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    Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme by Stephen J Walters, Daniel Hind, Richard M Jacques, Steven A Julious, Joanne Rothwell, Oscar Bortolami, Laura Flight, Inês Bonacho dos Anjos Henriques-Cadby, Christopher Knox, Ben Nadin, Michael Surtees

    Published 2017-03-01
    “…Many trials fail to reach their planned sample size within the envisaged trial timescale and trial funding envelope.Objectives To review the consent, recruitment and retention rates for single and multicentre randomised control trials funded and published by the UK's National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme.Data sources and study selection HTA reports of individually randomised single or multicentre RCTs published from the start of 2004 to the end of April 2016 were reviewed.Data extraction Information was extracted, relating to the trial characteristics, sample size, recruitment and retention by two independent reviewers.Main outcome measures Target sample size and whether it was achieved; recruitment rates (number of participants recruited per centre per month) and retention rates (randomised participants retained and assessed with valid primary outcome data).Results This review identified 151 individually RCTs from 787 NIHR HTA reports. …”
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  15. 995

    Daily feeding frequency impacts muscle characteristics and fat deposition in finishing pigs associated with alterations in microbiota composition and bile acid profile by Luga Hu, Huayu Tang, Zhaoxi Xie, Hongyu Yi, Lunjie Feng, Pan Zhou, Yong Zhang, Jingbo Liu, Xiang Ao, Jianchuan Zhou, Honglin Yan

    Published 2025-01-01
    “…Therefore, this study aimed to explore the effects of feeding frequency on muscle growth, fat deposition, cecal microbiota composition, and bile acid composition in finishing pigs.MethodsSixteen Sichuan-Tibetan black pigs, with an initial weight of 121.50 ± 1.60 kg, were divided into two groups and fed either two meals (M2) or four meals (M4) per day. …”
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    Maximizing the performance of heat stressed broilers by optimizing starch-to-lipid ratios, digestible amino acid, and metabolizable energy during the finisher phase by Dilshaan Duhra, Denise Beaulieu, Tory Shynkaruk, Juliano C. de Paula Dorigam, Rose Whelan, Karen Schwean-Lardner

    Published 2025-02-01
    “…A {3,3} simplex lattice design was used to assess relative effects and generate predictive models. Three basal finisher diets were formulated to have the highest S:L ratio (Basal A; 20:1), DigLys (Basal B; 1.30 %), or AME (Basal C; 3300 kcal/kg). …”
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