The Dose-Dependent Effects of Spironolactone on TGF-β1 Expression and the Vulnerability to Atrial Fibrillation in Spontaneously Hypertensive Rats by Mirong Tang, Yan Chen, Fuqing Sun, Liangliang Yan

“…Compared with group C, the myocardial cell size, atrial fibrosis, TGF-β1 expression, P-wave duration, PR interval, AERP, inducibility, and duration of atrial fibrillation in group H were conspicuously increased (p < 0.05); compared with group H, there was no significant difference in the myocardial cell size, atrial fibrosis, TGF-β1 expression, and electrophysiological indexes in group SH upon spironolactone intervention (p > 0.05); compared with group H, the myocardial cell size, atrial fibrosis, the expression of TGF-β1, P-wave duration, PR interval, the inducibility, and duration of atrial fibrillation in the group SL and group SM were all decreased (p < 0.05); compared with group SM, the effect in the group SL was more prominent (p < 0.01). Conclusion. Hypertension can lead to cardiomyocyte hypertrophy, deposition of interstitial fibrosis in myocardial tissue, and an increase in the vulnerability to atrial fibrillation. …”
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Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling by Bisha Ding, Jie Li, Jia-Lin Yan, Chun-Yan Jiang, Ling-Bo Qian, Jie Pan

“…Natural killer group 2 member D (NKG2D) is a prominent activating receptor of NK cell. UL16-binding protein 2 (ULBP2), always expressed or elevated on cancer cells, functions as a key NKG2D ligand. …”
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Prognostic significance of p27 in colorectal cancer: a meta-analysis and bioinformatics analysis by Jing Zou, Dong Wang, Gaoping Yin, Kexiang Lu, Kaibin Chang, He Li

“…In addition, we used Gene Expression Profiling Interactive Analysis (GEPIA), University of Alabama at Birmingham’s Cancer Data Analysis Portal (UALCAN), and the Human Protein Atlas (HPA) to validate our results.ResultsThrough an extensive examination of four prominent databases, a total of 21 original articles encompassing a cohort of 3,378 patients were identified. …”
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Public Health Messaging on Twitter During the COVID-19 Pandemic: Observational Study by Ashwin Rao, Nazanin Sabri, Siyi Guo, Louiqa Raschid, Kristina Lerman

“… BackgroundEffective communication is crucial during health crises, and social media has become a prominent platform for public health experts (PHEs) to share information and engage with the public. …”
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Balneotherapy for the treatment of post-COVID syndrome: a randomized controlled trial by Diana Ovejero, Anna Ribes, Judit Villar-García, Marta Trenchs-Rodriguez, Daniel Lopez, Xavier Nogués, Robert Güerri-Fernandez, Natalia Garcia-Giralt

“…Among these, SF-36’s energy/fatigue and pain subscales exhibited the most prominent changes with a Beta-coefficient [95%CI] of -17.45 [-24.23;-10.66] and − 21.634 [-30.48;-12.78], respectively (p-value < 0.0001). …”
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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…Language developmental delays were more prominent than motor. Autism, epilepsy, movement disorders, sleep disturbances, and various psychiatric behaviors constituted the core of the disorder’s clinical phenotype. …”
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E. W. Godwin’s Month in Normandy: Travel Writing as Intertext by Richard W. Hayes

“…As would be expected of one of England’s prominent Gothic Revival architects, Godwin concentrated on the important examples of medieval architecture he encountered in what was a combined holiday and sketching tour. …”
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Bokvalg i norske barnehager - hva som leses sammen med barn og hvorfor by Agnes-Margrethe Bjorvand, Monica G. Mitchell, Katarzyna A. Tunkiel, Marianne Undheim

“…Furthermore, the book selection is heavily dominated by older texts and book series, which makes it challenging for newer individual titles to gain prominence. According to the teachers, they tend to choose books that they know the children enjoy. …”
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مدى وعى أعضاء هیئة التدریس بجامعة المنوفیة بالانتحال العلمى : دراسة استکشافیة by د. السید رجب الأسرج

“…Given the great importance of information technology today in all areas,especially the use of the Internet because of its many facilities, a new type ofcrime was violated that violates the sanctity and privacy of this information via theInternet and they are what is known as scientific plagiarism, scientific theft, orinformation piracy, and that is in The Arab scientific community witnessed thespread of many unhealthy phenomena, the most prominent of which is thescientific theft phenomenon of Arab intellectual production, which has becomeone of the most dangerous negative phenomena experienced by university andresearch societies and institutions in Egypt and the Arab world, and has evenbecome one of The ugliest crimes common in our current society. …”
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Assessment of genetic diversity in Sehima nervosum for yield, nutritional traits and ensiling quality by Sultan Singh, Tejveer Singh, Neeraj Kumar, Pushpendra Koli, Madan Mohan Das, Sanat Kumar Mahanta, Krishna Kumar Singh, Prakash K. Jha, PV Vara Prasad, Manoj Kumar Srivastava, Rohit Katiyar

“…This study identified sugar rich (>7 % on dry matter basis) accessions of Sehima nervosum (SN), which is adequate to initiate lactic acid production during ensiling. Sehima is a prominent range grass of Sehima-Dichatnthium grasslands in India followed by Africa, Pakistan, China and Australia. …”
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Fhl1, a new spatially specific protein, regulates vein graft neointimal hyperplasia by Chaoqun Wang, Jiantao Chen, Zicong Feng, Bohao Jian, Suiqing Huang, Kangni Feng, Haoliang Liu, Zhuoming Zhou, Ziyin Ye, Jing Lu, Mengya Liang, Zhongkai Wu

