Single cell RNA sequencing improves the next generation of approaches to AML treatment: challenges and perspectives by Zahra Khosroabadi, Samaneh Azaryar, Hassan Dianat-Moghadam, Zohreh Amoozgar, Mohammadreza Sharifi

“…However, scRNA-seq applications face various challenges such as a large amount of data for high-dimensional analysis, technical noise, batch effects, and finding small biological patterns, which could be improved in combination with artificial intelligence models.…”
Get full text

Central Interleukin-1β Suppresses the Nocturnal Secretion of Melatonin by A. P. Herman, J. Bochenek, K. Król, A. Krawczyńska, H. Antushevich, B. Pawlina, A. Herman, K. Romanowicz, D. Tomaszewska-Zaremba

“…Nocturnal melatonin secretion patterns could be disturbed in pathophysiological states, including inflammation, Alzheimer’s disease, and depression. …”
Get full text

Expression of Neutral Endopeptidase, Endothelin-1, and Nuclear Factor Kappa B in Prostate Cancer: Interrelations and Associations with Prostate-Specific Antigen Recurrence after R... by Panagiotis J. Vlachostergios, Foteini Karasavvidou, Grigorios Kakkas, George Moutzouris, Anna Patrikidou, Ioannis A. Voutsadakis, Danai D. Daliani, Elias Zintzaras, Michael D. Melekos, Christos N. Papandreou

“…There seems to be a clinical model of NEP/NPs and NFκB pathways interconnection, with their constituents following inverse patterns of expression in accordance with their biological roles and molecular interrelations.…”
Get full text

Effects of climate change on wet and dry spells in Kelantan River basin using physically-based hydrological model and CMIP6 scenarios by Nurul Afiqah Mohamad Arbai, Masayasu Irie

“…The climate scenarios of SSP5–8.5 and SSP3–7.0 resulted in the wettest and driest conditions in terms of annual and monthly effective precipitation and discharge patterns. It was predicted that the basin would experience the wettest and driest from 2051 to 2075. …”
Get full text

Last digit tendency: Lucky numbers and psychological rounding in mobile transactions by Hai Wang, Tian Lu, Yingjie Zhang, Yue Wu, Yiheng Sun, Jingran Dong, Wen Huang

“…The distribution of digits in numbers obtained from different sources reveals interesting patterns. The well-known Benford’s law states that the first digits in many real-life numerical data sets have an asymmetric, logarithmic distribution in which small digits are more common; this asymmetry diminishes for subsequent digits, and the last digit tends to be uniformly distributed. …”
Get full text

Surviving prematurity: retrospective longitudinal study of multisystem consequences in preterm-born individuals from infancy to adolescence by Ruta Morkuniene, Ruta Levuliene, Vilmantas Gegzna, Egle Marija Jakimaviciene, Janina Tutkuviene

“…Unique and highly individual patterns of disease co-occurrence were observed, increasing in complexity as BW decreased. …”
Get full text

A Novel Method for Predicting Urban Residential Quality Distribution Based on Multi-Interest Consideration by Jiawen Ren, Xin Zhou, Jingjing An, Xing Shi, Xing Jin, Tianzhen Hong, Da Yan

“…Simulating and predicting urban patterns enables evidence-based decision-making for urban planners. …”
Get full text

Investment preferences of institutional investors in Indonesia: A comparative analysis of pressure-sensitive and pressure-insensitive groups by Dwi Prastowo Darminto, Abdulloh Mubarok, Nurmala Ahmar

“…The period was chosen because it captures a stable economic period in Indonesia, allowing for an accurate assessment of investment patterns without major external shocks. The results reveal that institutional investors favor stocks listed on the Indonesia Shariah Stock Index (ISSI), perceived as low-risk investments. …”
Get full text

Intention to utilize mental health and suicide prevention resources in a community sample during the first year of the COVID-19 pandemic by Lisa J. Cohen, Rawad El Hayek, Benedetta Imbastaro, Inna Goncearenco, Sifan Zheng, Megan L. Rogers, Maurizio Pompilli, Igor Galynker

“…Conclusions Specific demographic populations demonstrate greater interest in mental health care during the COVID-19 pandemic. These help-seeking patterns can be explained in part by an elevated level of SCS symptoms, suggesting greater levels of distress were driving expressed intention to utilize service referrals.…”
Get full text

Demographic Trends in Korean Native Cattle Explained Using Bovine SNP50 Beadchip by Aditi Sharma, Dajeong Lim, Han-Ha Chai, Bong-Hwan Choi, Yongmin Cho

“…In the present study LD patterns and effective population size (Ne) of three Korean cattle breeds along with Chinese, Japanese and Mongolian cattle were compared using the bovine Illumina SNP50 panel. …”
Get full text

Heteronuclear Fe-Mn Cyclopentadienyl Complexes Supported on Boehmite. Thermochemistry and Thermodynamics of their Decomposition by A.I. Rustamova, R.M. Muradxanov, S.N. Osmanova, F.K. Pashayeva, A.N. Mammadov, D.B. Tagiyev, E.H. Ismailov

