Polymorphisms of Tumor Necrosis Factor-α, Transforming Growth Factor-β, and Interleukin-10 in Asthma Associated with Olive Pollen Sensitization by Blanca Cárdaba, David Calzada, Selene Baos, Miriam Aguerri, Joaquín Quiralte, Carlos Lahoz

“…Sensitization to specific olive pollen-allergens (Ole e 2 and 10) has been correlated with a clinical pattern of asthma. This study analyzes the association between several polymorphims of TNFA (G-308A, C-857T, and C-1031T), IL10 (C-571A and A-1117G), and TGFB (C-509-T) and these sensitizations. …”
Get full text

Secondary Syphilis Presenting as Glossodynia, Plaques en Prairie Fauchée, and a Split Papule at the Oral Commissure: Case Report and Review by Walter de Araujo Eyer-Silva, Maria Alessandra Leite Freire, Cecília Angelina Horta-Araujo, Guilherme Almeida Rosa da Silva, Jorge Francisco da Cunha Pinto, Fernando Raphael de Almeida Ferry

“…Examination revealed painful, shallow erosions on the posterior aspect of the tongue, in a pattern of plaques en prairie fauchée. A painful split papule (fausse perlèche or false angular cheilitis) was also present in the left commissure. …”
Get full text

Insulin autoimmune syndrome in a 3-year-old boy: the youngest to date in China and a narrow review by Ming Cheng, Yuan Ding, Dongmei Wang, Chunxiu Gong

“…Most of these patients presented with unconsciousness initially and their episodes of hypoglycemia do not follow a definitive pattern. Adjustments in diet serve as an effective intervention, and spontaneous remission is relatively common. …”
Get full text

The Effect of Hyperbaric Oxygen Therapy on Functional Impairments Caused by Ischemic Stroke by Emily R. Rosario, Stephanie E. Kaplan, Sepehr Khonsari, Garrett Vazquez, Niyant Solanki, Melanie Lane, Hiriam Brownell, Sheila S. Rosenberg

“…However, the physiological biomarkers showed a pattern of more transient changes following HBOT treatment. …”
Get full text

Molecular Mechanism of Macrophage Activation by Red Ginseng Acidic Polysaccharide from Korean Red Ginseng by Se Eun Byeon, Jaehwi Lee, Ji Hye Kim, Woo Seok Yang, Yi-Seong Kwak, Sun Young Kim, Eui Su Choung, Man Hee Rhee, Jae Youl Cho

“…According to pharmacological evaluation with specific enzyme inhibitors, Western blot analysis of intracellular signaling proteins and inhibitory pattern using blocking antibodies, ERK, and JNK were found to be the most important signaling enzymes compared to LPS signaling cascade. …”
Get full text

Assessing the stability of psychobiological stress reactivity during adolescence: mixed-effect modelling of cortisol responses to laboratory stressors [version 2; peer review: 2 ap... by Elizabeth Susman, Jen O'Shea, Samantha Dockray

“…It is associated with rapid development in the hypothalamus, which is central in the production of both stress and sex steroids. While patterns of stress reactivity are calibrated in early life, this time of rapid development may provide a means for these patterns to change. …”
Get full text

The composition of peripheral immunocompetent cell subpopulations and cytokine content in the brain structures of mutant Disc1-Q31L mice by M. M. Gevorgyan, S. Ya. Zhanaeva, E. L. Alperina, T. V. Lipina, G. V. Idova

“…Thus, Disc1-Q31L mice are characterized by changes in the pattern of cytokines in the brain structures, an amplification of the peripheral T-cell link with an increase in the content of the subpopulations of CD3+CD4+ T helpers and CD3+CD4+CD25+ T regulatory cells, as well as elevated immune reactivity to antigen in the spleen.…”
Get full text

The Surface Heat Flow of Mars at the Noachian–Hesperian Boundary by Javier Ruiz, Laura M. Parro, Isabel Egea-González, Ignacio Romeo, Julia Álvarez-Lozano, Alberto Jiménez-Díaz

“…Currently available remote sensing data are crucial for understanding the Martian heat loss pattern and its global thermal state in this transitional period. …”
Get full text

Multitarget Effects of Danqi Pill on Global Gene Expression Changes in Myocardial Ischemia by Qiyan Wang, Hui Meng, Qian Zhang, Tianjiao Shi, Xuefeng Zhang, Mingyan Shao, Linghui Lu, Jing Wang, Wei Wang, Chun Li, Yong Wang

“…The objective of this study is to systematically characterize altered gene expression pattern induced by myocardial ischemia (MI) in a rat model and to investigate the effects of DQP on global gene expression. …”
Get full text

Perspective: Current Scientific Evidence and Research Strategies in the Role of Almonds in Cardiometabolic Health by Paula R Trumbo, Jamy Ard, France Bellisle, Adam Drewnowski, Jack A Gilbert, Ronald Kleinman, Anoop Misra, John Sievenpiper, Maha Tahiri, Karol E Watson, James Hill

“…A number of research gaps on almond consumption and cardiometabolic health were identified that should be addressed to further understand their role in the various cardiometabolic endpoints, including the mechanisms of action interactions with the microbiome with regular consumption and their role as part of a healthy dietary pattern for both individuals and the general population.…”
Get full text

