tomography (CT), electrocardiography (ECG), and common pathological images. …”
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3D Printed Swordfish‐Like Wireless Millirobot by Xingcheng Ou, Yu Sheng, Jiaqi Huang, Dantong Huang, Xiaohong Li, Ran Bi, Guoliang Chen, Weijie Hu, Shuang‐Zhuang Guo

“…This 20 mm long robot features a streamlined form and magnetically programmable movements, enabling biomimetic locomotion patterns such as straight‐line swimming and turning swimming. …”
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Modeling dynamics on the dance floor with directional swarmalators by Petri Toiviainen, Petri Toiviainen, Joshua S. Bamford, Joshua S. Bamford, Joshua S. Bamford, Marc R. Thompson, Marc R. Thompson

“…It establishes a quantitative framework to dissect how individuals on dance floors self-organize and generate emergent patterns in response to both musical stimuli and visual perception of other dancers. …”
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Complete Mitochondrial Genome of <i>Niphon spinosus</i> (Perciformes: Niphonidae): Genome Characterization and Phylogenetic Analysis by Maheshkumar Prakash Patil, Jong-Oh Kim, Seung Hyun Yoo, Jiyoung Shin, Ji-Young Yang, Kyunghoi Kim, Gun-Do Kim

“…Its nucleotide composition, gene arrangement, codon usage patterns, and tRNA secondary structures are identical with other members of the Percoidei suborder. …”
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DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells by Siti Razila Abdul Razak, Yukihiro Baba, Hiromitsu Nakauchi, Makoto Otsu, Sumiko Watanabe

“…We have been analyzing comprehensive expression patterns of microRNA in human and mouse embryonic stem and induced pluripotent stem cells. …”
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A minimal gene set characterizes TIL specific for diverse tumor antigens across different cancer types by Zhen Zeng, Tianbei Zhang, Jiajia Zhang, Shuai Li, Sydney Connor, Boyang Zhang, Yimin Zhao, Jordan Wilson, Dipika Singh, Rima Kulikauskas, Candice D. Church, Thomas H. Pulliam, Saumya Jani, Paul Nghiem, Suzanne L. Topalian, Patrick M. Forde, Drew M. Pardoll, Hongkai Ji, Kellie N. Smith

“…Putative tumor-reactive cells (pTRC) identified via MANAscore in anti-PD-1-treated lung tumors had higher expression of checkpoint and cytotoxicity-related genes relative to putative non-tumor-reactive cells. pTRC in pathologically responding tumors showed distinguished gene expression patterns and trajectories. Collectively, we show that MANAscore is a robust tool that can greatly enrich candidate tumor-specific T cells and be used to understand the functional programming of tumor-reactive TIL.…”
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Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

“…Abstract Technical limitations have prevented understanding of how growth factor signals are encoded in distinct activity patterns of the phosphoinositide 3-kinase (PI3K)/AKT pathway, and how this is altered by oncogenic pathway mutations. …”
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Multilevel and Spatially Heterogeneous Factors Influencing Poor Households’ Income in a Frontier Minority Area in Northeast China by Binyan Wang, Mark W. Rosenberg, Shijun Wang, Peifeng Yang, Junfeng Tian

“…We conducted a case study of Wangqing County, a frontier minority area in Northeast China to examine spatial patterns and income differentials among poor rural households in this area. …”
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Application of the Box–Behnken Design in the Development of Amorphous PVP K30–Phosphatidylcholine Dispersions for the Co-Delivery of Curcumin and Hesperetin Prepared by Hot-Melt Ex... by Kamil Wdowiak, Lidia Tajber, Andrzej Miklaszewski, Judyta Cielecka-Piontek

“…Notably, a significant improvement in solubility was observed, with formulations exhibiting distinct release patterns for the active compounds. Furthermore, the in vitro permeability through the gastrointestinal tract and blood–brain barrier was enhanced. …”
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Membrana preformativa: Unveiling the unexplored facets of dental development by Sakshi Sikaria, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