“…The XRD data show that when calcining at 873 K the boehmite samples with the applied compounds of the above composition and containing these compounds less than 10 wt.%, the diffraction patterns show only reflections characteristic of poorly crystallized aluminum oxide. …”
Get full text

The Reproducibility of Indoor Air Pollution (IAP) Measurement: A Test Case for the Measurement of Key Air Pollutants from the Pan Frying of Fish Samples by Ki-Hyun Kim, Yong-Hyun Kim, Bo-Won Kim, Jeong-Hyeon Ahn, Min-Suk Bae, Richard J. C. Brown

“…If the results were evaluated by an arbitrary criterion of 10%, the patterns were divided into two data groups (e.g., <10% for benzene and some aldehydes and >10% for the remainders). …”
Get full text

Research on Groundwater Drought and Sustainability in Badain Jaran Desert and Surrounding Areas Based on GRACE Satellite by Xiaojun Liu, Naiang Wang, Yixin Wang, Nan Meng, Yuchen Wang, Bin Qiao, Rongzhu Lu, Dan Yang

“…The analysis reveals the spatiotemporal patterns of groundwater drought and sustainability, as well as the underlying factors affecting regional groundwater sustainability. …”
Get full text

The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review by Xue Zhao, Qing Han, Yujia Liu, Chenglin Sun, Xiaokun Gang, Guixia Wang

“…Factors influencing BCAA level can be divided into four parts: race, gender, dietary patterns, and gene variants. These factors might not only contribute to the elevated BCAA level but also show obvious associations with insulin resistance. …”
Get full text

Hydrothermal synthesis of pristine nickel diselenide (NiSe2) and Co induced nickel diselenide (NiCoSe2) nanoparticles with enhanced electrochemical behaviour for supercapacitor app... by S. Saranya, S. Suthakaran, S. Dhanapandian, A. Dinesh, Rajendra P. Patil, Manikandan Ayyar, Lalitha Gnanasekaran, S. Santhoshkumar

“…The prepared NPs were examined using the XRD, FT-IR, SEM/EDX, TEM/SAED, XPS, VSM and cyclic voltammetry (CV) analysis. XRD patterns confirmed the cubic crystal structure of the prepared samples. …”
Get full text

Gene Profiles in the Early Stage of Neuronal Differentiation of Mouse Bone Marrow Stromal Cells Induced by Basic Fibroblast Growth Factor by Lili Yu, Wei Hong, Haijie Yang, Yin Yan Xia, Zhiwei Feng

“…To identify the genes regulating neuronal differentiation, cDNA microarray analysis was conducted using mRNAs isolated from cells differentiated for different time periods (0, 4, 24, and 72 h) after bFGF treatment. Various expression patterns of neuronal genes were stimulated by bFGF. …”
Get full text

Non-negligible Occurrence of Errors in Gender Description in Public Data Sets by Jong Hwan Kim, Jong-Luyl Park, Seon-Young Kim

“…When we analyzed the gender description and the methylation patterns of gender-specific probes (glucose-6-phosphate dehydrogenase [G6PD], ephrin-B1 [EFNB1], and testis specific protein, Y-linked 2 [TSPY2]) in 5,611 samples produced using Infinium 450K HumanMethylation arrays, we found that 19 samples from 7 datasets were erroneously described. …”
Get full text

CT-sensitized nanoprobe for effective early diagnosis and treatment of pulmonary fibrosis by Jiwei Hou, Qijian Ji, Tianyu Tang, Yonger Xue, Lin Gao, Li Dai, Jinbing Xie

“…The distinct honeycombing patterns observed in computed tomography (CT) for the primary diagnosis of PF are typically only visible in patients with moderate to severe disease, often leading to missed opportunities for early intervention. …”
Get full text

Plasma from hypertensive pregnancy patients induce endothelial dysfunction even under atheroprotective shear stress by Sarah Viana-Mattioli, Miriam Helena Fonseca-Alaniz, Iguaracy Pinheiro-de-Sousa, Ricardo Rosa Junior, Moises Henrique Mastella, Ricardo de Carvalho Cavalli, Valeria Cristina Sandrim

“…Previous in vitro studies have not considered the impact of in vivo elements, such as the different patterns of blood flow, and laminar (LSS) vs. oscillatory (OSS) shear stress, on the development of ED. …”
Get full text

HGeoKG: A Hierarchical Geographic Knowledge Graph for Geographic Knowledge Reasoning by Tailong Li, Renyao Chen, Yilin Duan, Hong Yao, Shengwen Li, Xinchuan Li

“…Statistical analysis reveals significant regional heterogeneity and long-tail distribution patterns in HGeoKG-MHT-670K. Furthermore, extensive geographic knowledge reasoning experiments on HGeoKG-MHT-670K show that most knowledge graph embedding (KGE) models fail to achieve satisfactory performance. …”
Get full text