Mutated p53 Promotes the Symmetric Self-Renewal of Cisplatin-Resistant Lung Cancer Stem-Like Cells and Inhibits the Recruitment of Macrophages by Yu Xu, Zhi Xu, Qi Li, Liang Guo, Yao Wang, Jianchun Zhou, Guansong Wang, Yuliang Liu

“…CD44+/CD90+ stem-like cells were identified in above cisplatin-resistant lung cancers (termed as cisplatin-resistant lung cancer stem-like cells, (Cr-LCSCs)) and stained with PKH26 dye which was used to define the self-renewal pattern. The proportion of symmetric divisions was significantly higher in Cr-LCSCs with mutant (mt) p53 compared with Cr-LCSCs with wild-type (wt) p53, and forced expression of mt p53 promoted the symmetric division of Cr-LCSCs. …”
Get full text

Cross-Modal Augmented Transformer for Automated Medical Report Generation by Yuhao Tang, Ye Yuan, Fei Tao, Minghao Tang

“…Unlike previous methods that rely on coarse-grained features without human intervention, our method introduces a “locate then generate” pattern, thereby improving the interpretability of the generated reports. …”
Get full text

Simulation and response mechanism of potential geographical distribution of plateau pika Ochotona curzoniae under climate change by Yanni Song, Hainan Chong, Dawei Wang, Haijun Xiao

“…The central and eastern parts of the QTP are potential distribution areas for plateau pika, with the current suitable area totaling 8.01 × 105 km2, accounting for 32.04 % of the QTP. 3) The suitable areas of plateau pika will gradually migrate to higher altitude areas, especially with more significant changes under high-emission scenarios (SSP370 and SSP585). 4) Human activities have relatively limited impacts on the distribution pattern of plateau pika, mainly manifested as suitability changes in some local areas. …”
Get full text

Effects of Furrow Corn Straw Mulch on Soil Erosion and Organic Carbon Loss in Sloping Farmland in the Black Soil Region by Haiou Shen, Hongli Li, Hang Liu, Jialong Wu, Chunli Li, Yushi Liang

“…The mean organic carbon concentration both in runoff and sediment decreased in the following order: II > III > I > T1 > T2. Rainfall pattern II induced greater ratios of organic carbon loss. …”
Get full text

How can urban expansion and ecological preservation be balanced? A simulation of the spatial dynamics of production-living-ecological spaces in the Huaihe River Eco-Economic Belt by Tonghui Yu, Shanshan Jia, Yu Zhang, Xufeng Cui

“…Future expansions of living space are expected to be prominent, following a radial expansion pattern from urban centers to peripheral areas. Overall, considering the vulnerability of production space to further encroachment, future strategies for the Huaihe River Eco-Economic Belt should prioritize protecting high-quality farmland and critical ecological zones, while regulating urban expansion and strengthening land-use planning to ensure PLES sustainability. …”
Get full text

Dynamic changes in betanin content during the growing season of table beet: their interplay with abiotic factors by D. V. Sokolova

“…Recommendations are given concerning the choice of a planting pattern and the timing of table beet harvesting for pigment extraction.…”
Get full text

GIS and remote sensing based assessment of West Rapti River channel migration in Nepal by Sandesh Gharti, Prabin Poudel, Ramesh Silwal, Suchana Baniya, Jeetendra Gautam, Om Mishra, Sijan Bista, Dipendra Dhungana

“…The study shows the river is naturally multi-channeled and exhibits a braided pattern with sinuosity index values ranging from 1.02 to 1.38, indicating highly braided conditions during 2010 and 2015. …”
Get full text

Spatial and Temporal Distribution of Nanoflare Heating during Active Region Evolution by Biswajit Mondal, James A. Klimchuk, Amy R. Winebarger, P. S. Athiray, Jiayi Liu

“…The spatial distribution of heating frequencies across the AR reveals a clear pattern: the core of the active region spends most of its time in a low-frequency heating state, the periphery is dominated by high-frequency heating, and the region between the core and periphery experiences intermediate-frequency heating.…”
Get full text

Transparent memory tests with even repeating addresses for storage devices by V. N. Yarmolik, I. M. Mrozek, V. A. Levantsevich, D. V. Demenkovets

“…The maximum diagnostic ability of new tests is shown for the case of the simplest faults, such as constant (SAF) and transition faults (TF), as well as for complex pattern sensitive faults (PNPSFk). There is a significantly lower time complexity of the March_pA_1 and March_pA_2 tests compared to classical transparent tests, which is achieved at the expense of less time spent on obtaining a reference signature. …”
Get full text

Psychological distress and coping strategies among Indonesian psychologists during the COVID-19 pandemic: a two-wave cross-lagged study by Fitri Ariyanti Abidin, Ahmad Gimmy Prathama, Efi Fitriana, Evy Sulfiani Komala, Joeri K. Tijdink

“…Notably, maladaptive coping strategies demonstrated a similar pattern, predicting the continued use of maladaptive coping techniques over time, but they were also consistently associated with psychological distress across both time points, though they did not significantly predict future psychological distress.Discussion: These findings shed light on the dynamic nature of coping strategies and psychological distress among psychologists, presenting significant implications for their support systems and mental health during the challenges posed by the pandemic. …”
Get full text