“…This study aims to provide detailed insights into the expression patterns and functional significance of Ki67 and Cyclin D1 in tooth development. …”
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A two-step machine learning approach for predictive maintenance and anomaly detection in environmental sensor systems by Saiprasad Potharaju, Ravi Kumar Tirandasu, Swapnali N. Tambe, Devyani Bhamare Jadhav, Dudla Anil Kumar, Shanmuk Srinivas Amiripalli

“…. • Provides actionable insights through anomaly visualization, revealing patterns in sensor performance.…”
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Quantifying intratumoral biomarker heterogeneity in tubo-ovarian high-grade serous carcinoma to optimize clinical translation by Aline Talhouk, Derek S. Chiu, Liliane Meunier, Kurosh Rahimi, Cécile Le Page, Monique Bernard, Diane Provencher, David G. Huntsman, Anne Marie Mes Masson, Martin Köbel

“…Markers were stained on tissue microarrays and scored using a continuous or categorical interpretation of staining patterns. Two-way random effect and nested intraclass correlation were used to assess continuous markers, and Gwet’s AC1 was used for categorical markers. …”
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Extreme migratory connectivity and apparent mirroring of non-breeding grounds conditions in a severely declining breeding population of an Afro-Palearctic migratory bird by Máire Kirkland, Nathaniel N. D. Annorbah, Lee Barber, John Black, Jeremy Blackburn, Michael Colley, Gary Clewley, Colin Cross, Mike Drew, Oliver J. L. Fox, Vicky Gilson, Steffen Hahn, Chas Holt, Mark F. Hulme, John Jarjou, Dembo Jatta, Emmanuel Jatta, Kevin Leighton, Ernestina Mensah-Pebi, Chris Orsman, Naffie Sarr, Roger Walsh, Leo Zwarts, Robert J. Fuller, Philip W. Atkinson, Chris M. Hewson

“…Extremely low levels of population mixing were also detected, so any impacts on this population on the non-breeding grounds are unlikely to be shared with more distant breeding populations, corresponding to the observed patterns of European population change. According to a species distribution model using independent field data, this population’s non-breeding grounds had lower suitability than others and likely declined before the period we were able to assess. …”
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Genome biology of long non-coding RNAs in humans: A virtual karyotype by Alessandro Palma, Giulia Buonaiuto, Monica Ballarino, Pietro Laneve

“…Additionally, we observed that lncRNAs generally exhibit shorter gene lengths and fewer splicing variants compared to protein-coding transcripts, with a subset displaying pronounced clustering patterns that may indicate functional relevance. Finally, we identified several clinically associated and experimentally validated SNPs impacting lncRNA genes (lncGs). …”
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Fine-scale forest classification with multi-temporal sentinel-1/2 imagery using a temporal convolutional neural network by Rongfei Duan, Chunlin Huang, Peng Dou, Jinliang Hou, Ying Zhang, Juan Gu

“…A Temporal Convolutional Neural Network (TempCNN), which excels in handling temporal data and adapting to complex patterns, was constructed using TensorFlow with 133.8k parameters. …”
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Incentivizing Demand-Side Response Through Discount Scheduling Using Hybrid Quantum Optimization by David Bucher, Jonas Nuslein, Corey O'Meara, Ivan Angelov, Benedikt Wimmer, Kumar Ghosh, Giorgio Cortiana, Claudia Linnhoff-Popien

“…We implement DSR through discount scheduling, which involves offering discrete price incentives to consumers to adjust their electricity consumption patterns to times when their local energy mix consists of more renewable energy. …”
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Integrated multi-omics analysis reveals the underlying molecular mechanism for the neurotoxicity of triclosan in zebrafish by Shasha Zhao, Yuhang Ling, Baohua Zhang, Danting Wang, Limei Sun

“…Transcriptomics indicated that immune- and metabolism-related gene expression patterns were severely disturbed by TCS. Metabolomic analysis revealed 82 distinct metabolites in adult zebrafish exposed to TCS. …”
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