“…It has thus far the highest enrichment of expression in the neointima in NIH phases, suggesting that it is a prominent molecular biomarker of neointima. We generated rats with a Fhl1 deletion and found that insufficient Fhl1 expression caused an increase in the severity of vascular inflammation and proliferation during neointimal hyperplasia. …”
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Investigating the Impact of Order Flow Imbalance and Information Asymmetry on Treasury Bill Price Changes by Ali Namaki, Aysa Kazemi bavil

“…Given the critical role of information asymmetry and its effects on traders' order behavior, the study of orders—rather than mere transactions—has gained prominence. Analyzing traders' behavioral patterns through their order prices, volumes, and types provides a clearer understanding of the price effects resulting from market participants' decisions. …”
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Short- and long-term changes in neurological, behavioural, and blood biomarkers following repeated mild traumatic brain injury in rats—potential biological sex-dependent effects by Rodrigo Moraga-Amaro, Oscar Moreno, Jordi Llop, Marion Bankstahl, Marion Bankstahl, Jens P. Bankstahl

“…To determine long-term changes in tau aggregation as a hallmark of CTE, we used [18F]-florzolotau (florzolotau) autoradiography in brain slices.ResultsBoth short-term weight gain and time-to-right after rmTBI were increased in grouped animals, with male rats showing more prominent changes. The neurological state was impaired after each mTBI and still 12 weeks later, independent of the sex. …”
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KIRAAT İLMİ TEDRİSATINDA RUMUZ KULLANIMINA DAİR BİR İNCELEME by Selim Çakıroğlu

“…Kıraatlere dair yazılmış eserler ise bu ilmin sistematik ve müdellel bir şekilde alınmasına yardımcı olur. …”
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Strategic foresight of staffing needs of innovative development of socio-economic systems by Elena Okunkova

“…A number of methodological problems of the existing systems of providing innovative economy in a personnel has been revealed, described and systematized: the forecast of balance of a labor resources does not consider changes of working conditions, modernization of production assets and new technologies; planning of target figures of enrollment of students for master programs is performed in a separation from real personnel requirements; lack of criteria system of detection of competence-based requirements of innovative economy; the imminent need of transition from scenario approach of forecasting of needs of economy for professional staff to approach “a threefold spiral”. …”
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Latvia and Estonia's View to the Separation of Klaipėda from Lithuania in 1939 by Zenonas Butkus, Magnus llmjärv

“…The loss of Klaipėda was considered by Estonia as an inevitable and imminent event, whereas Latvia treated it as a reprehensible fact of German expansion that Lithuania had to face and experience. …”
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Multidimensional 1-Year Outcomes After Intensive Care Admission for Multisystem Inflammatory Syndrome in Children by Thomas C. Seijbel, BSc, Levi Hoste, MD, Corinne M. P. Buysse, MD, PhD, Karolijn Dulfer, PhD, Filomeen Haerynck, MD, PhD, Matthijs de Hoog, MD, PhD, Naomi Ketharanathan, MD, PhD

“…Seventy MIS-C patients (62% male; median age, 10.0 [interquartile range, 7.4–13.0]) were admitted to the PICU, mostly (86%) due to (imminent) circulatory failure. The majority received IV immunoglobulins (95%), steroids (83%), and vasopressors and/or inotropes (72%). …”
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The People's Commissariat of Foreign Affairs (NKID) of the USSR in the City of Kuibyshev (1941-1943) by S. I. Chernyavsky

“…Among other tasks were the search for allies, establishing effective military, economic and political cooperation with them, counteracting the expansion of the Nazi coalition at the expense of Sweden and Turkey, and conducting an extremely balanced policy in the Far East in order to avoid a military clash with Japan.Due to the deterioration of the military situation on the Western Front and the imminence of the capture of Moscow, on October 16, 1941, the main staff of the People's Commissariat for Foreign Affairs, headed by its Deputy Chairman A. …”
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The Prevalence of Dermoscopy Use Among Dermatology Residents in Riyadh, Saudi Arabia: Cross-Sectional Study by Abdullah Almeziny, Rahaf Almutairi, Amal Altamimi, Khloud Alshehri, Latifah Almehaideb, Asem Shadid, Mohammed Al Mashali

“… Abstract BackgroundDermoscopy is a noninvasive technology used to examine the skin’s invisible microstructures in dermatological practice and is gaining prominence as a crucial tool. Dermoscopy is an evidence-based practice used to enhance the early detection of skin malignancies and to help distinguish between various skin conditions, including pigmented and nonpigmented skin malignancies. …”
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Effects of 24 Weeks of Growth Hormone Treatment on Bone Microstructure and Volumetric Bone Density in Patients with Childhood-Onset Adult GH Deficiency by Hongbo Yang, Kemin Yan, Yuping Xu, Linjie Wang, Qi Zhang, Fengying Gong, Huijuan Zhu, Weibo Xia, Hui Pan

“…Adults with childhood-onset growth hormone deficiency (CO AGHD) have prominently impaired volumetric bone density (vBMD) and bone microarchitecture. …”
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